Science 15 April 1988: Vol. 240. no. 4850, pp. 324 - 326 DOI: 10.1126/science.3353726

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Articles

Susceptibility to Autoimmunity and B Cell Resistance to Apoptosis in Mice Lacking Androgen Receptor in B Cells.

S. Altuwaijri, K.-H. Chuang, K.-P. Lai, J.-J. Lai, H.-Y. Lin, F. M. Young, A. Bottaro, M.-Y. Tsai, W.-P. Zeng, H.-C. Chang, et al. (2009)
Mol. Endocrinol. 23, 444-453
 |  Abstract »  |  Full Text »  |  PDF »

Androgen Receptor Roles in Spermatogenesis and Fertility: Lessons from Testicular Cell-Specific Androgen Receptor Knockout Mice.

R.-S. Wang, S. Yeh, C.-R. Tzeng, and C. Chang (2009)
Endocr. Rev. 30, 119-132
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth.

Z. Guo, X. Yang, F. Sun, R. Jiang, D. E. Linn, H. Chen, H. Chen, X. Kong, J. Melamed, C. G. Tepper, et al. (2009)
Cancer Res. 69, 2305-2313
 |  Abstract »  |  Full Text »  |  PDF »

APPL1: role in adiponectin signaling and beyond.

S. S. Deepa and L. Q. Dong (2009)
Am J Physiol Endocrinol Metab 296, E22-E36
 |  Abstract »  |  Full Text »  |  PDF »

Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.

Y. Dai, D. Ngo, J. Jacob, L. W. Forman, and D. V. Faller (2008)
Carcinogenesis 29, 1725-1733
 |  Abstract »  |  Full Text »  |  PDF »

Androgen receptor is a tumor suppressor and proliferator in prostate cancer.

Y. Niu, S. Altuwaijri, K.-P. Lai, C.-T. Wu, W. A. Ricke, E. M. Messing, J. Yao, S. Yeh, and C. Chang (2008)
PNAS 105, 12182-12187
 |  Abstract »  |  Full Text »  |  PDF »

Comparison of bone mineral density and body proportions between women with complete androgen insensitivity syndrome and women with gonadal dysgenesis.

T S Han, D Goswami, S Trikudanathan, S M Creighton, and G S Conway (2008)
Eur. J. Endocrinol. 159, 179-185
 |  Abstract »  |  Full Text »  |  PDF »

Expression of a hyperactive androgen receptor leads to androgen-independent growth of prostate cancer cells.

C.-L. Hsieh, C. Cai, A. Giwa, A. Bivins, S.-Y. Chen, D. Sabry, K. Govardhan, and L. Shemshedini (2008)
J. Mol. Endocrinol. 41, 13-23
 |  Abstract »  |  Full Text »  |  PDF »

Androgen Receptor Gene CAG Repeat Polymorphism and X-Chromosome Inactivation in Children with Premature Adrenarche.

S. Lappalainen, P. Utriainen, T. Kuulasmaa, R. Voutilainen, and J. Jaaskelainen (2008)
J. Clin. Endocrinol. Metab. 93, 1304-1309
 |  Abstract »  |  Full Text »  |  PDF »

Using the Protein Chip to Screen Agonists and Antagonists of the Androgen Receptor.

Y. Zhou, A. Liu, W. Wang, and G. Du (2008)
J Biomol Screen 13, 276-284
 |  Abstract »  |  PDF »

Hormonal Regulation of Testicular Steroid and Cholesterol Homeostasis.

S. M. Eacker, N. Agrawal, K. Qian, H. L. Dichek, E.-Y. Gong, K. Lee, and R. E. Braun (2008)
Mol. Endocrinol. 22, 623-635
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin D3/CDK11p58 Complex Is Involved in the Repression of Androgen Receptor.

H. Zong, Y. Chi, Y. Wang, Y. Yang, L. Zhang, H. Chen, J. Jiang, Z. Li, Y. Hong, H. Wang, et al. (2007)
Mol. Cell. Biol. 27, 7125-7142
 |  Abstract »  |  Full Text »  |  PDF »

Cell- and gene-specific regulation of primary target genes by the androgen receptor.

