Related Content
Search Google Scholar for:
|
|
Science 26 January 1990: Vol. 247. no. 4941, pp. 456 - 459 DOI: 10.1126/science.1967851
|
|
Articles
Science, Vol 247, Issue 4941, 456-459
Copyright © 1990 by American Association for the Advancement of Science
Intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of asthma
CD Wegner,
RH Gundel,
P Reilly,
N Haynes,
LG Letts,
and
R Rothlein
Department of Pharmacology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877.
Airway eosinophilia, epithelial desquamation, and hyperresponsiveness are characteristics of the airway inflammation underlying bronchial asthma. The contribution of intercellular adhesion molecule-1 (ICAM-1) to eosinophil migration and airway responsiveness was studied. ICAM-1 partially mediated eosinophil adhesion to to endothelium in vitro and was upregulated on inflamed bronchial endothelium in vivo. ICAM-1 expression was also upregulated on inflamed airway epithelium in vitro and in vivo. In a primate model of asthma, a monoclonal antibody to ICAM-1 attenuated airway eosinophilia and hyperresponsiveness. Thus, antagonism of ICAM-1 may provide a therapeutic approach to reducing airway inflammation, hyperresponsiveness, and asthma symptoms.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Transepithelial Migration of Neutrophils: Mechanisms and Implications for Acute Lung Injury.
- R. L. Zemans, S. P. Colgan, and G. P. Downey (2009)
Am. J. Respir. Cell Mol. Biol.
40, 519-535
| Abstract »
| Full Text »
| PDF »
- Adenovirus E1A regulates lung epithelial ICAM-1 expression by interacting with transcriptional regulators at its promoter.
- K. Morimoto, J. Gosselink, A. Kartono, J. C. Hogg, S. Hayashi, and E. Ogawa (2009)
Am J Physiol Lung Cell Mol Physiol
296, L361-L371
| Abstract »
| Full Text »
| PDF »
- Neutrophils in cystic fibrosis.
- D G Downey, S C Bell, and J S Elborn (2009)
Thorax
64, 81-88
| Abstract »
| Full Text »
| PDF »
- Diminished ICAM-1 Expression and Impaired Pulmonary Clearance of Nontypeable Haemophilus influenzae in a Mouse Model of Chronic Obstructive Pulmonary Disease/Emphysema.
- B. Pang, W. Hong, S. L. West-Barnette, N. D. Kock, and W. E. Swords (2008)
Infect. Immun.
76, 4959-4967
| Abstract »
| Full Text »
| PDF »
- Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after {beta}2-Integrin Adhesion.
- X. Zhu, E. Boetticher, L. Wang, Y. Duan, J. Learoyd, and A. R. Leff (2008)
Am. J. Respir. Cell Mol. Biol.
39, 263-269
| Abstract »
| Full Text »
| PDF »
- Cross-Talk between ICAM-1 and GM-CSF Receptor Signaling Modulates Eosinophil Survival and Activation.
- K. Pazdrak, T. W. Young, S. Stafford, B. Olszewska-Pazdrak, C. Straub, V. Starosta, A. Brasier, and A. Kurosky (2008)
J. Immunol.
180, 4182-4190
| Abstract »
| Full Text »
| PDF »
- Is Airway Smooth Muscle the "Missing Link" Modulating Airway Inflammation in Asthma?.
- O. Tliba, Y. Amrani, and R. A. Panettieri Jr (2008)
Chest
133, 236-242
| Abstract »
| Full Text »
| PDF »
- Inhibition of phosphoinositide 3-kinase {delta} attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model.
- K. S. Lee, H. K. Lee, J. S. Hayflick, Y. C. Lee, and K. D. Puri (2006)
FASEB J
20, 455-465
| Abstract »
| Full Text »
| PDF »
- TNF-Related Activation-Induced Cytokine Enhances Leukocyte Adhesiveness: Induction of ICAM-1 and VCAM-1 via TNF Receptor-Associated Factor and Protein Kinase C-Dependent NF-{kappa}B Activation in Endothelial Cells.
