Science 22 April 1988: Vol. 240. no. 4851, pp. 516 - 518 DOI: 10.1126/science.3128869

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Articles

Artemisone and Artemiside Control Acute and Reactivated Toxoplasmosis in a Murine Model.

I. R. Dunay, W. C. Chan, R. K. Haynes, and L. D. Sibley (2009)
Antimicrob. Agents Chemother. 53, 4450-4456
 |  Abstract »  |  Full Text »  |  PDF »

Toxoplasma gondii Cyclophilin 18-Mediated Production of Nitric Oxide Induces Bradyzoite Conversion in a CCR5-Dependent Manner.

H. M. Ibrahim, H. Bannai, X. Xuan, and Y. Nishikawa (2009)
Infect. Immun. 77, 3686-3695
 |  Abstract »  |  Full Text »  |  PDF »

A Transmembrane Domain-Containing Surface Protein from Toxoplasma gondii Augments Replication in Activated Immune Cells and Establishment of a Chronic Infection.

A. M. Pollard, S. Skariah, D. G. Mordue, and L. J. Knoll (2009)
Infect. Immun. 77, 3731-3739
 |  Abstract »  |  Full Text »  |  PDF »

Novel role of the nitrite transporter NirC in Salmonella pathogenesis: SPI2-dependent suppression of inducible nitric oxide synthase in activated macrophages.

P. Das, A. Lahiri, A. Lahiri, and D. Chakravortty (2009)
Microbiology 155, 2476-2489
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro Effect of TNF-{alpha} and IFN-{gamma} in Retinal Cell Infection with Toxoplasma gondii.

E. Delair, C. Creuzet, J. Dupouy-Camet, and M.-P. Roisin (2009)
Invest. Ophthalmol. Vis. Sci. 50, 1754-1760
 |  Abstract »  |  Full Text »  |  PDF »

Cell-Mediated Immunity to Toxoplasma gondii Develops Primarily by Local Th1 Host Immune Responses in the Absence of Parasite Replication.

J. P. Gigley, B. A. Fox, and D. J. Bzik (2009)
J. Immunol. 182, 1069-1078
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Recognition of Toxoplasma gondii by TLR11 Prevents Parasite-Induced Immunopathology.

F. Yarovinsky, S. Hieny, and A. Sher (2008)
J. Immunol. 181, 8478-8484
 |  Abstract »  |  Full Text »  |  PDF »

Salmonella virulence factor SpiC is involved in expression of flagellin protein and mediates activation of the signal transduction pathways in macrophages.

K.-i. Uchiya and T. Nikai (2008)
Microbiology 154, 3491-3502
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Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii.

M. Flores, R. Saavedra, R. Bautista, R. Viedma, E. P. Tenorio, L. Leng, Y. Sanchez, I. Juarez, A. A. Satoskar, A. S. Shenoy, et al. (2008)
FASEB J 22, 3661-3671
 |  Abstract »  |  Full Text »  |  PDF »

TLR Adaptor MyD88 Is Essential for Pathogen Control during Oral Toxoplasma gondii Infection but Not Adaptive Immunity Induced by a Vaccine Strain of the Parasite.

W. Sukhumavasi, C. E. Egan, A. L. Warren, G. A. Taylor, B. A. Fox, D. J. Bzik, and E. Y. Denkers (2008)
J. Immunol. 181, 3464-3473
 |  Abstract »  |  Full Text »  |  PDF »

CD4 T cells: fates, functions, and faults.

J. Zhu and W. E. Paul (2008)
Blood 112, 1557-1569
 |  Abstract »  |  Full Text »  |  PDF »

IL-12 Signaling Drives CD8+ T Cell IFN-{gamma} Production and Differentiation of KLRG1+ Effector Subpopulations during Toxoplasma gondii Infection.

D. C. Wilson, S. Matthews, and G. S. Yap (2008)
J. Immunol. 180, 5935-5945
 |  Abstract »  |  Full Text »  |  PDF »

T cell expression of MyD88 is required for resistance to Toxoplasma gondii.

