Science 30 November 1990: Vol. 250. no. 4985, pp. 1233 - 1238 DOI: 10.1126/science.1978757

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Articles

DNA double-strand break repair activities in mammary epithelial cells--influence of endogenous p53 variants.

M. Keimling and L. Wiesmuller (2009)
Carcinogenesis 30, 1260-1268
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Prevention: From 1727 to Milestones of the Past 100 Years.

S. M. Lippman and E. T. Hawk (2009)
Cancer Res. 69, 5269-5284
 |  Abstract »  |  Full Text »  |  PDF »

Type I natural killer T cells suppress tumors caused by p53 loss in mice.

J. B. Swann, A. P. Uldrich, S. van Dommelen, J. Sharkey, W. K. Murray, D. I. Godfrey, and M. J. Smyth (2009)
Blood 113, 6382-6385
 |  Abstract »  |  Full Text »  |  PDF »

PRMT5 is required for cell-cycle progression and p53 tumor suppressor function.

A. Scoumanne, J. Zhang, and X. Chen (2009)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Prevention Research: Back to the Future.

S. M. Lippman (2009)
Cancer Prevention Research 2, 503-513
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Effect of TP53 Arg72Pro and MDM2 SNP309 Polymorphisms on the Risk of High-Grade Osteosarcoma Development and Survival.

G. Toffoli, P. Biason, A. Russo, E. De Mattia, E. Cecchin, C. M. Hattinger, M. Pasello, M. Alberghini, C. Ferrari, K. Scotlandi, et al. (2009)
Clin. Cancer Res. 15, 3550-3556
 |  Abstract »  |  Full Text »  |  PDF »

Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer.

J. M. Schildkraut, E. L. Goode, M. A. Clyde, E. S. Iversen, P. G. Moorman, A. Berchuck, J. R. Marks, J. Lissowska, L. Brinton, B. Peplonska, et al. (2009)
Cancer Res. 69, 2349-2357
 |  Abstract »  |  Full Text »  |  PDF »

Beyond Li Fraumeni Syndrome: Clinical Characteristics of Families With p53 Germline Mutations.

K. D. Gonzalez, K. A. Noltner, C. H. Buzin, D. Gu, C. Y. Wen-Fong, V. Q. Nguyen, J. H. Han, K. Lowstuter, J. Longmate, S. S. Sommer, et al. (2009)
J. Clin. Oncol. 27, 1250-1256
 |  Abstract »  |  Full Text »  |  PDF »

The History of Tumor Virology.

R. T. Javier and J. S. Butel (2008)
Cancer Res. 68, 7693-7706
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Identification of a novel TP53 germline mutation E285V in a rare case of paediatric adrenocortical carcinoma and choroid plexus carcinoma.

A Russell-Swetek, A N West, J E Mintern, J Jenkins, C Rodriguez-Galindo, R Ribeiro, and G P Zambetti (2008)
J. Med. Genet. 45, 603-606
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Counseling and Testing for Common Hereditary Breast Cancer Syndromes: A Paper from the 2007 William Beaumont Hospital Symposium on Molecular Pathology.

D. C. Allain (2008)
J. Mol. Diagn. 10, 383-395
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The Pleiotropic Phenotype of Apc Mutations in the Mouse: Allele Specificity and Effects of the Genetic Background.

R. B. Halberg, X. Chen, J. M. Amos-Landgraf, A. White, K. Rasmussen, L. Clipson, C. Pasch, R. Sullivan, H. C. Pitot, and W. F. Dove (2008)
Genetics 180, 601-609
 |  Abstract »  |  Full Text »  |  PDF »

Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome.

A. Shlien, U. Tabori, C. R. Marshall, M. Pienkowska, L. Feuk, A. Novokmet, S. Nanda, H. Druker, S. W. Scherer, and D. Malkin (2008)
PNAS 105, 11264-11269
 |  Abstract »  |  Full Text »  |  PDF »

Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families.