E. C. Bolton, A. Y. So, C. Chaivorapol, C. M. Haqq, H. Li, and K. R. Yamamoto (2007)
Genes & Dev. 21, 2005-2017
 |  Abstract »  |  Full Text »  |  PDF »

Sirtuin 1 Is Required for Antagonist-Induced Transcriptional Repression of Androgen-Responsive Genes by the Androgen Receptor.

Y. Dai, D. Ngo, L. W. Forman, D. C. Qin, J. Jacob, and D. V. Faller (2007)
Mol. Endocrinol. 21, 1807-1821
 |  Abstract »  |  Full Text »  |  PDF »

ETV1 Is a Novel Androgen Receptor-Regulated Gene that Mediates Prostate Cancer Cell Invasion.

C. Cai, C.-L. Hsieh, J. Omwancha, Z. Zheng, S.-Y. Chen, J.-L. Baert, and L. Shemshedini (2007)
Mol. Endocrinol. 21, 1835-1846
 |  Abstract »  |  Full Text »  |  PDF »

ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells.

H. Kikuchi, C. Uchida, T. Hattori, T. Isobe, Y. Hiramatsu, K. Kitagawa, T. Oda, H. Konno, and M. Kitagawa (2007)
Carcinogenesis 28, 1752-1758
 |  Abstract »  |  Full Text »  |  PDF »

Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor.

C.-T. Wu, S. Altuwaijri, W. A. Ricke, S.-P. Huang, S. Yeh, C. Zhang, Y. Niu, M.-Y. Tsai, and C. Chang (2007)
PNAS 104, 12679-12684
 |  Abstract »  |  Full Text »  |  PDF »

c-Jun Has Multiple Enhancing Activities in the Novel Cross Talk between the Androgen Receptor and Ets Variant Gene 1 in Prostate Cancer.

C. Cai, C.-L. Hsieh, and L. Shemshedini (2007)
Mol. Cancer Res. 5, 725-735
 |  Abstract »  |  Full Text »  |  PDF »

Promotion of Bladder Cancer Development and Progression by Androgen Receptor Signals.

H. Miyamoto, Z. Yang, Y.-T. Chen, H. Ishiguro, H. Uemura, Y. Kubota, Y. Nagashima, Y.-J. Chang, Y.-C. Hu, M.-Y. Tsai, et al. (2007)
J Natl Cancer Inst 99, 558-568
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Androgen Receptor Transactivation and Prostate Cancer Cell Growth by Heterogeneous Nuclear Ribonucleoprotein A1 via Interaction with Androgen Receptor Coregulator ARA54.

Z. Yang, Y.-J. Chang, H. Miyamoto, S. Yeh, J. L. Yao, P. A. di Sant'Agnese, M.-Y. Tsai, and C. Chang (2007)
Endocrinology 148, 1340-1349
 |  Abstract »  |  Full Text »  |  PDF »

Transgelin Functions as a Suppressor via Inhibition of ARA54-Enhanced Androgen Receptor Transactivation and Prostate Cancer Cell Growth.

Z. Yang, Y.-J. Chang, H. Miyamoto, J. Ni, Y. Niu, Z. Chen, Y.-L. Chen, J. L. Yao, P. A. di Sant'Agnese, and C. Chang (2007)
Mol. Endocrinol. 21, 343-358
 |  Abstract »  |  Full Text »  |  PDF »

Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells.

M.-Y. Tsai, S.-D. Yeh, R.-S. Wang, S. Yeh, C. Zhang, H.-Y. Lin, C.-R. Tzeng, and C. Chang (2006)
PNAS 103, 18975-18980
 |  Abstract »  |  Full Text »  |  PDF »

International Union of Pharmacology. LXV. The Pharmacology and Classification of the Nuclear Receptor Superfamily: Glucocorticoid, Mineralocorticoid, Progesterone, and Androgen Receptors.

N. Z. Lu, S. E. Wardell, K. L. Burnstein, D. Defranco, P. J. Fuller, V. Giguere, R. B. Hochberg, L. McKay, J.-M. Renoir, N. L. Weigel, et al. (2006)
Pharmacol. Rev. 58, 782-797
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Androgen Receptor in Sertoli Cell Is Essential for Germ Cell Nursery and Junctional Complex Formation in Mouse Testes.

