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Science 8 July 1988:
Vol. 241. no. 4862, pp. 210 - 213
DOI: 10.1126/science.3388032
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Articles

Science, Vol 241, Issue 4862, 210-213
Copyright © 1988 by American Association for the Advancement of Science

articles

Behavioral dissociation of dishabituation, sensitization, and inhibition in Aplysia

EA Marcus, TG Nolen, CH Rankin, and TJ Carew

Department of Biology, Yale University, New Haven, CT 06520.

Three forms of nonassociative learning (habituation, dishabituation, and sensitization) have commonly been explained by a dual-process view in which a single decrementing process produces habituation and a single facilitatory process produces both dishabituation and sensitization. A key prediction of this view is that dishabituation and sensitization should always occur together. However, we show that dishabituation and sensitization, as well as an additional process, inhibition, can be behaviorally dissociated in Aplysia by (i) their differential time of onset, (ii) their differential sensitivity to stimulus intensity, and (iii) their differential emergence during development. A simple dual-process view cannot explain these results; rather, a multiprocess view appears necessary to account for nonassociative learning in Aplysia.


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Prepulse Inhibition of the Tritonia Escape Swim.
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A Simplified Preparation for Relating Cellular Events to Behavior: Mechanisms Contributing to Habituation, Dishabituation, and Sensitization of the Aplysia Gill-Withdrawal Reflex.
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Role of interneurons in defensive withdrawal reflexes in Aplysia..
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