D. F. LaRosa, J. S. Stumhofer, A. E. Gelman, A. H. Rahman, D. K. Taylor, C. A. Hunter, and L. A. Turka (2008)
PNAS 105, 3855-3860
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: T-bet and IL-27R Are Critical for In Vivo IFN-{gamma} Production by CD8 T Cells during Infection.

K. D. Mayer, K. Mohrs, W. Reiley, S. Wittmer, J. E. Kohlmeier, J. E. Pearl, A. M. Cooper, L. L. Johnson, D. L. Woodland, and M. Mohrs (2008)
J. Immunol. 180, 693-697
 |  Abstract »  |  Full Text »  |  PDF »

Macrophage Migration Inhibitory Factor Is Up-Regulated in Human First-Trimester Placenta Stimulated by Soluble Antigen of Toxoplasma gondii, Resulting in Increased Monocyte Adhesion on Villous Explants.

E. A. V. Ferro, J. R. Mineo, F. Ietta, N. Bechi, R. Romagnoli, D. A. O. Silva, G. Sorda, E. Bevilacqua, and L. R. Paulesu (2008)
Am. J. Pathol. 172, 50-58
 |  Abstract »  |  Full Text »  |  PDF »

Death Receptor Ligation or Exposure to Perforin Trigger Rapid Egress of the Intracellular Parasite Toxoplasma gondii.

E. K. Persson, A. M. Agnarson, H. Lambert, N. Hitziger, H. Yagita, B. J. Chambers, A. Barragan, and A. Grandien (2007)
J. Immunol. 179, 8357-8365
 |  Abstract »  |  Full Text »  |  PDF »

TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-{gamma} production.

R. S. Goldszmid, A. Bafica, D. Jankovic, C. G. Feng, P. Caspar, R. Winkler-Pickett, G. Trinchieri, and A. Sher (2007)
J. Exp. Med. 204, 2591-2602
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Toxoplasma gondii Infection on the Brain.

V. B. Carruthers and Y. Suzuki (2007)
Schizophr Bull 33, 745-751
 |  Abstract »  |  Full Text »  |  PDF »

Toxoplasma gondii Dysregulates IFN-{gamma}-Inducible Gene Expression in Human Fibroblasts: Insights from a Genome-Wide Transcriptional Profiling.

S.-K. Kim, A. E. Fouts, and J. C. Boothroyd (2007)
J. Immunol. 178, 5154-5165
 |  Abstract »  |  Full Text »  |  PDF »

Host cell Ca2+ and protein kinase C regulate innate recognition of Toxoplasma gondii.

K. S. Masek, J. Fiore, M. Leitges, S.-F. Yan, B. D. Freedman, and C. A. Hunter (2006)
J. Cell Sci. 119, 4565-4573
 |  Abstract »  |  Full Text »  |  PDF »

Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii.

J. Mazumdar, E. H. Wilson, K. Masek, C. A. Hunter, and B. Striepen (2006)
PNAS 103, 13192-13197
 |  Abstract »  |  Full Text »  |  PDF »

Toxoplasma gondii Genotype Determines MyD88-Dependent Signaling in Infected Macrophages.

L. Kim, B. A. Butcher, C. W. Lee, S. Uematsu, S. Akira, and E. Y. Denkers (2006)
J. Immunol. 177, 2584-2591
 |  Abstract »  |  Full Text »  |  PDF »

cDNA Microarray Analysis of Host-Pathogen Interactions in a Porcine In Vitro Model for Toxoplasma gondii Infection.

M. Okomo-Adhiambo, C. Beattie, and A. Rink (2006)
Infect. Immun. 74, 4254-4265
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Restrains In Vivo Growth of Toxoplasma gondii Independently of Gamma Interferon.

C. S. Subauste and M. Wessendarp (2006)
Infect. Immun. 74, 1573-1579
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-{gamma} Signaling.

S. Zimmermann, P. J. Murray, K. Heeg, and A. H. Dalpke (2006)
J. Immunol. 176, 1840-1847
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon Blocks Gammaherpesvirus Reactivation from Latency.