R.-S. Wang, S. Yeh, L.-M. Chen, H.-Y. Lin, C. Zhang, J. Ni, C.-C. Wu, P. A. di Sant'Agnese, K. L. deMesy-Bentley, C.-R. Tzeng, et al. (2006)
Endocrinology 147, 5624-5633
 |  Abstract »  |  Full Text »  |  PDF »

Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells.

C. Zhang, S. Yeh, Y.-T. Chen, C.-C. Wu, K.-H. Chuang, H.-Y. Lin, R.-S. Wang, Y.-J. Chang, C. Mendis-Handagama, L. Hu, et al. (2006)
PNAS 103, 17718-17723
 |  Abstract »  |  Full Text »  |  PDF »

DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.

H. Le, J. T. Arnold, K. K. McFann, and M. R. Blackman (2006)
Am J Physiol Endocrinol Metab 290, E952-E960
 |  Abstract »  |  Full Text »  |  PDF »

Steroid Receptor Regulation of Epidermal Growth Factor Signaling through Src in Breast and Prostate Cancer Cells: Steroid Antagonist Action.

A. Migliaccio, M. Di Domenico, G. Castoria, M. Nanayakkara, M. Lombardi, A. de Falco, A. Bilancio, L. Varricchio, A. Ciociola, and F. Auricchio (2005)
Cancer Res. 65, 10585-10593
 |  Abstract »  |  Full Text »  |  PDF »

Differential expression of p160 steroid receptor coactivators in the rat testis and epididymis.

J. Igarashi-Migitaka, A. Takeshita, N. Koibuchi, S. Yamada, R. Ohtani-Kaneko, and K. Hirata (2005)
Eur. J. Endocrinol. 153, 595-604
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Androgen Receptor Expression by Phosphatidylinositol 3-Kinase/Akt Downstream Substrate, FOXO3a, and Their Roles in Apoptosis of LNCaP Prostate Cancer Cells.

L. Yang, S. Xie, Md. S. Jamaluddin, S. Altuwaijri, J. Ni, E. Kim, Y.-T. Chen, Y.-C. Hu, L. Wang, K.-H. Chuang, et al. (2005)
J. Biol. Chem. 280, 33558-33565
 |  Abstract »  |  Full Text »  |  PDF »

Leukocyte Populations and Steroid Receptor Expression in Human First-Trimester Decidua; Regulation by Antiprogestin and Prostaglandin E Analog.

S. A. Milne, T. A. Henderson, R. W. Kelly, P. T. Saunders, D. T. Baird, and H. O. D. Critchley (2005)
J. Clin. Endocrinol. Metab. 90, 4315-4321
 |  Abstract »  |  Full Text »  |  PDF »

Insulin and Leptin Resistance With Hyperleptinemia in Mice Lacking Androgen Receptor.

H.-Y. Lin, Q. Xu, S. Yeh, R.-S. Wang, J. D. Sparks, and C. Chang (2005)
Diabetes 54, 1717-1725
 |  Abstract »  |  Full Text »  |  PDF »

9-cis-Retinoic Acid Inhibits Androgen Receptor Activity through Activation of Retinoid X Receptor.

K.-H. Chuang, Y.-F. Lee, W.-J. Lin, C.-Y. Chu, S. Altuwaijri, Y.-J. Y. Wan, and C. Chang (2005)
Mol. Endocrinol. 19, 1200-1212
 |  Abstract »  |  Full Text »  |  PDF »

Recruitment of the Androgen Receptor via Serum Response Factor Facilitates Expression of a Myogenic Gene.

S. Vlahopoulos, W. E. Zimmer, G. Jenster, N. S. Belaguli, S. P. Balk, A. O. Brinkmann, R. B. Lanz, V. C. Zoumpourlis, and R. J. Schwartz (2005)
J. Biol. Chem. 280, 7786-7792
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin D1 Binding to the Androgen Receptor (AR) NH2-Terminal Domain Inhibits Activation Function 2 Association and Reveals Dual Roles for AR Corepression.

C. J. Burd, C. E. Petre, H. Moghadam, E. M. Wilson, and K. E. Knudsen (2005)
Mol. Endocrinol. 19, 607-620
 |  Abstract »  |  Full Text »  |  PDF »

Heregulin-Induced Activation of HER2 and HER3 Increases Androgen Receptor Transactivation and CWR-R1 Human Recurrent Prostate Cancer Cell Growth.

