Science 23 November 1990: Vol. 250. no. 4984, pp. 1139 - 1142 DOI: 10.1126/science.2251501

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Articles

Identification of a Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Variant Resistant to Cold Inactivation.

A. Kassa, A. Finzi, M. Pancera, J. R. Courter, A. B. Smith III, and J. Sodroski (2009)
J. Virol. 83, 4476-4488
 |  Abstract »  |  Full Text »  |  PDF »

Reverse Transcriptase Inhibitors as Potential Colorectal Microbicides.

C. Herrera, M. Cranage, I. McGowan, P. Anton, and R. J. Shattock (2009)
Antimicrob. Agents Chemother. 53, 1797-1807
 |  Abstract »  |  Full Text »  |  PDF »

Conserved Salt Bridge between the N- and C-Terminal Heptad Repeat Regions of the Human Immunodeficiency Virus Type 1 gp41 Core Structure Is Critical for Virus Entry and Inhibition.

Y. He, S. Liu, J. Li, H. Lu, Z. Qi, Z. Liu, A. K. Debnath, and S. Jiang (2008)
J. Virol. 82, 11129-11139
 |  Abstract »  |  Full Text »  |  PDF »

pH-Induced Activation of Arenavirus Membrane Fusion Is Antagonized by Small-Molecule Inhibitors.

J. York, D. Dai, S. M. Amberg, and J. H. Nunberg (2008)
J. Virol. 82, 10932-10939
 |  Abstract »  |  Full Text »  |  PDF »

Sequestering of the Prehairpin Intermediate of gp41 by Peptide N36Mut(e,g) Potentiates the Human Immunodeficiency Virus Type 1 Neutralizing Activity of Monoclonal Antibodies Directed against the N-Terminal Helical Repeat of gp41.

E. Gustchina, C. A Bewley, and G. M. Clore (2008)
J. Virol. 82, 10032-10041
 |  Abstract »  |  Full Text »  |  PDF »

Monitoring Early Fusion Dynamics of Human Immunodeficiency Virus Type 1 at Single-Molecule Resolution.

T. M. Dobrowsky, Y. Zhou, S. X. Sun, R. F. Siliciano, and D. Wirtz (2008)
J. Virol. 82, 7022-7033
 |  Abstract »  |  Full Text »  |  PDF »

Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region.

M. Kozisek, K. G. Saskova, P. Rezacova, J. Brynda, N. M. van Maarseveen, D. De Jong, C. A. Boucher, R. M. Kagan, M. Nijhuis, and J. Konvalinka (2008)
J. Virol. 82, 5869-5878
 |  Abstract »  |  Full Text »  |  PDF »

An Alteration of Human Immunodeficiency Virus gp41 Leads to Reduced CCR5 Dependence and CD4 Independence.

B. M. Taylor, J. S. Foulke, R. Flinko, A. Heredia, A. DeVico, and M. Reitz (2008)
J. Virol. 82, 5460-5471
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Membrane-Spanning Domain of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein in Cell-Cell Fusion and Virus Infection.

L. Shang, L. Yue, and E. Hunter (2008)
J. Virol. 82, 5417-5428
 |  Abstract »  |  Full Text »  |  PDF »

The function of coreceptor as a basis for the kinetic dissection of HIV type 1 envelope protein-mediated cell fusion.

M.-P. Chien, S. Jiang, and D.-K. Chang (2008)
FASEB J 22, 1179-1192
 |  Abstract »  |  Full Text »  |  PDF »

Predominant Mode of Human Immunodeficiency Virus Transfer between T Cells Is Mediated by Sustained Env-Dependent Neutralization-Resistant Virological Synapses.

P. Chen, W. Hubner, M. A. Spinelli, and B. K. Chen (2007)
J. Virol. 81, 12582-12595
 |  Abstract »  |  Full Text »  |  PDF »

Sequence of Human Immunodeficiency Virus Type 1 (HIV-1) Gag Localization and Oligomerization Monitored with Live Confocal Imaging of a Replication-Competent, Fluorescently Tagged HIV-1.

W. Hubner, P. Chen, A. D. Portillo, Y. Liu, R. E. Gordon, and B. K. Chen (2007)
J. Virol. 81, 12596-12607
 |  Abstract »  |  Full Text »  |  PDF »

A Covalent Inhibitor Targeting an Intermediate Conformation of the Fusogenic Subunit of the HIV-1 Envelope Complex.

