Science 20 April 1990: Vol. 248. no. 4953, pp. 378 - 381 DOI: 10.1126/science.2326648

Prev | Table of Contents | Next

Articles

ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling.

A. D. Wood, E. Chen, I. J. Donaldson, S. Hattangadi, K. A. Burke, M. A. Dawson, D. Miranda-Saavedra, H. F. Lodish, A. R. Green, and B. Gottgens (2009)
Blood 114, 1820-1830
 |  Abstract »  |  Full Text »  |  PDF »

Erythroblastic islands: niches for erythropoiesis.

J. A. Chasis and N. Mohandas (2008)
Blood 112, 470-478
 |  Abstract »  |  Full Text »  |  PDF »

EPO receptor circuits for primary erythroblast survival.

P. Sathyanarayana, A. Dev, J. Fang, E. Houde, O. Bogacheva, O. Bogachev, M. Menon, S. Browne, A. Pradeep, C. Emerson, et al. (2008)
Blood 111, 5390-5399
 |  Abstract »  |  Full Text »  |  PDF »

Osteopontin Regulates Actin Cytoskeleton and Contributes to Cell Proliferation in Primary Erythroblasts.

J.-A. Kang, Y. Zhou, T. L. Weis, H. Liu, J. Ulaszek, N. Satgurunathan, L. Zhou, K. van Besien, J. Crispino, A. Verma, et al. (2008)
J. Biol. Chem. 283, 6997-7006
 |  Abstract »  |  Full Text »  |  PDF »

Adherence to macrophages in erythroblastic islands enhances erythroblast proliferation and increases erythrocyte production by a different mechanism than erythropoietin.

M. M. Rhodes, P. Kopsombut, M. C. Bondurant, J. O. Price, and M. J. Koury (2008)
Blood 111, 1700-1708
 |  Abstract »  |  Full Text »  |  PDF »

EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts.

J. Fang, M. Menon, W. Kapelle, O. Bogacheva, O. Bogachev, E. Houde, S. Browne, P. Sathyanarayana, and D. M. Wojchowski (2007)
Blood 110, 2361-2370
 |  Abstract »  |  Full Text »  |  PDF »

Functional conservation of erythropoietin signaling in zebrafish.

N. Paffett-Lugassy, N. Hsia, P. G. Fraenkel, B. Paw, I. Leshinsky, B. Barut, N. Bahary, J. Caro, R. Handin, and L. I. Zon (2007)
Blood 110, 2718-2726
 |  Abstract »  |  Full Text »  |  PDF »

HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques.

M. M. Hsieh, N. S. Linde, A. Wynter, M. Metzger, C. Wong, I. Langsetmo, A. Lin, R. Smith, G. P. Rodgers, R. E. Donahue, et al. (2007)
Blood 110, 2140-2147
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin modulation of podocalyxin and a proposed erythroblast niche.

P. Sathyanarayana, M. P. Menon, O. Bogacheva, O. Bogachev, K. Niss, W. S. Kapelle, E. Houde, J. Fang, and D. M. Wojchowski (2007)
Blood 110, 509-518
 |  Abstract »  |  Full Text »  |  PDF »

Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis.

A. Diwan, A. G. Koesters, A. M. Odley, S. Pushkaran, C. P. Baines, B. T. Spike, D. Daria, A. G. Jegga, H. Geiger, B. J. Aronow, et al. (2007)
PNAS 104, 6794-6799
 |  Abstract »  |  Full Text »  |  PDF »

Protective Role of Endogenous Erythropoietin System in Nonhematopoietic Cells Against Pressure Overload-Induced Left Ventricular Dysfunction in Mice.

Y. Asaumi, Y. Kagaya, M. Takeda, N. Yamaguchi, H. Tada, K. Ito, J. Ohta, T. Shiroto, K. Shirato, N. Minegishi, et al. (2007)
Circulation 115, 2022-2032
 |  Abstract »  |  Full Text »  |  PDF »

GATA-4 Incompletely Substitutes for GATA-1 in Promoting Both Primitive and Definitive Erythropoiesis in Vivo.

S. Hosoya-Ohmura, N. Mochizuki, M. Suzuki, O. Ohneda, K. Ohneda, and M. Yamamoto (2006)
J. Biol. Chem. 281, 32820-32830
 |  Abstract »  |  Full Text »  |  PDF »

Endogenous erythropoietin system in non-hematopoietic lineage cells plays a protective role in myocardial ischemia/reperfusion.