- J.-K. Min, Y.-M. Kim, S. W. Kim, M.-C. Kwon, Y.-Y. Kong, I. K. Hwang, M. H. Won, J. Rho, and Y.-G. Kwon (2005)
J. Immunol.
175, 531-540
| Abstract »
| Full Text »
| PDF »
- Nonhuman primate models of asthma.
- R. L. Coffman and E. M. Hessel (2005)
J. Exp. Med.
201, 1875-1879
| Abstract »
| Full Text »
| PDF »
- A3 Adenosine Receptor Signaling Contributes to Airway Inflammation and Mucus Production in Adenosine Deaminase-Deficient Mice.
- H. W. J. Young, J. G. Molina, D. Dimina, H. Zhong, M. Jacobson, L.-N. L. Chan, T.-S. Chan, J. J. Lee, and M. R. Blackburn (2004)
J. Immunol.
173, 1380-1389
| Abstract »
| Full Text »
| PDF »
- Inflammatory Responses in Allergic Rhinitis: Traditional Approaches and Novel Treatment Strategies.
- S. A. Quraishi, M. J. Davies, and T. J. Craig (2004)
J Am Osteopath Assoc
104, 7S-15S
| Abstract »
| Full Text »
| PDF »
- Additive blockade of {beta}2-integrin adhesion of eosinophils by salmeterol and fluticasone propionate.
- S. Myo, X. Zhu, S. Myou, A.Y. Meliton, J. Liu, E. Boetticher, A.T. Lambertino, C. Xu, N.M. Munoz, and A.R. Leff (2004)
Eur. Respir. J.
23, 511-517
| Abstract »
| Full Text »
| PDF »
- Regulation of Leukocyte Transmigration: Cell Surface Interactions and Signaling Events.
- Y. Liu, S. K. Shaw, S. Ma, L. Yang, F. W. Luscinskas, and C. A. Parkos (2004)
J. Immunol.
172, 7-13
| Full Text »
| PDF »
- A Monoclonal Antibody to {alpha}1{beta}1 Blocks Antigen-induced Airway Responses in Sheep.
- W. M. Abraham, A. Ahmed, I. Serebriakov, A. N. Carmillo, J. Ferrant, A. R. de Fougerolles, E. A. Garber, P. J. Gotwals, V. E. Koteliansky, F. Taylor, et al. (2004)
Am. J. Respir. Crit. Care Med.
169, 97-104
| Abstract »
| Full Text »
| PDF »
- Inflammatory cytokines can enhance CD44-mediated airway epithelial cell adhesion independently of CD44 expression.
- S.-H. Leir, S. T. Holgate, and P. M. Lackie (2003)
Am J Physiol Lung Cell Mol Physiol
285, L1305-L1311
| Abstract »
| Full Text »
| PDF »
- Endothelial cells modulate eosinophil surface markers and mediator release.
- M-J. Dallaire, C. Ferland, N. Page, S. Lavigne, F. Davoine, and M. Laviolette (2003)
Eur. Respir. J.
21, 918-924
| Abstract »
| Full Text »
| PDF »
- Platelets Promote Eosinophil Adhesion of Patients with Asthma to Endothelium under Flow Conditions.
- L. H. Ulfman, D. P. H. Joosten, C. W. van Aalst, J.-W. J. Lammers, E. A. van de Graaf, L. Koenderman, and J. J. Zwaginga (2003)
Am. J. Respir. Cell Mol. Biol.
28, 512-519
| Abstract »
| Full Text »
| PDF »
- c-Src-dependent Tyrosine Phosphorylation of IKKbeta Is Involved in Tumor Necrosis Factor-alpha -induced Intercellular Adhesion Molecule-1 Expression.
- W.-C. Huang, J.-J. Chen, and C.-C. Chen (2003)
J. Biol. Chem.
278, 9944-9952
| Abstract »
| Full Text »
| PDF »
- Oral N-acetylcysteine attenuates the rat pulmonary inflammatory response to antigen.