A. Jacobs, O. Quraishi, X. Huang, N. Bousquet-Gagnon, G. Nault, N. Francella, W. G. Alvord, N. Pham, C. Soucy, M. Robitaille, et al. (2007)
J. Biol. Chem. 282, 32406-32413
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory role of CXCR4 glycan in CD4-independent X4-tropic human immunodeficiency virus type 1 infection and its abrogation in CD4-dependent infection.

Y. Kubo, M. Yokoyama, H. Yoshii, C. Mitani, C. Tominaga, Y. Tanaka, H. Sato, and N. Yamamoto (2007)
J. Gen. Virol. 88, 3139-3144
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Restrictions of Human Immunodeficiency Virus Type 1 in Feline Cells.

C. Munk, J. Zielonka, H. Constabel, B.-P. Kloke, B. Rengstl, M. Battenberg, F. Bonci, M. Pistello, M. Lochelt, and K. Cichutek (2007)
J. Virol. 81, 7048-7060
 |  Abstract »  |  Full Text »  |  PDF »

Stability of a Receptor-Binding Active Human Immunodeficiency Virus Type 1 Recombinant gp140 Trimer Conferred by Intermonomer Disulfide Bonding of the V3 Loop: Differential Effects of Protein Disulfide Isomerase on CD4 and Coreceptor Binding.

J. Billington, T. P. Hickling, G. H. Munro, C. Halai, R. Chung, G. G. Dodson, and R. S. Daniels (2007)
J. Virol. 81, 4604-4614
 |  Abstract »  |  Full Text »  |  PDF »

Production and Characterization of High-Affinity Human Monoclonal Antibodies to Human Immunodeficiency Virus Type 1 Envelope Glycoproteins in a Mouse Model Expressing Human Immunoglobulins.

N. C. Sheppard, S. L. Davies, S. A. Jeffs, S. M. Vieira, and Q. J. Sattentau (2007)
Clin. Vaccine Immunol. 14, 157-167
 |  Abstract »  |  Full Text »  |  PDF »

Antibody Binding Is a Dominant Determinant of the Efficiency of Human Immunodeficiency Virus Type 1 Neutralization.

X. Yang, I. Lipchina, S. Cocklin, I. Chaiken, and J. Sodroski (2006)
J. Virol. 80, 11404-11408
 |  Abstract »  |  Full Text »  |  PDF »

Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-{gamma}c-/- mice.

S. Baenziger, R. Tussiwand, E. Schlaepfer, L. Mazzucchelli, M. Heikenwalder, M. O. Kurrer, S. Behnke, J. Frey, A. Oxenius, H. Joller, et al. (2006)
PNAS 103, 15951-15956
 |  Abstract »  |  Full Text »  |  PDF »

Bile Salt-Stimulated Lipase from Human Milk Binds DC-SIGN and Inhibits Human Immunodeficiency Virus Type 1 Transfer to CD4+ T Cells..

M. A. Naarding, A. M. Dirac, I. S. Ludwig, D. Speijer, S. Lindquist, E.-L. Vestman, M. J. Stax, T. B. H. Geijtenbeek, G. Pollakis, O. Hernell, et al. (2006)
Antimicrob. Agents Chemother. 50, 3367-3374
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of HIV-1 Replication by Amphotericin B Methyl Ester: SELECTION FOR RESISTANT VARIANTS.

A. A. Waheed, S. D. Ablan, M. K. Mankowski, J. E. Cummins, R. G. Ptak, C. P. Schaffner, and E. O. Freed (2006)
J. Biol. Chem. 281, 28699-28711
 |  Abstract »  |  Full Text »  |  PDF »

Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion.

G. Frey, S. Rits-Volloch, X.-Q. Zhang, R. T. Schooley, B. Chen, and S. C. Harrison (2006)
PNAS 103, 13938-13943
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Stable Signal Peptide of Junin Arenavirus Envelope Glycoprotein in pH-Dependent Membrane Fusion..

J. York and J. H. Nunberg (2006)
J. Virol. 80, 7775-7780
 |  Abstract »  |  Full Text »  |  PDF »

N-Glycans on Nipah Virus Fusion Protein Protect against Neutralization but Reduce Membrane Fusion and Viral Entry..

