Science 2 November 1990: Vol. 250. no. 4981, pp. 646 - 651 DOI: 10.1126/science.2237415

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Articles

Role of a Putative gp41 Dimerization Domain in Human Immunodeficiency Virus Type 1 Membrane Fusion.

J. Liu, Y. Deng, Q. Li, A. K. Dey, J. P. Moore, and M. Lu (2010)
J. Virol. 84, 201-209
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure of a "Nonfoldable" Insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY.

M. Liu, Z.-l. Wan, Y.-C. Chu, H. Aladdin, B. Klaproth, M. Choquette, Q.-x. Hua, R. B. Mackin, J. S. Rao, P. De Meyts, et al. (2009)
J. Biol. Chem. 284, 35259-35272
 |  Abstract »  |  Full Text »  |  PDF »

A Conserved {alpha}-Helix Essential for a Type VI Secretion-Like System of Francisella tularensis.

J. E. Broms, M. Lavander, and A. Sjostedt (2009)
J. Bacteriol. 191, 2431-2446
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the IS6-AID Linker Affects Voltage-gated Calcium Channel Inactivation and Facilitation.

F. Findeisen and D. L. Minor Jr. (2009)
J. Gen. Physiol. 133, 327-343
 |  Abstract »  |  Full Text »  |  PDF »

Voltage- and [ATP]-dependent Gating of the P2X2 ATP Receptor Channel.

Y. Fujiwara, B. Keceli, K. Nakajo, and Y. Kubo (2009)
J. Gen. Physiol. 133, 93-109
 |  Abstract »  |  Full Text »  |  PDF »

Kv Channel Gating Requires a Compatible S4-S5 Linker and Bottom Part of S6, Constrained by Non-interacting Residues.

A. J. Labro, A. L. Raes, A. Grottesi, D. Van Hoorick, M. S.P. Sansom, and D. J. Snyders (2008)
J. Gen. Physiol. 132, 667-680
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Gating Brake in the I-II Loop of Cav3.2 T-type Ca2+ Channels.

I. I. Arias-Olguin, I. Vitko, M. Fortuna, J. P. Baumgart, S. Sokolova, I. A. Shumilin, A. Van Deusen, M. Soriano-Garcia, J. C. Gomora, and E. Perez-Reyes (2008)
J. Biol. Chem. 283, 8136-8144
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of Gly721 Alters DNA Topoisomerase I Active Site Architecture and Sensitivity to Camptothecin.

M. van der Merwe and M.-A. Bjornsti (2008)
J. Biol. Chem. 283, 3305-3315
 |  Abstract »  |  Full Text »  |  PDF »

Duplication of Accelerated Evolution and Growth Hormone Gene in Passerine Birds.

T. Yuri, R. T. Kimball, E. L. Braun, and M. J. Braun (2008)
Mol. Biol. Evol. 25, 352-361
 |  Abstract »  |  Full Text »  |  PDF »

Role of the S6 C-terminus in KCNQ1 channel gating.

I. R. Boulet, A. J. Labro, A. L. Raes, and D. J. Snyders (2007)
J. Physiol. 585, 325-337
 |  Abstract »  |  Full Text »  |  PDF »

The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.

K. Huang, S. J. Chan, Q.-x. Hua, Y.-C. Chu, R.-y. Wang, B. Klaproth, W. Jia, J. Whittaker, P. De Meyts, S. H. Nakagawa, et al. (2007)
J. Biol. Chem. 282, 35337-35349
 |  Abstract »  |  Full Text »  |  PDF »

Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus.

J. J. Dwyer, K. L. Wilson, D. K. Davison, S. A. Freel, J. E. Seedorff, S. A. Wring, N. A. Tvermoes, T. J. Matthews, M. L. Greenberg, and M. K. Delmedico (2007)
PNAS 104, 12772-12777
 |  Abstract »  |  Full Text »  |  PDF »

Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50/Rta Lytic Switch Protein Functions as a Tetramer.

