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Science 8 June 1990:
Vol. 248. no. 4960, pp. 1194 - 1199
DOI: 10.1126/science.248.4960.1194
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Articles

Chiral Metal Complexes as Discriminating Molecular Catalysts

Ryoji Noyori 1

1 Department of Chemistry, Nagoya University, Chikusa, Nagoya 464-01, Japan

As molecular recognition continues to gain importance in the biological and physical sciences as well as in the technologies of molecular electronics and optics, so has the need for efficient syntheses of chiral molecules. Chemists are fulfilling this need through use of chiral organometallic molecules. These chiral metal complexes precisely discriminate between enantiotopic atoms, groups, or faces in achiral molecules and catalyze production of a broad array of natural or unnatural substances of excellent enantiomeric purity. Because of their ability to efficiently multiply chirality, even on an industrial level, these catalysts promise to exert a general impact on molecular science and engineering.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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