H. C. Aguilar, K. A. Matreyek, C. M. Filone, S. T. Hashimi, E. L. Levroney, O. A. Negrete, A. Bertolotti-Ciarlet, D. Y. Choi, I. McHardy, J. A. Fulcher, et al. (2006)
J. Virol. 80, 4878-4889
 |  Abstract »  |  Full Text »  |  PDF »

Membrane-Anchored Inhibitory Peptides Capture Human Immunodeficiency Virus Type 1 gp41 Conformations That Engage the Target Membrane prior to Fusion..

G. B. Melikyan, M. Egelhofer, and D. von Laer (2006)
J. Virol. 80, 3249-3258
 |  Abstract »  |  Full Text »  |  PDF »

A Mutation in the Human Immunodeficiency Virus Type 1 Gag Protein Destabilizes the Interaction of the Envelope Protein Subunits gp120 and gp41.

M. R. Davis, J. Jiang, J. Zhou, E. O. Freed, and C. Aiken (2006)
J. Virol. 80, 2405-2417
 |  Abstract »  |  Full Text »  |  PDF »

Nature of Nonfunctional Envelope Proteins on the Surface of Human Immunodeficiency Virus Type 1.

P. L. Moore, E. T. Crooks, L. Porter, P. Zhu, C. S. Cayanan, H. Grise, P. Corcoran, M. B. Zwick, M. Franti, L. Morris, et al. (2006)
J. Virol. 80, 2515-2528
 |  Abstract »  |  Full Text »  |  PDF »

TLR7/8 Triggering Exerts Opposing Effects in Acute versus Latent HIV Infection..

E. Schlaepfer, A. Audige, H. Joller, and R. F. Speck (2006)
J. Immunol. 176, 2888-2895
 |  Abstract »  |  Full Text »  |  PDF »

Structure of the Fab Fragment of F105, a Broadly Reactive Anti-Human Immunodeficiency Virus (HIV) Antibody That Recognizes the CD4 Binding Site of HIV Type 1 gp120.

R. A. Wilkinson, C. Piscitelli, M. Teintze, L. A. Cavacini, M. R. Posner, and C. M. Lawrence (2005)
J. Virol. 79, 13060-13069
 |  Abstract »  |  Full Text »  |  PDF »

Stoichiometry of Envelope Glycoprotein Trimers in the Entry of Human Immunodeficiency Virus Type 1.

X. Yang, S. Kurteva, X. Ren, S. Lee, and J. Sodroski (2005)
J. Virol. 79, 12132-12147
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Humoral Immune Responses following Vaccination with Envelope-Containing, Formaldehyde-Treated, Thermally Inactivated Human Immunodeficiency Virus Type 1.

B. Poon, J. T. Safrit, H. McClure, C. Kitchen, J. F. Hsu, V. Gudeman, C. Petropoulos, T. Wrin, I. S. Y. Chen, and K. Grovit-Ferbas (2005)
J. Virol. 79, 4927-4935
 |  Abstract »  |  Full Text »  |  PDF »

Construction of a Minimal HIV-1 Variant that Selectively Replicates in Leukemic Derived T-Cell Lines: Towards a New Virotherapy Approach.

R. E. Jeeninga, B. Jan, B. van der Linden, H. van den Berg, and B. Berkhout (2005)
Cancer Res. 65, 3347-3355
 |  Abstract »  |  Full Text »  |  PDF »

Receptor-Induced Conformational Changes in the SU Subunit of the Avian Sarcoma/Leukosis Virus A Envelope Protein: Implications for Fusion Activation.

S. E. Delos, J. A. Godby, and J. M. White (2005)
J. Virol. 79, 3488-3499
 |  Abstract »  |  Full Text »  |  PDF »

Stoichiometry of Antibody Neutralization of Human Immunodeficiency Virus Type 1.

X. Yang, S. Kurteva, S. Lee, and J. Sodroski (2005)
J. Virol. 79, 3500-3508
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Characterization of a Soluble, Active Form of the Jaagsiekte Sheep Retrovirus Receptor, Hyal2.

V. Vigdorovich, R. K. Strong, and A. D. Miller (2005)
J. Virol. 79, 79-86
 |  Abstract »  |  Full Text »  |  PDF »

Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies.

