Science 21 April 1989: Vol. 244. no. 4902, pp. 362 - 364 DOI: 10.1126/science.2496467

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Articles

Efficient production of infectious hepatitis C virus with adaptive mutations in cultured hepatoma cells.

Y. Bungyoku, I. Shoji, T. Makine, T. Adachi, K. Hayashida, M. Nagano-Fujii, Y.-H. Ide, L. Deng, and H. Hotta (2009)
J. Gen. Virol. 90, 1681-1691
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor.

T.-I Lin, O. Lenz, G. Fanning, T. Verbinnen, F. Delouvroy, A. Scholliers, K. Vermeiren, A. Rosenquist, M. Edlund, B. Samuelsson, et al. (2009)
Antimicrob. Agents Chemother. 53, 1377-1385
 |  Abstract »  |  Full Text »  |  PDF »

Clinical Performance Evaluation of Four Automated Chemiluminescence Immunoassays for Hepatitis C Virus Antibody Detection.

S. Kim, J.-H. Kim, S. Yoon, Y.-H. Park, and H.-S. Kim (2008)
J. Clin. Microbiol. 46, 3919-3923
 |  Abstract »  |  Full Text »  |  PDF »

The History of Tumor Virology.

R. T. Javier and J. S. Butel (2008)
Cancer Res. 68, 7693-7706
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Broad CD4+ and CD8+ T-Cell Responses and Cross- Neutralizing Antibodies against Hepatitis C Virus by Vaccination with Th1-Adjuvanted Polypeptides Followed by Defective Alphaviral Particles Expressing Envelope Glycoproteins gpE1 and gpE2 and Nonstructural Proteins 3, 4, and 5 .

Y. Lin, T. Kwon, J. Polo, Y.-F. Zhu, S. Coates, K. Crawford, C. Dong, M. Wininger, J. Hall, M. Selby, et al. (2008)
J. Virol. 82, 7492-7503
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis C in Schizophrenia: Screening Experience in a Community-Dwelling Clozapine Cohort.

O. Freudenreich, R. T. Gandhi, J. P. Walsh, D. C. Henderson, and D. C. Goff (2007)
Psychosomatics 48, 405-411
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of the PA28{gamma}-Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein.

H. Miyamoto, K. Moriishi, K. Moriya, S. Murata, K. Tanaka, T. Suzuki, T. Miyamura, K. Koike, and Y. Matsuura (2007)
J. Virol. 81, 1727-1735
 |  Abstract »  |  Full Text »  |  PDF »

E6AP Ubiquitin Ligase Mediates Ubiquitylation and Degradation of Hepatitis C Virus Core Protein.

M. Shirakura, K. Murakami, T. Ichimura, R. Suzuki, T. Shimoji, K. Fukuda, K. Abe, S. Sato, M. Fukasawa, Y. Yamakawa, et al. (2007)
J. Virol. 81, 1174-1185
 |  Abstract »  |  Full Text »  |  PDF »

High-affinity aptamers to subtype 3a hepatitis C virus polymerase display genotypic specificity..

L. A. Jones, L. E. Clancy, W. D. Rawlinson, and P. A. White (2006)
Antimicrob. Agents Chemother. 50, 3019-3027
 |  Abstract »  |  Full Text »  |  PDF »

Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein..

S. Sato, M. Fukasawa, Y. Yamakawa, T. Natsume, T. Suzuki, I. Shoji, H. Aizaki, T. Miyamura, and M. Nishijima (2006)
J. Biochem. 139, 921-930
 |  Abstract »  |  Full Text »  |  PDF »

E2 of Hepatitis C Virus Inhibits Apoptosis.

S. H. Lee, Y. K. Kim, C. S. Kim, S. K. Seol, J. Kim, S. Cho, Y. L. Song, R. Bartenschlager, and S. K. Jang (2005)
J. Immunol. 175, 8226-8235
 |  Abstract »  |  Full Text »  |  PDF »

Interferon resistance of hepatitis C virus replicon-harbouring cells is caused by functional disruption of type I interferon receptors.

K. Naka, K. Takemoto, K.-i. Abe, H. Dansako, M. Ikeda, K. Shimotohno, and N. Kato (2005)
J. Gen. Virol. 86, 2787-2792
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis C Virus NS2/3 Processing Is Required for NS3 Stability and Viral RNA Replication.