C. W. Gregory, Y. E. Whang, W. McCall, X. Fei, Y. Liu, L. A. Ponguta, F. S. French, E. M. Wilson, and H. S. Earp III (2005)
Clin. Cancer Res. 11, 1704-1712
 |  Abstract »  |  Full Text »  |  PDF »

Androgen Receptor (AR) NH2- and COOH-Terminal Interactions Result in the Differential Influences on the AR-Mediated Transactivation and Cell Growth.

C.-L. Hsu, Y.-L. Chen, H.-J. Ting, W.-J. Lin, Z. Yang, Y. Zhang, L. Wang, C.-T. Wu, H.-C. Chang, S. Yeh, et al. (2005)
Mol. Endocrinol. 19, 350-361
 |  Abstract »  |  Full Text »  |  PDF »

Nonsteroidal Selective Androgen Receptors Modulators (SARMs): Designer Androgens with Flexible Structures Provide Clinical Promise.

T. R. Brown (2004)
Endocrinology 145, 5417-5419
 |  Full Text »  |  PDF »

Regulation of Androgen Receptor Signaling by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10) Tumor Suppressor through Distinct Mechanisms in Prostate Cancer Cells.

H.-K. Lin, Y.-C. Hu, D. K. Lee, and C. Chang (2004)
Mol. Endocrinol. 18, 2409-2423
 |  Abstract »  |  Full Text »  |  PDF »

Functional Domain and Motif Analyses of Androgen Receptor Coregulator ARA70 and Its Differential Expression in Prostate Cancer.

Y.-C. Hu, S. Yeh, S.-D. Yeh, E. R. Sampson, J. Huang, P. Li, C.-L. Hsu, H.-J. Ting, H.-K. Lin, L. Wang, et al. (2004)
J. Biol. Chem. 279, 33438-33446
 |  Abstract »  |  Full Text »  |  PDF »

Subfertility and defective folliculogenesis in female mice lacking androgen receptor.

Y.-C. Hu, P.-H. Wang, S. Yeh, R.-S. Wang, C. Xie, Q. Xu, X. Zhou, H.-T. Chao, M.-Y. Tsai, and C. Chang (2004)
PNAS 101, 11209-11214
 |  Abstract »  |  Full Text »  |  PDF »

The LATS2/KPM Tumor Suppressor Is a Negative Regulator of the Androgen Receptor.

M. Powzaniuk, S. McElwee-Witmer, R. L. Vogel, T. Hayami, S. J. Rutledge, F. Chen, S.-i. Harada, A. Schmidt, G. A. Rodan, L. P. Freedman, et al. (2004)
Mol. Endocrinol. 18, 2011-2023
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Androgen Receptor-mediated Transactivation and Cell Growth by the Glycogen Synthase Kinase 3{beta} in Prostate Cells.

L. Wang, H.-K. Lin, Y.-C. Hu, S. Xie, L. Yang, and C. Chang (2004)
J. Biol. Chem. 279, 32444-32452
 |  Abstract »  |  Full Text »  |  PDF »

Androgens and Bone.

D. Vanderschueren, L. Vandenput, S. Boonen, M. K. Lindberg, R. Bouillon, and C. Ohlsson (2004)
Endocr. Rev. 25, 389-425
 |  Abstract »  |  Full Text »  |  PDF »

Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells.

C. Chang, Y.-T. Chen, S.-D. Yeh, Q. Xu, R.-S. Wang, F. Guillou, H. Lardy, and S. Yeh (2004)
PNAS 101, 6876-6881
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of an Androgen-Responsive Gene Encoding an Aci-Reductone Dioxygenase-Like Protein in the Rat Prostate.

S. Oram, F. Jiang, X. Cai, R. Haleem, Z. Dincer, and Z. Wang (2004)
Endocrinology 145, 1933-1942
 |  Abstract »  |  Full Text »  |  PDF »

Androgen Receptor Coregulators in Prostate Cancer: Mechanisms and Clinical Implications.

