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Science 10 June 1988:
Vol. 240. no. 4858, pp. 1443 - 1448
DOI: 10.1126/science.3287620
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Articles

Science, Vol 240, Issue 4858, 1443-1448
Copyright © 1988 by American Association for the Advancement of Science

articles

Xenopus laevis in developmental and molecular biology

IB Dawid and TD Sargent

Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, MD 20892.

Xenopus laevis is a prime system for the study of embryogenesis in vertebrates. Both prelocalized information in the egg and inductive interactions between cells contribute to the ordered increase in complexity during development. Embryonic induction, discovered in amphibians, is being studied intensely in Xenopus; recent work suggests a role for growth factors in this process. Contributions of the Xenopus system to the analysis of ribosomal and 5S RNA genes, and the diverse and highly productive applications of the oocyte injection technology, are also summarized.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Perturbation of rRNA Synthesis in the bap28 Mutation Leads to Apoptosis Mediated by p53 in the Zebrafish Central Nervous System.
M. Azuma, R. Toyama, E. Laver, and I. B. Dawid (2006)
J. Biol. Chem. 281, 13309-13316
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Science. ISSN 0036-8075 (print), 1095-9203 (online)