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Science 31 July 1987:
Vol. 237. no. 4814, pp. 535 - 537
DOI: 10.1126/science.2885921
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Articles

Science, Vol 237, Issue 4814, 535-537
Copyright © 1987 by American Association for the Advancement of Science

articles

Full-wave rectification from a mixed electrical-chemical synapse

K Graubard and DK Hartline

Electrical and chemical synapses usually reinforce one another, but the pyloric late-to-lateral pyloric (PL-to-LP) neuronal connections in lobster stomatogastric ganglia create an inverted U-shaped transfer function between the two neurons: regardless of whether the PL membrane voltage swings positive or negative, the postsynaptic LP voltage will go negative. When the presynaptic cell voltage goes negative, the effect on the LP voltage is due to electrical coupling. During positive presynaptic voltages, the strong contribution of graded chemical inhibition from the PL to the LP neuron overrides the positive electrical coupling to produce net negativity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Short-Term Dynamics of a Mixed Chemical and Electrical Synapse in a Rhythmic Network.
A. Mamiya, Y. Manor, and F. Nadim (2003)
J. Neurosci. 23, 9557-9564
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Coactivation of Motoneurons Regulated by a Network Combining Electrical and Chemical Synapses.
L. Rela and L. Szczupak (2003)
J. Neurosci. 23, 682-692
   Abstract »    Full Text »    PDF »
Electrical Coupling Can Prevent Expression of Adult-Like Properties in an Embryonic Neural Circuit.
T. Bem, Y. Le Feuvre, J. Simmers, and P. Meyrand (2002)
J Neurophysiol 87, 538-547
   Abstract »    Full Text »    PDF »
Dynamic Control of Irregular Bursting in an Identified Neuron of an Oscillatory Circuit.
R. C. Elson, R. Huerta, H. D. I. Abarbanel, M. I. Rabinovich, and A. I. Selverston (1999)
J Neurophysiol 82, 115-122
   Abstract »    Full Text »    PDF »


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