J. M. Binley, T. Wrin, B. Korber, M. B. Zwick, M. Wang, C. Chappey, G. Stiegler, R. Kunert, S. Zolla-Pazner, H. Katinger, et al. (2004)
J. Virol. 78, 13232-13252
 |  Abstract »  |  Full Text »  |  PDF »

CpG Oligodeoxynucleotides Block Human Immunodeficiency Virus Type 1 Replication in Human Lymphoid Tissue Infected Ex Vivo.

E. Schlaepfer, A. Audige, B. von Beust, V. Manolova, M. Weber, H. Joller, M. F. Bachmann, T. M. Kundig, and R. F. Speck (2004)
J. Virol. 78, 12344-12354
 |  Abstract »  |  Full Text »  |  PDF »

Nef Stimulates Human Immunodeficiency Virus Type 1 Replication in Primary T Cells by Enhancing Virion-Associated gp120 Levels: Coreceptor-Dependent Requirement for Nef in Viral Replication.

C. A. Lundquist, J. Zhou, and C. Aiken (2004)
J. Virol. 78, 6287-6296
 |  Abstract »  |  Full Text »  |  PDF »

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins.

Z. Si, N. Madani, J. M. Cox, J. J. Chruma, J. C. Klein, A. Schon, N. Phan, L. Wang, A. C. Biorn, S. Cocklin, et al. (2004)
PNAS 101, 5036-5041
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Ectodomain of the gp41 Transmembrane Envelope Protein of Human Immunodeficiency Virus Type 1 in Late Steps of the Membrane Fusion Process.

S. Bar and M. Alizon (2004)
J. Virol. 78, 811-820
 |  Abstract »  |  Full Text »  |  PDF »

A Point Mutation in the Binding Subunit of a Retroviral Envelope Protein Arrests Virus Entry at Hemifusion.

T. Zavorotinskaya, Z. Qian, J. Franks, and L. M. Albritton (2004)
J. Virol. 78, 473-481
 |  Abstract »  |  Full Text »  |  PDF »

Covalently Linked Human Immunodeficiency Virus Type 1 gp120/gp41 Is Stably Anchored in Rhabdovirus Particles and Exposes Critical Neutralizing Epitopes.

P. M. McKenna, R. J. Pomerantz, B. Dietzschold, J. P. McGettigan, and M. J. Schnell (2003)
J. Virol. 77, 12782-12794
 |  Abstract »  |  Full Text »  |  PDF »

Polyclonal Immunoglobulin G from Patients Neutralizes Human Immunodeficiency Virus Type 1 Primary Isolates by Binding Free Virions, but without Interfering with an Initial CD4-Independent Attachment of the Virus to Primary Blood Mononuclear Cells.

R. Burrer, S. Haessig-Einius, A.-M. Aubertin, and C. Moog (2003)
J. Virol. 77, 11385-11397
 |  Abstract »  |  Full Text »  |  PDF »

Specific CD4 down-modulating compounds with potent anti-HIV activity.

K. Vermeire and D. Schols (2003)
J. Leukoc. Biol. 74, 667-675
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Mutation Q252R in Activating Membrane Fusion in the Murine Leukemia Virus Surface Envelope Protein.

C.-W. Lu and M. J. Roth (2003)
J. Virol. 77, 10841-10849
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Virulence Mediated by the Murine Coronavirus, Mouse Hepatitis Virus Strain JHM, Is Associated with a Glycine at Residue 310 of the Spike Glycoprotein.

E. Ontiveros, T. S. Kim, T. M. Gallagher, and S. Perlman (2003)
J. Virol. 77, 10260-10269
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Fusion by the SER Virus F Protein: a Low-pH-Dependent Paramyxovirus Entry Process.

S. Seth, A. Vincent, and R. W. Compans (2003)
J. Virol. 77, 6520-6527
 |  Abstract »  |  Full Text »  |  PDF »

APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro.

C. F. Pereira, J. T. M. L. Paridaen, M. van de Bovenkamp, J. Middel, J. Verhoef, and H. S. L. M. Nottet (2003)
J. Antimicrob. Chemother. 51, 1181-1189
 |  Abstract »  |  Full Text »  |  PDF »

Cytoplasmic Tail of Moloney Murine Leukemia Virus Envelope Protein Influences the Conformation of the Extracellular Domain: Implications for Mechanism of Action of the R Peptide.

