Science 27 January 1989: Vol. 243. no. 4890, pp. 500 - 507 DOI: 10.1126/science.2643164

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Articles

Thematic Review Series: Sphingolipids. New insights into sphingolipid metabolism and function in budding yeast.

R. C. Dickson (2008)
J. Lipid Res. 49, 909-921
 |  Abstract »  |  Full Text »  |  PDF »

Sphingosine-1-Phosphate Via Activation of a G-Protein-Coupled Receptor(s) Enhances the Excitability of Rat Sensory Neurons.

Y. H. Zhang, J. C. Fehrenbacher, M. R. Vasko, and G. D. Nicol (2006)
J Neurophysiol 96, 1042-1052
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons.

Y. H. Zhang, M. R. Vasko, and G. D. Nicol (2006)
J. Physiol. 575, 101-113
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Convenient Structural Analysis of Glycosphingolipids Using MALDI-QIT-TOF Mass Spectrometry with Increased Laser Power and Cooling Gas Flow..

Y. Suzuki, M. Suzuki, E. Ito, N. Goto-Inoue, K. Miseki, J. Iida, Y. Yamazaki, M. Yamada, and A. Suzuki (2006)
J. Biochem. 139, 771-777
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The BAR Domain Proteins: Molding Membranes in Fission, Fusion, and Phagy.

G. Ren, P. Vajjhala, J. S. Lee, B. Winsor, and A. L. Munn (2006)
Microbiol. Mol. Biol. Rev. 70, 37-120
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Activation of the Sphingosine Kinase-Signaling Pathway by High Glucose Mediates the Proinflammatory Phenotype of Endothelial Cells.

L. Wang, X.-P. Xing, A. Holmes, C. Wadham, J. R. Gamble, M. A. Vadas, and P. Xia (2005)
Circ. Res. 97, 891-899
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Sphingosine 1-phosphate protects mouse extensor digitorum longus skeletal muscle during fatigue.

D. Danieli-Betto, E. Germinario, A. Esposito, A. Megighian, M. Midrio, B. Ravara, E. Damiani, L. D. Libera, R. A. Sabbadini, and R. Betto (2005)
Am J Physiol Cell Physiol 288, C1367-C1373
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Disturbance of Sphingolipid Biosynthesis Abrogates the Signaling of Mss4, Phosphatidylinositol-4-phosphate 5-Kinase, in Yeast.

T. Kobayashi, H. Takematsu, T. Yamaji, S. Hiramoto, and Y. Kozutsumi (2005)
J. Biol. Chem. 280, 18087-18094
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Characterizing the Sphingolipid Signaling Pathway That Remediates Defects Associated with Loss of the Yeast Amphiphysin-like Orthologs, Rvs161p and Rvs167p.

M. Germann, E. Swain, L. Bergman, and J. T. Nickels Jr. (2005)
J. Biol. Chem. 280, 4270-4278
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Sphingosine-dependent apoptosis: A unified concept based on multiple mechanisms operating in concert.

E. Suzuki, K. Handa, M. S. Toledo, and S. Hakomori (2004)
PNAS 101, 14788-14793
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Intrinsic Cytotoxicity and Chemomodulatory Actions of Novel Phenethylisothiocyanate Sphingoid Base Derivatives in HL-60 Human Promyelocytic Leukemia Cells.

C. R. Johnson, J. Chun, R. Bittman, and W. D. Jarvis (2004)
J. Pharmacol. Exp. Ther. 309, 452-461
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Expression Cloning of a Human cDNA Restoring Sphingomyelin Synthesis and Cell Growth in Sphingomyelin Synthase-defective Lymphoid Cells.

S. Yamaoka, M. Miyaji, T. Kitano, H. Umehara, and T. Okazaki (2004)
J. Biol. Chem. 279, 18688-18693
 |  Abstract »  |  Full Text »  |  PDF »

The structural requirements for ceramide activation of serine-threonine protein phosphatases.

C. E. Chalfant, Z. Szulc, P. Roddy, A. Bielawska, and Y. A. Hannun (2004)
J. Lipid Res. 45, 496-506
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Sphingosine-dependent Protein Kinase-1, Directed to 14-3-3, Is Identified as the Kinase Domain of Protein Kinase C{delta}.

