Science 8 July 1988: Vol. 241. no. 4862, pp. 218 - 221 DOI: 10.1126/science.3388033

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Articles

RbAp48 Is a Critical Mediator Controlling the Transforming Activity of Human Papillomavirus Type 16 in Cervical Cancer.

L. Kong, X.-P. Yu, X.-H. Bai, W.-F. Zhang, Y. Zhang, W.-M. Zhao, J.-H. Jia, W. Tang, Y.-B. Zhou, and C.-j. Liu (2007)
J. Biol. Chem. 282, 26381-26391
 |  Abstract »  |  Full Text »  |  PDF »

Selective Requirements for E2f3 in the Development and Tumorigenicity of Rb-Deficient Chimeric Tissues.

T. Parisi, T. L. Yuan, A. M. Faust, A. M. Caron, R. Bronson, and J. A. Lees (2007)
Mol. Cell. Biol. 27, 2283-2293
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TReP-132 Is a Novel Progesterone Receptor Coactivator Required for the Inhibition of Breast Cancer Cell Growth and Enhancement of Differentiation by Progesterone..

F. Gizard, R. Robillard, B. Gross, O. Barbier, F. Revillion, J.-P. Peyrat, G. Torpier, D. W. Hum, and B. Staels (2006)
Mol. Cell. Biol. 26, 7632-7644
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Eye Cancer: Unique Insights into Oncogenesis The Cogan Lecture.

J. W. Harbour (2006)
Invest. Ophthalmol. Vis. Sci. 47, 1737-1745
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Primary and Compensatory Roles for RB Family Members at Cell Cycle Gene Promoters That Are Deacetylated and Downregulated in Doxorubicin-Induced Senescence of Breast Cancer Cells..

J. G. Jackson and O. M. Pereira-Smith (2006)
Mol. Cell. Biol. 26, 2501-2510
 |  Abstract »  |  Full Text »  |  PDF »

The Retinoblastoma Protein Is Required for Ras-Induced Oncogenic Transformation.

J. P. Williams, T. Stewart, B. Li, R. Mulloy, D. Dimova, and M. Classon (2006)
Mol. Cell. Biol. 26, 1170-1182
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Liver-Specific pRB Loss Results in Ectopic Cell Cycle Entry and Aberrant Ploidy.

C. N. Mayhew, E. E. Bosco, S. R. Fox, T. Okaya, P. Tarapore, S. J. Schwemberger, G. F. Babcock, A. B. Lentsch, K. Fukasawa, and E. S. Knudsen (2005)
Cancer Res. 65, 4568-4577
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Down-Regulation of LATS1 and LATS2 mRNA Expression by Promoter Hypermethylation and Its Association with Biologically Aggressive Phenotype in Human Breast Cancers.

Y. Takahashi, Y. Miyoshi, C. Takahata, N. Irahara, T. Taguchi, Y. Tamaki, and S. Noguchi (2005)
Clin. Cancer Res. 11, 1380-1385
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Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130.

J.-H. Dannenberg, L. Schuijff, M. Dekker, M. van der Valk, and H. t. Riele (2004)
Genes & Dev. 18, 2952-2962
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic opportunities for cell cycle re-entry and cardiac regeneration.

K. M. Regula, M. J. Rzeszutek, D. Baetz, C. Seneviratne, and L. A. Kirshenbaum (2004)
Cardiovasc Res 64, 395-401
 |  Abstract »  |  Full Text »  |  PDF »

Ras Protects Rb Family Null Fibroblasts from Cell Death: A ROLE FOR AP-1.

A. P. Young and G. D. Longmore (2004)
J. Biol. Chem. 279, 10931-10938
 |  Abstract »  |  Full Text »  |  PDF »

Genes Involved in Breast Cancer Progression: Analysis of Global Changes in Gene Expression or Retroviral Tagging?.

E. V. Schmidt (2002)
Am. J. Pathol. 161, 1973-1977
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Loss of cyclin D1 and p16 expression correlates with local recurrence in nasopharyngeal carcinoma following radiotherapy.

C.-F. Hwang, C.-L. Cho, C.-C. Huang, J.-S. Wang, Y.-L. Shih, C.-Y. Su, and H.-W. Chang (2002)
Ann. Onc. 13, 1246-1251
 |  Abstract »  |  Full Text »  |  PDF »

Noninvasive Imaging of Spontaneous Retinoblastoma Pathway-dependent Tumors in Mice.

M. Vooijs, J. Jonkers, S. Lyons, and A. Berns (2002)
Cancer Res. 62, 1862-1867
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Basis of Low-Penetrance Retinoblastoma.

J. W. Harbour (2001)
Arch Ophthalmol 119, 1699-1704
 |  Abstract »  |  Full Text »  |  PDF »

Alterations of p14ARF, p53, and p73 Genes Involved in the E2F-1-mediated Apoptotic Pathways in Non-Small Cell Lung Carcinoma.