H. C. Aguilar, W. F. Anderson, and P. M. Cannon (2002)
J. Virol. 77, 1281-1291
 |  Abstract »  |  Full Text »  |  PDF »

Concordant Modulation of Neutralization Resistance and High Infectivity of the Primary Human Immunodeficiency Virus Type 1 MN Strain and Definition of a Potential gp41 Binding Site in gp120.

M. Leavitt, E. J. Park, I. A. Sidorov, D. S. Dimitrov, and G. V. Quinnan Jr. (2002)
J. Virol. 77, 560-570
 |  Abstract »  |  Full Text »  |  PDF »

Occupancy and mechanism in antibody-mediated neutralization of animal viruses.

P. J. Klasse and Q. J. Sattentau (2002)
J. Gen. Virol. 83, 2091-2108
 |  Abstract »  |  Full Text »  |  PDF »

Cell surface receptors, virus entry and tropism of primate lentiviruses.

P. R. Clapham and A. McKnight (2002)
J. Gen. Virol. 83, 1809-1829
 |  Abstract »  |  Full Text »  |  PDF »

Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy.

X. Wei, J. M. Decker, H. Liu, Z. Zhang, R. B. Arani, J. M. Kilby, M. S. Saag, X. Wu, G. M. Shaw, and J. C. Kappes (2002)
Antimicrob. Agents Chemother. 46, 1896-1905
 |  Abstract »  |  Full Text »  |  PDF »

Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes.

M. Moulard, S. K. Phogat, Y. Shu, A. F. Labrijn, X. Xiao, J. M. Binley, M.-Y. Zhang, I. A. Sidorov, C. C. Broder, J. Robinson, et al. (2002)
PNAS 99, 6913-6918
 |  Abstract »  |  Full Text »  |  PDF »

Envelope Glycoprotein Incorporation, Not Shedding of Surface Envelope Glycoprotein (gp120/SU), Is the Primary Determinant of SU Content of Purified Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus.

E. Chertova, J. W. Bess Jr., B. J. Crise, R. C. Sowder II, T. M. Schaden, J. M. Hilburn, J. A. Hoxie, R. E. Benveniste, J. D. Lifson, L. E. Henderson, et al. (2002)
J. Virol. 76, 5315-5325
 |  Abstract »  |  Full Text »  |  PDF »

Mutations That Destabilize the gp41 Core Are Determinants for Stabilizing the Simian Immunodeficiency Virus-CPmac Envelope Glycoprotein Complex.

J. Liu, S. Wang, J. A. Hoxie, C. C. LaBranche, and M. Lu (2002)
J. Biol. Chem. 277, 12891-12900
 |  Abstract »  |  Full Text »  |  PDF »

Solid-Phase Proteoliposomes Containing Human Immunodeficiency Virus Envelope Glycoproteins.

C. Grundner, T. Mirzabekov, J. Sodroski, and R. Wyatt (2002)
J. Virol. 76, 3511-3521
 |  Abstract »  |  Full Text »  |  PDF »

Enhancing the Proteolytic Maturation of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins.

J. M. Binley, R. W. Sanders, A. Master, C. S. Cayanan, C. L. Wiley, L. Schiffner, B. Travis, S. Kuhmann, D. R. Burton, S.-L. Hu, et al. (2002)
J. Virol. 76, 2606-2616
 |  Abstract »  |  Full Text »  |  PDF »

Effector Function Activities of a Panel of Mutants of a Broadly Neutralizing Antibody against Human Immunodeficiency Virus Type 1.

M. Hezareh, A. J. Hessell, R. C. Jensen, J. G. J. van de Winkel, and P. W. H. I. Parren (2001)
J. Virol. 75, 12161-12168
 |  Abstract »  |  Full Text »  |  PDF »

Neutralization Synergy of Human Immunodeficiency Virus Type 1 Primary Isolates by Cocktails of Broadly Neutralizing Antibodies.

M. B. Zwick, M. Wang, P. Poignard, G. Stiegler, H. Katinger, D. R. Burton, and P. W. H. I. Parren (2001)
J. Virol. 75, 12198-12208
 |  Abstract »  |  Full Text »  |  PDF »

Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41.