- S. Blesa, J. Cortijo, M. Mata, A. Serrano, D. Closa, F. Santangelo, J.M. Estrela, J. Suchankova, and E.J. Morcillo (2003)
Eur. Respir. J.
21, 394-400
| Abstract »
| Full Text »
| PDF »
- Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1.
- E. Ohga, T. Tomita, H. Wada, H. Yamamoto, T. Nagase, and Y. Ouchi (2003)
J Appl Physiol
94, 179-184
| Abstract »
| Full Text »
| PDF »
- Recombinant alpha 1-proteinase inhibitor blocks antigen- and mediator-induced airway responses in sheep.
- M. Scuri, Y. Botvinnikova, I. T. Lauredo, and W. M. Abraham (2002)
J Appl Physiol
93, 1900-1906
| Abstract »
| Full Text »
| PDF »
- Functional Expression and Characterization of Macaque C-C Chemokine Receptor 3 (CCR3) and Generation of Potent Antagonistic Anti-macaque CCR3 Monoclonal Antibodies.
- L. Zhang, M. P. Soares, Y. Guan, S. Matheravidathu, R. Wnek, K. E. Johnson, A. Meisher, S. A. Iliff, J. S. Mudgett, M. S. Springer, et al. (2002)
J. Biol. Chem.
277, 33799-33810
| Abstract »
| Full Text »
| PDF »
- Blockade of Focal Clustering and Active Conformation in {beta}2-Integrin-Mediated Adhesion of Eosinophils to Intercellular Adhesion Molecule-1 Caused by Transduction of HIV TAT-Dominant Negative Ras.
- S. Myou, X. Zhu, E. Boetticher, S. Myo, A. Meliton, A. Lambertino, N. M. Munoz, and A. R. Leff (2002)
J. Immunol.
169, 2670-2676
| Abstract »
| Full Text »
| PDF »
- Role of alveolar epithelial ICAM-1 in lipopolysaccharide-induced lung inflammation.
- B. Beck-Schimmer, C. Madjdpour, S. Kneller, U. Ziegler, T. Pasch, R.P. Wuthrich, P.A. Ward, and R.C. Schimmer (2002)
Eur. Respir. J.
19, 1142-1150
| Abstract »
| Full Text »
| PDF »
- Fast Flowing Eosinophils . Signals for Stopping and Stepping Out of Blood Vessels.
- D. Broide (2002)
Am. J. Respir. Cell Mol. Biol.
26, 637-640
| Full Text »
| PDF »
- Interferon-gamma -induced Epithelial ICAM-1 Expression and Monocyte Adhesion. INVOLVEMENT OF PROTEIN KINASE C-DEPENDENT c-Src TYROSINE KINASE ACTIVATION PATHWAY.
- Y.-J. Chang, M. J. Holtzman, and C.-C. Chen (2002)
J. Biol. Chem.
277, 7118-7126
| Abstract »
| Full Text »
| PDF »
- Stimulant-Dependent Modulation of Cytokines and Chemokines by Airway Epithelial Cells: Cross Talk between Pulmonary Epithelial and Peripheral Blood Mononuclear Cells.
- T. Krakauer (2002)
Clin. Vaccine Immunol.
9, 126-131
| Abstract »
| Full Text »
| PDF »
- Immunity, Inflammation, and Remodeling in the Airway Epithelial Barrier: Epithelial-Viral-Allergic Paradigm.
- M. J. Holtzman, J. D. Morton, L. P. Shornick, J. W. Tyner, M. P. O'Sullivan, A. Antao, M. Lo, M. Castro, and M. J. Walter (2002)
Physiol Rev
82, 19-46
| Abstract »
| Full Text »
| PDF »
- Vessels: new targets for asthma treatment.
- J W WILSON and X LI (2001)
Thorax
56, 899-900
| Full Text »
| PDF »
- Eosinophil Tissue Recruitment to Sites of Allergic Inflammation in the Lung Is Platelet Endothelial Cell Adhesion Molecule Independent.