W. Bu, K. D. Carroll, D. Palmeri, and D. M. Lukac (2007)
J. Virol. 81, 5788-5806
 |  Abstract »  |  Full Text »  |  PDF »

Clade-Specific Differences between Human Immunodeficiency Virus Type 1 Clades B and C: Diversity and Correlations in C3-V4 Regions of gp120.

S. Gnanakaran, D. Lang, M. Daniels, T. Bhattacharya, C. A. Derdeyn, and B. Korber (2007)
J. Virol. 81, 4886-4891
 |  Abstract »  |  Full Text »  |  PDF »

Conformational entropy of alanine versus glycine in protein denatured states.

K. A. Scott, D. O. V. Alonso, S. Sato, A. R. Fersht, and V. Daggett (2007)
PNAS 104, 2661-2666
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Characterization of Crustacean Visual Pigments and the Evolution of Pancrustacean Opsins.

M. L. Porter, T. W. Cronin, D. A. McClellan, and K. A. Crandall (2007)
Mol. Biol. Evol. 24, 253-268
 |  Abstract »  |  Full Text »  |  PDF »

The Role of the GX9GX3G Motif in the Gating of High Voltage-activated Ca2+ Channels.

A. Raybaud, Y. Dodier, P. Bissonnette, M. Simoes, D. G. Bichet, R. Sauve, and L. Parent (2006)
J. Biol. Chem. 281, 39424-39436
 |  Abstract »  |  Full Text »  |  PDF »

Trafficking and Assembly of the Cold-sensitive TRPM8 Channel.

I. Erler, D. M. M. Al-Ansary, U. Wissenbach, T. F. J. Wagner, V. Flockerzi, and B. A. Niemeyer (2006)
J. Biol. Chem. 281, 38396-38404
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Amino Acid Replacements on the Structural Stability of Fish Myoglobin.

N. Ueki and Y. Ochiai (2006)
J. Biochem. 140, 649-656
 |  Abstract »  |  Full Text »  |  PDF »

A seven-helix coiled coil.

J. Liu, Q. Zheng, Y. Deng, C.-S. Cheng, N. R. Kallenbach, and M. Lu (2006)
PNAS 103, 15457-15462
 |  Abstract »  |  Full Text »  |  PDF »

Toward the Active Conformation of Insulin: STEREOSPECIFIC MODULATION OF A STRUCTURAL SWITCH IN THE B CHAIN.

Q.-x. Hua, S. Nakagawa, S.-Q. Hu, W. Jia, S. Wang, and M. A. Weiss (2006)
J. Biol. Chem. 281, 24900-24909
 |  Abstract »  |  Full Text »  |  PDF »

Cross-Species Annotation of Basic Leucine Zipper Factor Interactions: Insight into the Evolution of Closed Interaction Networks.

C. D. Deppmann, R. S. Alvania, and E. J. Taparowsky (2006)
Mol. Biol. Evol. 23, 1480-1492
 |  Abstract »  |  Full Text »  |  PDF »

Semirational design of Jun-Fos coiled coils with increased affinity: Universal implications for leucine zipper prediction and design.

J. M. Mason, M. A. Schmitz, K. M. Muller, and K. M. Arndt (2006)
PNAS 103, 8989-8994
 |  Abstract »  |  Full Text »  |  PDF »

Generation and analysis of proline mutants in protein G.

E. J. Choi and S. L. Mayo (2006)
Protein Eng. Des. Sel. 19, 285-289
 |  Abstract »  |  Full Text »  |  PDF »

Common and Variable Contributions of Fis Residues to High-Affinity Binding at Different DNA Sequences.

L. S. Feldman-Cohen, Y. Shao, D. Meinhold, C. Miller, W. Colon, and R. Osuna (2006)
J. Bacteriol. 188, 2081-2095
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of GADD45 Family Members to Cell Death Suppression by Cellular Bcl-xL and Cytomegalovirus vMIA.