A. L. Steed, E. S. Barton, S. A. Tibbetts, D. L. Popkin, M. L. Lutzke, R. Rochford, and H. W. Virgin IV (2006)
J. Virol. 80, 192-200
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A Requirement for the V{gamma}1+ Subset of Peripheral {gamma}{delta} T Cells in the Control of the Systemic Growth of Toxoplasma gondii and Infection-Induced Pathology.

C. E. Egan, J. E. Dalton, E. M. Andrew, J. E. Smith, M.-J. Gubbels, B. Striepen, and S. R. Carding (2005)
J. Immunol. 175, 8191-8199
 |  Abstract »  |  Full Text »  |  PDF »

Toxoplasma gondii-Specific Immunoglobulin M Limits Parasite Dissemination by Preventing Host Cell Invasion.

K. N. Couper, C. W. Roberts, F. Brombacher, J. Alexander, and L. L. Johnson (2005)
Infect. Immun. 73, 8060-8068
 |  Abstract »  |  Full Text »  |  PDF »

Toxoplasma gondii Prevents Neuron Degeneration by Interferon-{gamma}-Activated Microglia in a Mechanism Involving Inhibition of Inducible Nitric Oxide Synthase and Transforming Growth Factor-{beta}1 Production by Infected Microglia.

C. Rozenfeld, R. Martinez, S. Seabra, C. Sant'Anna, J. G. R. Goncalves, M. Bozza, V. Moura-Neto, and W. De Souza (2005)
Am. J. Pathol. 167, 1021-1031
 |  Abstract »  |  Full Text »  |  PDF »

Salmonella Pathogenicity Island 2-Dependent Expression of Suppressor of Cytokine Signaling 3 in Macrophages.

K.-i. Uchiya and T. Nikai (2005)
Infect. Immun. 73, 5587-5594
 |  Abstract »  |  Full Text »  |  PDF »

Exacerbated Susceptibility to Infection-Stimulated Immunopathology in CD1d-Deficient Mice.

S. T. Smiley, P. A. Lanthier, K. N. Couper, F. M. Szaba, J. E. Boyson, W. Chen, and L. L. Johnson (2005)
J. Immunol. 174, 7904-7911
 |  Abstract »  |  Full Text »  |  PDF »

Stage-Specific Expression of Surface Antigens by Toxoplasma gondii as a Mechanism to Facilitate Parasite Persistence.

S.-K. Kim and J. C. Boothroyd (2005)
J. Immunol. 174, 8038-8048
 |  Abstract »  |  Full Text »  |  PDF »

Recruitment of Gr-1+ monocytes is essential for control of acute toxoplasmosis.

P. M. Robben, M. LaRegina, W. A. Kuziel, and L. D. Sibley (2005)
J. Exp. Med. 201, 1761-1769
 |  Abstract »  |  Full Text »  |  PDF »

p47 GTPases Regulate Toxoplasma gondii Survival in Activated Macrophages.

B. A. Butcher, R. I. Greene, S. C. Henry, K. L. Annecharico, J. B. Weinberg, E. Y. Denkers, A. Sher, and G. A. Taylor (2005)
Infect. Immun. 73, 3278-3286
 |  Abstract »  |  Full Text »  |  PDF »

Class I Major Histocompatibility Complex Presentation of Antigens That Escape from the Parasitophorous Vacuole of Toxoplasma gondii.

M.-J. Gubbels, B. Striepen, N. Shastri, M. Turkoz, and E. A. Robey (2005)
Infect. Immun. 73, 703-711
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon Does Not Enhance Clearance of Pseudomonas aeruginosa but Does Amplify a Proinflammatory Response in a Murine Model of Postseptic Immunosuppression.

E. D. Murphey, D. N. Herndon, and E. R. Sherwood (2004)
Infect. Immun. 72, 6892-6901
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of the Growth of Toxoplasma gondii in Immature Human Dendritic Cells Is Dependent on the Expression of TNF-{alpha} Receptor 2.

A. Giese, S. Stuhlsatz, W. Daubener, and C. R. MacKenzie (2004)
J. Immunol. 173, 3366-3374
 |  Abstract »  |  Full Text »  |  PDF »

Functional Inactivation of Immature Dendritic Cells by the Intracellular Parasite Toxoplasma gondii.