M. B. Zwick, A. F. Labrijn, M. Wang, C. Spenlehauer, E. O. Saphire, J. M. Binley, J. P. Moore, G. Stiegler, H. Katinger, D. R. Burton, et al. (2001)
J. Virol. 75, 10892-10905
 |  Abstract »  |  Full Text »  |  PDF »

HIV-1 receptors and cell tropism.

P. R Clapham and A. McKnight (2001)
Br. Med. Bull. 58, 43-59
 |  Abstract »  |  Full Text »  |  PDF »

Structural Flexibility and Functional Valence of CD4-IgG2 (PRO 542): Potential for Cross-Linking Human Immunodeficiency Virus Type 1 Envelope Spikes.

P. Zhu, W. C. Olson, and K. H. Roux (2001)
J. Virol. 75, 6682-6686
 |  Abstract »  |  Full Text »

Replacement of the V3 Region of gp120 with SDF-1 Preserves the Infectivity of T-Cell Line-Tropic Human Immunodeficiency Virus Type 1.

A. Yonezawa, T. Hori, A. Takaori-Kondo, R. Morita, and T. Uchiyama (2001)
J. Virol. 75, 4258-4267
 |  Abstract »  |  Full Text »

Loss of a Single N-Linked Glycan Allows CD4-Independent Human Immunodeficiency Virus Type 1 Infection by Altering the Position of the gp120 V1/V2 Variable Loops.

P. Kolchinsky, E. Kiprilov, P. Bartley, R. Rubinstein, and J. Sodroski (2001)
J. Virol. 75, 3435-3443
 |  Abstract »  |  Full Text »

Antibody Binding and Neutralization of Primary and T-Cell Line-Adapted Isolates of Human Immunodeficiency Virus Type 1.

J. York, K. E. Follis, M. Trahey, P. N. Nyambi, S. Zolla-Pazner, and J. H. Nunberg (2001)
J. Virol. 75, 2741-2752
 |  Abstract »  |  Full Text »

Increased Neutralization Sensitivity of CD4-Independent Human Immunodeficiency Virus Variants.

P. Kolchinsky, E. Kiprilov, and J. Sodroski (2001)
J. Virol. 75, 2041-2050
 |  Abstract »  |  Full Text »

Evidence for a Stable Interaction of gp41 with Pr55Gag in Immature Human Immunodeficiency Virus Type 1 Particles.

D. J. Wyma, A. Kotov, and C. Aiken (2000)
J. Virol. 74, 9381-9387
 |  Abstract »  |  Full Text »

Sensitivity of Human Immunodeficiency Virus Type 1 to the Fusion Inhibitor T-20 Is Modulated by Coreceptor Specificity Defined by the V3 Loop of gp120.

C. A. Derdeyn, J. M. Decker, J. N. Sfakianos, X. Wu, W. A. O'Brien, L. Ratner, J. C. Kappes, G. M. Shaw, and E. Hunter (2000)
J. Virol. 74, 8358-8367
 |  Abstract »  |  Full Text »

Energetics of the HIV gp120-CD4 binding reaction.

D. G. Myszka, R. W. Sweet, P. Hensley, M. Brigham-Burke, P. D. Kwong, W. A. Hendrickson, R. Wyatt, J. Sodroski, and M. L. Doyle (2000)
PNAS 97, 9026-9031
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Binding of Antibodies to Neutralization Epitopes following Thermal and Chemical Inactivation of Human Immunodeficiency Virus Type 1.

K. Grovit-Ferbas, J. F. Hsu, J. Ferbas, V. Gudeman, and I. S. Y. Chen (2000)
J. Virol. 74, 5802-5809
 |  Abstract »  |  Full Text »

Variable-Loop-Deleted Variants of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Can Be Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits.

R. W. Sanders, L. Schiffner, A. Master, F. Kajumo, Y. Guo, T. Dragic, J. P. Moore, and J. M. Binley (2000)
J. Virol. 74, 5091-5100
 |  Abstract »  |  Full Text »

Functional Differences between the Long Terminal Repeat Transcriptional Promoters of Human Immunodeficiency Virus Type 1 Subtypes A through G.

R. E. Jeeninga, M. Hoogenkamp, M. Armand-Ugon, M. de Baar, K. Verhoef, and B. Berkhout (2000)
J. Virol. 74, 3740-3751
 |  Abstract »  |  Full Text »

Sensitivity to a Nonpeptidic Compound (RPR103611) Blocking Human Immunodeficiency Virus Type 1 Env-Mediated Fusion Depends on Sequence and Accessibility of the gp41 Loop Region.