G. B. Smith and E. S. Mocarski (2005)
J. Virol. 79, 14923-14932
 |  Abstract »  |  Full Text »  |  PDF »

RNA-protein recognition: Single-residue ultrafast dynamical control of structural specificity and function.

T. Xia, C. Wan, R. W. Roberts, and A. H. Zewail (2005)
PNAS 102, 13013-13018
 |  Abstract »  |  Full Text »  |  PDF »

Investigating the Putative Glycine Hinge in Shaker Potassium Channel.

S. Ding, L. Ingleby, C. A. Ahern, and R. Horn (2005)
J. Gen. Physiol. 126, 213-226
 |  Abstract »  |  Full Text »  |  PDF »

The Structure of a pH-Sensing Mycobacterial Adenylyl Cyclase Holoenzyme.

I. Tews, F. Findeisen, I. Sinning, A. Schultz, J. E. Schultz, and J. U. Linder (2005)
Science 308, 1020-1023
 |  Abstract »  |  Full Text »  |  PDF »

Prediction of Collagen Stability from Amino Acid Sequence.

A. V. Persikov, J. A. M. Ramshaw, and B. Brodsky (2005)
J. Biol. Chem. 280, 19343-19349
 |  Abstract »  |  Full Text »  |  PDF »

Contributions of Disulfide Bonds in a Nested Pattern to the Structure, Stability, and Biological Functions of Endostatin.

H. Zhou, W. Wang, and Y. Luo (2005)
J. Biol. Chem. 280, 11303-11312
 |  Abstract »  |  Full Text »  |  PDF »

Enthalpy of helix-coil transition: Missing link in rationalizing the thermodynamics of helix-forming propensities of the amino acid residues.

J. M. Richardson, M. M. Lopez, and G. I. Makhatadze (2005)
PNAS 102, 1413-1418
 |  Abstract »  |  Full Text »  |  PDF »

Negatively charged purification tags for selective anion-exchange recovery.

M. Hedhammar, T. Graslund, M. Uhlen, and S. Hober (2004)
Protein Eng. Des. Sel. 17, 779-786
 |  Abstract »  |  Full Text »  |  PDF »

Stabilizing and Destabilizing Clusters in the Hydrophobic Core of Long Two-stranded {alpha}-Helical Coiled-coils.

S. C. Kwok and R. S. Hodges (2004)
J. Biol. Chem. 279, 21576-21588
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Motif in Geminivirus Replication Proteins Interacts with the Plant Retinoblastoma-Related Protein.

G. Arguello-Astorga, L. Lopez-Ochoa, L.-J. Kong, B. M. Orozco, S. B. Settlage, and L. Hanley-Bowdoin (2004)
J. Virol. 78, 4817-4826
 |  Abstract »  |  Full Text »  |  PDF »

Gating of Shaker-type Channels Requires the Flexibility of S6 Caused by Prolines.

A. J. Labro, A. L. Raes, I. Bellens, N. Ottschytsch, and D. J. Snyders (2003)
J. Biol. Chem. 278, 50724-50731
 |  Abstract »  |  Full Text »  |  PDF »

The role of intercalating residues in chromosomal high-mobility-group protein DNA binding, bending and specificity.

J. Klass, F. V. Murphy IV, S. Fouts, M. Serenil, A. Changela, J. Siple, and M. E. A. Churchill (2003)
Nucleic Acids Res. 31, 2852-2864
 |  Abstract »  |  Full Text »  |  PDF »

Generation of Highly Selective VPAC2 Receptor Agonists by High Throughput Mutagenesis of Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Peptide.

S. L. Yung, F. Dela Cruz, S. Hamren, J. Zhu, M. Tsutsumi, J. W. Bloom, M. Caudle, S. Roczniak, T. Todd, L. Lemoine, et al. (2003)
J. Biol. Chem. 278, 10273-10281
 |  Abstract »  |  Full Text »  |  PDF »

Inactivation of BK Channels by the NH2 Terminus of the {beta}2 Auxiliary Subunit: An Essential Role of a Terminal Peptide Segment of Three Hydrophobic Residues.