A. S. McKee, F. Dzierszinski, M. Boes, D. S. Roos, and E. J. Pearce (2004)
J. Immunol. 173, 2632-2640
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant GRA4 or ROP2 Protein Combined with Alum or the gra4 Gene Provides Partial Protection in Chronic Murine Models of Toxoplasmosis.

V. Martin, A. Supanitsky, P. C. Echeverria, S. Litwin, T. Tanos, A. R. De Roodt, E. A. Guarnera, and S. O. Angel (2004)
Clin. Vaccine Immunol. 11, 704-710
 |  Abstract »  |  Full Text »

Involvement of Salmonella Pathogenicity Island 2 in the Up-Regulation of Interleukin-10 Expression in Macrophages: Role of Protein Kinase A Signal Pathway.

K.-i. Uchiya, E. A. Groisman, and T. Nikai (2004)
Infect. Immun. 72, 1964-1973
 |  Abstract »  |  Full Text »  |  PDF »

Transient hypogonadotrophic hypogonadism in males with acute toxoplasmosis: suppressive effect of interleukin-1{beta} on the secretion of GnRH.

C. Oktenli, L. Doganci, T. Ozgurtas, R.E. Araz, M. Tanyuksel, U. Musabak, S.Y. Sanisoglu, Z. Yesilova, M.K. Erbil, and A. Inal (2004)
Hum. Reprod. 19, 859-866
 |  Abstract »  |  Full Text »  |  PDF »

Production of IL-12 by Macrophages Infected with Toxoplasma gondii Depends on the Parasite Genotype.

P. M. Robben, D. G. Mordue, S. M. Truscott, K. Takeda, S. Akira, and L. D. Sibley (2004)
J. Immunol. 172, 3686-3694
 |  Abstract »  |  Full Text »  |  PDF »

Intact type 1 immunity and immune-associated coagulative responses in mice lacking IFN{gamma}-inducible fibrinogen-like protein 2.

W. W. Hancock, F. M. Szaba, K. N. Berggren, M. A. Parent, I. K. Mullarky, J. Pearl, A. M. Cooper, K. H. Ely, D. L. Woodland, I.-J. Kim, et al. (2004)
PNAS 101, 3005-3010
 |  Abstract »  |  Full Text »  |  PDF »

STAT1 Is Essential for Antimicrobial Effector Function but Dispensable for Gamma Interferon Production during Toxoplasma gondii Infection.

L. C. Gavrilescu, B. A. Butcher, L. Del Rio, G. A. Taylor, and E. Y. Denkers (2004)
Infect. Immun. 72, 1257-1264
 |  Abstract »  |  Full Text »  |  PDF »

Role of NK Cells and Gamma Interferon in Transplacental Passage of Toxoplasma gondii in a Mouse Model of Primary Infection.

A. Abou-Bacar, A. W. Pfaff, S. Georges, V. Letscher-Bru, D. Filisetti, O. Villard, E. Antoni, J.-P. Klein, and E. Candolfi (2004)
Infect. Immun. 72, 1397-1401
 |  Abstract »  |  Full Text »  |  PDF »

Toxoplasma gondii Interferes with Lipopolysaccharide-Induced Mitogen-Activated Protein Kinase Activation by Mechanisms Distinct from Endotoxin Tolerance.

L. Kim, B. A. Butcher, and E. Y. Denkers (2004)
J. Immunol. 172, 3003-3010
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{gamma}: an overview of signals, mechanisms and functions.

K. Schroder, P. J. Hertzog, T. Ravasi, and D. A. Hume (2004)
J. Leukoc. Biol. 75, 163-189
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-10 and Pathogenesis of Murine Ocular Toxoplasmosis.

F. Lu, S. Huang, and L. H. Kasper (2003)
Infect. Immun. 71, 7159-7163
 |  Abstract »  |  Full Text »  |  PDF »

A novel population of Gr-1+-activated macrophages induced during acute toxoplasmosis.