- M. Miller, K.-L. P. Sung, W. A. Muller, J. Y. Cho, M. Roman, D. Castaneda, J. Nayar, T. Condon, J. Kim, P. Sriramarao, et al. (2001)
J. Immunol.
167, 2292-2297
| Abstract »
| Full Text »
| PDF »
- Interferon-gamma Stimulates Fractalkine Expression in Human Bronchial Epithelial Cells and Regulates Mononuclear Cell Adherence.
- K. Fujimoto, T. Imaizumi, H. Yoshida, S. Takanashi, K. Okumura, and K. Satoh (2001)
Am. J. Respir. Cell Mol. Biol.
25, 233-238
| Abstract »
| Full Text »
| PDF »
- Distinct Roles for PECAM-1, ICAM-1, and VCAM-1 in Recruitment of Neutrophils and Eosinophils to the Cornea in Ocular Onchocerciasis (River Blindness).
- J. T. Kaifi, E. Diaconu, and E. Pearlman (2001)
J. Immunol.
166, 6795-6801
| Abstract »
| Full Text »
| PDF »
- Mechanism of cooperative effects of rhinovirus and atopic sensitization on airway responsiveness.
- M. M. Grunstein, H. Hakonarson, R. L. Hodinka, N. Maskeri, C. Kim, and S. Chuang (2001)
Am J Physiol Lung Cell Mol Physiol
280, L229-L238
| Abstract »
| Full Text »
| PDF »
- Role of leukotrienes in bronchial hyperresponsiveness and cellular responses in airways.
- A. R Leff (2000)
Thorax
55, 32S-37
| Full Text »
- Soluble Intercellular Adhesion Molecule-1 (sICAM-1) and Interferon-Gamma in Bronchoalveolar Lavage Fluid from Children with Airway Diseases.
- C. MARGUET, T. P. DEAN, and J. O. WARNER (2000)
Am. J. Respir. Crit. Care Med.
162, 1016-1022
| Abstract »
| Full Text »
- Effects of TNF-alpha on Expression of ICAM-1 in Human Airway Epithelial Cells In Vitro . Signaling Pathways Controlling Surface and Gene Expression.
- T. M. Krunkosky, B. M. Fischer, L. D. Martin, N. Jones, N. J. Akley, and K. B. Adler (2000)
Am. J. Respir. Cell Mol. Biol.
22, 685-692
| Abstract »
| Full Text »
- Increased CD44 expression in human bronchial epithelial repair after damage or plating at low cell densities.
- S.-H. Leir, J. E. Baker, S. T. Holgate, and P. M. Lackie (2000)
Am J Physiol Lung Cell Mol Physiol
278, L1129-L1137
| Abstract »
| Full Text »
| PDF »
- Intrinsic ICAM-1/LFA-1 activation mediates altered responsiveness of atopic asthmatic airway smooth muscle.
- M. M. Grunstein, H. Hakonarson, N. Maskeri, C. Kim, and S. Chuang (2000)
Am J Physiol Lung Cell Mol Physiol
278, L1154-L1163
| Abstract »
| Full Text »
| PDF »
- Role of Leukotrienes in Bronchial Hyperresponsiveness and Cellular Responses in Airways.
- A. R. LEFF (2000)
Am. J. Respir. Crit. Care Med.
161, S125-132
| Full Text »
| PDF »
- Neutrophils enhance clearance of necrotic epithelial cells in ozone-induced lung injury in rhesus monkeys.
- D. M. Hyde, L. A. Miller, R. J. McDonald, M. Y. Stovall, V. Wong, K. E. Pinkerton, C. D. Wegner, R. Rothlein, and C. G. Plopper (1999)
Am J Physiol Lung Cell Mol Physiol
277, L1190-L1198
| Abstract »
| Full Text »
| PDF »
- Eosinophilic arthritis.
- C.-H. Tay (1999)
Rheumatology
38, 1188-1194
| Abstract »
| Full Text »
| PDF »
- Cytosolic Phospholipase A2 Activation Is Essential for {beta}1 and {beta}2 Integrin-Dependent Adhesion of Human Eosinophils.