S. Welbourn, R. Green, I. Gamache, S. Dandache, V. Lohmann, R. Bartenschlager, K. Meerovitch, and A. Pause (2005)
J. Biol. Chem. 280, 29604-29611
 |  Abstract »  |  Full Text »  |  PDF »

Simultaneous Detection of Hepatitis C Virus (HCV) Core Antigen and Anti-HCV Antibodies Improves the Early Detection of HCV Infection.

S. Laperche, N. Le Marrec, A. Girault, F. Bouchardeau, A. Servant-Delmas, M. Maniez-Montreuil, P. Gallian, T. Levayer, P. Morel, and N. Simon (2005)
J. Clin. Microbiol. 43, 3877-3883
 |  Abstract »  |  Full Text »  |  PDF »

Design of Novel Conformational and Genotype-Specific Antigens for Improving Sensitivity of Immunoassays for Hepatitis C Virus-Specific Antibodies.

S. Lin, P. Arcangel, A. Medina-Selby, D. Coit, P. Ng, S. Nguyen, C. McCoin, A. Gyenes, C. Hu, L. Tandeske, et al. (2005)
J. Clin. Microbiol. 43, 3917-3924
 |  Abstract »  |  Full Text »  |  PDF »

Genetic variation and dynamics of hepatitis C virus replicons in long-term cell culture.

N. Kato, T. Nakamura, H. Dansako, K. Namba, K.-i. Abe, A. Nozaki, K. Naka, M. Ikeda, and K. Shimotohno (2005)
J. Gen. Virol. 86, 645-656
 |  Abstract »  |  Full Text »  |  PDF »

Nonhepatic Cell Lines HeLa and 293 Support Efficient Replication of the Hepatitis C Virus Genotype 2a Subgenomic Replicon.

T. Kato, T. Date, M. Miyamoto, Z. Zhao, M. Mizokami, and T. Wakita (2005)
J. Virol. 79, 592-596
 |  Abstract »  |  Full Text »  |  PDF »

Genetic diversity and evolution of hepatitis C virus - 15 years on.

P. Simmonds (2004)
J. Gen. Virol. 85, 3173-3188
 |  Abstract »  |  Full Text »  |  PDF »

Intramembrane Proteolysis and Endoplasmic Reticulum Retention of Hepatitis C Virus Core Protein.

K. Okamoto, K. Moriishi, T. Miyamura, and Y. Matsuura (2004)
J. Virol. 78, 6370-6380
 |  Abstract »  |  Full Text »  |  PDF »

Steatosis and intrahepatic lymphocyte recruitment in hepatitis C virus transgenic mice.

T. Alonzi, C. Agrati, B. Costabile, C. Cicchini, L. Amicone, C. Cavallari, C. D. Rocca, A. Folgori, C. Fipaldini, F. Poccia, et al. (2004)
J. Gen. Virol. 85, 1509-1520
 |  Abstract »  |  Full Text »  |  PDF »

Genotype 2a Hepatitis C Virus Subgenomic Replicon Can Replicate in HepG2 and IMY-N9 Cells.

T. Date, T. Kato, M. Miyamoto, Z. Zhao, K. Yasui, M. Mizokami, and T. Wakita (2004)
J. Biol. Chem. 279, 22371-22376
 |  Abstract »  |  Full Text »  |  PDF »

Benefit of interferon therapy in hepatocellular carcinoma prevention for individual patients with chronic hepatitis C.

H Yoshida, R Tateishi, Y Arakawa, M Sata, S Fujiyama, S Nishiguchi, H Ishibashi, G Yamada, O Yokosuka, Y Shiratori, et al. (2004)
Gut 53, 425-430
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of Common Liver Problems.

A. L. Adrain, H. Ramberan, and G. J. Weaver (2004)
J Am Podiatr Med Assoc 94, 149-156
 |  Abstract »  |  Full Text »  |  PDF »

Promotion of Microsatellite Instability by Hepatitis C Virus Core Protein in Human Non-neoplastic Hepatocyte Cells.

A. Naganuma, H. Dansako, T. Nakamura, A. Nozaki, and N. Kato (2004)
Cancer Res. 64, 1307-1314
 |  Abstract »  |  Full Text »  |  PDF »

Laboratory Evaluation of a Fully Automated Chemiluminescence Immunoassay for Rapid Detection of HBsAg, Antibodies to HBsAg, and Antibodies to Hepatitis C Virus.