G Bougeard, R Sesboue, S Baert-Desurmont, S Vasseur, C Martin, J Tinat, L Brugieres, A Chompret, B B.-d. Paillerets, D Stoppa-Lyonnet, et al. (2008)
J. Med. Genet. 45, 535-538
 |  Abstract »  |  Full Text »  |  PDF »

The Previously Undescribed ZKSCAN3 (ZNF306) Is a Novel "Driver" of Colorectal Cancer Progression.

L. Yang, S. R. Hamilton, A. Sood, T. Kuwai, L. Ellis, A. Sanguino, G. Lopez-Berestein, and D. D. Boyd (2008)
Cancer Res. 68, 4321-4330
 |  Abstract »  |  Full Text »  |  PDF »

MDM2 SNP309 Is Associated With Poor Outcome in B-Cell Chronic Lymphocytic Leukemia.

I. Gryshchenko, S. Hofbauer, M. Stoecher, P. T. Daniel, M. Steurer, A. Gaiger, K. Eigenberger, R. Greil, and I. Tinhofer (2008)
J. Clin. Oncol. 26, 2252-2257
 |  Abstract »  |  Full Text »  |  PDF »

Interferon Regulatory Factors IRF5 and IRF7 Inhibit Growth and Induce Senescence in Immortal Li-Fraumeni Fibroblasts.

Q. Li, L. Tang, P. C. Roberts, J. M. Kraniak, A. L. Fridman, O. I. Kulaeva, O. S. Tehrani, and M. A. Tainsky (2008)
Mol. Cancer Res. 6, 770-784
 |  Abstract »  |  Full Text »  |  PDF »

Risk Stratification in Cancer Predisposition Syndromes: Lessons Learned from Novel Molecular Developments in Li-Fraumeni Syndrome.

U. Tabori and D. Malkin (2008)
Cancer Res. 68, 2053-2057
 |  Abstract »  |  Full Text »  |  PDF »

LY2109761, a novel transforming growth factor {beta} receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis.

D. Melisi, S. Ishiyama, G. M. Sclabas, J. B. Fleming, Q. Xia, G. Tortora, J. L. Abbruzzese, and P. J. Chiao (2008)
Mol. Cancer Ther. 7, 829-840
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative analysis of robustness and fragility in biological networks based on feedback dynamics.

Y.-K. Kwon and K.-H. Cho (2008)
Bioinformatics 24, 987-994
 |  Abstract »  |  Full Text »  |  PDF »

F18-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography Screening in Li-Fraumeni Syndrome.

S. Masciari, A. D. Van den Abbeele, L. R. Diller, I. Rastarhuyeva, J. Yap, K. Schneider, L. Digianni, F. P. Li, J. F. Fraumeni Jr, S. Syngal, et al. (2008)
JAMA 299, 1315-1319
 |  Abstract »  |  Full Text »  |  PDF »

Epigenetics at the Epicenter of Modern Medicine.

A. P. Feinberg (2008)
JAMA 299, 1345-1350
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced expression of aromatase in p53-inactivated mammary epithelial cells.

H. K. Choi, S. H. Roh, H. G. Kim, E. H. Han, H. G. Jeong, and K. W. Kang (2008)
Endocr. Relat. Cancer 15, 139-147
 |  Abstract »  |  Full Text »  |  PDF »

Mutational Analysis of Thirty-two Double-Strand DNA Break Repair Genes in Breast and Pancreatic Cancers.

X. Wang, C. Szabo, C. Qian, P. G. Amadio, S. N. Thibodeau, J. R. Cerhan, G. M. Petersen, W. Liu, and F. J. Couch (2008)
Cancer Res. 68, 971-975
 |  Abstract »  |  Full Text »  |  PDF »

Translation of Genetic Discoveries into Clinical Therapies.