- X. Zhu, N. M. Munoz, K. P. Kim, H. Sano, W. Cho, and A. R. Leff (1999)
J. Immunol.
163, 3423-3429
| Abstract »
| Full Text »
| PDF »
- Picornavirus Receptor Down-Regulation by Plasminogen Activator Inhibitor Type 2.
- D. R. Shafren, J. Gardner, V. H. Mann, T. M. Antalis, and A. Suhrbier (1999)
J. Virol.
73, 7193-7198
| Abstract »
| Full Text »
- Up-Regulation of ICAM-1 by Cytokines in Human Tracheal Smooth Muscle Cells Involves an NF-{kappa}B-Dependent Signaling Pathway That Is Only Partially Sensitive to Dexamethasone.
- Y. Amrani, A. L. Lazaar, and R. A. Panettieri Jr. (1999)
J. Immunol.
163, 2128-2134
| Abstract »
| Full Text »
| PDF »
- Increased levels of circulating ICAM-1, VCAM-1, and L-selectin in obstructive sleep apnea syndrome.
- E. Ohga, T. Nagase, T. Tomita, S. Teramoto, T. Matsuse, H. Katayama, and Y. Ouchi (1999)
J Appl Physiol
87, 10-14
| Abstract »
| Full Text »
| PDF »
- Rhinovirus-mediated changes in airway smooth muscle responsiveness: induced autocrine role of interleukin-1beta.
- H. Hakonarson, C. Carter, N. Maskeri, R. Hodinka, and M. M. Grunstein (1999)
Am J Physiol Lung Cell Mol Physiol
277, L13-L21
| Abstract »
| Full Text »
| PDF »
- IL-4 induces ICAM-1 expression in human bronchial epithelial cells and potentiates TNF-alpha.
- I. Striz, T. Mio, Y. Adachi, P. Heires, R. A. Robbins, J. R. Spurzem, M. J. Illig, D. J. Romberger, and S. I. Rennard (1999)
Am J Physiol Lung Cell Mol Physiol
277, L58-L64
| Abstract »
| Full Text »
| PDF »
- Characterization of Eosinophil Adhesion to TNF-{alpha}-Activated Endothelium Under Flow Conditions: {alpha}4 Integrins Mediate Initial Attachment, and E-Selectin Mediates Rolling.
- L. H. Ulfman, P. H. M. Kuijper, J. A. M. van der Linden, J.-W. J. Lammers, J. J. Zwaginga, and L. Koenderman (1999)
J. Immunol.
163, 343-350
| Abstract »
| Full Text »
| PDF »
- Rhinovirus Infection Induces Expression of Its Own Receptor Intercellular Adhesion Molecule 1 (ICAM-1) via Increased NF-kappa B-mediated Transcription.
- A. Papi and S. L. Johnston (1999)
J. Biol. Chem.
274, 9707-9720
| Abstract »
| Full Text »
| PDF »
- Selectin Blockade Prevents Antigen-induced Late Bronchial Responses and Airway Hyperresponsiveness in Allergic Sheep.
- W. M. ABRAHAM, A. AHMED, J. R. SABATER, I. T. LAUREDO, Y. BOTVINNIKOVA, R. J. BJERCKE, X. HU, B. M. REVELLE, T. P. KOGAN, I. L. SCOTT, et al. (1999)
Am. J. Respir. Crit. Care Med.
159, 1205-1214
| Abstract »
| Full Text »
| PDF »
- Differential Effects of Endogenous and Exogenous Interferon-gamma on Immunoglobulin E, Cellular Infiltration, and Airway Responsiveness in a Murine Model of Allergic Asthma.
- C. L. Hofstra, I. Van Ark, G. Hofman, F. P. Nijkamp, P. M. Jardieu, and A. J. M. Van Oosterhout (1998)
Am. J. Respir. Cell Mol. Biol.
19, 826-835
| Abstract »
| Full Text »
- Increased Endothelial Cell Expression of Platelet-Endothelial Cell Adhesion Molecule-1 during Hyperoxic Lung Injury.