A. Hamaguchi, E. Suzuki, K. Murayama, T. Fujimura, T. Hikita, K. Iwabuchi, K. Handa, D. A. Withers, S. C. Masters, H. Fu, et al. (2003)
J. Biol. Chem. 278, 41557-41565
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Enhanced Serine Palmitoyltransferase Expression in Proliferating Fibroblasts, Transformed Cell Lines, and Human Tumors.

J. M. Carton, D. J. Uhlinger, A. D. Batheja, C. Derian, G. Ho, D. Argenteri, and M. R. D'Andrea (2003)
J. Histochem. Cytochem. 51, 715-726
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Characterization of Serine Palmitoyltransferase in Normal Human Tissues.

A. D. Batheja, D. J. Uhlinger, J. M. Carton, G. Ho, and M. R. D'Andrea (2003)
J. Histochem. Cytochem. 51, 687-696
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Effect of Glycosphingolipids Purified from Leishmania (Leishmania) amazonensis Amastigotes on Human Peripheral Lymphocytes.

S. Giorgio, M. R. M. Santos, A. H. Straus, H. K. Takahashi, and C. L. Barbieri (2003)
Clin. Vaccine Immunol. 10, 469-472
 |  Abstract »  |  Full Text »  |  PDF »

Alveolar sphingolipids generated in response to TNF-alpha modifies surfactant biophysical activity.

A. J. Ryan, D. M. McCoy, S. E. McGowan, R. G. Salome, and R. K. Mallampalli (2003)
J Appl Physiol 94, 253-258
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Yeast Cells Lacking the ARV1 Gene Harbor Defects in Sphingolipid Metabolism. COMPLEMENTATION BY HUMAN ARV1.

E. Swain, J. Stukey, V. McDonough, M. Germann, Y. Liu, S. L. Sturley, and J. T. Nickels Jr. (2002)
J. Biol. Chem. 277, 36152-36160
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Sterol-dependent Regulation of Sphingolipid Metabolism in Saccharomyces cerevisiae.

E. Swain, K. Baudry, J. Stukey, V. McDonough, M. Germann, and J. T. Nickels Jr. (2002)
J. Biol. Chem. 277, 26177-26184
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Myocardial Dysfunction With Coronary Microembolization: Signal Transduction Through a Sequence of Nitric Oxide, Tumor Necrosis Factor-{alpha}, and Sphingosine.

M. Thielmann, H. Dorge, C. Martin, S. Belosjorow, U. Schwanke, A. van de Sand, I. Konietzka, A. Buchert, A. Kruger, R. Schulz, et al. (2002)
Circ. Res. 90, 807-813
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Characterization of Murine Sphingosine-1-phosphate Phosphohydrolase.

H. Le Stunff, C. Peterson, R. Thornton, S. Milstien, S. M. Mandala, and S. Spiegel (2002)
J. Biol. Chem. 277, 8920-8927
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Coupled assay of sphingomyelin and ceramide molecular species by gas liquid chromatography.

C. Vieu, F. Terce, F. Chevy, C. Rolland, R. Barbaras, H. Chap, C. Wolf, B. Perret, and X. Collet (2002)
J. Lipid Res. 43, 510-522
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Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide.

C. Berry, R. Touyz, A. F. Dominiczak, R. C. Webb, and D. G. Johns (2001)
Am J Physiol Heart Circ Physiol 281, H2337-H2365
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Interleukin 1 Upregulates Ovarian Prostaglandin Endoperoxide Synthase-2 Expression: Evidence for Prostaglandin-Dependent/Ceramide-Independent Transcriptional Stimulation and for Message Stabilization.

J. Saito, M. Ando, D. Sussman, H. Negishi, G. King, and E. Y. Adashi (2001)
Biol Reprod 65, 1759-1765
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Protein Kinase Calpha Plays a Critical Role in Mannosylerythritol Lipid-induced Differentiation of Melanoma B16 Cells.

X. Zhao, T. Murata, S. Ohno, N. Day, J. Song, N. Nomura, T. Nakahara, and K. K. Yokoyama (2001)
J. Biol. Chem. 276, 39903-39910
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Neutrophil recruitment, chemokine receptors, and resistance to mucosal infection.

