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Science 1 July 1988: Vol. 241. no. 4861, pp. 58 - 62 DOI: 10.1126/science.2898810
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Articles
Science, Vol 241, Issue 4861, 58-62
Copyright © 1988 by American Association for the Advancement of Science
Purification and characterization of mouse hematopoietic stem cells
GJ Spangrude,
S Heimfeld,
and
IL Weissman
Department of Pathology, Stanford University School of Medicine, CA 94305.
Mouse bone marrow hematopoietic stem cells were isolated with the use of a variety of phenotypic markers. These cells can proliferate and differentiate with approximately unit efficiency into myelomonocytic cells, B cells, or T cells. Thirty of these cells are sufficient to save 50 percent of lethally irradiated mice, and to reconstitute all blood cell types in the survivors.
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Am. J. Respir. Cell Mol. Biol.
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| Abstract »
| Full Text »
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178, 6482-6494
| Abstract »
| Full Text »
| PDF »
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178, 3511-3520
| Abstract »
| Full Text »
| PDF »
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- T. Udagawa, A. E. Birsner, M. Wood, and R. J. D'Amato (2007)
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| Abstract »
| Full Text »
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| Abstract »
| Full Text »
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| Abstract »
| Full Text »
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| Abstract »
| Full Text »
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| PDF »
- Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size.
- S. Stier, Y. Ko, R. Forkert, C. Lutz, T. Neuhaus, E. Grunewald, T. Cheng, D. Dombkowski, L. M. Calvi, S. R. Rittling, et al. (2005)
J. Exp. Med.
201, 1781-1791
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- Prevention of Type 1 Diabetes with Major Histocompatibility Complex-Compatible and Nonmarrow Ablative Hematopoietic Stem Cell Transplants.
- G. F. Beilhack, R. R. Landa, M. A. Masek, and J. A. Shizuru (2005)
Diabetes
54, 1770-1779
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- Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion.
- C. C. Zhang and H. F. Lodish (2005)
Blood
105, 4314-4320
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- Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue.
- P. E. Burger, X. Xiong, S. Coetzee, S. N. Salm, D. Moscatelli, K. Goto, and E. L. Wilson (2005)
PNAS
102, 7180-7185
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- Hematopoietic cells maintain hematopoietic fates upon entering the brain.
- M. Massengale, A. J. Wagers, H. Vogel, and I. L. Weissman (2005)
J. Exp. Med.
201, 1579-1589
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