D. G. Mordue and L. D. Sibley (2003)
J. Leukoc. Biol. 74, 1015-1025
 |  Abstract »  |  Full Text »

Role of Cytokines and Major Histocompatibility Complex Restriction in Mouse Resistance to Infection with a Natural Recombinant Strain (Type I-III) of Toxoplasma gondii.

B. Fux, C. V. Rodrigues, R. W. Portela, N. M. Silva, C. Su, D. Sibley, R. W. A. Vitor, and R. T. Gazzinelli (2003)
Infect. Immun. 71, 6392-6401
 |  Abstract »  |  Full Text »  |  PDF »

Vaccination with Toxoplasma gondii SAG-1 Protein Is Protective against Congenital Toxoplasmosis in BALB/c Mice but Not in CBA/J Mice.

V. Letscher-Bru, A. W. Pfaff, A. Abou-Bacar, D. Filisetti, E. Antoni, O. Villard, J.-P. Klein, and E. Candolfi (2003)
Infect. Immun. 71, 6615-6619
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma}-Regulated Toxoplasma gondii Distribution and Load in the Murine Eye.

K. Norose, H.-S. Mun, F. Aosai, M. Chen, L.-X. Piao, M. Kobayashi, Y. Iwakura, and A. Yano (2003)
Invest. Ophthalmol. Vis. Sci. 44, 4375-4381
 |  Abstract »  |  Full Text »  |  PDF »

Both Lymphotoxin-{alpha} and TNF Are Crucial for Control of Toxoplasma gondii in the Central Nervous System.

D. Schluter, L.-Y. Kwok, S. Lutjen, S. Soltek, S. Hoffmann, H. Korner, and M. Deckert (2003)
J. Immunol. 170, 6172-6182
 |  Abstract »  |  Full Text »  |  PDF »

Neospora caninum-Infected Cattle Develop Parasite-Specific CD4+ Cytotoxic T Lymphocytes.

L. M. Staska, T. C. McGuire, C. J. Davies, H. A. Lewin, and T. V. Baszler (2003)
Infect. Immun. 71, 3272-3279
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-12 p40- and Fas Ligand-Dependent Apoptotic Pathways Involving STAT-1 Phosphorylation Are Triggered during Infection with a Virulent Strain of Toxoplasma gondii.

L. C. Gavrilescu and E. Y. Denkers (2003)
Infect. Immun. 71, 2577-2583
 |  Abstract »  |  Full Text »  |  PDF »

Soluble Factors Released by Toxoplasma gondii-Infected Astrocytes Down-Modulate Nitric Oxide Production by Gamma Interferon-Activated Microglia and Prevent Neuronal Degeneration.

C. Rozenfeld, R. Martinez, R. T. Figueiredo, M. T. Bozza, F. R. S. Lima, A. L. Pires, P. M. Silva, A. Bonomo, J. Lannes-Vieira, W. De Souza, et al. (2003)
Infect. Immun. 71, 2047-2057
 |  Abstract »  |  Full Text »

Fibrin-mediated Protection Against Infection-stimulated Immunopathology.

L. L. Johnson, K. N. Berggren, F. M. Szaba, W. Chen, and S. T. Smiley (2003)
J. Exp. Med. 197, 801-806
 |  Abstract »  |  Full Text »  |  PDF »

The Induction and Kinetics of Antigen-Specific CD8 T Cells Are Defined by the Stage Specificity and Compartmentalization of the Antigen in Murine Toxoplasmosis.

L.-Y. Kwok, S. Lutjen, S. Soltek, D. Soldati, D. Busch, M. Deckert, and D. Schluter (2003)
J. Immunol. 170, 1949-1957
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The Function of Gamma Interferon-Inducible GTP-Binding Protein IGTP in Host Resistance to Toxoplasma gondii Is Stat1 Dependent and Requires Expression in Both Hematopoietic and Nonhematopoietic Cellular Compartments.

C. M. Collazo, G. S. Yap, S. Hieny, P. Caspar, C. G. Feng, G. A. Taylor, and A. Sher (2002)
Infect. Immun. 70, 6933-6939
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of Interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 Ligand Pathways to the Development of a Pathological T-Cell Response in IL-10-Deficient Mice.