N. Ismail, G. E. Fish, and M. B. Smith (2004)
J. Clin. Microbiol. 42, 610-617
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Purification of a Hepatitis C Virus NS3/4A Complex, and Characterization of Its Helicase Activity with the Scintillation Proximity Assay System.

K. Kyono, M. Miyashiro, and I. Taguchi (2004)
J. Biochem. 135, 245-252
 |  Abstract »  |  Full Text »  |  PDF »

Evolutionary study of HVR1 of E2 in chronic hepatitis C virus infection.

V. Alfonso, D. M. Flichman, S. Sookoian, V. A. Mbayed, and R. H. Campos (2004)
J. Gen. Virol. 85, 39-46
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Proteasome Activator PA28{gamma}-Dependent Nuclear Retention and Degradation of Hepatitis C Virus Core Protein.

K. Moriishi, T. Okabayashi, K. Nakai, K. Moriya, K. Koike, S. Murata, T. Chiba, K. Tanaka, R. Suzuki, T. Suzuki, et al. (2003)
J. Virol. 77, 10237-10249
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of ATPase Activity of a Hepatitis C Virus NS3 Helicase Domain, and Analysis Involving Mercuric Reagents.

K. Kyono, M. Miyashiro, and I. Taguchi (2003)
J. Biochem. 134, 505-511
 |  Abstract »  |  Full Text »  |  PDF »

Morphine Enhances Hepatitis C Virus (HCV) Replicon Expression.

Y. Li, T. Zhang, S. D. Douglas, J.-P. Lai, W.-D. Xiao, D. E. Pleasure, and W.-Z. Ho (2003)
Am. J. Pathol. 163, 1167-1175
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis C Virus NS5A Protein Modulates c-Jun N-terminal Kinase through Interaction with Tumor Necrosis Factor Receptor-associated Factor 2.

K.-J. Park, S.-H. Choi, D.-H. Choi, J.-M. Park, S. W. Yie, S. Y. Lee, and S. B. Hwang (2003)
J. Biol. Chem. 278, 30711-30718
 |  Abstract »  |  Full Text »  |  PDF »

Managing Occupational Risks for Hepatitis C Transmission in the Health Care Setting.

D. K. Henderson (2003)
Clin. Microbiol. Rev. 16, 546-568
 |  Abstract »  |  Full Text »  |  PDF »

An NS3 Serine Protease Inhibitor Abrogates Replication of Subgenomic Hepatitis C Virus RNA.

A. Pause, G. Kukolj, M. Bailey, M. Brault, F. Do, T. Halmos, L. Lagace, R. Maurice, M. Marquis, G. McKercher, et al. (2003)
J. Biol. Chem. 278, 20374-20380
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Hepatitis C Virus RNA Replication by 2'-Modified Nucleoside Analogs.

S. S. Carroll, J. E. Tomassini, M. Bosserman, K. Getty, M. W. Stahlhut, A. B. Eldrup, B. Bhat, D. Hall, A. L. Simcoe, R. LaFemina, et al. (2003)
J. Biol. Chem. 278, 11979-11984
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Lactoferrin-derived Peptide Possessing Binding Activity to Hepatitis C Virus E2 Envelope Protein.

A. Nozaki, M. Ikeda, A. Naganuma, T. Nakamura, M. Inudoh, K. Tanaka, and N. Kato (2003)
J. Biol. Chem. 278, 10162-10173
 |  Abstract »  |  Full Text »  |  PDF »

Laboratory Assays for Diagnosis and Management of Hepatitis C Virus Infection.

S. S. Richter (2002)
J. Clin. Microbiol. 40, 4407-4412
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Quantification of Hepatitis C Virus in Human Liver and Serum Samples by Using LightCycler Reverse Transcriptase PCR.

P. A. White, Y. Pan, A. J. Freeman, G. Marinos, R. A. Ffrench, A. R. Lloyd, and W. D. Rawlinson (2002)
J. Clin. Microbiol. 40, 4346-4348
 |  Abstract »  |  Full Text »  |  PDF »

Diverging Effects of Human Recombinant Anti-Hepatitis C Virus (HCV) Antibody Fragments Derived from a Single Patient on the Infectivity of a Vesicular Stomatitis Virus/HCV Pseudotype.