D. G. Hackam and A. S. Hackam (2008)
Ann Intern Med 148, 246-247
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Adrenocortical carcinoma survival rates correlated to genomic copy number variants.

E. A. Stephan, T.-H. Chung, C. S. Grant, S. Kim, D. D. Von Hoff, J. M. Trent, and M. J. Demeure (2008)
Mol. Cancer Ther. 7, 425-431
 |  Abstract »  |  Full Text »  |  PDF »

Is CHEK2 a cause of the Li Fraumeni syndrome?.

D G Evans, J M Birch, and S A Narod (2008)
J. Med. Genet. 45, 63-64
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p53: It Has It All, But Will It Make It to the Clinic As a Marker in Bladder Cancer?.

F. X. Real (2007)
J. Clin. Oncol. 25, 5341-5344
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Malignant astrocytic glioma: genetics, biology, and paths to treatment.

F. B. Furnari, T. Fenton, R. M. Bachoo, A. Mukasa, J. M. Stommel, A. Stegh, W. C. Hahn, K. L. Ligon, D. N. Louis, C. Brennan, et al. (2007)
Genes & Dev. 21, 2683-2710
 |  Abstract »  |  Full Text »  |  PDF »

Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older populations.

Z. Feng, W. Hu, A. K. Teresky, E. Hernando, C. Cordon-Cardo, and A. J. Levine (2007)
PNAS 104, 16633-16638
 |  Abstract »  |  Full Text »  |  PDF »

The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.

M. Reimann, C. Loddenkemper, C. Rudolph, I. Schildhauer, B. Teichmann, H. Stein, B. Schlegelberger, B. Dorken, and C. A. Schmitt (2007)
Blood 110, 2996-3004
 |  Abstract »  |  Full Text »  |  PDF »

Trans-generational epistasis between Dnd1Ter and other modifier genes controls susceptibility to testicular germ cell tumors.

M.-Y. J. Lam, J. D. Heaney, K. K. Youngren, J. H. Kawasoe, and J. H. Nadeau (2007)
Hum. Mol. Genet. 16, 2233-2240
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer.

M. Yang, Y. Guo, X. Zhang, X. Miao, W. Tan, T. Sun, D. Zhao, D. Yu, J. Liu, and D. Lin (2007)
Carcinogenesis 28, 1996-2001
 |  Abstract »  |  Full Text »  |  PDF »

Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.

H. Yamada, K. Shinmura, K. Okudela, M. Goto, M. Suzuki, K. Kuriki, T. Tsuneyoshi, and H. Sugimura (2007)
Carcinogenesis 28, 2013-2018
 |  Abstract »  |  Full Text »  |  PDF »

Genetic variation in TP53 and risk of breast cancer in a population-based case control study.

B. L. Sprague, A. Trentham-Dietz, M. Garcia-Closas, P. A. Newcomb, L. Titus-Ernstoff, J. M. Hampton, S. J. Chanock, J. L. Haines, and K. M. Egan (2007)
Carcinogenesis 28, 1680-1686
 |  Abstract »  |  Full Text »  |  PDF »

MDM2 SNP309 Polymorphism as Risk Factor for Susceptibility and Poor Prognosis in Renal Cell Carcinoma.

H. Hirata, Y. Hinoda, N. Kikuno, K. Kawamoto, Y. Suehiro, Y. Tanaka, and R. Dahiya (2007)
Clin. Cancer Res. 13, 4123-4129
 |  Abstract »  |  Full Text »  |  PDF »

Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish.

X. Le, D. M. Langenau, M. D. Keefe, J. L. Kutok, D. S. Neuberg, and L. I. Zon (2007)
PNAS 104, 9410-9415
 |  Abstract »  |  Full Text »  |  PDF »

Dominant-Negative but not Gain-of-Function Effects of a p53.R270H Mutation in Mouse Epithelium Tissue after DNA Damage.