M. Rahman, H. Miyamoto, and C. Chang (2004)
Clin. Cancer Res. 10, 2208-2219
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Human Checkpoint Protein hRad9 Functions as a Negative Coregulator To Repress Androgen Receptor Transactivation in Prostate Cancer Cells.

L. Wang, C.-L. Hsu, J. Ni, P.-H. Wang, S. Yeh, P. Keng, and C. Chang (2004)
Mol. Cell. Biol. 24, 2202-2213
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal Growth Factor Increases Coactivation of the Androgen Receptor in Recurrent Prostate Cancer.

C. W. Gregory, X. Fei, L. A. Ponguta, B. He, H. M. Bill, F. S. French, and E. M. Wilson (2004)
J. Biol. Chem. 279, 7119-7130
 |  Abstract »  |  Full Text »  |  PDF »

Ovarian Cancer and Polymorphisms in the Androgen and Progesterone Receptor Genes: A HuGE Review.

F. Modugno (2004)
Am. J. Epidemiol. 159, 319-335
 |  Abstract »  |  Full Text »  |  PDF »

Abnormal Mammary Gland Development and Growth Retardation in Female Mice and MCF7 Breast Cancer Cells Lacking Androgen Receptor.

S. Yeh, Y.-C. Hu, P.-H. Wang, C. Xie, Q. Xu, M.-Y. Tsai, Z. Dong, R.-S. Wang, T.-H. Lee, and C. Chang (2003)
J. Exp. Med. 198, 1899-1908
 |  Abstract »  |  Full Text »  |  PDF »

TR3 Orphan Nuclear Receptor Mediates Apoptosis through Up-regulating E2F1 in Human Prostate Cancer LNCaP Cells.

X. Mu and C. Chang (2003)
J. Biol. Chem. 278, 42840-42845
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Degradation of Androgen Receptor: Mechanism and Clinical Implication.

D. K. Lee and C. Chang (2003)
J. Clin. Endocrinol. Metab. 88, 4043-4054
 |  Abstract »  |  Full Text »  |  PDF »

Specificity of Cyclin D1 for Androgen Receptor Regulation.

C. E. Petre-Draviam, S. L. Cook, C. J. Burd, T. W. Marshall, Y. B. Wetherill, and K. E. Knudsen (2003)
Cancer Res. 63, 4903-4913
 |  Abstract »  |  Full Text »  |  PDF »

The Use of Phage Display Technique for the Isolation of Androgen Receptor Interacting Peptides with (F/W)XXL(F/W) and FXXLY New Signature Motifs.

C.-L. Hsu, Y.-L. Chen, S. Yeh, H.-J. Ting, Y.-C. Hu, H. Lin, X. Wang, and C. Chang (2003)
J. Biol. Chem. 278, 23691-23698
 |  Abstract »  |  Full Text »  |  PDF »

Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action.

G. Castoria, M. Lombardi, M. V. Barone, A. Bilancio, M. Di Domenico, D. Bottero, F. Vitale, A. Migliaccio, and F. Auricchio (2003)
J. Cell Biol. 161, 547-556
 |  Abstract »  |  Full Text »  |  PDF »

APPL Suppresses Androgen Receptor Transactivation via Potentiating Akt Activity.

L. Yang, H.-K. Lin, S. Altuwaijri, S. Xie, L. Wang, and C. Chang (2003)
J. Biol. Chem. 278, 16820-16827
 |  Abstract »  |  Full Text »  |  PDF »

Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells.

M. M. Rahman, H. Miyamoto, H. Lardy, and C. Chang (2003)
PNAS 100, 5124-5129
 |  Abstract »  |  Full Text »  |  PDF »

An Increased CAG Repeat Length in the Androgen Receptor Gene in Azoospermic ICSI Candidates.

L. Mengual, J. Oriola, C. Ascaso, J. L. Ballesca, and R. Oliva (2003)
J Androl 24, 279-284
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Testicular Orphan Receptor-4 (TR4)-associated Protein as Repressor for the Selective Suppression of TR4-mediated Transactivation.

Y. Yang, X. Wang, T. Dong, E. Kim, W.-J. Lin, and C. Chang (2003)
J. Biol. Chem. 278, 7709-7717
 |  Abstract »  |  Full Text »  |  PDF »

RanBPM, a Nuclear Protein That Interacts with and Regulates Transcriptional Activity of Androgen Receptor and Glucocorticoid Receptor.