S. A. Nicholson, N. T. Okby, M. A. Khan, J. A. Welsh, M. G. McMenamin, W. D. Travis, J. R. Jett, H. D. Tazelaar, V. Trastek, P. C. Pairolero, et al. (2001)
Cancer Res. 61, 5636-5643
 |  Abstract »  |  Full Text »  |  PDF »

p53 and p21waf-1 Expression Correlates with Apoptosis or Cell Survival in Poorly Differentiated, but not Well-Differentiated, Retinoblastomas.

A. Divan, J. Lawry, I. R. Dunsmore, M. A. Parsons, and J. A. Royds (2001)
Cancer Res. 61, 3157-3163
 |  Abstract »  |  Full Text »

Protection of Normal Proliferating Cells Against Chemotherapy by Staurosporine-Mediated, Selective, and Reversible G1 Arrest.

X. Chen, M. Lowe, T. Herliczek, M. J. Hall, C. Danes, D. A. Lawrence, and K. Keyomarsi (2000)
J Natl Cancer Inst 92, 1999-2008
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Ablation of the Retinoblastoma gene family deregulates G1 control causing immortalization and increased cell turnover under growth-restricting conditions.

J.-H. Dannenberg, A. van Rossum, L. Schuijff, and H. te Riele (2000)
Genes & Dev. 14, 3051-3064
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The Rb/E2F pathway: expanding roles and emerging paradigms.

J. W. Harbour and D. C. Dean (2000)
Genes & Dev. 14, 2393-2409
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Transactivation of the Human cdc2 Promoter by Adenovirus E1A. E1A INDUCES THE EXPRESSION AND ASSEMBLY OF A HETEROMERIC COMPLEX CONSISTING OF THE CCAAT BOX BINDING FACTOR, CBF/NF-Y, AND A 110-kDa DNA-BINDING PROTEIN.

C.-Y. Kao, A. Tanimoto, N. Arima, Y. Sasaguri, and R. Padmanabhan (1999)
J. Biol. Chem. 274, 23043-23051
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Lymph Node Metastasis Is Associated with Allelic Loss on Chromosome 13q12-13 in Esophageal Squamous Cell Carcinoma1.

H. Harada, H. Tanaka, Y. Shimada, M. Shinoda, M. Imamura, and K. Ishizaki (1999)
Cancer Res. 59, 3724-3729
 |  Abstract »  |  Full Text »  |  PDF »

Elevated Frequency of Loss of Heterozygosity in Mammary Tumors Arising in Mouse Mammary Tumor Virus/neu Transgenic Mice.

M. Cool and P. Jolicoeur (1999)
Cancer Res. 59, 2438-2444
 |  Abstract »  |  Full Text »  |  PDF »

G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: Phenotypes reversed by a tumorigenic mutation.

J. L. Dai, R. K. Bansal, and S. E. Kern (1999)
PNAS 96, 1427-1432
 |  Abstract »  |  Full Text »  |  PDF »

Raf-1 Physically Interacts with Rb and Regulates Its Function: a Link between Mitogenic Signaling and Cell Cycle Regulation.

S. Wang, R. N. Ghosh, and S. P. Chellappan (1998)
Mol. Cell. Biol. 18, 7487-7498
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Differential Regulation of Androgen and Glucocorticoid Receptors by Retinoblastoma Protein.

J. Lu and M. Danielsen (1998)
J. Biol. Chem. 273, 31528-31533
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Rapid sequencing of the p53 gene with a new automated DNA sequencer.

B. S. Bharaj, K. Angelopoulou, and E. P. Diamandis (1998)
Clin. Chem. 44, 1397-1403
 |  Abstract »  |  Full Text »  |  PDF »

p107 is a suppressor of retinoblastoma development in pRb-deficient mice.

E. Robanus-Maandag, M. Dekker, M. van der Valk, M.-L. Carrozza, J.-C. Jeanny, J.-H. Dannenberg, A. Berns, and H. te Riele (1998)
Genes & Dev. 12, 1599-1609
 |  Abstract »  |  Full Text »

Novel Mechanisms of E2F Induction by BK Virus Large-T Antigen: Requirement of Both the pRb-Binding and the J Domains.

K. F. Harris, J. B. Christensen, E. H. Radany, and M. J. Imperiale (1998)
Mol. Cell. Biol. 18, 1746-1756
 |  Abstract »  |  Full Text »

Pituitary Tumor Pathogenesis.

I. Shimon and S. Melmed (1997)
J. Clin. Endocrinol. Metab. 82, 1675-1681
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Altered Expression of the Retinoblastoma Tumor-Suppressor Gene in Leukemic Cell Lines Inhibits Induction of Differentiation But Not G1-Accumulation.

G. Bergh, M. Ehinger, T. Olofsson, B. Baldetorp, E. Johnsson, H. Brycke, G. Lindgren, I. Olsson, and U. Gullberg (1997)
Blood 89, 2938-2950
 |  Abstract »  |  Full Text »  |  PDF »

The p120-v-Abl Protein Interacts with E2F-1 and Regulates E2F-1 Transcriptional Activity.