B. Labrosse, C. Treboute, and M. Alizon (2000)
J. Virol. 74, 2142-2150
 |  Abstract »  |  Full Text »

Selective Interactions of Polyanions with Basic Surfaces on Human Immunodeficiency Virus Type 1 gp120.

M. Moulard, H. Lortat-Jacob, I. Mondor, G. Roca, R. Wyatt, J. Sodroski, L. Zhao, W. Olson, P. D. Kwong, and Q. J. Sattentau (2000)
J. Virol. 74, 1948-1960
 |  Abstract »  |  Full Text »

A Recombinant Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Complex Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits Is an Antigenic Mimic of the Trimeric Virion-Associated Structure.

J. M. Binley, R. W. Sanders, B. Clas, N. Schuelke, A. Master, Y. Guo, F. Kajumo, D. J. Anselma, P. J. Maddon, W. C. Olson, et al. (2000)
J. Virol. 74, 627-643
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A Cell Line-Based Neutralization Assay for Primary Human Immunodeficiency Virus Type 1 Isolates That Use either the CCR5 or the CXCR4 Coreceptor.

A. Trkola, J. Matthews, C. Gordon, T. Ketas, and J. P. Moore (1999)
J. Virol. 73, 8966-8974
 |  Abstract »  |  Full Text »  |  PDF »

Adaptation of a CCR5-Using, Primary Human Immunodeficiency Virus Type 1 Isolate for CD4-Independent Replication.

P. Kolchinsky, T. Mirzabekov, M. Farzan, E. Kiprilov, M. Cayabyab, L. J. Mooney, H. Choe, and J. Sodroski (1999)
J. Virol. 73, 8120-8126
 |  Abstract »  |  Full Text »  |  PDF »

CD4-Chemokine Receptor Hybrids in Human Immunodeficiency Virus Type 1 Infection.

P. J. Klasse, M. M. Rosenkilde, N. Signoret, A. Pelchen-Matthews, T. W. Schwartz, and M. Marsh (1999)
J. Virol. 73, 7453-7466
 |  Abstract »  |  Full Text »

Effects of Soluble CD4 on Simian Immunodeficiency Virus Infection of CD4-Positive and CD4-Negative Cells.

D. Schenten, L. Marcon, G. B. Karlsson, C. Parolin, T. Kodama, N. Gerard, and J. Sodroski (1999)
J. Virol. 73, 5373-5380
 |  Abstract »  |  Full Text »

Variable Constraints on the Principal Immunodominant Domain of the Transmembrane Glycoprotein of Human Immunodeficiency Virus Type 1.

R. Merat, H. Raoul, T. Leste-Lasserre, P. Sonigo, and G. Pancino (1999)
J. Virol. 73, 5698-5706
 |  Abstract »  |  Full Text »

Production and Characterization of a Soluble, Active Form of Tva, the Subgroup A Avian Sarcoma and Leukosis Virus Receptor.

J. W. Balliet, J. Berson, C. M. D'Cruz, J. Huang, J. Crane, J. M. Gilbert, and P. Bates (1999)
J. Virol. 73, 3054-3061
 |  Abstract »  |  Full Text »

Substitutions in the Receptor-Binding Domain of the Avian Sarcoma and Leukosis Virus Envelope Uncouple Receptor-Triggered Structural Rearrangements in the Surface and Transmembrane Subunits.

R. Damico, L. Rong, and P. Bates (1999)
J. Virol. 73, 3087-3094
 |  Abstract »  |  Full Text »

Detection of Human Immunodeficiency Virus Type 1 Nucleocapsid Protein p7 In Vitro and In Vivo.

M. P. de Baar, K. H. M. van der Horn, J. Goudsmit, A. de Ronde, and F. de Wolf (1999)
J. Clin. Microbiol. 37, 63-67
 |  Abstract »  |  Full Text »

A Hairpin Structure in the R Region of the Human Immunodeficiency Virus Type 1 RNA Genome Is Instrumental in Polyadenylation Site Selection.

A. T. Das, B. Klaver, and B. Berkhout (1999)
J. Virol. 73, 81-91
 |  Abstract »  |  Full Text »  |  PDF »

Mutational Analysis of Residues in the Coiled-Coil Domain of Human Immunodeficiency Virus Type 1 Transmembrane Protein gp41.