S. W.P. Wijnhoven, E. N. Speksnijder, X. Liu, E. Zwart, C. Th. M. vanOostrom, R. B. Beems, E. M. Hoogervorst, M. M. Schaap, L. D. Attardi, T. Jacks, et al. (2007)
Cancer Res. 67, 4648-4656
 |  Abstract »  |  Full Text »  |  PDF »

p53 therapy in a patient with Li-Fraumeni syndrome.

N. Senzer, J. Nemunaitis, M. Nemunaitis, J. Lamont, M. Gore, H. Gabra, R. Eeles, N. Sodha, F. J. Lynch, L. A. Zumstein, et al. (2007)
Mol. Cancer Ther. 6, 1478-1482
 |  Abstract »  |  Full Text »  |  PDF »

Orbital Rhabdomyosarcoma in Li-Fraumeni Syndrome.

D. Y. Chong, H. Demirci, S. M. Ronan, A. Flint, and V. M. Elner (2007)
Arch Ophthalmol 125, 566-569
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Younger Age of Cancer Initiation Is Associated with Shorter Telomere Length in Li-Fraumeni Syndrome.

U. Tabori, S. Nanda, H. Druker, J. Lees, and D. Malkin (2007)
Cancer Res. 67, 1415-1418
 |  Abstract »  |  Full Text »  |  PDF »

Gene Expression Profiling of Childhood Adrenocortical Tumors.

A. N. West, G. A. Neale, S. Pounds, B. C. Figueredo, C. Rodriguez Galindo, M. A. D. Pianovski, A. G. Oliveira Filho, D. Malkin, E. Lalli, R. Ribeiro, et al. (2007)
Cancer Res. 67, 600-608
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of p53 Localization and Activity by Ubc13.

A. Laine, I. Topisirovic, D. Zhai, J. C. Reed, K. L. B. Borden, and Z. Ronai (2006)
Mol. Cell. Biol. 26, 8901-8913
 |  Abstract »  |  Full Text »  |  PDF »

Radiation clastogenesis and cell cycle checkpoint function as functional markers of breast cancer risk.

W. K. Kaufmann, L. Filatov, S. E. Oglesbee, D. A. Simpson, M. A. Lotano, H. D. McKeen, L. R. Sawyer, D. T. Moore, R. C. Millikan, M. Cordeiro-Stone, et al. (2006)
Carcinogenesis 27, 2519-2527
 |  Abstract »  |  Full Text »  |  PDF »

Ionizing radiation induces caspase-dependent but Chk2- and p53-independent cell death in Drosophila melanogaster.

A. Wichmann, B. Jaklevic, and T. T. Su (2006)
PNAS 103, 9952-9957
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Germ Line Variant Hotspot Mutant p53-R175L in Pediatric Adrenal Cortical Carcinoma..

A. N. West, R. C. Ribeiro, J. Jenkins, C. Rodriguez-Galindo, B. C. Figueiredo, R. Kriwacki, and G. P. Zambetti (2006)
Cancer Res. 66, 5056-5062
 |  Abstract »  |  Full Text »  |  PDF »

MDM2 SNP309 Accelerates Tumor Formation in a Gender-Specific and Hormone-Dependent Manner..

G. L. Bond, K. M. Hirshfield, T. Kirchhoff, G. Alexe, E. E. Bond, H. Robins, F. Bartel, H. Taubert, P. Wuerl, W. Hait, et al. (2006)
Cancer Res. 66, 5104-5110
 |  Abstract »  |  Full Text »  |  PDF »

Phase I, Pharmacokinetic, and Pharmacodynamic Study of Intravenously Administered Ad5CMV-p53, an Adenoviral Vector Containing the Wild-Type p53 Gene, in Patients With Advanced Cancer.

A. W. Tolcher, D. Hao, J. de Bono, A. Miller, A. Patnaik, L. A. Hammond, L. Smetzer, J. Van Wart Hood, J. Merritt, E. K. Rowinsky, et al. (2006)
J. Clin. Oncol. 24, 2052-2058
 |  Abstract »  |  Full Text »  |  PDF »

p53 Biological Network: Chronic Inflammation and Cancer.

