Science 11 August 1989: Vol. 245. no. 4918, pp. 646 - 648 DOI: 10.1126/science.2503872

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Articles

Saccharomyces cerevisiae septins: Supramolecular organization of heterooligomers and the mechanism of filament assembly.

A. Bertin, M. A. McMurray, P. Grob, S.-S. Park, G. Garcia III, I. Patanwala, H.-l. Ng, T. Alber, J. Thorner, and E. Nogales (2008)
PNAS 105, 8274-8279
 |  Abstract »  |  Full Text »  |  PDF »

Glycoprotein Ib{alpha} forms disulfide bonds with 2 glycoprotein Ib{beta} subunits in the resting platelet.

S.-Z. Luo, X. Mo, V. Afshar-Kharghan, S. Srinivasan, J. A. Lopez, and R. Li (2007)
Blood 109, 603-609
 |  Abstract »  |  Full Text »  |  PDF »

Protein-protein interaction analysis by C-terminally specific fluorescence labeling and fluorescence cross-correlation spectroscopy.

R. Oyama, H. Takashima, M. Yonezawa, N. Doi, E. Miyamoto-Sato, M. Kinjo, and H. Yanagawa (2006)
Nucleic Acids Res. 34, e102
 |  Abstract »  |  Full Text »  |  PDF »

Forced Dimerization of gp130 Leads to Constitutive STAT3 Activation, Cytokine-independent Growth, and Blockade of Differentiation of Embryonic Stem Cells.

C. Stuhlmann-Laeisz, S. Lang, A. Chalaris, P. Krzysztof, S. Enge, J. Eichler, U. Klingmuller, M. Samuel, M. Ernst, S. Rose-John, et al. (2006)
Mol. Biol. Cell 17, 2986-2995
 |  Abstract »  |  Full Text »  |  PDF »

CytLEK1 Is a Regulator of Plasma Membrane Recycling through Its Interaction with SNAP-25.

R. D. Pooley, S. Reddy, V. Soukoulis, J. T. Roland, J. R. Goldenring, and D. M. Bader (2006)
Mol. Biol. Cell 17, 3176-3186
 |  Abstract »  |  Full Text »  |  PDF »

Semirational design of Jun-Fos coiled coils with increased affinity: Universal implications for leucine zipper prediction and design.

J. M. Mason, M. A. Schmitz, K. M. Muller, and K. M. Arndt (2006)
PNAS 103, 8989-8994
 |  Abstract »  |  Full Text »  |  PDF »

A ToxR-based two-hybrid system for the detection of periplasmic and cytoplasmic protein-protein interactions in Escherichia coli: minimal requirements for specific DNA binding and transcriptional activation.

F. Hennecke, A. Muller, R. Meister, A. Strelow, and S. Behrens (2005)
Protein Eng. Des. Sel. 18, 477-486
 |  Abstract »  |  Full Text »  |  PDF »

Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway.

V. Soukoulis, S. Reddy, R. D. Pooley, Y. Feng, C. A. Walsh, and D. M. Bader (2005)
PNAS 102, 8549-8554
 |  Abstract »  |  Full Text »  |  PDF »

Forcing interactions as a genetic screen to identify proteins that exert a defined activity.

M. DeVit, P. J. Cullen, M. Branson, G. F. Sprague Jr., and S. Fields (2005)
Genome Res. 15, 560-565
 |  Abstract »  |  Full Text »  |  PDF »

Biophysical and Mutational Analysis of the Putative bZIP Domain of Epstein-Barr Virus EBNA 3C.

M. J. West, H. M. Webb, A. J. Sinclair, and D. N. Woolfson (2004)
J. Virol. 78, 9431-9445
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Transmembrane Domain 2 of Rat Serotonin Transporter by Cysteine Scanning Mutagenesis.

Y. Sato, Y.-W. Zhang, A. Androutsellis-Theotokis, and G. Rudnick (2004)
J. Biol. Chem. 279, 22926-22933
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Chromosomal Binding Sites and Dimerization Partners of the Viral Oncoprotein Meq in Marek's Disease Virus-Transformed T Cells.

A. M. Levy, Y. Izumiya, P. Brunovskis, L. Xia, M. S. Parcells, S. M. Reddy, L. Lee, H.-W. Chen, and H.-J. Kung (2003)
J. Virol. 77, 12841-12851
 |  Abstract »  |  Full Text »  |  PDF »

Determination of membrane protein stability via thermodynamic coupling of folding to thiol-disulfide interchange.

