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Science 22 June 1990: Vol. 248. no. 4962, pp. 1537 - 1539 DOI: 10.1126/science.1694307
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Articles
Science, Vol 248, Issue 4962, 1537-1539
Copyright © 1990 by American Association for the Advancement of Science
Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins
M Matsuda,
BJ Mayer,
Y Fukui,
and
H Hanafusa
Rockefeller University, New York, NY 10021.
Although the oncogene product of CT10 virus, P47gag-crk, does not itself phosphorylate proteins at tyrosine residues, it elevates phosphotyrosine in transformed cells. The P47gag-crk oncoprotein contains SH2 and SH3 domains, which are conserved in several proteins involved in signal transduction, including nonreceptor tyrosine kinases. P47gag-crk bound in vitro to phosphotyrosine-containing proteins from crk-transformed cells and from cells transformed by oncogenic tyrosine kinases. The association between P47gag-crk and p60v-src, a phosphotyrosine-containing protein, was abolished by dephosphorylation of p60v-src. This suggests that the SH2 and SH3 regions function to regulate protein interactions in a phosphotyrosine-dependent manner.
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| Abstract »
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| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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- M. Nievers, R. Birge, H Greulich, A. Verkleij, H Hanafusa, and P. van Bergen en Henegouwen (1997)
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110, 389-399
| Abstract »
| PDF »
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- F. Liu, D. E. Hill, and J. Chernoff (1996)
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271, 31290-31295
| Abstract »
| Full Text »
| PDF »
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- S. Li, J. Couet, and M. P. Lisanti (1996)
J. Biol. Chem.
271, 29182-29190
| Abstract »
| Full Text »
| PDF »
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- P. B. Allen and L. M. Wiedemann (1996)
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271, 19585-19591
| Abstract »
| Full Text »
| PDF »
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- M. Matsuda, S. Ota, R. Tanimura, H. Nakamura, K. Matuoka, T. Takenawa, K. Nagashima, and T. Kurata (1996)
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271, 14468-14472
| Abstract »
| Full Text »
| PDF »
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- M. T. Harte, J. D. Hildebrand, M. R. Burnham, A. H. Bouton, and J. T. Parsons (1996)
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271, 13649-13655
| Abstract »
| Full Text »
| PDF »
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- T. Nakamoto, R. Sakai, K. Ozawa, Y. Yazaki, and H. Hirai (1996)
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271, 8959-8965
| Abstract »
| Full Text »
| PDF »
- Nerve Growth Factor Stimulates the Tyrosine Phosphorylation of Endogenous Crk-II and Augments Its Association with p130[IMAGE] in PC-12 Cells.
- V. Ribon and A. R. Saltiel (1996)
J. Biol. Chem.
271, 7375-7380
| Abstract »
| Full Text »
| PDF »
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- L. Petruzzelli, M. Takami, and R. Herrera (1996)
J. Biol. Chem.
271, 7796-7801
| Abstract »
| Full Text »
| PDF »
- Coupling of the Proto-oncogene Product c-Cbl to the Epidermal Growth Factor Receptor.
- H. Meisner and M. P. Czech (1995)
J. Biol. Chem.
270, 25332-25335
| Abstract »
| Full Text »
| PDF »
- Tyrosine Phosphorylation of p130[IMAGE] and Cortactin Accompanies Integrin-mediated Cell Adhesion to Extracellular Matrix.
- K. Vuori and E. Ruoslahti (1995)
J. Biol. Chem.
270, 22259-22262
| Abstract »
| Full Text »
| PDF »
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- K. K. Teng, H. Lander, J. E. Fajardo, H. Hanafusa, B. L. Hempstead, and R. B. Birge (1995)
J. Biol. Chem.
270, 20677-20685
| Abstract »
| Full Text »
| PDF »
- The SH3 Domain of Crk Binds Specifically to a Conserved Proline-rich Motif in Eps15 and Eps15R.
- C. Schumacher, B. S. Knudsen, T. Ohuchi, P. P. D. Fiore, R. H. Glassman, and H. Hanafusa (1995)
J. Biol. Chem.
270, 15341-15347
| Abstract »
| Full Text »
| PDF »
- Sequence Requirements for Binding of Src Family Tyrosine Kinases to Activated Growth Factor Receptors.
- G. Alonso, M. Koegl, N. Mazurenko, and S. A. Courtneidge (1995)
J. Biol. Chem.
270, 9840-9848
| Abstract »
| Full Text »
| PDF »
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- R Ren, Z S Ye, and D Baltimore (1994)
Genes & Dev.
8, 783-795
| Abstract »
| PDF »
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- J Merilainen, R Palovuori, R Sormunen, V. Wasenius, and V. Lehto (1993)
J. Cell Sci.
105, 647-654
| Abstract »
| PDF »
- A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region.
- A Bellacosa, Testa JR, S. Staal, and P. Tsichlis (1991)
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254, 274-277
| Abstract »
| PDF »
- Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association.
- M Hatakeyama, T Kono, N Kobayashi, A Kawahara, S. Levin, R. Perlmutter, and T Taniguchi (1991)
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252, 1523-1528
| Abstract »
| PDF »
- SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins.
- C. Koch, D Anderson, M. Moran, C Ellis, and T Pawson (1991)
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252, 668-674
| Abstract »
| PDF »
- Presence of an SH2 domain in the actin-binding protein tensin.
- S Davis, M. Lu, S. Lo, S Lin, J. Butler, B. Druker, T. Roberts, Q An, and L. Chen (1991)
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252, 712-715
| Abstract »
| PDF »
- cdc2 Protein Kinase: Interactions with Cyclins and sucl.
- P. Brambilla, B. Ducommun, and G. Draetta (1991)
Cold Spring Harb Symp Quant Biol
56, 515-521
| Abstract »
| PDF »
- Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors.
- D Anderson, C. Koch, L Grey, C Ellis, M. Moran, and T Pawson (1990)
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250, 979-982
| Abstract »
| PDF »
- Potent Blockade of Hepatocyte Growth Factor-stimulated Cell Motility, Matrix Invasion and Branching Morphogenesis by Antagonists of Grb2 Src Homology 2 Domain Interactions.
- N. Atabey, Y. Gao, Z.-J. Yao, D. Breckenridge, L. Soon, J. V. Soriano, T. R. Burke Jr., and D. P. Bottaro (2001)
J. Biol. Chem.
276, 14308-14314
| Abstract »
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| PDF »
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- D. Mielenz, S. Hapke, E. Poschl, H. von der Mark, and K. von der Mark (2001)
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276, 13417-13426
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- K. L. Pierce, A. Tohgo, S. Ahn, M. E. Field, L. M. Luttrell, and R. J. Lefkowitz (2001)
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