X.-M. Xia, J.P. Ding, and C. J. Lingle (2003)
J. Gen. Physiol. 121, 125-148
 |  Abstract »  |  Full Text »  |  PDF »

Short constrained peptides that inhibit HIV-1 entry.

S. K. Sia, P. A. Carr, A. G. Cochran, V. N. Malashkevich, and P. S. Kim (2002)
PNAS 99, 14664-14669
 |  Abstract »  |  Full Text »  |  PDF »

Salmonid viral haemorrhagic septicaemia virus: fusion-related enhancement of virus infectivity by peptides derived from viral glycoprotein G or a combinatorial library.

V. Mas, L. Perez, J. A. Encinar, M. T. Pastor, A. Rocha, E. Perez-Paya, A. Ferrer-Montiel, J. M. Gonzalez Ros, A. Estepa, and J. M. Coll (2002)
J. Gen. Virol. 83, 2671-2681
 |  Abstract »  |  Full Text »  |  PDF »

Sex-specific Gene Regulation. THE DOUBLESEX DM MOTIF IS A BIPARTITE DNA-BINDING DOMAIN.

U. Narendra, L. Zhu, B. Li, J. Wilken, and M. A. Weiss (2002)
J. Biol. Chem. 277, 43463-43473
 |  Abstract »  |  Full Text »  |  PDF »

Designing Heterodimeric Two-stranded alpha -Helical Coiled-coils. EFFECTS OF HYDROPHOBICITY AND alpha -HELICAL PROPENSITY ON PROTEIN FOLDING, STABILITY, AND SPECIFICITY.

J. R. Litowski and R. S. Hodges (2002)
J. Biol. Chem. 277, 37272-37279
 |  Abstract »  |  Full Text »  |  PDF »

Structural consequences of replacement of an {alpha}-helical Pro residue in Escherichia coli thioredoxin.

Rudresh, R. Jain, V. Dani, A. Mitra, S. Srivastava, S. P. Sarma, R. Varadarajan, and S. Ramakumar (2002)
Protein Eng. Des. Sel. 15, 627-633
 |  Abstract »  |  Full Text »  |  PDF »

Photo-control of peptide helix content by an azobenzene cross-linker: steric interactions with underlying residues are not critical.

J. R. Kumita, D. G. Flint, O. S. Smart, and G.A. Woolley (2002)
Protein Eng. Des. Sel. 15, 561-569
 |  Abstract »  |  Full Text »  |  PDF »

Design, Synthesis and Pharmacological Evaluation of 5-Hydroxytryptamine1a Receptor Ligands to Explore the Three-Dimensional Structure of the Receptor.

M. L. Lopez-Rodriguez, B. Vicente, X. Deupi, S. Barrondo, M. Olivella, M. J. Morcillo, B. Behamu, J. A. Ballesteros, J. Salles, and L. Pardo (2002)
Mol. Pharmacol. 62, 15-21
 |  Abstract »  |  Full Text »  |  PDF »

Scanning the Intracellular S6 Activation Gate in the Shaker K+ Channel.

D. H. Hackos, T.-H. Chang, and K. J. Swartz (2002)
J. Gen. Physiol. 119, 521-531
 |  Abstract »  |  Full Text »  |  PDF »

The Critical Role of Transmembrane Prolines in Human Prostacyclin Receptor Activation.

J. Stitham, K. A. Martin, and J. Hwa (2002)
Mol. Pharmacol. 61, 1202-1210
 |  Abstract »  |  Full Text »  |  PDF »

A Designed System for Assessing How Sequence Affects alpha to beta Conformational Transitions in Proteins.

B. Ciani, E. G. Hutchinson, R. B. Sessions, and D. N. Woolfson (2002)
J. Biol. Chem. 277, 10150-10155
 |  Abstract »  |  Full Text »  |  PDF »

Side-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coils.