L. Cristian, J. D. Lear, and W. F. DeGrado (2003)
Protein Sci. 12, 1732-1740
 |  Abstract »  |  Full Text »  |  PDF »

Mutations within an Intramembrane Leucine Heptad Repeat Disrupt Oligomer Formation of the Rat GABA Transporter 1.

P. Scholze, M. Freissmuth, and H. H. Sitte (2002)
J. Biol. Chem. 277, 43682-43690
 |  Abstract »  |  Full Text »  |  PDF »

The role of helix stabilizing residues in GCN4 basic region folding and DNA binding.

J. J. Hollenbeck, D. L. McClain, and M. G. Oakley (2002)
Protein Sci. 11, 2740-2747
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Heterophilic and Homophilic Interactions of Cadherins Using the c-Jun/c-Fos Dimerization Domains.

T. Ahrens, O. Pertz, D. Haussinger, C. Fauser, T. Schulthess, and J. Engel (2002)
J. Biol. Chem. 277, 19455-19460
 |  Abstract »  |  Full Text »  |  PDF »

Role of Interfacial Hydrophobic Residues in the Stabilization of the Leucine Zipper Structures of the Transcription Factors c-Fos and c-Jun.

R. I. Boysen, A. J. O. Jong, J. A. Wilce, G. F. King, and M. T. W. Hearn (2002)
J. Biol. Chem. 277, 23-31
 |  Abstract »  |  Full Text »

Structure-Function Analysis of the Heat Shock Factor-binding Protein Reveals a Protein Composed Solely of a Highly Conserved and Dynamic Coiled-coil Trimerization Domain.

L.-J. Tai, S. M. McFall, K. Huang, B. Demeler, S. G. Fox, K. Brubaker, I. Radhakrishnan, and R. I. Morimoto (2002)
J. Biol. Chem. 277, 735-745
 |  Abstract »  |  Full Text »

pH-induced folding of an apoptotic coiled coil.

K. Dutta, A. Alexandrov, H. Huang, and S. M. Pascal (2001)
Protein Sci. 10, 2531-2540
 |  Abstract »  |  Full Text »  |  PDF »

Polyionic fusion peptides function as specific dimerization motifs.

S. A. Richter, K. Stubenrauch, H. Lilie, and R. Rudolph (2001)
Protein Eng. Des. Sel. 14, 775-783
 |  Abstract »  |  Full Text »  |  PDF »

Rap1p Requires Gcr1p and Gcr2p Homodimers to Activate Ribosomal Protein and Glycolytic Genes, Respectively.

S. J. Deminoff and G. M. Santangelo (2001)
Genetics 158, 133-143
 |  Abstract »  |  Full Text »

From the Cover: A computationally directed screen identifying interacting coiled coils from Saccharomyces cerevisiae.

J. R. S. Newman, E. Wolf, and P. S. Kim (2000)
PNAS 97, 13203-13208
 |  Abstract »  |  Full Text »  |  PDF »

Site-directed ligand discovery.

D. A. Erlanson, A. C. Braisted, D. R. Raphael, M. Randal, R. M. Stroud, E. M. Gordon, and J. A. Wells (2000)
PNAS 97, 9367-9372
 |  Abstract »  |  Full Text »  |  PDF »

Electrostatic Interactions in Leucine Zippers: Effects on Stability and Specificity of Interaction.

K. P. McGrath, M. M. Butler, C. M. DiGirolamo, D. L. Kaplan, W. A. Petka, and T. M. Laue (2000)
Journal of Bioactive and Compatible Polymers 15, 334-356
 |  Abstract »  |  PDF »

Growth Hormone (GH)-independent Dimerization of GH Receptor by a Leucine Zipper Results in Constitutive Activation.

S. N. Behncken, N. Billestrup, R. Brown, J. Amstrup, B. Conway-Campbell, and M. J. Waters (2000)
J. Biol. Chem. 275, 17000-17007
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Homodimerization of Poly(ADP-ribose) Polymerase by Its C-terminal Cleavage Products Produced during Apoptosis.

J. W. Kim, K. Kim, K. Kang, and C. O. Joe (2000)
J. Biol. Chem. 275, 8121-8125
 |  Abstract »  |  Full Text »  |  PDF »

The Cloning and Analysis of LEK1 Identifies Variations in the LEK/Centromere Protein F/Mitosin Gene Family.