M. A. Rao, H. Cheng, A. N. Quayle, H. Nishitani, C. C. Nelson, and P. S. Rennie (2002)
J. Biol. Chem. 277, 48020-48027
 |  Abstract »  |  Full Text »  |  PDF »

Differential Modulation of Androgen Receptor-mediated Transactivation by Smad3 and Tumor Suppressor Smad4.

H.-Y. Kang, K.-E. Huang, S. Y. Chang, W.-L. Ma, W.-J. Lin, and C. Chang (2002)
J. Biol. Chem. 277, 43749-43756
 |  Abstract »  |  Full Text »  |  PDF »

Generation and characterization of androgen receptor knockout (ARKO) mice: An in vivo model for the study of androgen functions in selective tissues.

S. Yeh, M.-Y. Tsai, Q. Xu, X.-M. Mu, H. Lardy, K.-E. Huang, H. Lin, S.-D. Yeh, S. Altuwaijri, X. Zhou, et al. (2002)
PNAS 99, 13498-13503
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in the Helix 3 Region of the Androgen Receptor Abrogate ARA70 Promotion of 17beta -Estradiol-induced Androgen Receptor Transactivation.

T. H. Thin, E. Kim, S. Yeh, E. R. Sampson, Y.-T. Chen, L. L. Collins, R. Basavappa, and C. Chang (2002)
J. Biol. Chem. 277, 36499-36508
 |  Abstract »  |  Full Text »  |  PDF »

Phosphatidylinositol 3-Kinase/Akt Stimulates Androgen Pathway through GSK3beta Inhibition and Nuclear beta -Catenin Accumulation.

M. Sharma, W. W. Chuang, and Z. Sun (2002)
J. Biol. Chem. 277, 30935-30941
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Androgen Receptor Transactivation by Pyk2 via Interaction and Phosphorylation of the ARA55 Coregulator.

X. Wang, Y. Yang, X. Guo, E. R. Sampson, C.-L. Hsu, M.-Y. Tsai, S. Yeh, G. Wu, Y. Guo, and C. Chang (2002)
J. Biol. Chem. 277, 15426-15431
 |  Abstract »  |  Full Text »  |  PDF »

Androgen Receptor (AR) Coregulators: An Overview.

C. A. Heinlein and C. Chang (2002)
Endocr. Rev. 23, 175-200
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of Ligand-Dependent Changes in AR Structure Using Peptide Probes.

C.-Y. Chang and D. P. McDonnell (2002)
Mol. Endocrinol. 16, 647-660
 |  Abstract »  |  Full Text »  |  PDF »

A Dominant-negative Mutant of Androgen Receptor Coregulator ARA54 Inhibits Androgen Receptor-mediated Prostate Cancer Growth.

H. Miyamoto, M. Rahman, H. Takatera, H.-Y. Kang, S. Yeh, H.-C. Chang, K. Nishimura, N. Fujimoto, and C. Chang (2002)
J. Biol. Chem. 277, 4609-4617
 |  Abstract »  |  Full Text »  |  PDF »

5'TG3' Interacting Factor Interacts with Sin3A and Represses AR-Mediated Transcription.

M. Sharma and Z. Sun (2001)
Mol. Endocrinol. 15, 1918-1928
 |  Abstract »  |  Full Text »  |  PDF »

p53 Represses Androgen-induced Transactivation of Prostate-specific Antigen by Disrupting hAR Amino- to Carboxyl-terminal Interaction.

J. L. Shenk, C. J. Fisher, S.-Y. Chen, X.-F. Zhou, K. Tillman, and L. Shemshedini (2001)
J. Biol. Chem. 276, 38472-38479
 |  Abstract »  |  Full Text »  |  PDF »

The Endocrinology of Prostate Cancer.

M. E. Taplin and S.-M. Ho (2001)
J. Clin. Endocrinol. Metab. 86, 3467-3477
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Phenotypic Variation in a Family with Partial Androgen Insensitivity Syndrome Explained by Differences in 5{{alpha}} Dihydrotestosterone Availability.

