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Science 10 August 1990: Vol. 249. no. 4969, pp. 635 - 640 DOI: 10.1126/science.2116664
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Articles
Science, Vol 249, Issue 4969, 635-640
Copyright © 1990 by American Association for the Advancement of Science
The cellular functions of small GTP-binding proteins
A Hall
Chester Beatty Laboratories, Institute of Cancer Research, London, Great Britain.
A substantial number of novel guanine nucleotide binding regulatory proteins have been identified over the last few years but the function of many of them is largely unknown. This article will discuss a particular family of these proteins, structurally related to the Ras oncoprotein. Approximately 30 Ras-related small guanosine triphosphate (GTP)-binding proteins are known, and from yeast to man they appear to be involved in controlling a diverse set of essential cellular functions including growth, differentiation, cytoskeletal organization, and intracellular vesicle transport and secretion.
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| Abstract »
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| Abstract »
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| Abstract »
| Full Text »
| PDF »
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| Full Text »
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| Abstract »
| Full Text »
| PDF »
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| Full Text »
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| Abstract »
| Full Text »
| PDF »
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125, 453-461
| Abstract »
| PDF »
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- W.-J. Wu, D. A. Leonard, R. A-Cerione, and D. Manor (1997)
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272, 26153-26158
| Abstract »
| Full Text »
| PDF »
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- J. Jiang and R. J. Roman (1997)
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30, 968-974
| Abstract »
| Full Text »
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- Z. Jin and S. M. Strittmatter (1997)
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17, 6256-6263
| Abstract »
| Full Text »
| PDF »
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- N. J. D'Silva, D. H. DiJulio, C. M. Belton, K. L. Jacobson, and E. L. Watson (1997)
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45, 965-974
| Abstract »
| Full Text »
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N. Engl. J. Med.
336, 1713-1720
| Abstract »
| Full Text »
| PDF »
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- A. Casamassima and E. Rozengurt (1997)
J. Biol. Chem.
272, 9363-9370
| Abstract »
| Full Text »
| PDF »
- rho, a Small GTP-Binding Protein, Is Essential for Shigella Invasion of Epithelial Cells.
- M. Watarai, Y. Kamata, S. Kozaki, and C. Sasakawa (1997)
J. Exp. Med.
185, 281-292
| Abstract »
| Full Text »
| PDF »
- Rin, a Neuron-Specific and Calmodulin-Binding Small G-Protein, and Rit Define a Novel Subfamily of Ras Proteins.
- C.-H. J. Lee, N. G. Della, C. E. Chew, and D. J. Zack (1996)
J. Neurosci.
16, 6784-6794
| Abstract »
| Full Text »
| PDF »
- Fas-induced Apoptosis Is Mediated by Activation of a Ras and Rac Protein-regulated Signaling Pathway.
- E. Gulbins, K.M. Coggeshall, B. Brenner, K. Schlottmann, O. Linderkamp, and F. Lang (1996)
J. Biol. Chem.
271, 26389-26394
| Abstract »
| Full Text »
| PDF »
- The Ca2+-dependent Lipid Binding Domain of P120GAP Mediates Protein-Protein Interactions with Ca2+-dependent Membrane-binding Proteins. EVIDENCE FOR A DIRECT INTERACTION BETWEEN ANNEXIN VI AND P120GAP.
- A. J. Davis, J. T. Butt, J. H. Walker, S. E. Moss, and D. J. Gawler (1996)
J. Biol. Chem.
271, 24333-24336
| Abstract »
| Full Text »
| PDF »
- The Ras-related GTPase Rac1 Binds Tubulin.
- A. Best, S. Ahmed, R. Kozma, and L. Lim (1996)
J. Biol. Chem.
271, 3756-3762
| Abstract »
| Full Text »
| PDF »
- Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs.
- H Dutartre, J Davoust, J. Gorvel, and P Chavrier (1996)
J. Cell Sci.
109, 367-377
| Abstract »
| PDF »
- The mammalian ARF-like protein 1 (Arl1) is associated with the Golgi complex.
- S. Lowe, S. Wong, and W Hong (1996)
J. Cell Sci.
109, 209-220
| Abstract »
| PDF »
- Cloning of a Novel Family of Mammalian GTP-binding Proteins (RagA, RagB^s, RagB^l) with Remote Similarity to the Ras-related GTPases.
- A. Schürmann, A. Brauers, S. Maßmann, W. Becker, and H.-G. Joost (1995)
J. Biol. Chem.
270, 28982-28988
| Abstract »
| Full Text »
| PDF »
- Identification and Molecular Cloning of a p21[IMAGE]-activated Serine/Threonine Kinase That Is Rapidly Activated by Thrombin in Platelets.
- M. Teo, E. Manser, and L. Lim (1995)
J. Biol. Chem.
270, 26690-26697
| Abstract »
| Full Text »
| PDF »
- A 68-kDa Kinase and NADPH Oxidase Component p67 Are Targets for Cdc42Hs and Rac1 in Neutrophils.
- E. Prigmore, S. Ahmed, A. Best, R. Kozma, E. Manser, A. W. Segal, and L. Lim (1995)
J. Biol. Chem.
270, 10717-10722
| Abstract »
| Full Text »
| PDF »
- Divergent Insulin and Platelet-derived Growth Factor Regulation of Focal Adhesion Kinase (pp125[IMAGE]) Tyrosine Phosphorylation, and Rearrangement of Actin Stress Fibers.
- J. B. Knight, K. Yamauchi, and J. E. Pessin (1995)
J. Biol. Chem.
270, 10199-10203
| Abstract »
| Full Text »
| PDF »
- Isoprenylation of Plant Proteins in Vivo.