S. P. Hussain and C. C. Harris (2006)
Am. Assoc. Cancer Res. Educ. Book 2006, 249-254
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Spontaneous and Irradiation-Induced Tumor Susceptibility in Brca2 Germline Mutant Mice and Cooperative Effects with a p53 Germline Mutation.

K. A. McAllister, C. D. Houle, J. Malphurs, T. Ward, N. K. Collins, W. Gersch, L. Wharey, J. C. Seely, L. Betz, L. M. Bennett, et al. (2006)
Toxicol Pathol 34, 187-198
 |  Abstract »  |  Full Text »  |  PDF »

Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo.

H Caldas, M P Holloway, B M Hall, S J Qualman, and R A Altura (2006)
J. Med. Genet. 43, 119-128
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Survivorship--Genetic Susceptibility and Second Primary Cancers: Research Strategies and Recommendations.

L. B. Travis, C. S. Rabkin, L. M. Brown, J. M. Allan, B. P. Alter, C. B. Ambrosone, C. B. Begg, N. Caporaso, S. Chanock, A. DeMichele, et al. (2006)
J Natl Cancer Inst 98, 15-25
 |  Abstract »  |  Full Text »  |  PDF »

Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation.

B C Figueiredo, R Sandrini, G P Zambetti, R M Pereira, C Cheng, W Liu, L Lacerda, M A Pianovski, E Michalkiewicz, J Jenkins, et al. (2006)
J. Med. Genet. 43, 91-96
 |  Abstract »  |  Full Text »  |  PDF »

Tumor suppressor genetics.

S. R. Payne and C. J. Kemp (2005)
Carcinogenesis 26, 2031-2045
 |  Abstract »  |  Full Text »  |  PDF »

Detection of functional single-nucleotide polymorphisms that affect apoptosis.

S. L. Harris, G. Gil, H. Robins, W. Hu, K. Hirshfield, E. Bond, G. Bond, and A. J. Levine (2005)
PNAS 102, 16297-16302
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Ablation of Protein Tyrosine Phosphatase 1B Accelerates Lymphomagenesis of p53-Null Mice through the Regulation of B-Cell Development.

N. Dube, A. Bourdeau, K. M. Heinonen, A. Cheng, A. Lee Loy, and M. L. Tremblay (2005)
Cancer Res. 65, 10088-10095
 |  Abstract »  |  Full Text »  |  PDF »

The Role of P53 and MDM2 Polymorphisms in the Risk of Esophageal Squamous Cell Carcinoma.

Y. Hong, X. Miao, X. Zhang, F. Ding, A. Luo, Y. Guo, W. Tan, Z. Liu, and D. Lin (2005)
Cancer Res. 65, 9582-9587
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Invasive Mouse Skin Carcinomas in Transgenic Mice with Mutations in Both H-ras and p53.

Z. Zhang, R. Yao, J. Li, Y. Wang, C. W. Boone, R. A. Lubet, and M. You (2005)
Mol. Cancer Res. 3, 563-574
 |  Abstract »  |  Full Text »  |  PDF »

p53 Genotypes and Risk of Glioma and Meningioma.

B. Malmer, M. Feychting, S. Lonn, A. Ahlbom, and R. Henriksson (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 2220-2223
 |  Abstract »  |  Full Text »  |  PDF »

Saccharomyces cerevisiae as a Model System To Define the Chromosomal Instability Phenotype.

C. D. Putnam, V. Pennaneach, and R. D. Kolodner (2005)
Mol. Cell. Biol. 25, 7226-7238
 |  Abstract »  |  Full Text »  |  PDF »

Restarting the Cell Cycle When the Checkpoint Comes to a Halt.