G. Godaly, G. Bergsten, L. Hang, H. Fischer, B. Frendeus, A.-C. Lundstedt, M. Samuelsson, P. Samuelsson, and C. Svanborg (2001)
J. Leukoc. Biol. 69, 899-906
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Chromatographic resolution and quantitative assay of CNS tissue sphingoids and sphingolipids.

S. Dasgupta and E. L. Hogan (2001)
J. Lipid Res. 42, 301-308
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Kinetic steps for the hydrolysis of sphingomyelin by Bacillus cereus sphingomyelinase in lipid monolayers.

M. L. Fanani and B. Maggio (2000)
J. Lipid Res. 41, 1832-1840
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ACTIVATION OF NEUTRAL SPHINGOMYELINASE PARTICIPATES IN ETHANOL-INDUCED APOPTOSIS IN HEP G2 CELLS.

J.-J. Liu, J.-Y. Wang, E. Hertervig, Y. Cheng, A. Nilsson, and R.-D. Duan (2000)
Alcohol Alcohol. 35, 569-573
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Periovulatory and Interleukin (IL)-1--Dependent Reglation of IL-6 in the Immature Rat Ovary: A Specific IL-1 Receptor-Mediated Eicosanoid-Dependent Effect.

K. W. Chung, M. Ando, and E. Y. Adashi (2000)
Reproductive Sciences 7, 301-308
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Purified Fumonisin B1 Decreases Cardiovascular Function but Does Not Alter Pulmonary Capillary Permeability in Swine.

G. W. Smith, P. D. Constable, R. M. Eppley, M. E. Tumbleson, L. A. Gumprecht, and W. M. Haschek-Hock (2000)
Toxicol. Sci. 56, 240-249
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Sli2 (Ypk1), a Homologue of Mammalian Protein Kinase SGK, Is a Downstream Kinase in the Sphingolipid-Mediated Signaling Pathway of Yeast.

Y. Sun, R. Taniguchi, D. Tanoue, T. Yamaji, H. Takematsu, K. Mori, T. Fujita, T. Kawasaki, and Y. Kozutsumi (2000)
Mol. Cell. Biol. 20, 4411-4419
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Novel plasmalogalactosylalkylglycerol from equine brain.

Y. Yachida, M. Kashiwagi, T. Mikami, K. Tsuchihashi, T. Daino, T. Akino, and S. Gasa (1999)
J. Lipid Res. 40, 2271-2278
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Ceramide Inhibits L-Type Calcium Channel Currents in Rat Pinealocytes.

C. L. Chik, B. Li, T. Negishi, E. Karpinski, and A. K. Ho (1999)
Endocrinology 140, 5682-5690
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Phase behavior and molecular interactions in mixtures of ceramide with dipalmitoylphosphatidylcholine.

D. C. Carrer and B. Maggio (1999)
J. Lipid Res. 40, 1978-1989
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Mass Spectrometric Identification of Increased C16 Ceramide Levels During Apoptosis.

R. L. Thomas Jr., C. M. Matsko, M. T. Lotze, and A. A. Amoscato (1999)
J. Biol. Chem. 274, 30580-30588
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Antifungal Activities of Antineoplastic Agents: Saccharomyces cerevisiae as a Model System To Study Drug Action.

M. E. Cardenas, M. C. Cruz, M. Del Poeta, N. Chung, J. R. Perfect, and J. Heitman (1999)
Clin. Microbiol. Rev. 12, 583-611
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Cell cycle control of PDGF-induced Ca2+ signaling through modulation of sphingolipid metabolism.

A. FATATIS and R. J. MILLER (1999)
FASEB J 13, 1291-1301
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Differential Pharmacological Properties and Signal Transduction of the Sphingosine 1-Phosphate Receptors EDG-1, EDG-3, and EDG-5.

N. Ancellin and T. Hla (1999)
J. Biol. Chem. 274, 18997-19002
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New methods for determining the enantiomeric purity of erythro -sphingosine.

S. Li, W. K. Wilson, and G. J. Schroepfer , Jr. (1999)
J. Lipid Res. 40, 764-772
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TNF-alpha increases ceramide without inducing apoptosis in alveolar type II epithelial cells.