Y. Weng and C. D. Weiss (1998)
J. Virol. 72, 9676-9682
 |  Abstract »  |  Full Text »  |  PDF »

Determinants of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Activation by Soluble CD4 and Monoclonal Antibodies.

N. Sullivan, Y. Sun, J. Binley, J. Lee, C. F. Barbas III, P. W. H. I. Parren, D. R. Burton, and J. Sodroski (1998)
J. Virol. 72, 6332-6338
 |  Abstract »  |  Full Text »  |  PDF »

CD4-Induced Conformational Changes in the Human Immunodeficiency Virus Type 1 gp120 Glycoprotein: Consequences for Virus Entry and Neutralization.

N. Sullivan, Y. Sun, Q. Sattentau, M. Thali, D. Wu, G. Denisova, J. Gershoni, J. Robinson, J. Moore, and J. Sodroski (1998)
J. Virol. 72, 4694-4703
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Type 1 Attachment to HeLa CD4 Cells Is CD4 Independent and gp120 Dependent and Requires Cell Surface Heparans.

I. Mondor, S. Ugolini, and Q. J. Sattentau (1998)
J. Virol. 72, 3623-3634
 |  Abstract »  |  Full Text »  |  PDF »

HIV-1 Directly Kills CD4+ T Cells by a Fas-independent Mechanism.

R. T. Gandhi, B. K. Chen, S. E. Straus, J. K. Dale, M. J. Lenardo, and D. Baltimore (1998)
J. Exp. Med. 187, 1113-1122
 |  Abstract »  |  Full Text »  |  PDF »

Determinants of Human Immunodeficiency Virus Type 1 Resistance to gp41-Derived Inhibitory Peptides.

L. T. Rimsky, D. C. Shugars, and T. J. Matthews (1998)
J. Virol. 72, 986-993
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular and Surface Expression of the HIV-1 Coreceptor CXCR4/Fusin on Various Leukocyte Subsets: Rapid Internalization and Recycling Upon Activation.

R. Forster, E. Kremmer, A. Schubel, D. Breitfeld, A. Kleinschmidt, C. Nerl, G. Bernhardt, and M. Lipp (1998)
J. Immunol. 160, 1522-1531
 |  Abstract »  |  Full Text »  |  PDF »

Atomic structure of a thermostable subdomain of HIV-1 gp41.

K. Tan, J.-h. Liu, J.-h. Wang, S. Shen, and M. Lu (1997)
PNAS 94, 12303-12308
 |  Abstract »  |  Full Text »  |  PDF »

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4.

N. Signoret, J. Oldridge, A. Pelchen-Matthews, P. J. Klasse, T. Tran, L. F. Brass, M. M. Rosenkilde, T. W. Schwartz, W. Holmes, W. Dallas, et al. (1997)
J. Cell Biol. 139, 651-664
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Virus Attachment to CD4+ Target Cells Is a Major Mechanism of T Cell Line-adapted HIV-1 Neutralization.

S. Ugolini, I. Mondor, P. W.H.I. Parren, D. R. Burton, S. A. Tilley, P. J. Klasse, and Q. J. Sattentau (1997)
J. Exp. Med. 186, 1287-1298
 |  Abstract »  |  Full Text »  |  PDF »

Antibodies to several conformation-dependent epitopes of gp120/gp41 inhibit CCR-5-dependent cell-to-cell fusion mediated by the native envelope glycoprotein of a primary macrophage-tropic HIV-1 isolate.

F. C. Verrier, P. Charneau, R. Altmeyer, S. Laurent, A. M. Borman, and M. Girard (1997)
PNAS 94, 9326-9331
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins in Virus Infection.

E. O. Freed and M. A. Martin (1995)
J. Biol. Chem. 270, 23883-23886
 |  Full Text »  |  PDF »

Present status and future prospects for HIV therapies.

M. Johnston and D. Hoth (1993)
Science 260, 1286-1293
 |  Abstract »  |  PDF »

High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR.

M Piatak Jr, M. Saag, L. Yang, S. Clark, J. Kappes, K. Luk, B. Hahn, G. Shaw, and J. Lifson (1993)
Science 259, 1749-1754
 |  Abstract »  |  PDF »

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