- B. Piedboeuf, M. Gamache, J. Frenette, S. Horowitz, H. Scott Baldwin, and P. Petrov (1998)
Am. J. Respir. Cell Mol. Biol.
19, 543-553
| Abstract »
| Full Text »
- A CD18/ICAM-1-dependent Pathway Mediates Eosinophil Adhesion to Human Bronchial Epithelial Cells.
- A. Burke-Gaffney and P. G. Hellewell (1998)
Am. J. Respir. Cell Mol. Biol.
19, 408-418
| Abstract »
| Full Text »
- Involvement of Lymphocyte Function-Associated Antigen-1 and Intercellular Adhesion Molecule-1 in Osteoclastogenesis: A Possible Role in Direct Interaction between Osteoclast Precursors.
- H. Harada, T. Kukita, A. Kukita, Y. Iwamoto, and T. Iijima (1998)
Endocrinology
139, 3967-3975
| Abstract »
| Full Text »
| PDF »
- Differential Regulation of Eosinophil Adhesion and Transmigration by Pulmonary Microvascular Endothelial Cells.
- H. Yamamoto, J. B. Sedgwick, and W. W. Busse (1998)
J. Immunol.
161, 971-977
| Abstract »
| Full Text »
| PDF »
- Granulocyte Macrophage Colony-stimulating Factor Augments ICAM-1 and VCAM-1 Activation of Eosinophil Function.
- M. Nagata, J. B. Sedgwick, H. Kita, and W. W. Busse (1998)
Am. J. Respir. Cell Mol. Biol.
19, 158-166
| Abstract »
| Full Text »
- Effects of Rhinovirus Infection on Hydrogen Peroxide- induced Alterations of Barrier Function in the Cultured Human Tracheal Epithelium.
- T. OHRUI, M. YAMAYA, K. SEKIZAWA, N. YAMADA, T. SUZUKI, M. TERAJIMA, S. OKINAGA, and H. SASAKI (1998)
Am. J. Respir. Crit. Care Med.
158, 241-248
| Abstract »
| Full Text »
| PDF »
- Reduction of Antigen-induced Airway Hyperreactivity and Eosinophilia in ICAM-1-deficient Mice.
- W. W. Wolyniec, G. T. De Sanctis, G. Nabozny, C. Torcellini, N. Haynes, A. Joetham, E. W. Gelfand, J. M. Drazen, and T. C. Noonan (1998)
Am. J. Respir. Cell Mol. Biol.
18, 777-785
| Abstract »
| Full Text »
- Eosinophilia.
- M. E. Rothenberg (1998)
N. Engl. J. Med.
338, 1592-1600
| Full Text »
| PDF »
- Respiratory Syncytial Virus-Infected Pulmonary Epithelial Cells Induce Eosinophil Degranulation by a CD18-Mediated Mechanism.
- B. Olszewska-Pazdrak, K. Pazdrak, P. L. Ogra, and R. P. Garofalo (1998)
J. Immunol.
160, 4889-4895
| Abstract »
| Full Text »
| PDF »
- Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity.
- S. Koyama, E. Sato, H. Nomura, K. Kubo, S. Nagai, and T. Izumi (1998)
J Appl Physiol
84, 1528-1534
| Abstract »
| Full Text »
| PDF »
- Inhibition of Eosinophil Rolling and Recruitment in P-Selectin- and Intracellular Adhesion Molecule-1-Deficient Mice.
- D. H. Broide, D. Humber, and P. Sriramarao (1998)
Blood
91, 2847-2856
| Abstract »
| Full Text »
| PDF »
- Circulating Adhesion Molecules in Cystic Fibrosis.
- V. DE ROSE, A. OLIVA, B. MESSORE, B. GROSSO, C. MOLLAR, and E. POZZI (1998)
Am. J. Respir. Crit. Care Med.
157, 1234-1239
| Abstract »
| Full Text »
| PDF »
- Asthma.
- J. A. NADEL and W. W. BUSSE (1998)
Am. J. Respir. Crit. Care Med.