A. E. Keating, V. N. Malashkevich, B. Tidor, and P. S. Kim (2001)
PNAS 98, 14825-14830
 |  Abstract »  |  Full Text »  |  PDF »

Amino Acid Substitutions of Coiled-Coil Protein Tpr Abrogate Anchorage to the Nuclear Pore Complex but Not Parallel, In-Register Homodimerization.

M. E. Hase, N. V. Kuznetsov, and V. C. Cordes (2001)
Mol. Biol. Cell 12, 2433-2452
 |  Abstract »  |  Full Text »  |  PDF »

Helical Structure of the Cooh Terminus of S3 and Its Contribution to the Gating Modifier Toxin Receptor in Voltage-Gated Ion Channels.

Y. Li-Smerin and K. J. Swartz (2001)
J. Gen. Physiol. 117, 205-218
 |  Abstract »  |  Full Text »  |  PDF »

Design of three-dimensional domain-swapped dimers and fibrous oligomers.

N. L. Ogihara, G. Ghirlanda, J. W. Bryson, M. Gingery, W. F. DeGrado, and D. Eisenberg (2001)
PNAS 98, 1404-1409
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: A computationally directed screen identifying interacting coiled coils from Saccharomyces cerevisiae.

J. R. S. Newman, E. Wolf, and P. S. Kim (2000)
PNAS 97, 13203-13208
 |  Abstract »  |  Full Text »  |  PDF »

Variation in residual PITX2 activity underlies the phenotypic spectrum of anterior segment developmental disorders.

K. Kozlowski and M. A. Walter (2000)
Hum. Mol. Genet. 9, 2131-2139
 |  Abstract »  |  Full Text »  |  PDF »

Distal Recognition Site for Classical Pathway Convertase Located in the C345C/Netrin Module of Complement Component C5.

A. Sandoval, R. Ai, J. M. Ostresh, and R. T. Ogata (2000)
J. Immunol. 165, 1066-1073
 |  Abstract »  |  Full Text »  |  PDF »

A Structural Requirement for Activation of Skeletal Ryanodine Receptors by Peptides of the Dihydropyridine Receptor II-III Loop.

M. G. Casarotto, F. Gibson, S. M. Pace, S. M. Curtis, M. Mulcair, and A. F. Dulhunty (2000)
J. Biol. Chem. 275, 11631-11637
 |  Abstract »  |  Full Text »  |  PDF »

Photo-control of helix content in a short peptide.

J. R. Kumita, O. S. Smart, and G. A. Woolley (2000)
PNAS 97, 3803-3808
 |  Abstract »  |  Full Text »  |  PDF »

Lysozyme among the Lilliputians.

G. D. Rose (2000)
PNAS 97, 526-528
 |  Full Text »  |  PDF »

Amino Acid Substitutions within the Leucine Zipper Domain of the Murine Coronavirus Spike Protein Cause Defects in Oligomerization and the Ability To Induce Cell-to-Cell Fusion.

Z. Luo, A. M. Matthews, and S. R. Weiss (1999)
J. Virol. 73, 8152-8159
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Thermal Stabilizing Interactions in Mesophilic and Thermophilic Adenylate Kinases from the Genus Methanococcus.

P. J. Haney, M. Stees, and J. Konisky (1999)
J. Biol. Chem. 274, 28453-28458
 |  Abstract »  |  Full Text »  |  PDF »

Intrinsic beta -sheet propensities result from van der Waals interactions between side chains and the local backbone.

A. G. Street and S. L. Mayo (1999)
PNAS 96, 9074-9076
 |  Abstract »  |  Full Text »  |  PDF »

Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding.

M. Sagermann, W. A. Baase, and B. W. Matthews (1999)
PNAS 96, 6078-6083
 |  Abstract »  |  Full Text »  |  PDF »

High-Resolution Protein Design with Backbone Freedom.

P. B. Harbury, J. J. Plecs, B. Tidor, T. Alber, and P. S. Kim (1998)
Science 282, 1462-1467
 |  Abstract »  |  Full Text »

A transcriptional activating region with two contrasting modes of protein interaction.