H. Tada, Y. Kagaya, M. Takeda, J. Ohta, Y. Asaumi, K. Satoh, K. Ito, A. Karibe, K. Shirato, N. Minegishi, et al. (2006)
Cardiovasc Res 71, 466-477
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo.

Y. Liu, R. Pop, C. Sadegh, C. Brugnara, V. H. Haase, and M. Socolovsky (2006)
Blood 108, 123-133
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin fails to interfere with the antiproliferative and cytotoxic effects of antitumor drugs..

D. A. Gewirtz, X. Di, T. D. Walker, and S. T. Sawyer (2006)
Clin. Cancer Res. 12, 2232-2238
 |  Abstract »  |  Full Text »  |  PDF »

Core erythropoietin receptor signals for late erythroblast development.

M. P. Menon, J. Fang, and D. M. Wojchowski (2006)
Blood 107, 2662-2672
 |  Abstract »  |  Full Text »  |  PDF »

Closing the TRAIL to the DISC.

R. T. Means Jr (2006)
Blood 107, 418-419
 |  Full Text »  |  PDF »

Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins.

S. W. Krauss, A. J. Lo, S. A. Short, M. J. Koury, N. Mohandas, and J. A. Chasis (2005)
Blood 106, 2200-2205
 |  Abstract »  |  Full Text »  |  PDF »

Antiapoptotic Role of Growth Factors in the Myelodysplastic Syndromes: Concordance Between In vitro and In vivo Observations.

R. Tehranchi, B. Fadeel, J. Schmidt-Mende, A.-M. Forsblom, E. Emanuelsson, M. Jadersten, B. Christensson, R. Hast, R. B. Howe, J. Samuelsson, et al. (2005)
Clin. Cancer Res. 11, 6291-6299
 |  Abstract »  |  Full Text »  |  PDF »

Bcl-xL prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin.

M. M. Rhodes, P. Kopsombut, M. C. Bondurant, J. O. Price, and M. J. Koury (2005)
Blood 106, 1857-1863
 |  Abstract »  |  Full Text »  |  PDF »

Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways.

W. Tong, J. Zhang, and H. F. Lodish (2005)
Blood 105, 4604-4612
 |  Abstract »  |  Full Text »  |  PDF »

Two-phase culture in Diamond Blackfan anemia: localization of erythroid defect.

Y. Ohene-Abuakwa, K. A. Orfali, C. Marius, and S. E. Ball (2005)
Blood 105, 838-846
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin and the hypoxic brain.

H. H. Marti (2004)
J. Exp. Biol. 207, 3233-3242
 |  Abstract »  |  Full Text »  |  PDF »

Jun N-terminal kinase promotes proliferation of immature erythroid cells and erythropoietin-dependent cell lines.

S. M. Jacobs-Helber and S. T. Sawyer (2004)
Blood 104, 696-703
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Erythropoietin Axotomy-Induced Apoptosis in Rat Retinal Ganglion Cells.

J. H. Weishaupt, G. Rohde, E. Polking, A.-L. Siren, H. Ehrenreich, and M. Bahr (2004)
Invest. Ophthalmol. Vis. Sci. 45, 1514-1522
 |  Abstract »  |  Full Text »  |  PDF »

Epoetin Alfa: Clinical Evolution of a Pleiotropic Cytokine.

D. H. Henry, P. Bowers, M. T. Romano, and R. Provenzano (2004)
Arch Intern Med 164, 262-276
 |  Abstract »  |  Full Text »  |  PDF »

The Evolving Role of Epoetin Alfa in Cancer Therapy.

D. H. Henry (2004)
Oncologist 9, 97-107
 |  Abstract »  |  Full Text »  |  PDF »

Up-regulation of SLAP in FLI-1-transformed erythroblasts interferes with EpoR signaling.

I. Lebigot, P. Gardellin, L. Lefebvre, H. Beug, J. Ghysdael, and C. T. Quang (2003)
Blood 102, 4555-4562
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant Human Erythropoietin Therapy Is Very Effective after an Autologous Peripheral Blood Stem Cell Transplant When Started Soon after Engraftment.

F. Baron, P. Frere, G. Fillet, and Y. Beguin (2003)
Clin. Cancer Res. 9, 5566-5572
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Erythrocyte Cation Channels by Erythropoietin.