R. L. Goodwin, L. M. Pabon-Pena, G. C. Foster, and D. Bader (1999)
J. Biol. Chem. 274, 18597-18604
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Dimerization Domain in BglG, an RNA-Binding Transcriptional Antiterminator from Escherichia coli.

A. Boss, A. Nussbaum-Shochat, and O. Amster-Choder (1999)
J. Bacteriol. 181, 1755-1766
 |  Abstract »  |  Full Text »

Life without white fat: a transgenic mouse.

J. Moitra, M. M. Mason, M. Olive, D. Krylov, O. Gavrilova, B. Marcus-Samuels, L. Feigenbaum, E. Lee, T. Aoyama, M. Eckhaus, et al. (1998)
Genes & Dev. 12, 3168-3181
 |  Abstract »  |  Full Text »

A method for directed evolution and functional cloning of enzymes.

H. Pedersen, S. Holder, D. P. Sutherlin, U. Schwitter, D. S. King, and P. G. Schultz (1998)
PNAS 95, 10523-10528
 |  Abstract »  |  Full Text »  |  PDF »

cAMP Response Element-binding Protein Monomers Cooperatively Assemble to Form Dimers on DNA.

X. Wu, C. Spiro, W. G. Owen, and C. T. McMurray (1998)
J. Biol. Chem. 273, 20820-20827
 |  Abstract »  |  Full Text »  |  PDF »

Tenascin-C Hexabrachion Assembly Is a Sequential Two-step Process Initiated by Coiled-coil alpha -Helices.

R. A. Kammerer, T. Schulthess, R. Landwehr, A. Lustig, D. Fischer, and J. Engel (1998)
J. Biol. Chem. 273, 10602-10608
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Characterization of a cDNA That Encodes Six Isoforms of a Novel Murine A Kinase Anchor Protein.

F. Dong, M. Feldmesser, A. Casadevall, and C. S. Rubin (1998)
J. Biol. Chem. 273, 6533-6541
 |  Abstract »  |  Full Text »  |  PDF »

Buried asparagines determine the dimerization specificities of leucine zipper mutants.

X. Zeng, A. M. Herndon, and J. C. Hu (1997)
PNAS 94, 3673-3678
 |  Abstract »  |  Full Text »  |  PDF »

Functional Replacement of Cytokine Receptor Extracellular Domains by Leucine Zippers.

N. Patel, J. M. Herrman, J. C. Timans, and R. A. Kastelein (1996)
J. Biol. Chem. 271, 30386-30391
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Recombinant HLA-DR2 Molecules. REPLACEMENT OF THE HYDROPHOBIC TRANSMEMBRANE REGION BY A LEUCINE ZIPPER DIMERIZATION MOTIF ALLOWS THE ASSEMBLY AND SECRETION OF SOLUBLE DR alpha beta HETERODIMERS.

A. Kalandadze, M. Galleno, L. Foncerrada, J. L. Strominger, and K. W. Wucherpfennig (1996)
J. Biol. Chem. 271, 20156-20162
 |  Abstract »  |  Full Text »  |  PDF »

Leucine Zipper Dimerized Bivalent and Bispecific scFv Antibodies from a Semi-synthetic Antibody Phage Display Library.

J. de Kruif and T. Logtenberg (1996)
J. Biol. Chem. 271, 7630-7634
 |  Abstract »  |  Full Text »  |  PDF »

A Leucine Zipper Stabilizes the Pentameric Membrane Domain of Phospholamban and Forms a Coiled-coil Pore Structure.

H. K. B. Simmerman, Y. M. Kobayashi, J. M. Autry, and L. R. Jones (1996)
J. Biol. Chem. 271, 5941-5946
 |  Abstract »  |  Full Text »  |  PDF »

Response: How Much Solar Radiation Do Clouds Absorb?.

K. J. Lumb and P. S. Kim (1996)
Science 271, 1137-1138
 |  PDF »

Identification of a novel cardiac-specific transcript critical for cardiac myocyte differentiation.

Y Wei, D Bader, and J Litvin (1996)
Development 122, 2779-2789
 |  Abstract »  |  PDF »

The Effects of Interhelical Electrostatic Repulsions between Glutamic Acid Residues in Controlling the Dimerization and Stability of Two-stranded alpha-Helical Coiled-coils.

