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Science 5 June 1987:
Vol. 236. no. 4806, pp. 1223 - 1229
DOI: 10.1126/science.3296189
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Articles

Science, Vol 236, Issue 4806, 1223-1229
Copyright © 1987 by American Association for the Advancement of Science

articles

Disease diagnosis by recombinant DNA methods

CT Caskey

Recombinant DNA procedures have now been applied to the problem of the identification of molecular defects in man that account for heritable diseases, somatic mutations associated with neoplasia, and acquired infectious disease. Thus recombinant DNA technology has rapidly expanded our ability to diagnose disease. Substantial advances in the simplification of procedures for diagnostic purposes have been made, and the informed physician has gained in diagnostic accuracy as a consequence of these developments. The wide application of recombinant DNA diagnostics will depend on simplicity, speed of results, and cost containment.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Molecular genetics: applications to the clinical neurosciences.
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