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Science 12 October 1990:
Vol. 250. no. 4978, pp. 282 - 285
DOI: 10.1126/science.2218532
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Articles

Science, Vol 250, Issue 4978, 282-285
Copyright © 1990 by American Association for the Advancement of Science

articles

In vitro reconstruction of the respiratory central pattern generator of the mollusk Lymnaea

NI Syed, AG Bulloch, and K Lukowiak

Neuroscience Research Group, University of Calgary, Canada.

Most rhythmic behaviors such as respiration, locomotion, and feeding are under the control of networks of neurons in the central nervous system known as central pattern generators (CPGs). The respiratory rhythm of the pond snail Lymnaea stagnalis is a relatively simple, CPG-based behavior for which the underlying neural elements have been identified. A three-neuron network capable of generating the respiratory rhythm of this air-breathing mollusk has been reconstructed in culture. The intrinsic and network properties of this neural ensemble have been studied, and the mechanism of postinhibitory rebound excitation was found to be important for the rhythm generation. This in vitro model system enables a better understanding of the neural basis of rhythm generation.


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Intermediate and long-term memories of associative learning are differentially affected by transcription versus translation blockers inLymnaea.
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Hypoxia-Induced Respiratory Patterned Activity in Lymnaea Originates at the Periphery.
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Context Learning and the Effect of Context on Memory Retrieval in Lymnaea.
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Trophic Factor-Induced Plasticity of Synaptic Connections Between Identified Lymnaea Neurons.
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Learn. Mem. 6, 307-316
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Neuromodulation Intrinsic to the Central Pattern Generator for Escape Swimming in Tritonia.
P. S. KATZ (1998)
Ann. N.Y. Acad. Sci. 860, 181-188
   Abstract »    Full Text »    PDF »
Trophic and Contact Conditions Modulate Synapse Formation Between Identified Neurons.
N. S. Magoski and A. G. M. Bulloch (1998)
J Neurophysiol 79, 3279-3283
   Abstract »    Full Text »    PDF »
Contingent-Dependent Enhancement of Rhythmic Motor Patterns: An In Vitro Analog of Operant Conditioning.
R. Nargeot, D. A. Baxter, and J. H. Byrne (1997)
J. Neurosci. 17, 8093-8105
   Abstract »    Full Text »    PDF »
In Vitro Synaptogenesis between the Somata of Identified Lymnaea Neurons Requires Protein Synthesis But Not Extrinsic Growth Factors or Substrate Adhesion Molecules.
Z.-P. Feng, J. Klumperman, K. Lukowiak, and N. I. Syed (1997)
J. Neurosci. 17, 7839-7849
   Abstract »    Full Text »    PDF »
The high culture of neuroscience.
M Barinaga (1990)
Science 250, 206-207
   PDF »
Synapse Formation between Central Neurons Requires Postsynaptic Expression of the MEN1 Tumor Suppressor Gene.
R. E. van Kesteren, N. I. Syed, D. W. Munno, J. Bouwman, Z.-P. Feng, W. P. M. Geraerts, and A. B. Smit (2001)
J. Neurosci. 21, RC161
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)