- C. A. Shipton, I. Parmryd, E. Swiezewska, B. Andersson, and G. Dallner (1995)
J. Biol. Chem.
270, 566-572
| Abstract »
| Full Text »
| PDF »
- Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein rho.
- Y Horiguchi, T Senda, N Sugimoto, J Katahira, and M Matsuda (1995)
J. Cell Sci.
108, 3243-3251
| Abstract »
| PDF »
- The small GTP-binding protein, rho p21, is involved in bone resorption by regulating cytoskeletal organization in osteoclasts.
- D Zhang, N Udagawa, I Nakamura, H Murakami, S Saito, K Yamasaki, Y Shibasaki, N Morii, S Narumiya, N Takahashi, et al. (1995)
J. Cell Sci.
108, 2285-2292
| Abstract »
| PDF »
- Polarized exocytosis in MDCK cells is regulated by phosphorylation.
- C. Brewer and M. Roth (1995)
J. Cell Sci.
108, 789-796
| Abstract »
| PDF »
- Loss of The Normal NF1 Allele from the Bone Marrow of Children with Type 1 Neurofibromatosis and Malignant Myeloid Disorders.
- K. M. Shannon, P. O'Connell, G. A. Martin, D. Paderanga, K. Olson, P. Dinndorf, and F. McCormick (1994)
N. Engl. J. Med.
330, 597-601
| Abstract »
| Full Text »
- Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans.
- C Reynet and C. Kahn (1993)
Science
262, 1441-1444
| Abstract »
| PDF »
- Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation.
- E Gulbins, K. Coggeshall, G Baier, S Katzav, P Burn, and A Altman (1993)
Science
260, 822-825
| Abstract »
| PDF »
- Protein prenylation: a mediator of protein-protein interactions.
- C. Marshall (1993)
Science
259, 1865-1866
| PDF »
- A functional role for GTP-binding proteins in synaptic vesicle cycling.
- S. Hess, P. Doroshenko, and G. Augustine (1993)
Science
259, 1169-1172
| Abstract »
| PDF »
- Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils.
- M. Philips, M. Pillinger, R Staud, C Volker, M. Rosenfeld, G Weissmann, and J. Stock (1993)
Science
259, 977-980
| Abstract »
- Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP-mediated signaling.
- M Duchesne, F Schweighoffer, F Parker, F Clerc, Y Frobert, M. Thang, and B Tocque (1993)
Science
259, 525-528
| Abstract »
| PDF »
- Rab6 is associated with a compartment that transports rhodopsin from the trans-Golgi to the site of rod outer segment disk formation in frog retinal photoreceptors.
- D Deretic and D. Papermaster (1993)
J. Cell Sci.
106, 803-813
| Abstract »
| PDF »
- v-ras and protein kinase C dedifferentiate thyroid cells by down-regulating nuclear cAMP-dependent protein kinase A..
- A Gallo, E Benusiglio, I M Bonapace, A Feliciello, S Cassano, C Garbi, A M Musti, M E Gottesman, and E V Avvedimento (1992)
Genes & Dev.
6, 1621-1630
| Abstract »
| PDF »
- PCR regimen for enhanced specificity and yield of targeted genomic DNA sequences: ras and p53..
- D J Phillips, J M Benson, J M Pruckler, and W C Hooper (1992)
Genome Res.
2, 45-50
| Abstract »
| PDF »
- Biological Mechanisms of Fluorosis and Level and Timing of Systemic Exposure to Fluoride with Respect to Fluorosis.
- P.K. Denbesten and H. Thariani (1992)
Journal of Dental Research
71, 1238-1243
| Abstract »
| PDF »
- Signal Transduction Mechanisms Involved in Salivary Gland Regulated Exocytosis.
- D. O. Quissell, E. Watson, and F. J. Dowd (1992)
Critical Reviews in Oral Biology & Medicine
3, 83-107
| Full Text »
| PDF »
- Distinct Patterns of Actin Organization Regulated by the Small GTP-binding Proteins Rac and Rho.
- A.J. Ridley and A. Hall (1992)
Cold Spring Harb Symp Quant Biol
57, 661-671
| Abstract »
| PDF »
- Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A.
- G. Bokoch, L. Quilliam, B. Bohl, A. Jesaitis, and M. Quinn (1991)
Science
254, 1794-1796
| Abstract »
| PDF »
- Heterogeneous amino acids in Ras and Rap1A specifying sensitivity to GAP proteins.
- K Zhang, A. Papageorge, P Martin, W. Vass, Z Olah, P. Polakis, F McCormick, and D. Lowy (1991)
Science
254, 1630-1634
| Abstract »
| PDF »
- Molecular cloning of a member of a new class of low-molecular-weight GTP-binding proteins..
- B H Morimoto, C C Chuang, and D E Koshland (1991)
Genes & Dev.
5, 2386-2391
| Abstract »
| PDF »
- Differentiation of 3T3-L1 fibroblasts to adipocytes induced by transfection of ras oncogenes.
- M Benito, A Porras, A. Nebreda, and E Santos (1991)
Science
253, 565-568
| Abstract »
| PDF »
- Diversity of G proteins in signal transduction.
- M. Simon, M. Strathmann, and N Gautam (1991)
Science
252, 802-808
| Abstract »
| PDF »
- Antiinflammatory and Antiarteriosclerotic Actions of HMG-CoA Reductase Inhibitors in a Rat Model of Chronic Inhibition of Nitric Oxide Synthesis.
- W. Ni, K. Egashira, C. Kataoka, S. Kitamoto, M. Koyanagi, S. Inoue, and A. Takeshita (2001)
Circ. Res.
89, 415-421
| Abstract »
| Full Text »
| PDF »
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