M. A.T.M. van Vugt, A. Bras, and R. H. Medema (2005)
Cancer Res. 65, 7037-7040
 |  Abstract »  |  Full Text »  |  PDF »

Increased Risk of Cancer among Siblings of Long-term Childhood Cancer Survivors: A Report from the Childhood Cancer Survivor Study.

D. L. Friedman, N. S. Kadan-Lottick, J. Whitton, A. C. Mertens, Y. Yasui, Y. Liu, A. T. Meadows, L. L. Robison, and L. C. Strong (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 1922-1927
 |  Abstract »  |  Full Text »  |  PDF »

Rhabdomyosarcoma: New Windows of Opportunity.

P. P. Breitfeld and W. H. Meyer (2005)
Oncologist 10, 518-527
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Nuclear Export in Human Papillomavirus Type 18 E6-Mediated Ubiquitination and Degradation of p53.

D. Stewart, A. Ghosh, and G. Matlashewski (2005)
J. Virol. 79, 8773-8783
 |  Abstract »  |  Full Text »  |  PDF »

Differential Recognition of Response Elements Determines Target Gene Specificity for p53 and p63.

M. Osada, H. L. Park, Y. Nagakawa, K. Yamashita, A. Fomenkov, M. S. Kim, G. Wu, S. Nomoto, B. Trink, and D. Sidransky (2005)
Mol. Cell. Biol. 25, 6077-6089
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Programs following Genetic Alterations in p53, INK4A, and H-Ras Genes along Defined Stages of Malignant Transformation.

M. Milyavsky, Y. Tabach, I. Shats, N. Erez, Y. Cohen, X. Tang, M. Kalis, I. Kogan, Y. Buganim, N. Goldfinger, et al. (2005)
Cancer Res. 65, 4530-4543
 |  Abstract »  |  Full Text »  |  PDF »

Increased Rates of Chromosome Breakage in BRCA1 Carriers Are Normalized by Oral Selenium Supplementation.

E. Kowalska, S. A. Narod, T. Huzarski, S. Zajaczek, J. Huzarska, B. Gorski, and J. Lubinski (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 1302-1306
 |  Abstract »  |  Full Text »  |  PDF »

TP53 Mutations and Outcome in Osteosarcoma: A Prospective, Multicenter Study.

J. S. Wunder, N. Gokgoz, R. Parkes, S. B. Bull, S. Eskandarian, A. M. Davis, C. P. Beauchamp, E. U. Conrad, R. J. Grimer, J. H. Healey, et al. (2005)
J. Clin. Oncol. 23, 1483-1490
 |  Abstract »  |  Full Text »  |  PDF »

Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility.

S. Kammerer, R. B. Roth, C. R. Hoyal, R. Reneland, G. Marnellos, M. Kiechle, U. Schwarz-Boeger, L. R. Griffiths, F. Ebner, J. Rehbock, et al. (2005)
PNAS 102, 2004-2009
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Mapping of a Third Li-Fraumeni Syndrome Predisposition Locus to Human Chromosome 1q23.

L. L. Bachinski, S.-E. Olufemi, X. Zhou, C.-C. Wu, L. Yip, S. Shete, G. Lozano, C. I. Amos, L. C. Strong, and R. Krahe (2005)
Cancer Res. 65, 427-431
 |  Abstract »  |  Full Text »  |  PDF »

tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.

S. Berghmans, R. D. Murphey, E. Wienholds, D. Neuberg, J. L. Kutok, C. D. M. Fletcher, J. P. Morris, T. X. Liu, S. Schulte-Merker, J. P. Kanki, et al. (2005)
PNAS 102, 407-412
 |  Abstract »  |  Full Text »  |  PDF »

Surgical Prevention of Cancer.

M. M. Bertagnolli (2005)
J. Clin. Oncol. 23, 324-332
 |  Abstract »  |  Full Text »  |  PDF »

Single-Nucleotide Polymorphisms in the p53 Pathway.