S. Myssina, S. M. Huber, C. Birka, P. A. Lang, K. S. Lang, B. Friedrich, T. Risler, T. Wieder, and F. Lang (2003)
J. Am. Soc. Nephrol. 14, 2750-2757
 |  Abstract »  |  Full Text »  |  PDF »

Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor cells.

K. Li, M. P. Menon, V. G. Karur, S. Hegde, and D. M. Wojchowski (2003)
Blood 102, 3147-3153
 |  Abstract »  |  Full Text »  |  PDF »

Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury.

Z. Cai, D. J. Manalo, G. Wei, E. R. Rodriguez, K. Fox-Talbot, H. Lu, J. L. Zweier, and G. L. Semenza (2003)
Circulation 108, 79-85
 |  Abstract »  |  Full Text »  |  PDF »

Increased Expression of Erythropoiesis Inhibiting Cytokines (IFN-{gamma}, TNF-{alpha}, IL-10, and IL-13) by T Cells in Patients Exhibiting a Poor Response to Erythropoietin Therapy.

A. C. Cooper, A. Mikhail, M. W. Lethbridge, D. M. Kemeny, and I. C. Macdougall (2003)
J. Am. Soc. Nephrol. 14, 1776-1784
 |  Abstract »  |  Full Text »  |  PDF »

Loss of HSulf-1 Up-regulates Heparin-binding Growth Factor Signaling in Cancer.

J. Lai, J. Chien, J. Staub, R. Avula, E. L. Greene, T. A. Matthews, D. I. Smith, S. H. Kaufmann, L. R. Roberts**, and V. Shridhar** (2003)
J. Biol. Chem. 278, 23107-23117
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin regulates tumour growth of human malignancies.

Y. Yasuda, Y. Fujita, T. Matsuo, S. Koinuma, S. Hara, A. Tazaki, M. Onozaki, M. Hashimoto, T. Musha, K. Ogawa, et al. (2003)
Carcinogenesis 24, 1021-1029
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin receptor signalling is required for normal brain development.

X. Yu, J. J. Shacka, J. B. Eells, C. Suarez-Quian, R. M. Przygodzki, B. Beleslin-Cokic, C.-S. Lin, V. M. Nikodem, B. Hempstead, K. C. Flanders, et al. (2003)
Development 129, 505-516
 |  Abstract »  |  Full Text »  |  PDF »

Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions.

G. Lee, F. A. Spring, S. F. Parsons, T. J. Mankelow, L. L. Peters, M. J. Koury, N. Mohandas, D. J. Anstee, and J. A. Chasis (2003)
Blood 101, 1790-1797
 |  Abstract »  |  Full Text »  |  PDF »

Polycythemia vera: myths, mechanisms, and management.

J. L. Spivak (2002)
Blood 100, 4272-4290
 |  Full Text »  |  PDF »

The death-promoting activity of p53 can be inhibited by distinct signaling pathways.

Y. Lin, L. Brown, D. W. Hedley, D. L. Barber, and S. Benchimol (2002)
Blood 100, 3990-4000
 |  Abstract »  |  Full Text »  |  PDF »

Purification and characterization of the yeast-expressed erythropoietin mutant Epo (R103A), a specific inhibitor of human primary hematopoietic cell erythropoiesis.

S. Burns, M. O. Arcasoy, L. Li, E. Kurian, K. Selander, P. D. Emanuel, and K. W. Harris (2002)
Blood 99, 4400-4405
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Erythropoietin-induced STAT Serine Phosphorylation by Distinct Mitogen-activated Protein Kinases.

R. Haq, A. Halupa, B. K. Beattie, J. M. Mason, B. W. Zanke, and D. L. Barber (2002)
J. Biol. Chem. 277, 17359-17366
 |  Abstract »  |  Full Text »  |  PDF »

Ineffective erythropoiesis in Stat5a-/-5b-/- mice due to decreased survival of early erythroblasts.

M. Socolovsky, H.-s. Nam, M. D. Fleming, V. H. Haase, C. Brugnara, and H. F. Lodish (2001)
Blood 98, 3261-3273
 |  Abstract »  |  Full Text »  |  PDF »

Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.

T. C. P. Somervaille, D. C. Linch, and A. Khwaja (2001)
Blood 98, 1374-1381
 |  Abstract »  |  Full Text »  |  PDF »

Receptor binding cancer antigen expressed on SiSo cells, a novel regulator of apoptosis of erythroid progenitor cells.