W. D. Kohn, O. D. Monera, C. M. Kay, and R. S. Hodges (1995)
J. Biol. Chem. 270, 25495-25506
 |  Abstract »  |  Full Text »  |  PDF »

Fos Leucine Zipper Variants with Increased Association Capacity.

D. Porte, P. Oertel-Buchheit, and M.čl. Granger-Schnarr (1995)
J. Biol. Chem. 270, 22721-22730
 |  Abstract »  |  Full Text »  |  PDF »

Physical Characterization of Calponin.

K. Mabuchi, K. Takahashi, and T. Tao (1995)
J. Biol. Chem. 270, 10576-10579
 |  Abstract »  |  Full Text »  |  PDF »

Repression of the c-Jun trans-Activation Function by the Adenovirus Type 12 E1A 52R Protein Correlates with the Inhibition of Phosphorylation of the c-Jun Activation Domain.

D. Brockmann, C. Bury, G. Kröner, H.-C. Kirch, and H. Esche (1995)
J. Biol. Chem. 270, 10754-10763
 |  Abstract »  |  Full Text »  |  PDF »

Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper.

K. Lumb and P. Kim (1995)
Science 268, 436-439
 |  Abstract »  |  PDF »

Hydrophobic coiled-coil domains regulate the subcellular localization of human heat shock factor 2..

L A Sheldon and R E Kingston (1993)
Genes & Dev. 7, 1549-1558
 |  Abstract »  |  PDF »

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design..

C R Vinson, T Hai, and S M Boyd (1993)
Genes & Dev. 7, 1047-1058
 |  Abstract »  |  PDF »

Crystal structure of a synthetic triple-stranded alpha-helical bundle.

B Lovejoy, S Choe, D Cascio, D. McRorie, W. DeGrado, and D Eisenberg (1993)
Science 259, 1288-1293
 |  Abstract »  |  PDF »

Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos.

M. Blanar and W. Rutter (1992)
Science 256, 1014-1018
 |  Abstract »  |  PDF »

Contrasting patterns of c-myc and N-myc expression in proliferating, quiescent, and differentiating cells of the embryonic chicken lens.

L. Harris, J. Talian, and P. Zelenka (1992)
Development 115, 813-820
 |  Abstract »  |  PDF »

X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil.

E. O'Shea, J. Klemm, P. Kim, and T Alber (1991)
Science 254, 539-544
 |  Abstract »  |  PDF »

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.

E. Blackwood and R. Eisenman (1991)
Science 251, 1211-1217
 |  Abstract »  |  PDF »

New light on Myc and Myb. Part I. Myc..

B Luscher and R N Eisenman (1990)
Genes & Dev. 4, 2025-2035
 |  PDF »

A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids.

K. O'Neil and W. DeGrado (1990)
Science 250, 646-651
 |  Abstract »  |  PDF »

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity..

Y F Hu, B Luscher, A Admon, N Mermod, and R Tjian (1990)
Genes & Dev. 4, 1741-1752
 |  Abstract »  |  PDF »

Sequence-specific DNA binding by a short peptide dimer.

R. Talanian, C. McKnight, and P. Kim (1990)
Science 249, 769-771
 |  Abstract »  |  PDF »

Design of DNA-binding peptides based on the leucine zipper motif.

K. O'Neil, R. Hoess, and W. DeGrado (1990)
Science 249, 774-778
 |  Abstract »  |  PDF »

The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor..

K K Perkins, A Admon, N Patel, and R Tjian (1990)
Genes & Dev. 4, 822-834
 |  Abstract »  |  PDF »

Different requirements for formation of Jun: Jun and Jun: Fos complexes..

T Smeal, P Angel, J Meek, and M Karin (1989)
Genes & Dev. 3, 2091-2100
 |  Abstract »  |  PDF »

Assembly of the native heterodimer of Rana esculenta tropomyosin by chain exchange.

S. Lehrer, Y. Qian, and S Hvidt (1989)
Science 246, 926-928
 |  Abstract »  |  PDF »

Recombinant Small Subunit of Smooth Muscle Myosin Light Chain Phosphatase. MOLECULAR PROPERTIES AND INTERACTIONS WITH THE TARGETING SUBUNIT.

K. Langsetmo, W. F. Stafford III, K. Mabuchi, and T. Tao (2001)
J. Biol. Chem. 276, 34318-34322
 |  Abstract »  |  Full Text »  |  PDF »

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