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Science 16 November 1990:
Vol. 250. no. 4983, pp. 1002 - 1004
DOI: 10.1126/science.250.4983.1002
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Articles

Salicylic Acid: A Likely Endogenous Signal in the Resistance Response of Tobacco to Viral Infection

Jocelyn Malamy 1, John P. Carr 1, Daniel F. Klessig 1, and Ilya Raskin 2

1 Waksman Institute, Rutgers, The State University of New Jersey, Piscataway, NJ 08855
2 Center for Agricultural Molecular Biology, Rutgers, The State University of New Jersey, Cook College, Post Office Box 231, New Brunswick, NJ 08903

Some cultivars of tobacco are resistant to tobacco mosaic virus (TMV) and synthesize pathogenesis-related (PR) proteins upon infection. In a search for the signal or signals that induce resistance or PR genes, it was found that the endogenous salicylic acid levels in resistant, but not susceptible, cultivars increased at least 20-fold in infected leaves and 5-fold in uninfected leaves after TMV inoculation. Induction of PRl genes paralleled the rise in salicylic acid levels. Since earlier work has demonstrated that treatment with exogenous salicylic acid induces PR genes and resistance, these findings suggest that salicylic acid functions as the natural transduction signal.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)