157, S130-S138
| Full Text »
| PDF »
- Human Eotaxin Induces {alpha}4 and {beta}2 Integrin-Dependent Eosinophil Accumulation in Rat Skin In Vivo: Delayed Generation of Eotaxin in Response to IL-4.
- M.-J. Sanz, P. D. Ponath, C. R. Mackay, W. Newman, M. Miyasaka, T. Tamatani, B. F. Flanagan, R. R. Lobb, T. J. Williams, S. Nourshargh, et al. (1998)
J. Immunol.
160, 3569-3576
| Abstract »
| Full Text »
| PDF »
- Regulation of Allergic Inflammation and Eosinophil Recruitment in Mice Lacking the Transcription Factor NFAT1: Role of Interleukin-4 (IL-4) and IL-5.
- J. P.B. Viola, A. Kiani, P. T. Bozza, and A. Rao (1998)
Blood
91, 2223-2230
| Abstract »
| Full Text »
| PDF »
- Essential Roles of NF-kappa B and C/EBP in the Regulation of Intercellular Adhesion Molecule-1 after Respiratory Syncytial Virus Infection of Human Respiratory Epithelial Cell Cultures.
- B. A. Chini, M. A. Fiedler, L. Milligan, T. Hopkins, and J. M. Stark (1998)
J. Virol.
72, 1623-1626
| Abstract »
| Full Text »
| PDF »
- Involvement of Intercellular Adhesion Molecule-1 in the Antigen-induced Infiltration of Eosinophils and Lymphocytes into the Airways in a Murine Model of Pulmonary Inflammation.
- J. E. Chin, G. E. Winterrowd, C. A. Hatfield, J. R. Brashler, R. L. Griffin, S. L. Vonderfecht, K. P. Kolbasa, S. F. Fidler, K. L. Shull, R. F. Krzesicki, et al. (1998)
Am. J. Respir. Cell Mol. Biol.
18, 158-167
| Abstract »
| Full Text »
- Inhibition of Pulmonary Eosinophilia in P-Selectin- and ICAM-1-deficient Mice.
- D. H. Broide, S. Sullivan, T. Gifford, and P. Sriramarao (1998)
Am. J. Respir. Cell Mol. Biol.
18, 218-225
| Abstract »
| Full Text »
- Allergen Exposure Induces the Expression of Endothelial Adhesion Molecules in Passively Sensitized Human Bronchus: Time Course and the Role of Cytokines.
- N. Hirata, H. Kohrogi, H. Iwagoe, E. Goto, J. Hamamoto, K. Fujii, T. Yamaguchi, O. Kawano, and M. Ando (1998)
Am. J. Respir. Cell Mol. Biol.
18, 12-20
| Abstract »
| Full Text »
- Clinical Role of Soluble Adhesion Molecules During Immunotherapy for Perennial Allergic Rhinitis.
- Y. Ohashi, Y. Nakai, A. Tanaka, Y. Kakinoki, Y. Ohno, T. Masamoto, H. Sakamoto, A. Kato, Y. Washio, K. Yamada, et al. (1998)
Arch Otolaryngol Head Neck Surg
124, 41-45
| Abstract »
| Full Text »
| PDF »
- Immunopharmacology: Immunomodulation and Immunotherapy.
- M. Ballow and R. Nelson (1997)
JAMA
278, 2008-2017
| Abstract »
| PDF »
- Pneumocystis carinii induces ICAM-1 expression in lung epithelial cells through a TNF-alpha -mediated mechanism.
- M. L. Yu and A. H. Limper (1997)
Am J Physiol Lung Cell Mol Physiol
273, L1103-L1111
| Abstract »
| Full Text »
| PDF »
- Determination of airway and tissue resistances after antigen and methacholine in nonhuman primates.
- J. B. Madwed and A. C. Jackson (1997)
J Appl Physiol
83, 1690-1696
| Abstract »
| Full Text »
| PDF »
- Phenotyping and Cytokine Regulation of the BEAS-2B Human Bronchial Epithelial Cell: Demonstration of Inducible Expression of the Adhesion Molecules VCAM-1 and ICAM-1.