T. Matsushima, M. Nakashima, K. Oshima, Y. Abe, J. Nishimura, H. Nawata, T. Watanabe, and K. Muta (2001)
Blood 98, 313-321
 |  Abstract »  |  Full Text »  |  PDF »

Out of Thin Air: The Evolving Enigma of Erythropoietin and Neocytolysis.

B. A. Harris Jr. and P. E. Epstein (2001)
Ann Intern Med 134, 710-712
 |  Full Text »  |  PDF »

Fas-L up-regulation by highly malignant myeloma plasma cells: role in the pathogenesis of anemia and disease progression.

F. Silvestris, M. Tucci, P. Cafforio, and F. Dammacco (2001)
Blood 97, 1155-1164
 |  Abstract »  |  Full Text »  |  PDF »

Caspase Activation Is Required for Terminal Erythroid Differentiation.

Y. Zermati, C. Garrido, S. Amsellem, S. Fishelson, D. Bouscary, F. Valensi, B. Varet, E. Solary, and O. Hermine (2001)
J. Exp. Med. 193, 247-254
 |  Abstract »  |  Full Text »  |  PDF »

Major Hematologic Diseases in the Developing World-- New Aspects of Diagnosis and Management of Thalassemia, Malarial Anemia, and Acute Leukemia.

P. L. Greenberg, V. Gordeuk, S. Issaragrisil, N. Siritanaratkul, S. Fucharoen, and R. C. Ribeiro (2001)
Hematology 2001, 479-498
 |  Abstract »  |  Full Text »  |  PDF »

Friend erythroleukemia revisited.

P. A. Ney and A. D. D'Andrea (2000)
Blood 96, 3675-3680
 |  Full Text »  |  PDF »

Apoptosis in megaloblastic anemia occurs during DNA synthesis by a p53-independent, nucleoside-reversible mechanism.

M. J. Koury, J. O. Price, and G. G. Hicks (2000)
Blood 96, 3249-3255
 |  Abstract »  |  Full Text »  |  PDF »

A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction.

Y. Kashii, M. Uchida, K. Kirito, M. Tanaka, K. Nishijima, M. Toshima, T. Ando, K. Koizumi, T. Endoh, K.-i. Sawada, et al. (2000)
Blood 96, 941-949
 |  Abstract »  |  Full Text »  |  PDF »

Interferon gamma delays apoptosis of mature erythroid progenitor cells in the absence of erythropoietin.

I. Choi, K. Muta, A. Wickrema, S. B. Krantz, J. Nishimura, and H. Nawata (2000)
Blood 95, 3742-3749
 |  Abstract »  |  Full Text »  |  PDF »

Blood: New designs for a new millennium.

K. Kaushansky (2000)
Blood 95, 1-6
 |  Full Text »  |  PDF »

Distinct Roles of JNKs/p38 MAP Kinase and ERKs in Apoptosis and Survival of HCD-57 Cells Induced by Withdrawal or Addition of Erythropoietin.

R. Shan, J. O. Price, W. A. Gaarde, B. P. Monia, S. B. Krantz, and Z. J. Zhao (1999)
Blood 94, 4067-4076
 |  Abstract »  |  Full Text »  |  PDF »

Increased Fetal and Extramedullary Hematopoiesis in Fas-Deficient C57BL/6-lpr/lpr Mice.

E. Schneider, G. Moreau, A. Arnould, F. Vasseur, N. Khodabaccus, M. Dy, and S. Ezine (1999)
Blood 94, 2613-2621
 |  Abstract »  |  Full Text »  |  PDF »

Engagement of Gab1 and Gab2 in Erythropoietin Signaling.

A. Wickrema, S. Uddin, A. Sharma, F. Chen, Y. Alsayed, S. Ahmad, S. T. Sawyer, G. Krystal, T. Yi, K. Nishada, et al. (1999)
J. Biol. Chem. 274, 24469-24474
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin Can Induce the Expression of Bcl-xL through Stat5 in Erythropoietin-dependent Progenitor Cell Lines.

M. Silva, A. Benito, C. Sanz, F. Prosper, D. Ekhterae, G. Nunez, and J. L. Fernandez-Luna (1999)
J. Biol. Chem. 274, 22165-22169
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Evidence for an Additional Factor Required for Erythropoietin-Induced Signal Transduction.