U. Wille, E. N. Villegas, L. Craig, R. Peach, and C. A. Hunter (2002)
Infect. Immun. 70, 6940-6947
 |  Abstract »  |  Full Text »  |  PDF »

A Role for Inducible Costimulator Protein in the CD28- Independent Mechanism of Resistance to Toxoplasma gondii.

E. N. Villegas, L. A. Lieberman, N. Mason, S. L. Blass, V. P. Zediak, R. Peach, T. Horan, S. Yoshinaga, and C. A. Hunter (2002)
J. Immunol. 169, 937-943
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro Correlates of Ld-Restricted Resistance to Toxoplasmic Encephalitis and Their Critical Dependence on Parasite Strain.

J. J. Johnson, C. W. Roberts, C. Pope, F. Roberts, M. J. Kirisits, R. Estes, E. Mui, T. Krieger, C. R. Brown, J. Forman, et al. (2002)
J. Immunol. 169, 966-973
 |  Abstract »  |  Full Text »  |  PDF »

Phenotype and Regulation of Persistent Intracerebral T Cells in Murine Toxoplasma Encephalitis.

D. Schluter, T. Meyer, L.-Y. Kwok, M. Montesinos-Rongen, S. Lutjen, A. Strack, M. L. Schmitz, and M. Deckert (2002)
J. Immunol. 169, 315-322
 |  Abstract »  |  Full Text »  |  PDF »

Treatment with Soluble Interleukin-15R{alpha} Exacerbates Intracellular Parasitic Infection by Blocking the Development of Memory CD8+ T Cell Response.

I. A. Khan, M. Moretto, X.-q. Wei, M. Williams, J. D. Schwartzman, and F. Y. Liew (2002)
J. Exp. Med. 195, 1463-1470
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of a Cyclic GMP-Dependent Protein Kinase Inhibitor in Treatment of Murine Toxoplasmosis: Gamma Interferon Is Required for Efficacy.

B. Nare, J. J. Allocco, P. A. Liberator, and R. G. K. Donald (2002)
Antimicrob. Agents Chemother. 46, 300-307
 |  Abstract »  |  Full Text »  |  PDF »

L-Tryptophan-L-Kynurenine Pathway Metabolism Accelerated by Toxoplasmagondii Infection Is Abolished in Gamma Interferon-Gene-Deficient Mice: Cross-Regulation between Inducible Nitric Oxide Synthase and Indoleamine-2,3-Dioxygenase.

S. Fujigaki, K. Saito, M. Takemura, N. Maekawa, Y. Yamada, H. Wada, and M. Seishima (2002)
Infect. Immun. 70, 779-786
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Indoleamine 2,3-Dioxygenase, Tryptophan Degradation, and Kynurenine Formation during In Vivo Infection with Toxoplasma gondii: Induction by Endogenous Gamma Interferon and Requirement of Interferon Regulatory Factor 1.

N. M. Silva, C. V. Rodrigues, M. M. Santoro, L. F. L. Reis, J. I. Alvarez-Leite, and R. T. Gazzinelli (2002)
Infect. Immun. 70, 859-868
 |  Abstract »  |  Full Text »  |  PDF »

Deficient Humoral Responses Underlie Susceptibility to Toxoplasma gondii in CD4-Deficient Mice.

L. L. Johnson and P. C. Sayles (2002)
Infect. Immun. 70, 185-191
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Toxoplasma gondii-Specific T Cells Recovered from Vitreous Fluid of Patients with Ocular Toxoplasmosis.

E. J. Feron, V. N. A. Klaren, E. A. Wierenga, G. M. G. M. Verjans, and A. Kijlstra (2001)
Invest. Ophthalmol. Vis. Sci. 42, 3228-3232
 |  Abstract »  |  Full Text »  |  PDF »

CXCR2 Deficiency Confers Impaired Neutrophil Recruitment and Increased Susceptibility During Toxoplasma gondii Infection.

L. Del Rio, S. Bennouna, J. Salinas, and E. Y. Denkers (2001)
J. Immunol. 167, 6503-6509
 |  Abstract »  |  Full Text »  |  PDF »

Acute Toxoplasmosis Leads to Lethal Overproduction of Th1 Cytokines.