A. Z. Ansari, R. J. Reece, and M. Ptashne (1998)
PNAS 95, 13543-13548
 |  Abstract »  |  Full Text »  |  PDF »

Uncoupling Hydrophobicity and Helicity in Transmembrane Segments. alpha -HELICAL PROPENSITIES OF THE AMINO ACIDS IN NON-POLAR ENVIRONMENTS.

L.-P. Liu and C. M. Deber (1998)
J. Biol. Chem. 273, 23645-23648
 |  Abstract »  |  Full Text »  |  PDF »

Specific Single or Double Proline Substitutions in the "Spring-loaded" Coiled-Coil Region of the Influenza Hemagglutinin Impair or Abolish Membrane Fusion Activity.

H. Qiao, S. L. Pelletier, L. Hoffman, J. Hacker, R. T. Armstrong, and J. M. White (1998)
J. Cell Biol. 141, 1335-1347
 |  Abstract »  |  Full Text »  |  PDF »

Structure-based prediction of the stability of transmembrane helix-helix interactions: The sequence dependence of glycophorin A dimerization.

K. R. MacKenzie and D. M. Engelman (1998)
PNAS 95, 3583-3590
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Determinants of Na+ Channel Function in the Extracellular Domain of the beta 1 Subunit.

K. A. McCormick, L. L. Isom, D. Ragsdale, D. Smith, T. Scheuer, and W. A. Catterall (1998)
J. Biol. Chem. 273, 3954-3962
 |  Abstract »  |  Full Text »  |  PDF »

Positional Preferences of Ionizable Residues in Gly-X-Y Triplets of the Collagen Triple-helix.

V. C. Chan, J. A. M. Ramshaw, A. Kirkpatrick, K. Beck, and B. Brodsky (1997)
J. Biol. Chem. 272, 31441-31446
 |  Abstract »  |  Full Text »  |  PDF »

Gly-Pro-Arg Confers Stability Similar to Gly-Pro-Hyp in the Collagen Triple-helix of Host-Guest Peptides.

W. Yang, V. C. Chan, A. Kirkpatrick, J. A. M. Ramshaw, and B. Brodsky (1997)
J. Biol. Chem. 272, 28837-28840
 |  Abstract »  |  Full Text »  |  PDF »

Helix is a helix is a helix?.

L. Regan (1997)
PNAS 94, 2796-2797
 |  Full Text »  |  PDF »

A direct comparison of helix propensity in proteins and peptides.

J. K. Myers, C. N. Pace, and J. M. Scholtz (1997)
PNAS 94, 2833-2837
 |  Abstract »  |  Full Text »  |  PDF »

Protein Design: The Choice of de Novo Sequences.

J. R. Beasley and M. H. Hecht (1997)
J. Biol. Chem. 272, 2031-2034
 |  Full Text »  |  PDF »

Local Interactions in Protein Folding: Lessons from the alpha -Helix.

R. Aurora, T. P. Creamer, R. Srinivasan, and G. D. Rose (1997)
J. Biol. Chem. 272, 1413-1416
 |  Full Text »  |  PDF »

Cytoplasmic Localization of Mitogen-activated Protein Kinase Kinase Directed by Its NH2-terminal, Leucine-rich Short Amino Acid Sequence, Which Acts as a Nuclear Export Signal.

M. Fukuda, I. Gotoh, Y. Gotoh, and E. Nishida (1996)
J. Biol. Chem. 271, 20024-20028
 |  Abstract »  |  Full Text »  |  PDF »

Mass Spectrometric Identification of Leucine Zipper-like Homodimer Complexes of the Autoantigen L7.

S. Witte, F. Neumann, U. Krawinkel, and M. Przybylski (1996)
J. Biol. Chem. 271, 18171-18175
 |  Abstract »  |  Full Text »  |  PDF »

Chimeras of alpha(1)-Adrenergic Receptor Subtypes Identify Critical Residues That Modulate Active State Isomerization.