S.L. HARRIS, G. GIL, W. HU, H. ROBINS, E. BOND, K. HIRSHFIELD, Z. FENG, X. YU, A.K. TERESKY, G. BOND, et al. (2005)
Cold Spring Harb Symp Quant Biol 70, 111-119
 |  Abstract »  |  PDF »

PDBSite: a database of the 3D structure of protein functional sites.

V. A. Ivanisenko, S. S. Pintus, D. A. Grigorovich, and N. A. Kolchanov (2005)
Nucleic Acids Res. 33, D183-D187
 |  Abstract »  |  Full Text »  |  PDF »

Ductal Lavage and Risk Assessment of Breast Cancer.

B. Arun (2004)
Oncologist 9, 599-605
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Human p53 Activity and Cell Localization by Alternative Splicing.

A. Ghosh, D. Stewart, and G. Matlashewski (2004)
Mol. Cell. Biol. 24, 7987-7997
 |  Abstract »  |  Full Text »  |  PDF »

Germ Line BAX Alterations Are Infrequent in Li-Fraumeni Syndrome.

J. W. Barlow, M. Mous, J. C. Wiley, J. M. Varley, G. Lozano, L. C. Strong, and D. Malkin (2004)
Cancer Epidemiol. Biomarkers Prev. 13, 1403-1406
 |  Abstract »  |  Full Text »  |  PDF »

Oncogenes and Tumor Suppressor Genes in Breast Cancer: Potential Diagnostic and Therapeutic Applications.

C. Osborne, P. Wilson, and D. Tripathy (2004)
Oncologist 9, 361-377
 |  Abstract »  |  Full Text »  |  PDF »

Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients.

G Keller, H Vogelsang, I Becker, S Plaschke, K Ott, G Suriano, A R Mateus, R Seruca, K Biedermann, D Huntsman, et al. (2004)
J. Med. Genet. 41, e89
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Collaboration of Brca1 and Chk2 in tumorigenesis.

J. P. McPherson, B. Lemmers, A. Hirao, A. Hakem, J. Abraham, E. Migon, E. Matysiak-Zablocki, L. Tamblyn, O. Sanchez-Sweatman, R. Khokha, et al. (2004)
Genes & Dev. 18, 1144-1153
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Sex steroidal regulation of uterine leiomyoma growth and apoptosis.

T. Maruo, N. Ohara, J. Wang, and H. Matsuo (2004)
Hum. Reprod. Update 10, 207-220
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Genetic Predisposition to Lung Cancer.

A. G. Schwartz (2004)
Chest 125, 86S-89S
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Predictive Models for Breast Cancer Susceptibility from Multiple Single Nucleotide Polymorphisms.

J. Listgarten, S. Damaraju, B. Poulin, L. Cook, J. Dufour, A. Driga, J. Mackey, D. Wishart, R. Greiner, and B. Zanke (2004)
Clin. Cancer Res. 10, 2725-2737
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Recognition and Management of Hereditary Breast Cancer Syndromes.

D. L. Thull and V. G. Vogel (2004)
Oncologist 9, 13-24
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Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary.

R. Gorlick, P. Anderson, I. Andrulis, C. Arndt, G. P. Beardsley, M. Bernstein, J. Bridge, N.-K. Cheung, J. S. Dome, D. Ebb, et al. (2003)
Clin. Cancer Res. 9, 5442-5453
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Immunohistochemical Expression of p53, Fibroblast Growth Factor-b, and Transforming Growth Factor-{alpha} in Feline Vaccine-associated Sarcomas.

A. Nieto, M. A. Sanchez, E. Martinez, and E. Rollan (2003)
Vet. Pathol. 40, 651-658
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Li-Fraumeni and Related Syndromes: Correlation between Tumor Type, Family Structure, and TP53 Genotype.