D. G. Mordue, F. Monroy, M. La Regina, C. A. Dinarello, and L. D. Sibley (2001)
J. Immunol. 167, 4574-4584
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon-Induced Inhibition of Toxoplasma gondii in Astrocytes Is Mediated by IGTP.

S. K. Halonen, G. A. Taylor, and L. M. Weiss (2001)
Infect. Immun. 69, 5573-5576
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Apoptosis and Interferon-{gamma} in Murine Toxoplasmosis.

D. F. Shen, D. M. Matteson, N. Tuaillon, B. K. Suedekum, R. R. Buggage, and C.-C. Chan (2001)
Invest. Ophthalmol. Vis. Sci. 42, 2031-2036
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{{gamma}} Overproduction and High Level Apoptosis Are Associated with High but Not Low Virulence Toxoplasma gondii Infection.

L. C. Gavrilescu and E. Y. Denkers (2001)
J. Immunol. 167, 902-909
 |  Abstract »  |  Full Text »  |  PDF »

A Role for CD44 in the Production of IFN-{{gamma}} and Immunopathology During Infection with Toxoplasma gondii.

S. L. Blass, E. Pure, and C. A. Hunter (2001)
J. Immunol. 166, 5726-5732
 |  Abstract »  |  Full Text »  |  PDF »

Immunological Studies of Chronic Ocular Toxoplasmosis: Up-Regulation of Major Histocompatibility Complex Class I and Transforming Growth Factor {beta} and a Protective Role for Interleukin-6.

R. E. Lyons, J. P. Anthony, D. J. P. Ferguson, N. Byrne, J. Alexander, F. Roberts, and C. W. Roberts (2001)
Infect. Immun. 69, 2589-2595
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Interleukin-12 Promotes Pathologic Liver Changes and Death in Mice Coinfected with Schistosoma mansoni and Toxoplasma gondii.

M. I. Araujo, S. K. Bliss, Y. Suzuki, A. Alcaraz, E. Y. Denkers, and E. J. Pearce (2001)
Infect. Immun. 69, 1454-1462
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Intranasal Immunization with SAG1 and Nontoxic Mutant Heat-Labile Enterotoxins Protects Mice against Toxoplasma gondii.

C. Bonenfant, I. Dimier-Poisson, F. Velge-Roussel, D. Buzoni-Gatel, G. Del Giudice, R. Rappuoli, and D. Bout (2001)
Infect. Immun. 69, 1605-1612
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In Vitro Investigation of Host Resistance to Toxoplasma gondii Infection in Microglia of BALB/c and CBA/Ca Mice.

Y. R. Freund, N. T. Zaveri, and H. S. Javitz (2001)
Infect. Immun. 69, 765-772
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Mice Lacking the Chemokine Receptor CCR1 Show Increased Susceptibility to Toxoplasma gondii Infection.

I. A. Khan, P. M. Murphy, L. Casciotti, J. D. Schwartzman, J. Collins, J.-L. Gao, and G. R. Yeaman (2001)
J. Immunol. 166, 1930-1937
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Interleukin-18 (IL-18) Enhances Innate IL-12-Mediated Resistance to Toxoplasma gondii.

G. Cai, R. Kastelein, and C. A. Hunter (2000)
Infect. Immun. 68, 6932-6938
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Identification of STAT4-Dependent and Independent Mechanisms of Resistance to Toxoplasma gondii.

G. Cai, T. Radzanowski, E. N. Villegas, R. Kastelein, and C. A. Hunter (2000)
J. Immunol. 165, 2619-2627
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Recombinant Attenuated Toxoplasma gondii Expressing the Plasmodium yoelii Circumsporozoite Protein Provides Highly Effective Priming for CD8+ T Cell-Dependent Protective Immunity Against Malaria.

H. Charest, M. Sedegah, G. S. Yap, R. T. Gazzinelli, P. Caspar, S. L. Hoffman, and A. Sher (2000)
J. Immunol. 165, 2084-2092
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Differential Infectivity and Division of Toxoplasma gondii in Human Peripheral Blood Leukocytes.