A. L. M. Boehmer, A. O. Brinkmann, R. M. Nijman, M. C. T. Verleun-Mooijman, P. de Ruiter, M. F. Niermeijer, and S. L. S. Drop (2001)
J. Clin. Endocrinol. Metab. 86, 1240-1246
 |  Abstract »  |  Full Text »

SMAD3 Represses Androgen Receptor-mediated Transcription.

S. A. Hayes, M. Zarnegar, M. Sharma, F. Yang, D. M. Peehl, P. t. Dijke, and Z. Sun (2001)
Cancer Res. 61, 2112-2118
 |  Abstract »  |  Full Text »

Multiple Actions of Steroid Hormones---A Focus on Rapid, Nongenomic Effects.

E. Falkenstein, H.-C. Tillmann, M. Christ, M. Feuring, and M. Wehling (2000)
Pharmacol. Rev. 52, 513-556
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression of Estrogen Receptor-{alpha} and -{beta} and Androgen Receptor in the Ovaries of Marmosets and Humans.

P. T.K. Saunders, M. R. Millar, K. Williams, S. Macpherson, D. Harkiss, R. A. Anderson, B. Orr, N. P. Groome, G. Scobie, and H. M. Fraser (2000)
Biol Reprod 63, 1098-1105
 |  Abstract »  |  Full Text »

Alteration of Follicle-Stimulating Hormone and Testosterone Regulation of Messenger Ribonucleic Acid for Sertoli Cell Proteins in the Rat During the Acute Phase of Spinal Cord Injury.

J. E. Ottenweller, M.-T. Li, W. Giglio, R. Anesetti, L. M. Pogach, and H. F.S. Huang (2000)
Biol Reprod 63, 730-735
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Characterization of Conserved T- and B-Cell Epitopes in Plasmodium falciparum Major Merozoite Surface Protein 1.

M. Parra, G. Hui, A. H. Johnson, J. A. Berzofsky, T. Roberts, I. A. Quakyi, and D. W. Taylor (2000)
Infect. Immun. 68, 2685-2691
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Isolation and Characterization of Peroxisome Proliferator-activated Receptor (PPAR) Interacting Protein (PRIP) as a Coactivator for PPAR.

Y. Zhu, L. Kan, C. Qi, Y. S. Kanwar, A. V. Yeldandi, M. S. Rao, and J. K. Reddy (2000)
J. Biol. Chem. 275, 13510-13516
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The Role of the CAG Repeat Polymorphism in the Androgen Receptor Gene and of Skewed X-Chromosome Inactivation, in the Pathogenesis of Hirsutism.

R. M. Calvo, M. Asunción, J. Sancho, J. L. San Millán, and H. F. Escobar-Morreale (2000)
J. Clin. Endocrinol. Metab. 85, 1735-1740
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From Androgen Receptor to the General Transcription Factor TFIIH. IDENTIFICATION OF cdk ACTIVATING KINASE (CAK) AS AN ANDROGEN RECEPTOR NH2-TERMINAL ASSOCIATED COACTIVATOR.

D. K. Lee, H. O. Duan, and C. Chang (2000)
J. Biol. Chem. 275, 9308-9313
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Protein Inhibitor of Activated STAT-1 (Signal Transducer and Activator of Transcription-1) Is a Nuclear Receptor Coregulator Expressed in Human Testis.

J.-a. Tan, S. H. Hall, K. G. Hamil, G. Grossman, P. Petrusz, J. Liao, K. Shuai, and F. S. French (2000)
Mol. Endocrinol. 14, 14-26
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Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: A unique signaling pathway in the steroid receptor superfamily.

Y.-F. Lee, C.-R. Shyr, T. H. Thin, W.-J. Lin, and C. Chang (1999)
PNAS 96, 14724-14729
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Identification and Cloning of a Novel Androgen-Responsive Gene, Uridine Diphosphoglucose Dehydrogenase, in Human Breast Cancer Cells.

J. Lapointe and C. Labrie (1999)
Endocrinology 140, 4486-4493
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Cooperative Assembly of Androgen Receptor into a Nucleoprotein Complex That Regulates the Prostate-specific Antigen Enhancer.

W. Huang, Y. Shostak, P. Tarr, C. Sawyers, and M. Carey (1999)
J. Biol. Chem. 274, 25756-25768
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Androgen Specificity of a Response Unit Upstream of the Human Secretory Component Gene Is Mediated by Differential Receptor Binding to an Essential Androgen Response Element.