R. K. Mallampalli, E. J. Peterson, A. B. Carter, R. G. Salome, S. N. Mathur, and G. A. Koretzky (1999)
Am J Physiol Lung Cell Mol Physiol 276, L481-L490
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Protein kinase C potentiates transmitter release from the chick ciliary presynaptic terminal by increasing the exocytotic fusion probability.

H. Yawo (1999)
J. Physiol. 515, 169-180
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Expression of Glucosylceramide Synthase, Converting Ceramide to Glucosylceramide, Confers Adriamycin Resistance in Human Breast Cancer Cells.

Y.-Y. Liu, T.-Y. Han, A. E. Giuliano, and M. C. Cabot (1999)
J. Biol. Chem. 274, 1140-1146
 |  Abstract »  |  Full Text »  |  PDF »

Mannosylerythritol Lipid Is a Potent Inducer of Apoptosis and Differentiation of Mouse Melanoma Cells in Culture.

X. Zhao, Y. Wakamatsu, M. Shibahara, N. Nomura, C. Geltinger, T. Nakahara, T. Murata, and K. K. Yokoyama (1999)
Cancer Res. 59, 482-486
 |  Abstract »  |  Full Text »  |  PDF »

Daunorubicin- and Mitoxantrone-Triggered Phosphatidylcholine Hydrolysis: Implication in Drug-Induced Ceramide Generation and Apoptosis.

A. Bettaïeb, I. Plo, V. Mansat-De Mas, A. Quillet-Mary, T. Levade, G. Laurent, and J.-P. Jaffrézou (1999)
Mol. Pharmacol. 55, 118-125
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A Novel Mechanism of CD4 Down-modulation Induced by Monosialoganglioside GM3. INVOLVEMENT OF SERINE PHOSPHORYLATION AND PROTEIN KINASE C delta  TRANSLOCATION.

T. Garofalo, M. Sorice, R. Misasi, B. Cinque, M. Giammatteo, G. M. Pontieri, M. G. Cifone, and A. Pavan (1998)
J. Biol. Chem. 273, 35153-35160
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Cerebrosides A and C, Sphingolipid Elicitors of Hypersensitive Cell Death and Phytoalexin Accumulation in Rice Plants.

J. Koga, T. Yamauchi, M. Shimura, N. Ogawa, K. Oshima, K. Umemura, M. Kikuchi, and N. Ogasawara (1998)
J. Biol. Chem. 273, 31985-31991
 |  Abstract »  |  Full Text »  |  PDF »

Development of Fumonisin-Induced Hepatotoxicity and Pulmonary Edema in Orally Dosed Swine: Morphological and Biochemical Alterations.

L. A. Gumprecht, V. R. Beasley, R. M. Weigel, H. M. Parker, M. E. Tumbleson, C. W. Bacon, F. I. Meredith, and W. M. Haschek (1998)
Toxicol Pathol 26, 777-788
 |  Abstract »  |  PDF »

Cytokine-mediated Induction of Ceramide Production Is Redox-sensitive. IMPLICATIONS TO PROINFLAMMATORY CYTOKINE-MEDIATED APOPTOSIS IN DEMYELINATING DISEASES.

I. Singh, K. Pahan, M. Khan, and A. K. Singh (1998)
J. Biol. Chem. 273, 20354-20362
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Beneficial effects of N,N,N-trimethylsphingosine following ischemia and reperfusion in the isolated perfused rat heart.

B. Campbell, Y. K. Shin, R. Scalia, and A. M. Lefer (1998)
Cardiovasc Res 39, 393-400
 |  Abstract »  |  Full Text »  |  PDF »

The Cellular Trafficking and Zinc Dependence of Secretory and Lysosomal Sphingomyelinase, Two Products of the Acid Sphingomyelinase Gene.

S. L. Schissel, G. A. Keesler, E. H. Schuchman, K. J. Williams, and I. Tabas (1998)
J. Biol. Chem. 273, 18250-18259
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Stereochemical structures of synthesized and natural plasmalogalactosylceramides from equine brain.

