Science 15 May 1987: Vol. 236. no. 4803, pp. 806 - 812 DOI: 10.1126/science.3033825

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Articles

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome.

D. G. Gibson, G. A. Benders, C. Andrews-Pfannkoch, E. A. Denisova, H. Baden-Tillson, J. Zaveri, T. B. Stockwell, A. Brownley, D. W. Thomas, M. A. Algire, et al. (2008)
Science 319, 1215-1220
 |  Abstract »  |  Full Text »  |  PDF »

Isolation and Characterization of Saccharomyces cerevisiae Mutants Defective in Chromosome Transmission in an Undergraduate Genetics Research Course.

H. M. Sleister (2007)
Genetics 177, 677-688
 |  Abstract »  |  Full Text »  |  PDF »

An Artificially Constructed De Novo Human Chromosome Behaves Almost Identically to Its Natural Counterpart during Metaphase and Anaphase in Living Cells..

T. Tsuduki, M. Nakano, N. Yasuoka, S. Yamazaki, T. Okada, Y. Okamoto, and H. Masumoto (2006)
Mol. Cell. Biol. 26, 7682-7695
 |  Abstract »  |  Full Text »  |  PDF »

Iterative in vivo assembly of large and complex transgenes by combining the activities of {varphi}C31 integrase and Cre recombinase.

F. Dafhnis-Calas, Z. Xu, S. Haines, S. K. Malla, M. C. M. Smith, and W. R. A. Brown (2005)
Nucleic Acids Res. 33, e189
 |  Abstract »  |  Full Text »  |  PDF »

From The Cover: Combining two genomes in one cell: Stable cloning of the Synechocystis PCC6803 genome in the Bacillus subtilis 168 genome.

M. Itaya, K. Tsuge, M. Koizumi, and K. Fujita (2005)
PNAS 102, 15971-15976
 |  Abstract »  |  Full Text »  |  PDF »

Gene CATCHR--Gene Cloning And Tagging for Caenorhabditis elegans using yeast Homologous Recombination: a novel approach for the analysis of gene expression.

H. E. Sassi, S. Renihan, A. M. Spence, and R. L. Cooperstock (2005)
Nucleic Acids Res. 33, e163
 |  Abstract »  |  Full Text »  |  PDF »

A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy.

M. Lindenbaum, E. Perkins, E. Csonka, E. Fleming, L. Garcia, A. Greene, L. Gung, G. Hadlaczky, E. Lee, J. Leung, et al. (2004)
Nucleic Acids Res. 32, e172
 |  Abstract »  |  Full Text »  |  PDF »

Efficient Generation of Transgenic Mice with Intact Yeast Artificial Chromosomes by Intracytoplasmic Sperm Injection.

P. N. Moreira, P. Giraldo, P. Cozar, J. Pozueta, A. Jimenez, L. Montoliu, and A. Gutierrez-Adan (2004)
Biol Reprod 71, 1943-1947
 |  Abstract »  |  Full Text »  |  PDF »

Human chromosome 7 circa 2004: a model for structural and functional studies of the human genome.

S. W. Scherer and E. D. Green (2004)
Hum. Mol. Genet. 13, R303-R313
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic mice as a model to study the regulation of human transferrin expression in Sertoli cells.

C. Lecureuil, M.C. Saleh, I. Fontaine, B. Baron, M.M. Zakin, and F. Guillou (2004)
Hum. Reprod. 19, 1300-1307
 |  Abstract »  |  Full Text »  |  PDF »

Anchoring 9,371 Maize Expressed Sequence Tagged Unigenes to the Bacterial Artificial Chromosome Contig Map by Two-Dimensional Overgo Hybridization.

J. Gardiner, S. Schroeder, M. L. Polacco, H. Sanchez-Villeda, Z. Fang, M. Morgante, T. Landewe, K. Fengler, F. Useche, M. Hanafey, et al. (2004)
Plant Physiology 134, 1317-1326
 |  Abstract »  |  Full Text »  |  PDF »

Epigenetic assembly of centromeric chromatin at ectopic {alpha}-satellite sites on human chromosomes.