R. Burioni, Y. Matsuura, N. Mancini, H. Tani, T. Miyamura, P. E. Varaldo, and M. Clementi (2002)
J. Virol. 76, 11775-11779
 |  Abstract »  |  Full Text »  |  PDF »

Highly Sensitive Multiplex Assay for Detection of Human Immunodeficiency Virus Type 1 and Hepatitis C Virus RNA.

C. Giachetti, J. M. Linnen, D. P. Kolk, J. Dockter, K. Gillotte-Taylor, M. Park, M. Ho-Sing-Loy, M. K. McCormick, L. T. Mimms, and S. H. McDonough (2002)
J. Clin. Microbiol. 40, 2408-2419
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Hepatitis C Virus Proteins Induces Distinct Membrane Alterations Including a Candidate Viral Replication Complex.

D. Egger, B. Wolk, R. Gosert, L. Bianchi, H. E. Blum, D. Moradpour, and K. Bienz (2002)
J. Virol. 76, 5974-5984
 |  Abstract »  |  Full Text »  |  PDF »

Comparison of Second- and Third-Generation Enzyme Immunoassays for Detecting Antibodies to Hepatitis C Virus.

M. Abdel-Hamid, M. El-Daly, S. El-Kafrawy, N. Mikhail, G. T. Strickland, and A. D. Fix (2002)
J. Clin. Microbiol. 40, 1656-1659
 |  Abstract »  |  Full Text »  |  PDF »

Nonstructural 5A Protein of Hepatitis C Virus Modulates Tumor Necrosis Factor alpha -stimulated Nuclear Factor kappa B Activation.

K.-J. Park, S.-H. Choi, S. Y. Lee, S. B. Hwang, and M. M. C. Lai (2002)
J. Biol. Chem. 277, 13122-13128
 |  Abstract »  |  Full Text »  |  PDF »

Use of Polymerase Chain Reaction for Early Detection and Management of Hepatitis C Virus Infection after Needlestick Injury.

T. Y. Wang, H. T. Kuo, L. C. Chen, Y. T. Chen, C. N. Lin, and M. M. Lee (2002)
Ann. Clin. Lab. Sci. 32, 137-141
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis C Virus (HCV) NS5A Binds RNA-dependent RNA Polymerase (RdRP) NS5B and Modulates RNA-dependent RNA Polymerase Activity.

Y. Shirota, H. Luo, W. Qin, S. Kaneko, T. Yamashita, K. Kobayashi, and S. Murakami (2002)
J. Biol. Chem. 277, 11149-11155
 |  Abstract »  |  Full Text »  |  PDF »

Persistent and Transient Replication of Full-Length Hepatitis C Virus Genomes in Cell Culture.

T. Pietschmann, V. Lohmann, A. Kaul, N. Krieger, G. Rinck, G. Rutter, D. Strand, and R. Bartenschlager (2002)
J. Virol. 76, 4008-4021
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of the C-Terminal Membrane Anchor Domains of Hepatitis C Virus Glycoproteins E1 and E2: toward a Topological Model.

B. Charloteaux, L. Lins, H. Moereels, and R. Brasseur (2002)
J. Virol. 76, 1944-1958
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In Vitro Characterization of a Purified NS2/3 Protease Variant of Hepatitis C Virus.

D. Thibeault, R. Maurice, L. Pilote, D. Lamarre, and A. Pause (2001)
J. Biol. Chem. 276, 46678-46684
 |  Abstract »  |  Full Text »  |  PDF »

Mapping B-Cell Epitopes of Hepatitis C Virus E2 Glycoprotein Using Human Monoclonal Antibodies from Phage Display Libraries.

F. Bugli, N. Mancini, C.-Y. Kang, C. Di Campli, A. Grieco, A. Manzin, A. Gabrielli, A. Gasbarrini, G. Fadda, P. E. Varaldo, et al. (2001)
J. Virol. 75, 9986-9990
 |  Abstract »  |  Full Text »  |  PDF »

The dynamics of hepatitis C virus binding to platelets and 2 mononuclear cell lines.