Y. Yachida, M. Kashiwagi, T. Mikami, K. Tsuchihashi, T. Daino, T. Akino, and S. Gasa (1998)
J. Lipid Res. 39, 1039-1045
 |  Abstract »  |  Full Text »  |  PDF »

Syringomycin Action Gene SYR2 Is Essential for Sphingolipid 4-Hydroxylation in Saccharomyces cerevisiae.

M. M. Grilley, S. D. Stock, R. C. Dickson, R. L. Lester, and J. Y. Takemoto (1998)
J. Biol. Chem. 273, 11062-11068
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Sphingosine Inhibits Voltage-operated Calcium Channels in GH4C1 Cells.

A. Titievsky, I. Titievskaya, M. Pasternack, K. Kaila, and K. Tornquist (1998)
J. Biol. Chem. 273, 242-247
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Role of sphingolipid-mediated cell death in neurodegenerative diseases.

T. Ariga, W. D. Jarvis, and R. K. Yu (1998)
J. Lipid Res. 39, 1-16
 |  Abstract »  |  Full Text »

Coordinate Regulation of Stress- and Mitogen-Activated Protein Kinases in the Apoptotic Actions of Ceramide and Sphingosine.

W. D. Jarvis, F. A. Fornari Jr., K. L. Auer, A. J. Freemerman, E. Szabo, M. J. Birrer, C. R. Johnson, S. E. Barbour, P. Dent, and S. Grant (1997)
Mol. Pharmacol. 52, 935-947
 |  Abstract »  |  Full Text »

Identification and Characterization of Saccharomyces cerevisiae Dihydrosphingosine-1-phosphate Phosphatase.

C. Mao, M. Wadleigh, G. M. Jenkins, Y. A. Hannun, and L. M. Obeid (1997)
J. Biol. Chem. 272, 28690-28694
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Sphingosine 1-Phosphate Mobilizes Sequestered Calcium, Activates Calcium Entry, and Stimulates Deoxyribonucleic Acid Synthesis in Thyroid FRTL-5 Cells.

K. Tornquist, P. Saarinen, M. Vainio, and M. Ahlstrom (1997)
Endocrinology 138, 4049-4057
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Roles for Ceramide and Glucosylceramide at Different Stages of Neuronal Growth.

A. Schwarz and A. H. Futerman (1997)
J. Neurosci. 17, 2929-2938
 |  Abstract »  |  Full Text »  |  PDF »

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species. ROLE OF MITOCHONDRIAL GLUTATHIONE.

C. Garcia-Ruiz, A. Colell, M. Mari, A. Morales, and J. C. Fernandez-Checa (1997)
J. Biol. Chem. 272, 11369-11377
 |  Abstract »  |  Full Text »  |  PDF »

1alpha ,25-Dihydroxyvitamin D3 Induces Sphingomyelin Hydrolysis in HaCaT Cells via Tumor Necrosis Factor alpha.

C. C. Geilen, M. Bektas, T. Wieder, V. Kodelja, S. Goerdt, and C. E. Orfanos (1997)
J. Biol. Chem. 272, 8997-9001
 |  Abstract »  |  Full Text »  |  PDF »

Changing J774A.1 Cells to New Medium Perturbs Multiple Signaling Pathways, Including the Modulation of Protein Kinase C by Endogenous Sphingoid Bases.

E. R. Smith, P. L. Jones, J. M. Boss, and A. H. Merrill Jr. (1997)
J. Biol. Chem. 272, 5640-5646
 |  Abstract »  |  Full Text »  |  PDF »

Platelet-derived Growth Factor (PDGF)-induced Ca2+ Signaling in the CG4 Oligodendroglial Cell Line and in Transformed Oligodendrocytes Expressing the beta -PDGF Receptor.

A. Fatatis and R. J. Miller (1997)
J. Biol. Chem. 272, 4351-4358
 |  Abstract »  |  Full Text »  |  PDF »

Elevation of Ceramide within Distal Neurites Inhibits Neurite Growth in Cultured Rat Sympathetic Neurons.

E. I.P. de Chaves, M. Bussiere, D. E. Vance, R. B. Campenot, and J. E. Vance (1997)
J. Biol. Chem. 272, 3028-3035
 |  Abstract »  |  Full Text »  |  PDF »

Agents that Reverse Multidrug Resistance, Tamoxifen, Verapamil, and Cyclosporin A, Block Glycosphingolipid Metabolism by Inhibiting Ceramide Glycosylation in Human Cancer Cells.

