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Science 1 June 1990: Vol. 248. no. 4959, pp. 1112 - 1115 DOI: 10.1126/science.2188365
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Articles
Science, Vol 248, Issue 4959, 1112-1115
Copyright © 1990 by American Association for the Advancement of Science
HSP104 required for induced thermotolerance
Y Sanchez
and
SL Lindquist
Howard Hughes Medical Institute, Department of Molecular Genetics and Cell Biology, University of Chicago, Illinois 60637.
A heat shock protein gene, HSP104, was isolated from Saccharomyces cerevisiae and a deletion mutation was introduced into yeast cells. Mutant cells grew at the same rate as wild-type cells and died at the same rate when exposed directly to high temperatures. However, when given a mild pre-heat treatment, the mutant cells did not acquire tolerance to heat, as did wild-type cells. Transformation with the wild-type gene rescued the defect of mutant cells. The results demonstrate that a particular heat shock protein plays a critical role in cell survival at extreme temperatures.
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| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
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| Abstract »
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| PDF »
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64, 1400-1404
| Abstract »
| Full Text »
| PDF »
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- N Saris and M Makarow (1998)
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111, 1575-1582
| Abstract »
| PDF »
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- D. H. Lee and A. L. Goldberg (1998)
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18, 30-38
| Abstract »
| Full Text »
| PDF »
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- E. C. Schirmer and S. Lindquist (1997)
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94, 13932-13937
| Abstract »
| Full Text »
| PDF »
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94, 10967-10972
| Abstract »
| Full Text »
| PDF »
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272, 24646-24656
| Abstract »
| Full Text »
| PDF »
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- N. Saris, H. Holkeri, R. A. Craven, C. J. Stirling, and M. Makarow (1997)
J. Cell Biol.
137, 813-824
| Abstract »
| Full Text »
| PDF »
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- M. Amrani, J. Corbett, S. Y. Boateng, M. J. Dunn, and M. H. Yacoub (1996)
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61, 1407-1411
| Abstract »
| Full Text »
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- M. Yonehara, Y. Minami, Y. Kawata, J. Nagai, and I. Yahara (1996)
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271, 2641-2645
| Abstract »
| Full Text »
| PDF »
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- K. Yasuda, A. Nakai, T. Hatayama, and K. Nagata (1995)
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270, 29718-29723
| Abstract »
| Full Text »
| PDF »
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- P. Fung, J Gaertig, M. Gorovsky, and R. Hallberg (1995)
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268, 1036-1039
| Abstract »
| PDF »
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- Y. Chernoff, S. Lindquist, B Ono, S. Inge-Vechtomov, and S. Liebman (1995)
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268, 880-884
| Abstract »
| PDF »
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- S. Lindquist, M.M. Patino, Y.O. Chernoff, A.S. Kowal, M.A. Singer, S.W. Liebman, K.-H. Lee, and T. Blake (1995)
Cold Spring Harb Symp Quant Biol
60, 451-460
| Abstract »
| PDF »
- Thermotolerance in mammalian cells. Protein denaturation and aggregation, and stress proteins.
- H. Kampinga (1993)
J. Cell Sci.
104, 11-17
| Abstract »
| PDF »
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| Abstract »
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- K. Kustedjo, M. H. Bracey, and B. F. Cravatt (2000)
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| Abstract »
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