S. L. Gaffen, S. Y. Lai, G. D. Longmore, K. D. Liu, and M. A. Goldsmith (1999)
Blood 94, 74-86
 |  Abstract »  |  Full Text »  |  PDF »

GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression.

T. Gregory, C. Yu, A. Ma, S. H. Orkin, G. A. Blobel, and M. J. Weiss (1999)
Blood 94, 87-96
 |  Abstract »  |  Full Text »  |  PDF »

bcl-x Prevents Apoptotic Cell Death of Both Primitive and Definitive Erythrocytes at the End of Maturation.

N. Motoyama, T. Kimura, T. Takahashi, T. Watanabe, and T. Nakano (1999)
J. Exp. Med. 189, 1691-1698
 |  Abstract »  |  Full Text »  |  PDF »

Fli-1, an Ets-Related Transcription Factor, Regulates Erythropoietin-Induced Erythroid Proliferation and Differentiation: Evidence for Direct Transcriptional Repression of the Rb Gene during Differentiation.

A. Tamir, J. Howard, R. R. Higgins, Y.-J. Li, L. Berger, E. Zacksenhaus, M. Reis, and Y. Ben-David (1999)
Mol. Cell. Biol. 19, 4452-4464
 |  Abstract »  |  Full Text »  |  PDF »

Unicellular-Unilineage Erythropoietic Cultures: Molecular Analysis of Regulatory Gene Expression at Sibling Cell Level.

B. L. Ziegler, R. Muller, M. Valtieri, C. P. Lamping, C. A. Thomas, M. Gabbianelli, C. Giesert, H.-J. Buhring, L. Kanz, and C. Peschle (1999)
Blood 93, 3355-3368
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin Addition to Granulocyte Colony-Stimulating Factor Abrogates Life-Threatening Neutropenia and Increases Peripheral-Blood Progenitor-Cell Mobilization After Epirubicin, Paclitaxel, and Cisplatin Combination Chemotherapy: Results of a Randomized Comparison.

L. Pierelli, A. Perillo, S. Greggi, G. Salerno, P. B. Panici, G. Menichella, A. Fattorossi, G. Leone, S. Mancuso, and G. Scambia (1999)
J. Clin. Oncol. 17, 1288
 |  Abstract »  |  Full Text »  |  PDF »

Response and prediction of response to recombinant human erythropoietin in patients with solid tumors and platinum-associated anemia.

T. Fjornes (1999)
Journal of Oncology Pharmacy Practice 5, 22-31
 |  Abstract »  |  PDF »

Apoptotic Role of Fas/Fas Ligand System in the Regulation of Erythropoiesis.

R. De Maria, U. Testa, L. Luchetti, A. Zeuner, G. Stassi, E. Pelosi, R. Riccioni, N. Felli, P. Samoggia, and C. Peschle (1999)
Blood 93, 796-803
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Identification and Functional Characterization of a Novel Protein That Mediates the Attachment of Erythroblasts to Macrophages.

M. Hanspal, Y. Smockova, and Q. Uong (1998)
Blood 92, 2940-2950
 |  Abstract »  |  Full Text »  |  PDF »

The Prolactin Receptor Rescues EpoR-/- Erythroid Progenitors and Replaces EpoR in a Synergistic Interaction With c-kit.

M. Socolovsky, A. E.J. Fallon, and H. F. Lodish (1998)
Blood 92, 1491-1496
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin Receptor and STAT5-Specific Pathways Promote SKT6 Cell Hemoglobinization.

R. C. Gregory, N. Jiang, K. Todokoro, J. Crouse, R. E. Pacifici, and D. M. Wojchowski (1998)
Blood 92, 1104-1118
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic Activation of MAP Kinase (ERK1/2) by Erythropoietin and Stem Cell Factor Is Essential for Expanded Erythropoiesis.

X. Sui, S. B. Krantz, M. You, and Z. Zhao (1998)
Blood 92, 1142-1149
 |  Abstract »  |  Full Text »  |  PDF »

The Distal Cytoplasmic Domain of the Erythropoietin Receptor Induces Granulocytic Differentiation in 32D Cells.

K. W. Harris, X.-J. Hu, S. Schultz, M. O. Arcasoy, B. G. Forget, and N. Clare (1998)
Blood 92, 1219-1224
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Bcl-x in Erythroid Precursors from Patients with Polycythemia Vera.