S. Hamaia, C. Li, and J.-P. Allain (2001)
Blood 98, 2293-2300
 |  Abstract »  |  Full Text »  |  PDF »

Novel Approach To Reduce the Hepatitis C Virus (HCV) Window Period: Clinical Evaluation of a New Enzyme-Linked Immunosorbent Assay for HCV Core Antigen.

G. Icardi, F. Ansaldi, B. M. Bruzzone, P. Durando, S. Lee, C. de Luigi, and P. Crovari (2001)
J. Clin. Microbiol. 39, 3110-3114
 |  Abstract »  |  Full Text »  |  PDF »

Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase.

C.-L. Tai, W.-C. Pan, S.-H. Liaw, U.-C. Yang, L.-H. Hwang, and D.-S. Chen (2001)
J. Virol. 75, 8289-8297
 |  Abstract »  |  Full Text »  |  PDF »

Design, high-level expression, purification and characterization of soluble fragments of the hepatitis C virus NS3 RNA helicase suitable for NMR-based drug discovery methods and mechanistic studies.

J. J. Gesell, D. Liu, V. S. Madison, T. Hesson, Y.-S. Wang, P. C. Weber, and D. F. Wyss (2001)
Protein Eng. Des. Sel. 14, 573-582
 |  Abstract »  |  Full Text »  |  PDF »

Clinical guidelines on the management of hepatitis C.

J C L Booth, J O'Grady, and J Neuberger (2001)
Gut 49, I1-21
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Detection of Diverse Hepatitis C Virus (HCV)-Specific Cytotoxic T Lymphocytes in Peripheral Blood of Infected Persons by Screening for Responses to All Translated Proteins of HCV.

D. K. H. Wong, D. D. Dudley, P. B. Dohrenwend, G. M. Lauer, R. T. Chung, D. L. Thomas, and B. D. Walker (2001)
J. Virol. 75, 1229-1235
 |  Abstract »  |  Full Text »

In Situ Detection of Hepatitis C Virus RNA in Salivary Glands.

J. J. Arrieta, E. Rodriguez-Inigo, N. Ortiz-Movilla, J. Bartolome, M. Pardo, F. Manzarbeitia, H. Oliva, D. M. Macias, and V. Carreno (2001)
Am. J. Pathol. 158, 259-264
 |  Abstract »  |  Full Text »  |  PDF »

Depression in Korean Immigrants With Hepatitis B and Related Liver Diseases.

E. J.S. Kunkel, J. S. Kim, H.-W. Hann, O. Oyesanmi, L. A. Menefee, H. L. Field, P. L. Lartey, and R. E. Myers (2000)
Psychosomatics 41, 472-480
 |  Abstract »  |  Full Text »

Roles of the AX4GKS and Arginine-Rich Motifs of Hepatitis C Virus RNA Helicase in ATP- and Viral RNA-Binding Activity.

S. C. Chang, J.-C. Cheng, Y.-H. Kou, C.-H. Kao, C.-H. Chiu, H.-Y. Wu, and M.-F. Chang (2000)
J. Virol. 74, 9732-9737
 |  Abstract »  |  Full Text »

Prognosis of Anti-Hepatitis C Virus Antibody-Positive Patients on Regular Hemodialysis Therapy.

E. NAKAYAMA, T. AKIBA, F. MARUMO, and C. SATO (2000)
J. Am. Soc. Nephrol. 11, 1896-1902
 |  Abstract »  |  Full Text »

Recommendations for the Outpatient Surveillance of Renal Transplant Recipients.

B. L. KASISKE, M. A. VAZQUEZ, W. E. HARMON, R. S. BROWN, G. M. DANOVITCH, R. S. GASTON, D. ROTH, J. D. SCANDLING JR., and G. G. SINGER (2000)
J. Am. Soc. Nephrol. 11 , S1-S86
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Interferon-Inducible 2'-5'-Oligoadenylate Synthetase Gene by Hepatitis C Virus Core Protein.

A. Naganuma, A. Nozaki, T. Tanaka, K. Sugiyama, H. Takagi, M. Mori, K. Shimotohno, and N. Kato (2000)
J. Virol. 74, 8744-8750
 |  Abstract »  |  Full Text »

Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core protein.

R. G. Hope and J. McLauchlan (2000)
J. Gen. Virol. 81, 1913-1925
 |  Abstract »  |  Full Text »

Prevalence of hepatitis C among pregnant women attending an inner London obstetric department: uptake and acceptability of named antenatal testing.