M. C. Birchenall-Roberts, Y. D. Yoo, D. C. Bertolette III, K.-H. Lee, J. M. Turley, O.-S. Bang, F. W. Ruscetti, and S.-J. Kim (1997)
J. Biol. Chem. 272, 8905-8911
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin E, a redundant cyclin in breast cancer.

J. Gray-Bablin, J. Zalvide, M. P. Fox, C. J. Knickerbocker, J. A. DeCaprio, and K. Keyomarsi (1996)
PNAS 93, 15215-15220
 |  Abstract »  |  Full Text »  |  PDF »

The Retinoblastoma Gene Product (Rb) Induces Binding of a Conformationally Inactive Nuclear Factor-kappa B.

M. Tamami, P. F. Lindholm, and J. N. Brady (1996)
J. Biol. Chem. 271, 24551-24556
 |  Abstract »  |  Full Text »  |  PDF »

Targeted disruption of p107: functional overlap between p107 and Rb..

M H Lee, B O Williams, G Mulligan, S Mukai, R T Bronson, N Dyson, E Harlow, and T Jacks (1996)
Genes & Dev. 10, 1621-1632
 |  Abstract »  |  PDF »

Effects of Tumor Necrosis Factor-alpha on Antimitogenicity and Cell Cycle-related Proteins in MCF-7 Cells.

D.-i. Jeoung, B. Tang, and M. Sonenberg (1995)
J. Biol. Chem. 270, 18367-18373
 |  Abstract »  |  Full Text »  |  PDF »

Detection of a Novel Cell Cycle-regulated Kinase Activity That Associates with the Amino Terminus of the Retinoblastoma Protein in G[IMAGE]/M Phases.

J. M. Sterner, Y. Murata, H. G. Kim, S. B. Kennett, D. J. Templeton, and J. M. Horowitz (1995)
J. Biol. Chem. 270, 9281-9288
 |  Abstract »  |  Full Text »  |  PDF »

Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product.

M. Chang, E Barr, J Seltzer, Y. Jiang, G. Nabel, E. Nabel, M. Parmacek, and J. Leiden (1995)
Science 267, 518-522
 |  Abstract »  |  PDF »

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

R Wooster, S. Neuhausen, J Mangion, Y Quirk, D Ford, N Collins, K Nguyen, S Seal, T Tran, D Averill, et al. (1994)
Science 265, 2088-2090
 |  Abstract »  |  PDF »

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53..

K A Howes, N Ransom, D S Papermaster, J G Lasudry, D M Albert, and J J Windle (1994)
Genes & Dev. 8, 1300-1310
 |  Abstract »  |  PDF »

Identification of a growth suppression domain within the retinoblastoma gene product..

X Q Qin, T Chittenden, D M Livingston, and W G Kaelin (1992)
Genes & Dev. 6, 953-964
 |  Abstract »  |  PDF »

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F..

S W Hiebert, S P Chellappan, J M Horowitz, and J R Nevins (1992)
Genes & Dev. 6, 177-185
 |  Abstract »  |  PDF »

Tumor suppressor genes.

R. Weinberg (1991)
Science 254, 1138-1146
 |  Abstract »  |  PDF »

Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

R Bookstein, J. Shew, P. Chen, P Scully, and W. Lee (1990)
Science 247, 712-715
 |  Abstract »  |  PDF »

Tumor suppressor genes: the puzzle and the promise.

R Sager (1989)
Science 246, 1406-1412
 |  Abstract »  |  PDF »

p53: a frequent target for genetic abnormalities in lung cancer.

T Takahashi, M. Nau, I Chiba, M. Birrer, R. Rosenberg, M Vinocour, M Levitt, H Pass, A. Gazdar, and J. Minna (1989)
Science 246, 491-494
 |  Abstract »  |  PDF »

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product.

N Dyson, P. Howley, K Munger, and E Harlow (1989)
Science 243, 934-937
 |  Abstract »  |  PDF »

Point mutational inactivation of the retinoblastoma antioncogene.

J. Horowitz, D. Yandell, S. Park, S Canning, P Whyte, K Buchkovich, E Harlow, R. Weinberg, and T. Dryja (1989)
Science 243, 937-940
 |  Abstract »  |  PDF »

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.

H. Huang, J. Yee, J. Shew, P. Chen, R Bookstein, T Friedmann, E. Lee, and W. Lee (1988)
Science 242, 1563-1566
 |  Abstract »  |  PDF »

Identification of germline and somatic mutations affecting the retinoblastoma gene.

J. Dunn, R. Phillips, A. Becker, and B. Gallie (1988)
Science 241, 1797-1800
 |  Abstract »  |  PDF »

ANTI-ONCOGENES AND CANCER: STARTLING NEW INSIGHTS.

(1988)
Journal Watch (General) 1988, 6
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