J. Y. Channon, R. M. Seguin, and L. H. Kasper (2000)
Infect. Immun. 68, 4822-4826
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Human Dendritic Cells Discriminate Between Viable and Killed Toxoplasma gondii Tachyzoites: Dendritic Cell Activation After Infection with Viable Parasites Results in CD28 and CD40 Ligand Signaling That Controls IL-12-Dependent and -Independent T Cell Production of IFN-{gamma}.

C. S. Subauste and M. Wessendarp (2000)
J. Immunol. 165, 1498-1505
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IL-10 Is Required for Prevention of Necrosis in the Small Intestine and Mortality in Both Genetically Resistant BALB/c and Susceptible C57BL/6 Mice Following Peroral Infection with Toxoplasma gondii.

Y. Suzuki, A. Sher, G. Yap, D. Park, L. E. Neyer, O. Liesenfeld, M. Fort, H. Kang, and E. Gufwoli (2000)
J. Immunol. 164, 5375-5382
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T Cell Clones Raised from Chronically Infected Healthy Humans by Stimulation with Toxoplasma gondii Excretory-Secretory Antigens Cross-React with Live Tachyzoites: Characterization of the Fine Antigenic Specificity of the Clones and Implications for Vaccine Development.

I. Prigione, P. Facchetti, L. Lecordier, D. Deslee, S. Chiesa, M.-F. Cesbron-Delauw, and V. Pistoia (2000)
J. Immunol. 164, 3741-3748
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B Cells Are Essential for Vaccination-Induced Resistance to Virulent Toxoplasma gondii.

P. C. Sayles, G. W. Gibson, and L. L. Johnson (2000)
Infect. Immun. 68, 1026-1033
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The CD40/CD40 Ligand Interaction Is Required for Resistance to Toxoplasmic Encephalitis.

G. Reichmann, W. Walker, E. N. Villegas, L. Craig, G. Cai, J. Alexander, and C. A. Hunter (2000)
Infect. Immun. 68, 1312-1318
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Decreased Resistance of B Cell-Deficient Mice to Infection with Toxoplasma gondii Despite Unimpaired Expression of IFN-{gamma}, TNF-{alpha}, and Inducible Nitric Oxide Synthase.

H. Kang, J. S. Remington, and Y. Suzuki (2000)
J. Immunol. 164, 2629-2634
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Immune CD8+ T Cells Prevent Reactivation of Toxoplasma gondii Infection in the Immunocompromised Host.

I. A. Khan, W. R. Green, L. H. Kasper, K. A. Green, and J. D. Schwartzman (1999)
Infect. Immun. 67, 5869-5876
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The NF-{kappa}B Family Member RelB Is Required for Innate and Adaptive Immunity to Toxoplasma gondii.

J. Caamano, J. Alexander, L. Craig, R. Bravo, and C. A. Hunter (1999)
J. Immunol. 163, 4453-4461
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IL-15 Prolongs the Duration of CD8+ T Cell-Mediated Immunity in Mice Infected with a Vaccine Strain of Toxoplasma gondii.

I. A. Khan and L. Casciotti (1999)
J. Immunol. 163, 4503-4509
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Role of CD28 in the Generation of Effector and Memory Responses Required for Resistance to Toxoplasma gondii.

E. N. Villegas, M. M. Elloso, G. Reichmann, R. Peach, and C. A. Hunter (1999)
J. Immunol. 163, 3344-3353
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The CD28/B7 Interaction Is Not Required for Resistance to Toxoplasma gondii in the Brain but Contributes to the Development of Immunopathology.

G. Reichmann, E. N. Villegas, L. Craig, R. Peach, and C. A. Hunter (1999)
J. Immunol. 163, 3354-3362
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Toxoplasma gondii and Schistosoma mansoni Synergize to Promote Hepatocyte Dysfunction Associated with High Levels of Plasma TNF-{alpha} and Early Death in C57BL/6 Mice.

A. J. Marshall, L. R. Brunet, Y. van Gessel, A. Alcaraz, S. K. Bliss, E. J. Pearce, and E. Y. Denkers (1999)
J. Immunol. 163, 2089-2097
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