G. Verrijdt, E. Schoenmakers, P. Alen, A. Haelens, B. Peeters, W. Rombauts, and F. Claessens (1999)
Mol. Endocrinol. 13, 1558-1570
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Isolation and Characterization of ARA160 as the First Androgen Receptor N-terminal-associated Coactivator in Human Prostate Cells.

P.-W. Hsiao and C. Chang (1999)
J. Biol. Chem. 274, 22373-22379
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Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-{kappa}B and Steroid Receptor-Signaling Pathways.

L. I. McKay and J. A. Cidlowski (1999)
Endocr. Rev. 20, 435-459
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The Linkage of Kennedy's Neuron Disease to ARA24, the First Identified Androgen Receptor Polyglutamine Region-associated Coactivator.

P.-W. Hsiao, D.-L. Lin, R. Nakao, and C. Chang (1999)
J. Biol. Chem. 274, 20229-20234
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Homologous Androgen Receptor Up-Regulation in Osteoblastic Cells May Be Associated with Enhanced Functional Androgen Responsiveness.

K. Wiren, E. Keenan, X. Zhang, B. Ramsey, and E. Orwoll (1999)
Endocrinology 140, 3114-3124
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From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells.

S. Yeh, H.-K. Lin, H.-Y. Kang, T. H. Thin, M.-F. Lin, and C. Chang (1999)
PNAS 96, 5458-5463
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A Novel Mutation in the CAG Triplet Region of Exon 1 of Androgen Receptor Gene Causes Complete Androgen Insensitivity Syndrome in a Large Kindred.

Y.-S. Zhu, L.-Q. Cai, J. J. Cordero, W. J. Canovatchel, M. D. Katz, and J. Imperato-McGinley (1999)
J. Clin. Endocrinol. Metab. 84, 1590-1594
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Cloning and Characterization of Human Prostate Coactivator ARA54, a Novel Protein That Associates with the Androgen Receptor.

H.-Y. Kang, S. Yeh, N. Fujimoto, and C. Chang (1999)
J. Biol. Chem. 274, 8570-8576
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The Detrimental Effects of Spinal Cord Injury on Spermatogenesis in the Rat Is Partially Reversed by Testosterone, but Enhanced by Follicle- Stimulating Hormone.

H. F. S. Huang, M.-T. Li, W. Giglio, R. Anesetti, J. E. Ottenweller, and L. M. Pogach (1999)
Endocrinology 140, 1349-1355
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Androgen receptor gene mutations in 46,XY females with germ cell tumours.

C.-P. Chen, S.-R. Chern, T.-Y. Wang, W. Wang, K.-L. Wang, and C.-J. Jeng (1999)
Hum. Reprod. 14, 664-670
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Effects of Spinal Cord Injury on Spermatogenesis and the Expression of Messenger Ribonucleic Acid for Sertoli Cell Proteins in Rat Sertoli Cell-Enriched Testes.

H. F.S. Huang, M.-t. Li, R. Anesetti, W. Giglio, J. E. Ottenweller, and L. M. Pogach (1999)
Biol Reprod 60, 635-641
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Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells.

H. Miyamoto, S. Yeh, G. Wilding, and C. Chang (1998)
PNAS 95, 7379-7384
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Androgen receptors in human preadipocytes and adipocytes: regional specificities and regulation by sex steroids.

M. N. Dieudonne, R. Pecquery, A. Boumediene, M. C. Leneveu, and Y. Giudicelli (1998)
Am J Physiol Cell Physiol 274, C1645-C1652
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From estrogen to androgen receptor: A new pathway for sex hormones in prostate.

S. Yeh, H. Miyamoto, H. Shima, and C. Chang (1998)
PNAS 95, 5527-5532
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Functional Activities of the A and B Forms of the Human Androgen Receptor in Response to Androgen Receptor Agonists and Antagonists.

T. Gao and M. J. McPhaul (1998)
Mol. Endocrinol. 12, 654-663
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Regulation of Sexual Dimorphism in Mammals.

C. M. HAQQ and P. K. DONAHOE (1998)
Physiol Rev 78, 1-33
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