M. Olivier, D. E. Goldgar, N. Sodha, H. Ohgaki, P. Kleihues, P. Hainaut, and R. A. Eeles (2003)
Cancer Res. 63, 6643-6650
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Rad53 Phosphorylation Site Clusters Are Important for Rad53 Regulation and Signaling.

S.-J. Lee, M. F. Schwartz, J. K. Duong, and D. F. Stern (2003)
Mol. Cell. Biol. 23, 6300-6314
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{alpha}-Galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis.

Y. Hayakawa, S. Rovero, G. Forni, and M. J. Smyth (2003)
PNAS 100, 9464-9469
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Paradoxical Upregulation of Tumor Suppressor Protein p53 in Serum-Stimulated Vascular Smooth Muscle Cells: A Novel Negative-Feedback Regulatory Mechanism.

Z. H. Mnjoyan, R. Dutta, D. Zhang, B.-B. Teng, and K. Fujise (2003)
Circulation 108, 464-471
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A Role for the Phosphorylation of hRad9 in Checkpoint Signaling.

R. P. St.Onge, B. D. A. Besley, J. L. Pelley, and S. Davey (2003)
J. Biol. Chem. 278, 26620-26628
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Reovirus Prolongs Survival and Reduces the Frequency of Spinal and Leptomeningeal Metastases from Medulloblastoma.

W. Q. Yang, D. Senger, H. Muzik, Z. Q. Shi, D. Johnson, P. M. A. Brasher, N. B. Rewcastle, M. Hamilton, J. Rutka, J. Wolff, et al. (2003)
Cancer Res. 63, 3162-3172
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Activin Induces x-Zone Apoptosis That Inhibits Luteinizing Hormone-Dependent Adrenocortical Tumor Formation in Inhibin-Deficient Mice.

F. Beuschlein, B. D. Looyenga, S. E. Bleasdale, C. Mutch, D. L. Bavers, A. F. Parlow, J. H. Nilson, and G. D. Hammer (2003)
Mol. Cell. Biol. 23, 3951-3964
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Germline TP53 mutations in breast cancer families with multiple primary cancers: is TP53 a modifier of BRCA1?.

A-M Martin, P A Kanetsky, B Amirimani, T A Colligon, G Athanasiadis, H A Shih, M R Gerrero, K Calzone, T R Rebbeck, and B L Weber (2003)
J. Med. Genet. 40, e34-34
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Absence of constitutional H2AX gene mutations in 101 hereditary breast cancer families.

A N A Monteiro, S Zhang, C M Phelan, and S A Narod (2003)
J. Med. Genet. 40, e51-51
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A novel case with germline p53 gene mutation having concurrent multiple primary colon tumours.

M Miyaki, T Iijima, M Ohue, Y Kita, T Hishima, T Kuroki, T Iwama, and T Mori (2003)
Gut 52, 304-306
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Psychosocial Predictors of BRCA Counseling and Testing Decisions among Urban African-American Women.

H. S. Thompson, H. B. Valdimarsdottir, C. Duteau-Buck, J. Guevarra, D. H. Bovbjerg, C. Richmond-Avellaneda, D. Amarel, D. Godfrey, K. Brown, and K. Offit (2002)
Cancer Epidemiol. Biomarkers Prev. 11, 1579-1585
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The Molecular Pathogenesis of Hereditary and Sporadic Adrenocortical and Adrenomedullary Tumors.

C. A. Koch, K. Pacak, and G. P. Chrousos (2002)
J. Clin. Endocrinol. Metab. 87, 5367-5384
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Risk assessment and management of high risk familial breast cancer.

D G R Evans and F Lalloo (2002)
J. Med. Genet. 39, 865-871
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Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53.

H. Yoon, S. Liyanarachchi, F. A. Wright, R. Davuluri, J. C. Lockman, A. de la Chapelle, and N. S. Pellegata (2002)
PNAS 99, 15632-15637
 |  Abstract »  |  Full Text »  |  PDF »

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