Y. Lavie, H.-t. Cao, A. Volner, A. Lucci, T.-Y. Han, V. Geffen, A. E. Giuliano, and M. C. Cabot (1997)
J. Biol. Chem. 272, 1682-1687
 |  Abstract »  |  Full Text »  |  PDF »

Phenotype of arylsulfatase A-deficient mice: Relationship to human metachromatic leukodystrophy.

B. Hess, P. Saftig, D. Hartmann, R. Coenen, R. Lullmann-Rauch, H. H. Goebel, M. Evers, K. von Figura, R. D'Hooge, G. Nagels, et al. (1996)
PNAS 93, 14821-14826
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning and Expression of a Fifth Type of alpha 2,8-Sialyltransferase (ST8Sia V). ITS SUBSTRATE SPECIFICITY IS SIMILAR TO THAT OF SAT-V/III, WHICH SYNTHESIZE GD1c, GT1a, GQ1b AND GT3.

M. Kono, Y. Yoshida, N. Kojima, and S. Tsuji (1996)
J. Biol. Chem. 271, 29366-29371
 |  Abstract »  |  Full Text »  |  PDF »

c-Jun Is a Downstream Target for Ceramide-activated Protein Phosphatase in A431 Cells.

J. G. Reyes, I. G. Robayna, P. S. Delgado, I. H. Gonzalez, J. Q. Aguiar, F. E. Rosas, L. F. Fanjul, and C. M.R. d. Galarreta (1996)
J. Biol. Chem. 271, 21375-21380
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of Glucosylceramides in Multidrug-resistant Cancer Cells.

Y. Lavie, H.-t. Cao, S. L. Bursten, A. E. Giuliano, and M. C. Cabot (1996)
J. Biol. Chem. 271, 19530-19536
 |  Abstract »  |  Full Text »  |  PDF »

Zn2+-stimulated Sphingomyelinase Is Secreted by Many Cell Types and Is a Product of the Acid Sphingomyelinase Gene.

S. L. Schissel, E. H. Schuchman, K. J. Williams, and I. Tabas (1996)
J. Biol. Chem. 271, 18431-18436
 |  Abstract »  |  Full Text »  |  PDF »

Complete Removal of Sphingolipids from the Plasma Membrane Disrupts Cell to Substratum Adhesion of Mouse Melanoma Cells.

K. I.-P. J. Hidari, S. Ichikawa, T. Fujita, H. Sakiyama, and Y. Hirabayashi (1996)
J. Biol. Chem. 271, 14636-14641
 |  Abstract »  |  Full Text »  |  PDF »

The Distal Pathway of Lipoprotein-induced Cholesterol Esterification, but Not Sphingomyelinase-induced Cholesterol Esterification, Is Energy-dependent.

P. J. Skiba, X. Zha, F. R. Maxfield, S. L. Schissel, and I. Tabas (1996)
J. Biol. Chem. 271, 13392-13400
 |  Abstract »  |  Full Text »  |  PDF »

Ca[IMAGE] Mobilizing Action of Sphingosine in Jurkat Human Leukemia T Cells.

S. Sakano, H. Takemura, K. Yamada, K. Imoto, M. Kaneko, and H. Ohshika (1996)
J. Biol. Chem. 271, 11148-11155
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Regulatory Role of Ceramide in Interleukin (IL)-1beta-induced E-selectin Expression in Human Umbilical Vein Endothelial Cells.

A. Masamune, Y. Igarashi, and S.-i. Hakomori (1996)
J. Biol. Chem. 271, 9368-9375
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Apoptosis and Potentiation of Ceramide-mediated Cytotoxicity by Sphingoid Bases in Human Myeloid Leukemia Cells.

W. D. Jarvis, F. A. Fornari Jr., R. S. Traylor, H. A. Martin, L. B. Kramer, R. K. Erukulla, R. Bittman, and S. Grant (1996)
J. Biol. Chem. 271, 8275-8284
 |  Abstract »  |  Full Text »  |  PDF »

Purification and Characterization of UDP-glucose:Ceramide Glucosyltransferase from Rat Liver Golgi Membranes.