C Ward, G Tudor-Williams, T Cotzias, S Hargreaves, L Regan, and G R Foster (2000)
Gut 47, 277-280
 |  Abstract »  |  Full Text »  |  PDF »

Transfusion Medicine: An Overview and Update.

P. M. Ness (2000)
Clin. Chem. 46, 1270-1276
 |  Abstract »  |  Full Text »  |  PDF »

Development of a High Throughput Scintillation Proximity Assay for Hepatitis C Virus NS3 Protease That Reduces the Proportion of Competitive Inhibitors Identified.

A. Fowler, M. Price-Jones, K. Hughes, J. Anson, R. Lingham, and M. Schulman (2000)
J Biomol Screen 5, 153-158
 |  Abstract »  |  PDF »

Cell Fusion Activity of Hepatitis C Virus Envelope Proteins.

S. Takikawa, K. Ishii, H. Aizaki, T. Suzuki, H. Asakura, Y. Matsuura, and T. Miyamura (2000)
J. Virol. 74, 5066-5074
 |  Abstract »  |  Full Text »

Nonstructural Protein 5A of Hepatitis C Virus Inhibits the Function of Karyopherin beta 3.

K. M. Chung, J. Lee, J.-E. Kim, O.-K. Song, S. Cho, J. Lim, M. Seedorf, B. Hahm, and S. K. Jang (2000)
J. Virol. 74, 5233-5241
 |  Abstract »  |  Full Text »

EFFECT OF ALCOHOL CONSUMPTION ON THE PROGRESSION OF HEPATITIS C VIRUS INFECTION AND RISK OF HEPATOCELLULAR CARCINOMA IN JAPANESE PATIENTS.

K. N. KHAN and H. YATSUHASHI (2000)
Alcohol Alcohol. 35, 286-295
 |  Abstract »  |  Full Text »  |  PDF »

Clinical Significance of Hepatitis C Virus Genotypes.

N. N. Zein (2000)
Clin. Microbiol. Rev. 13, 223-235
 |  Abstract »  |  Full Text »  |  PDF »

Enhancement of Immunoglobulin G2a and Cytotoxic T-Lymphocyte Responses by a Booster Immunization with Recombinant Hepatitis C Virus E2 Protein in E2 DNA-Primed Mice.

M. K. Song, S. W. Lee, Y. S. Suh, K. J. Lee, and Y. C. Sung (2000)
J. Virol. 74, 2920-2925
 |  Abstract »  |  Full Text »

Biochemical characterization of a hepatitis C virus RNA-dependent RNA polymerase mutant lacking the C-terminal hydrophobic sequence.

L. Tomei, R. L. Vitale, I. Incitti, S. Serafini, S. Altamura, A. Vitelli, and R. De Francesco (2000)
J. Gen. Virol. 81, 759-767
 |  Abstract »  |  Full Text »

Subcellular Localization, Stability, and trans-Cleavage Competence of the Hepatitis C Virus NS3-NS4A Complex Expressed in Tetracycline-Regulated Cell Lines.

B. Wölk, D. Sansonno, H.-G. Kräusslich, F. Dammacco, C. M. Rice, H. E. Blum, and D. Moradpour (2000)
J. Virol. 74, 2293-2304
 |  Abstract »  |  Full Text »

De Novo Initiation of RNA Synthesis by Hepatitis C Virus Nonstructural Protein 5B Polymerase.

W. Zhong, A. S. Uss, E. Ferrari, J. Y. N. Lau, and Z. Hong (2000)
J. Virol. 74, 2017-2022
 |  Abstract »  |  Full Text »

Simplified Hepatitis C Virus Genotyping by Heteroduplex Mobility Analysis.

P. A. White, X. Zhai, I. Carter, Y. Zhao, and W. D. Rawlinson (2000)
J. Clin. Microbiol. 38, 477-482
 |  Abstract »  |  Full Text »

Clinical and Histologic Features of Chronic Hepatitis C Virus Infection After Blood Transfusion in Japanese Children.

A. Hoshiyama, A. Kimura, T. Fujisawa, M. Kage, and H. Kato (2000)
Pediatrics 105, 62-65
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Hepatitis C Virus NS2/3 Processing by NS4A Peptides. IMPLICATIONS FOR CONTROL OF VIRAL PROCESSING.

