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Science 13 November 1987: Vol. 238. no. 4829, pp. 933 - 937 DOI: 10.1126/science.3672135
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Articles
Science, Vol 238, Issue 4829, 933-937
Copyright © 1987 by American Association for the Advancement of Science
Structurally distinct, stage-specific ribosomes occur in Plasmodium
JH Gunderson,
ML Sogin,
G Wollett,
M Hollingdale,
VF de la Cruz,
AP Waters,
and
TF McCutchan
National Jewish Center for Immunology and Respiratory Medicine, Denver, CO 80206.
Two structurally distinct nuclear genes code for cytoplasmic small subunit ribosomal RNA's in the parasite Plasmodium berghei. Stable transcripts from one of the ribosomal RNA genes are found almost exclusively in those stages of the life cycle that develop in the mosquito. When the parasite infects the mammalian host, transcripts from the second gene become the predominant small subunit ribosomal RNA species.
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