M. Silva, C. Richard, A. Benito, C. Sanz, I. Olalla, and J. L. Fernandez-Luna (1998)
N. Engl. J. Med. 338, 564-571
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Protein Kinase C Isoform [IMAGE] but not delta  in Human Interleukin-3-Dependent Cells Suppresses Apoptosis and Induces bcl-2 Expression.

E. Gubina, M.S. Rinaudo, Z. Szallasi, P.M. Blumberg, and R.A. Mufson (1998)
Blood 91, 823-829
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Stem Cell Factor and Erythropoietin Proliferative Co-signaling in FDC2-ER Cells.

B. Joneja, H.-C. Chen, D. Seshasayee, A. L. Wrentmore, and D. M. Wojchowski (1997)
Blood 90, 3533-3545
 |  Abstract »  |  Full Text »  |  PDF »

Endothelin-1 as an Autocrine/Paracrine Apoptosis Survival Factor for Endothelial Cells.

M. Shichiri, H. Kato, F. Marumo, and Y. Hirata (1997)
Hypertension 30, 1198-1203
 |  Abstract »  |  Full Text »

Bcl-2 Targeted Overexpression Into the Erythroid Lineage of Transgenic Mice Delays But Does Not Prevent the Apoptosis of Erythropoietin-Deprived Erythroid Progenitors.

V. Lacronique, P. Varlet, P. Mayeux, A. Porteu, S. Gisselbrecht, A. Kahn, and C. Lacombe (1997)
Blood 90, 3050-3056
 |  Abstract »  |  Full Text »  |  PDF »

Ability of Early Acting Cytokines to Directly Promote Survival and Suppress Apoptosis of Human Primitive CD34+CD38- Bone Marrow Cells With Multilineage Potential at the Single-Cell Level: Key Role of Thrombopoietin.

O. J. Borge, V. Ramsfjell, L. Cui, and S. E.W. Jacobsen (1997)
Blood 90, 2282-2292
 |  Abstract »  |  Full Text »  |  PDF »

The Roles of Bcl-XL and Apopain in the Control of Erythropoiesis by Erythropoietin.

P. A. Gregoli and M. C. Bondurant (1997)
Blood 90, 630-640
 |  Abstract »  |  Full Text »  |  PDF »

Relationship Between the Phenotypes of Circulating Erythrocytes and Cultured Erythroblasts in Paroxysmal Nocturnal Hemoglobinuria.

T. Shichishima, Y. Saitoh, T. Terasawa, K. Ogawa, and Y. Maruyama (1997)
Blood 90, 435-443
 |  Abstract »  |  Full Text »  |  PDF »

Use of Recombinant Human Erythropoietin Outside the Setting of Uremia.

M. Cazzola, F. Mercuriali, and C. Brugnara (1997)
Blood 89, 4248-4267
 |  Full Text »  |  PDF »

Apoptosis of Late-Stage Erythroblasts in Megaloblastic Anemia: Association With DNA Damage and Macrocyte Production.

M. J. Koury, D. W. Horne, Z. A. Brown, J. A. Pietenpol, B. C. Blount, B. N. Ames, R. Hard, and S. T. Koury (1997)
Blood 89, 4617-4623
 |  Abstract »  |  Full Text »  |  PDF »

Adrenomedullin as an Autocrine/Paracrine Apoptosis Survival Factor for Rat Endothelial Cells.

H. Kato, M. Shichiri, F. Marumo, and Y. Hirata (1997)
Endocrinology 138, 2615-2620
 |  Abstract »  |  Full Text »  |  PDF »

Mitogenic Signaling and Inhibition of Apoptosis via the Erythropoietin Receptor Box-1 Domain.

B. Joneja and D. M. Wojchowski (1997)
J. Biol. Chem. 272, 11176-11184
 |  Abstract »  |  Full Text »  |  PDF »

Mutant N-RAS Induces Erythroid Lineage Dysplasia in Human CD34+ Cells.

R. L. Darley, T. G. Hoy, P. Baines, R. A. Padua, and A. K. Burnett (1997)
J. Exp. Med. 185, 1337-1348
 |  Abstract »  |  Full Text »  |  PDF »

Cell Surface Organization of the Erythropoietin Receptor Complex Differs Depending on its Mode of Activation.

K. Tarr, S. S. Watowich, and G. D. Longmore (1997)
J. Biol. Chem. 272, 9099-9107
 |  Abstract »  |  Full Text »  |  PDF »

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal..