P. L. Darke, A. R. Jacobs, L. Waxman, and L. C. Kuo (1999)
J. Biol. Chem. 274, 34511-34514
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of Hepatitis C Virus Core Protein with Viral Sense RNA and Suppression of Its Translation.

T. Shimoike, S. Mimori, H. Tani, Y. Matsuura, and T. Miyamura (1999)
J. Virol. 73, 9718-9725
 |  Abstract »  |  Full Text »

Expression of Hepatitis C Virus Proteins Inhibits Signal Transduction through the Jak-STAT Pathway.

M. H. Heim, D. Moradpour, and H. E. Blum (1999)
J. Virol. 73, 8469-8475
 |  Abstract »  |  Full Text »  |  PDF »

Structure-Based Mutagenesis Study of Hepatitis C Virus NS3 Helicase.

C. Lin and J. L. Kim (1999)
J. Virol. 73, 8798-8807
 |  Abstract »  |  Full Text »  |  PDF »

Fulminant hepatic failure in acute hepatitis C: increased risk in chronic carriers of hepatitis B virus.

C M Chu, C T Yeh, and Y F Liaw (1999)
Gut 45, 613-617
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Noncovalent Hepatitis C Virus Envelope E1-E2 Complexes Is Not Required for the Induction of Antibodies with Neutralizing Properties following DNA Immunization.

A. Fournillier, E. Depla, P. Karayiannis, O. Vidalin, G. Maertens, C. Trépo, and G. Inchauspé (1999)
J. Virol. 73, 7497-7504
 |  Abstract »  |  Full Text »

Lack of evidence for the heterosexual transmission of hepatitis C.

G. Neumayr, A. Propst, H. Schwaighofer, G. Judmaier, and W. Vogel (1999)
QJM 92, 505-508
 |  Abstract »  |  Full Text »  |  PDF »

The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994.

M. J. Alter, D. Kruszon-Moran, O. V. Nainan, G. M. McQuillan, F. Gao, L. A. Moyer, R. A. Kaslow, and H. S. Margolis (1999)
N. Engl. J. Med. 341, 556-562
 |  Abstract »  |  Full Text »  |  PDF »

Anti-HCV seropositivity among haemodialysis patients of Iranian origin.

G. Rais-Jalali and P. Khajehdehi (1999)
Nephrol. Dial. Transplant. 14, 2055-2056
 |  Full Text »  |  PDF »

High prevalence of anti-hepatitis B virus serological markers in patients with hepatitis C virus related chronic liver disease in Japan.

H Marusawa, Y Osaki, T Kimura, K Ito, Y Yamashita, T Eguchi, M Kudo, Y Yamamoto, H Kojima, H Seno, et al. (1999)
Gut 45, 284-288
 |  Abstract »  |  Full Text »  |  PDF »

Development of a Simple and Highly Sensitive Enzyme Immunoassay for Hepatitis C Virus Core Antigen.

K. Aoyagi, C. Ohue, K. Iida, T. Kimura, E. Tanaka, K. Kiyosawa, and S. Yagi (1999)
J. Clin. Microbiol. 37, 1802-1808
 |  Abstract »  |  Full Text »

Hepatitis C Virus Core Protein Inhibits Fas- and Tumor Necrosis Factor Alpha-Mediated Apoptosis via NF-kappa B Activation.

H. Marusawa, M. Hijikata, T. Chiba, and K. Shimotohno (1999)
J. Virol. 73, 4713-4720
 |  Abstract »  |  Full Text »

Hepatitis C Virus Core Protein Binds to a DEAD Box RNA Helicase.

N. Mamiya and H. J. Worman (1999)
J. Biol. Chem. 274, 15751-15756
 |  Abstract »  |  Full Text »  |  PDF »

Use of a Novel Hepatitis C Virus (HCV) Major-Epitope Chimeric Polypeptide for Diagnosis of HCV Infection.

D. Y. Chien, P. Arcangel, A. Medina-Selby, D. Coit, M. Baumeister, S. Nguyen, C. George-Nascimento, A. Gyenes, G. Kuo, and P. Valenzuela (1999)
J. Clin. Microbiol. 37, 1393-1397
 |  Abstract »  |  Full Text »

Hepatitis C Virus Core Protein Interacts with Cellular Putative RNA Helicase.