J. Hwa, R. M. Graham, and D. M. Perez (1996)
J. Biol. Chem. 271, 7956-7964
 |  Abstract »  |  Full Text »  |  PDF »

Functionalized Protein-like Structures from Conformationally Defined Synthetic Combinatorial Libraries.

E. Pérez-Payá, R. A. Houghten, and S. E. Blondelle (1996)
J. Biol. Chem. 271, 4120-4126
 |  Abstract »  |  Full Text »  |  PDF »

Structure-Activity Relationship of the Leucine-based Sorting Motifs in the Cytosolic Tail of the Major Histocompatibility Complex-associated Invariant Chain.

A. Motta, B.řr. Bremnes, M. A. C. Morelli, R. W. Frank, G. Saviano, and O. Bakke (1995)
J. Biol. Chem. 270, 27165-27171
 |  Abstract »  |  Full Text »  |  PDF »

Protein Design: A Hierarchic Approach.

J. W. Bryson, S. F. Betz, H. S. Lu, D. J. Suich, H. X. Zhou, K. T. O'Neil, and W. F. DeGrado (1995)
Science 270, 935-941
 |  Abstract »  |  PDF »

Guidelines for Protein Design: The Energetics of beta Sheet Side Chain Interactions.

C. K. Smith and L. Regan (1995)
Science 270, 980-982
 |  Abstract »  |  PDF »

The Effects of Interhelical Electrostatic Repulsions between Glutamic Acid Residues in Controlling the Dimerization and Stability of Two-stranded alpha-Helical Coiled-coils.

W. D. Kohn, O. D. Monera, C. M. Kay, and R. S. Hodges (1995)
J. Biol. Chem. 270, 25495-25506
 |  Abstract »  |  Full Text »  |  PDF »

Solution Assembly of a Soluble, Heteromeric, High Affinity Interleukin-2 Receptor Complex.

Z. Wu, K. W. Johnson, B. Goldstein, Y. Choi, S. F. Eaton, T. M. Laue, and T. L. Ciardelli (1995)
J. Biol. Chem. 270, 16039-16044
 |  Abstract »  |  Full Text »  |  PDF »

Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper.

K. Lumb and P. Kim (1995)
Science 268, 436-439
 |  Abstract »  |  PDF »

Mutagenesis of the Regulatory Subunit (RIIbeta) of cAMP-dependent Protein Kinase IIbeta Reveals Hydrophobic Amino Acids That Are Essential for RIIbeta Dimerization and/or Anchoring RIIbeta to the Cytoskeleton.

Y. Li and C. S. Rubin (1995)
J. Biol. Chem. 270, 1935-1944
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Amphipathicity in the Folding, Self-association and Biological Activity of Multiple Subunit Small Proteins.

E. Pérez-Payá, R. A. Houghten, and S. E. Blondelle (1995)
J. Biol. Chem. 270, 1048-1056
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Protein design by binary patterning of polar and nonpolar amino acids.

S Kamtekar, J. Schiffer, H Xiong, J. Babik, and M. Hecht (1993)
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A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants.

P. Harbury, T Zhang, P. Kim, and T Alber (1993)
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Structure at 2.5 A of a designed peptide that maintains solubility of membrane proteins.

C. Schafmeister, L. Miercke, and R. Stroud (1993)
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Structural basis of amino acid alpha helix propensity.

M Blaber, X. Zhang, and B. Matthews (1993)
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JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers..

T Deng and M Karin (1993)
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Crystal structure of a synthetic triple-stranded alpha-helical bundle.

B Lovejoy, S Choe, D Cascio, D. McRorie, W. DeGrado, and D Eisenberg (1993)
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Role of transmembrane domain interactions in the assembly of class II MHC molecules.

P Cosson and J. Bonifacino (1992)
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Internal stark effect measurement of the electric field at the amino terminus of an alpha helix.

D. Lockhart and P. Kim (1992)
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X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil.

E. O'Shea, J. Klemm, P. Kim, and T Alber (1991)
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An Intrahelical Salt Bridge within the Trigger Site Stabilizes the GCN4 Leucine Zipper.

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