P. Paul, Y. Kamisaka, D. L. Marks, and R. E. Pagano (1996)
J. Biol. Chem. 271, 2287-2293
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Plasmalopsychosine of Human Brain Mimics the Effect of Nerve Growth Factor by Activating Its Receptor Kinase and Mitogen-activated Protein Kinase in PC12 Cells.

C. Sakakura, Y. Igarashi, J. K. Anand, K. K. Sadozai, and S.-i. Hakomori (1996)
J. Biol. Chem. 271, 946-952
 |  Abstract »  |  Full Text »  |  PDF »

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T.-c. Lee, M.-c. Ou, K. Shinozaki, B. Malone, and F. Snyder (1996)
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J. R. Guyton and K. F. Klemp (1996)
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F. Okajima and Y. Kondo (1995)
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C. N. Inoue, H. G. Forster, and M. Epstein (1995)
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Ceramide As a Modulator of Endocytosis.

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J. C. Strum, K. I. Swenson, J. E. Turner, and R. M. Bell (1995)
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Involvement of a Pertussis Toxin-sensitive G Protein in the Mitogenic Signaling Pathways of Sphingosine 1-Phosphate.

K. A. Goodemote, M. E. Mattie, A. Berger, and S. Spiegel (1995)
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Sphingolipid-gated Ca[IMAGE] Release from Intracellular Stores of Endothelial Cells Is Mediated by a Novel Ca[IMAGE]-permeable Channel.

S. Kim, V. Lakhani, D. J. Costa, A. I. Sharara, J. G. Fitz, L.-W. Huang, K. G. Peters, and L. A. Kindman (1995)
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Cell Cycle Arrest Induced by an Inhibitor of Glucosylceramide Synthase.

C. S. S. Rani, A. Abe, Y. Chang, N. Rosenzweig, A. R. Saltiel, N. S. Radin, and J. A. Shayman (1995)
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Severe Failure to Thrive and Liver Dysfunction as the Main Manifestations of a New Variant of Niemann-Pick Disease.

S. Reif, Z. Spirer, G. Messer, M. Baratz, B. Bembi, and Y. Bujanover (1994)
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Programmed cell death induced by ceramide.

L. Obeid, C. Linardic, L. Karolak, and Y. Hannun (1993)
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Cell cycle-dependent coupling of the calcitonin receptor to different G proteins.

M Chakraborty, D Chatterjee, S Kellokumpu, H Rasmussen, and R Baron (1991)
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Generation of calcium oscillations in fibroblasts by positive feedback between calcium and IP3.

A. Harootunian, J. Kao, S Paranjape, and R. Tsien (1991)
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Cell Adhesion Proteins in Oral Biology.

S. B. Milam, C. Haskin, G. Zardeneta, Dali Chen, V. L. Magnuson, R. J. Klebe, and B. Steffenson (1991)
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An unusual form of lipid linkage to the CD45 peptide.

A Takeda and A. Maizel (1990)
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Intracellular calcium release mediated by sphingosine derivatives generated in cells.

T. Ghosh, J Bian, and D. Gill (1990)
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Sphingolipids Signal Heat Stress-induced Ubiquitin-dependent Proteolysis.

N. Chung, G. Jenkins, Y. A. Hannun, J. Heitman, and L. M. Obeid (2000)
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A Novel Plasmal Conjugate to Glycerol and Psychosine ("Glyceroplasmalopsychosine"). ISOLATION AND CHARACTERIZATION FROM BOVINE BRAIN WHITE MATTER.

T. Hikita, K. Tadano-Aritomi, N. Iida-Tanaka, J. K. Anand, I. Ishizuka, and S.-i. Hakomori (2001)
J. Biol. Chem. 276, 23084-23091
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Myocardial Dysfunction With Coronary Microembolization: Signal Transduction Through a Sequence of Nitric Oxide, Tumor Necrosis Factor-{alpha}, and Sphingosine.

M. Thielmann, H. Dorge, C. Martin, S. Belosjorow, U. Schwanke, A. van de Sand, I. Konietzka, A. Buchert, A. Kruger, R. Schulz, et al. (2002)
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