L.-R. You, C.-M. Chen, T.-S. Yeh, T.-Y. Tsai, R.-T. Mai, C.-H. Lin, and Y.-H. W. Lee (1999)
J. Virol. 73, 2841-2853
 |  Abstract »  |  Full Text »

Hepatitis C virus recurrence after liver transplantation.

T BIZOLLON, C DUCERF, C TREPO, and D MUTIMER (1999)
Gut 44, 575-578
 |  Abstract »  |  Full Text »  |  PDF »

High-Throughput Real-Time Reverse Transcription-PCR Quantitation of Hepatitis C Virus RNA.

M. Martell, J. Gómez, J. I. Esteban, S. Sauleda, J. Quer, B. Cabot, R. Esteban, and J. Guardia (1999)
J. Clin. Microbiol. 37, 327-332
 |  Abstract »  |  Full Text »

Poliovirus/Hepatitis C Virus (Internal Ribosomal Entry Site-Core) Chimeric Viruses: Improved Growth Properties through Modification of a Proteolytic Cleavage Site and Requirement for Core RNA Sequences but Not for Core-Related Polypeptides.

W. D. Zhao, E. Wimmer, and F. C. Lahser (1999)
J. Virol. 73, 1546-1554
 |  Abstract »  |  Full Text »

Hepatitis C Virus Core Protein Enhances NF-kappa B Signal Pathway Triggering by Lymphotoxin-beta Receptor Ligand and Tumor Necrosis Factor Alpha.

L.-R. You, C.-M. Chen, and Y.-H. W. Lee (1999)
J. Virol. 73, 1672-1681
 |  Abstract »  |  Full Text »

Genetic and Serological Evidence for Multiple Instances of Unrecognized Transmission of Hepatitis C Virus in Hemodialysis Units.

M. Mizuno, T. Higuchi, K. Kanmatsuse, and M. Esumi (1998)
J. Clin. Microbiol. 36, 2926-2931
 |  Abstract »  |  Full Text »

Confirmation of Nosocomial Transmission of Hepatitis C Virus by Phylogenetic Analysis of the NS5-B Region.

H. Norder, A. Bergström, I. Uhnoo, J. Aldén, L. Weiss, J. Czajkowski, and L. Magnius (1998)
J. Clin. Microbiol. 36, 3066-3069
 |  Abstract »  |  Full Text »

Optimal Induction of Hepatitis C Virus Envelope-Specific Immunity by Bicistronic Plasmid DNA Inoculation with the Granulocyte-Macrophage Colony-Stimulating Factor Gene.

S. W. Lee, J. H. Cho, and Y. C. Sung (1998)
J. Virol. 72, 8430-8436
 |  Abstract »  |  Full Text »  |  PDF »

The Metal Binding Site of the Hepatitis C Virus NS3 Protease. A SPECTROSCOPIC INVESTIGATION.

A. Urbani, R. Bazzo, M. C. Nardi, D. O. Cicero, R. De Francesco, C. Steinkuhler, and G. Barbato (1998)
J. Biol. Chem. 273, 18760-18769
 |  Abstract »  |  Full Text »  |  PDF »

The Native Form and Maturation Process of Hepatitis C Virus Core Protein.

K. Yasui, T. Wakita, K. Tsukiyama-Kohara, S.-I. Funahashi, M. Ichikawa, T. Kajita, D. Moradpour, J. R. Wands, and M. Kohara (1998)
J. Virol. 72, 6048-6055
 |  Abstract »  |  Full Text »  |  PDF »

RNA-dependent RNA Polymerase Activity of the Soluble Recombinant Hepatitis C Virus NS5B Protein Truncated at the C-terminal Region.

T. Yamashita, S. Kaneko, Y. Shirota, W. Qin, T. Nomura, K. Kobayashi, and S. Murakami (1998)
J. Biol. Chem. 273, 15479-15486
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis C Virus Infections in Dialysis Centers in The Netherlands: a National Survey by Serological and Molecular Methods.

P. M. Schneeberger, I. Keur, W. van der Vliet, K. van Hoek, H. Boswijk, A. M. van Loon, W. C. van Dijk, R. H. Kauffmann, W. Quint, and L.-J. van Doorn (1998)
J. Clin. Microbiol. 36, 1711-1715
 |  Abstract »  |  Full Text »

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