S G Kennedy, A J Wagner, S D Conzen, J Jordan, A Bellacosa, P N Tsichlis, and N Hay (1997)
Genes & Dev. 11, 701-713
 |  Abstract »  |  PDF »

Homodimerization of Erythropoietin Receptor by a Bivalent Monoclonal Antibody Triggers Cell Proliferation and Differentiation of Erythroid Precursors.

H. Schneider, W. Chaovapong, D. J. Matthews, C. Karkaria, R. T. Cass, H. Zhan, M. Boyle, T. Lorenzini, S. G. Elliott, and L. B. Giebel (1997)
Blood 89, 473-482
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-6 Inhibits Fas-Induced Apoptosis and Stress-Activated Protein Kinase Activation in Multiple Myeloma Cells.

D. Chauhan, S. Kharbanda, A. Ogata, M. Urashima, G. Teoh, M. Robertson, D. W. Kufe, and K. C. Anderson (1997)
Blood 89, 227-234
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Activation of the cdc2 Gene Is Associated with Fas-induced Apoptosis of Human Hematopoietic Cells.

Y. Furukawa, S. Iwase, Y. Terui, J. Kikuchi, T. Sakai, M. Nakamura, S. Kitagawa, and M. Kitagawa (1996)
J. Biol. Chem. 271, 28469-28477
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-3 (IL-3) Inhibits Erythropoietin-induced Differentiation in Ba/F3 Cells via the IL-3 Receptor alpha Subunit.

J. Krosl, J. E. Damen, G. Krystal, and R.K. Humphries (1996)
J. Biol. Chem. 271, 27432-27437
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C-epsilon Is Necessary for Erythropoietin's Up-regulation of c-myc and for Factor-dependent DNA Synthesis. EVIDENCE FOR DISCRETE SIGNALS FOR GROWTH AND DIFFERENTIATION.

Y. Li, K. L. Davis, and A. J. Sytkowski (1996)
J. Biol. Chem. 271, 27025-27030
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Erythropoietin (EPO) Receptor by Bivalent Anti-EPO Receptor Antibodies.

S. Elliott, T. Lorenzini, D. Yanagihara, D. Chang, and G. Elliott (1996)
J. Biol. Chem. 271, 24691-24697
 |  Abstract »  |  Full Text »  |  PDF »

Disrupted Signaling in a Mutant J2E Cell Line That Shows Enhanced Viability, but Does Not Proliferate or Differentiate, with Erythropoietin.

P. A. Tilbrook, T. Bittorf, S. J. Busfield, D. Chappell, and S. P. Klinken (1996)
J. Biol. Chem. 271, 3453-3459
 |  Abstract »  |  Full Text »  |  PDF »

The germ line regulates somatic cyst cell proliferation and fate during Drosophila spermatogenesis.

P Gonczy and S DiNardo (1996)
Development 122, 2437-2447
 |  Abstract »  |  PDF »

Erythropoietin-dependent Inhibition of Apoptosis Is Supported by Carboxyl-truncated Receptor Forms and Blocked by Dominant-negative Forms of Jak2.

H. Zhuang, Z. Niu, T.-C. He, S. V. Patel, and D. M. Wojchowski (1995)
J. Biol. Chem. 270, 14500-14504
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin-induced Transcription at the Murine beta[IMAGE]-Globin Promoter.

D. J. Taxman and D. M. Wojchowski (1995)
J. Biol. Chem. 270, 6619-6627
 |  Abstract »  |  Full Text »  |  PDF »

Programmed cell death and the control of cell survival: lessons from the nervous system.

M. Raff, B. Barres, J. Burne, H. Coles, Y Ishizaki, and M. Jacobson (1993)
Science 262, 695-700
 |  Abstract »  |  PDF »

Erythropoietin: Biology and Clinical Applications.

I. A. Tabbara (1993)
Arch Intern Med 153, 298-304
 |  Abstract »  |  PDF »

Investigating Erythropoietin Resistance.

M. J. Koury (1993)
N. Engl. J. Med. 328, 205-206
 |  Full Text »

A Truncated Erythropoietin Receptor That Fails to Prevent Programmed Cell Death of Erythroid Cells.

Y. Nakamura, N. Komatsu, and H. Nakauchi (1992)
Science 257, 1138-1141
 |  Abstract »  |  PDF »

To Advertise   |   Find Products