- J. Atsuta, S. A. Sterbinsky, J. Plitt, L. M. Schwiebert, B. S. Bochner, and R. P. Schleimer (1997)
Am. J. Respir. Cell Mol. Biol.
17, 571-582
| Abstract »
| Full Text »
- Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1beta.
- M. Terajima, M. Yamaya, K. Sekizawa, S. Okinaga, T. Suzuki, N. Yamada, K. Nakayama, T. Ohrui, T. Oshima, Y. Numazaki, et al. (1997)
Am J Physiol Lung Cell Mol Physiol
273, L749-L759
| Abstract »
| Full Text »
| PDF »
- Phase I Safety and Pharmacokinetic Profile of an Intercellular Adhesion Molecule-1 Antisense Oligodeoxynucleotide (ISIS 2302).
- J. M. Glover, J. M. Leeds, T. G. K. Mant, D. Amin, D. L. Kisner, J. E. Zuckerman, R. S. Geary, A. A. Levin, and W. R. Shanahan Jr. (1997)
J. Pharmacol. Exp. Ther.
282, 1173-1180
| Abstract »
| Full Text »
- PGE1, dexamethasone, U-74389G, or Bt2-cAMP as an additive to promote protection by UW solution in I/R injury.
- C.-H. Chiang, K. Hsu, H.-C. Yan, H.-J. Harn, and D.-M. Chang (1997)
J Appl Physiol
83, 583-590
| Abstract »
| Full Text »
| PDF »
- Immunological responses to respiratory syncytial virus infection in infancy.
- R L Smyth, J N Fletcher, H M Thomas, and C A Hart (1997)
Arch. Dis. Child.
76, 210-214
| Abstract »
| Full Text »
- An ICAM-1 Antisense Oligonucleotide Prevents and Reverses Dextran Sulfate Sodium-Induced Colitis in Mice.
- C. F. Bennett, D. Kornbrust, S. Henry, K. Stecker, R. Howard, S. Cooper, S. Dutson, W. Hall, and H. I. Jacoby (1997)
J. Pharmacol. Exp. Ther.
280, 988-1000
| Abstract »
| Full Text »
- Inhibition of Stimulus-Induced Endothelial Cell Intercellular Adhesion Molecule-1, E-Selectin, and Vascular Cellular Adhesion Molecule-1 Expression by Arachidonic Acid and Its Hydroxy and Hydroperoxy Derivatives.
- Z. H. Huang, E. J. Bates, J. V. Ferrante, C. S.T. Hii, A. Poulos, B. S. Robinson, and A. Ferrante (1997)
Circ. Res.
80, 149-158
| Abstract »
| Full Text »
- Cell Adhesion Molecules in Inflammation and Immunity: Relevance to Periodontal Diseases.
- J. M. Crawford and K. Watanabe (1994)
Critical Reviews in Oral Biology & Medicine
5, 91-123
| Abstract »
| Full Text »
| PDF »
- Eosinophilic Pustular Folliculitis (Ofuji's Disease) Immunohistochemical Analysis.
- Y. Teraki, I. Konohana, T. Shiohara, M. Nagashima, and T. Nishikawa (1993)
Arch Dermatol
129, 1015-1019
| Abstract »
| PDF »
- New Concepts about the Mast Cell.
- S. J. Galli (1993)
N. Engl. J. Med.
328, 257-265
| Full Text »
- Cytokine-Induced Changes in the Leukon.
- T. D. Anderson (1993)
Toxicol Pathol
21, 147-157
| Abstract »
| PDF »
- Rhinitis and Asthma.
- M. Kaliner and R. Lemanske (1992)
JAMA
268, 2807-2829
| Abstract »
| PDF »
- AN ADHESION MOLECULE MAY PLAY A CENTRAL ROLE IN ASTHMA.
- (1990)
Journal Watch (General)
1990, 4
| Full Text »
|
|