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Science 10 June 1988:
Vol. 240. no. 4858, pp. 1475 - 1482
DOI: 10.1126/science.3287624
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Articles

Science, Vol 240, Issue 4858, 1475-1482
Copyright © 1988 by American Association for the Advancement of Science

articles

Primates

FA King, CJ Yarbrough, DC Anderson, TP Gordon, and KG Gould

Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia 30322.

Nonhuman primates demonstrate marked similarities to humans in almost all aspects of their anatomy, endocrinology, and physiology. These similarities underlie the value of these animals for appropriate studies in neurobiology, immunology, pathology, reproductive biology, teratology, neonatology, endocrinology, cardiology, and psychology. Investigations with nonhuman primates has made, and continues to make, significant contributions to biomedical and behavioral research. This review provides an overview of basic and applied studies for which primates are appropriate subjects and a summary of the advantages and problems of using nonhuman primates in research.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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H. OZWARA, J. A. M. LANGERMANS, J. MAAMUN, I. O. FARAH, D. S. YOLE, J. M. MWENDA, H. WEILER, and A. W. THOMAS (2003)
Am J Trop Med Hyg 69, 188-194
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Plasmodium knowlesi Provides a Rapid In Vitro and In Vivo Transfection System That Enables Double-Crossover Gene Knockout Studies.
C. H. M. Kocken, H. Ozwara, A. van der Wel, A. L. Beetsma, J. M. Mwenda, and A. W. Thomas (2002)
Infect. Immun. 70, 655-660
   Abstract »    Full Text »    PDF »
Gene Transfer into Nonhuman Primate Hematopoietic Stem Cells: Implications for Gene Therapy.
Y. Hanazono, K. Terao, and K. Ozawa (2001)
Stem Cells 19, 12-23
   Abstract »    Full Text »
Melatonin Does Not Shift Circadian Phase in Baboons.
H. Hao and S. Rivkees (2000)
J. Clin. Endocrinol. Metab. 85, 3618-3622
   Abstract »    Full Text »
Antiretroviral-Drug Concentrations in Semen: Implications for Sexual Transmission of Human Immunodeficiency Virus Type 1.
A. D. M. Kashuba, J. R. Dyer, L. M. Kramer, R. H. Raasch, J. J. Eron, and M. S. Cohen (1999)
Antimicrob. Agents Chemother. 43, 1817-1826
   Full Text »
Animals in Research.
Council on Scientific Affairs (1989)
JAMA 261, 3602-3606
   Abstract »    PDF »
Nonhuman Primates in Neurotoxicity Screening and Neurobehavioral Toxicity Studies.
R. T. O'Keeffe and K. Lifshitz (1989)
International Journal of Toxicology 8, 127-140
   Abstract »    PDF »


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