M. Nakano, Y. Okamoto, J.-i. Ohzeki, and H. Masumoto (2003)
J. Cell Sci. 116, 4021-4034
 |  Abstract »  |  Full Text »  |  PDF »

Stable Positional Cloning of Long Continuous DNA in the Bacillus subtilis Genome Vector.

M. Itaya, K. Fujita, M. Ikeuchi, M. Koizumi, and K. Tsuge (2003)
J. Biochem. 134, 513-519
 |  Abstract »  |  Full Text »  |  PDF »

Conversion of sub-megasized DNA to desired structures using a novel Bacillus subtilis genome vector.

S. Kaneko, K. Tsuge, T. Takeuchi, and M. Itaya (2003)
Nucleic Acids Res. 31, e112
 |  Abstract »  |  Full Text »  |  PDF »

Chromosome integrity in Saccharomyces cerevisiae: the interplay of DNA replication initiation factors, elongation factors, and origins.

D. Huang and D. Koshland (2003)
Genes & Dev. 17, 1741-1754
 |  Abstract »  |  Full Text »  |  PDF »

A Sensitive and Inexpensive Yeast Bioassay for the Mycotoxin Zearalenone and Other Compounds with Estrogenic Activity.

R. Mitterbauer, H. Weindorfer, N. Safaie, R. Krska, M. Lemmens, P. Ruckenbauer, K. Kuchler, and G. Adam (2003)
Appl. Envir. Microbiol. 69, 805-811
 |  Abstract »  |  Full Text »  |  PDF »

The Finished Genome Sequence of Homo sapiens.

J. ROGERS (2003)
Cold Spring Harb Symp Quant Biol 68, 1-12
 |  Abstract »  |  PDF »

A Three-Megabase Yeast Artificial Chromosome Contig Spanning the C57BL Mouse Igh Locus.

C. Chevillard, J. Ozaki, C. D. Herring, and R. Riblet (2002)
J. Immunol. 168, 5659-5666
 |  Abstract »  |  Full Text »  |  PDF »

Stable Replication of Papillomavirus Genomes in Saccharomyces cerevisiae.

P. C. Angeletti, K. Kim, F. J. Fernandes, and P. F. Lambert (2002)
J. Virol. 76, 3350-3358
 |  Abstract »  |  Full Text »  |  PDF »

Saccharomyces cerevisiae URH1 (Encoding Uridine-Cytidine N-Ribohydrolase): Functional Complementation by a Nucleoside Hydrolase from a Protozoan Parasite and by a Mammalian Uridine Phosphorylase.

R. Mitterbauer, T. Karl, and G. Adam (2002)
Appl. Envir. Microbiol. 68, 1336-1343
 |  Abstract »  |  Full Text »  |  PDF »

A genetic system for direct selection of gene-positive clones during recombinational cloning in yeast.

V. Noskov, N. Kouprina, S.-H. Leem, M. Koriabine, J. C. Barrett, and V. Larionov (2002)
Nucleic Acids Res. 30, e8
 |  Abstract »  |  Full Text »  |  PDF »

Yeast telomerase appears to frequently copy the entire template in vivo.

A. Ray and K. W. Runge (2001)
Nucleic Acids Res. 29, 2382-2394
 |  Abstract »  |  Full Text »  |  PDF »

A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli.

M. D. Lalioti and J. K. Heath (2001)
Nucleic Acids Res. 29, e14
 |  Abstract »  |  Full Text »  |  PDF »

Mice with an Increased Glucocorticoid Receptor Gene Dosage Show Enhanced Resistance to Stress and Endotoxic Shock.

H. M. Reichardt, T. Umland, A. Bauer, O. Kretz, and G. Schütz (2000)
Mol. Cell. Biol. 20, 9009-9017
 |  Abstract »  |  Full Text »

TRF1 is a critical trans-acting factor required for de novo telomere formation in human cells.

J. Okabe, A. Eguchi, A. Masago, T. Hayakawa, and M. Nakanishi (2000)
Hum. Mol. Genet. 9, 2639-2650
 |  Abstract »  |  Full Text »  |  PDF »

Decoding the human genome sequence.

D. R. Bentley (2000)
Hum. Mol. Genet. 9, 2353-2358
 |  Abstract »  |  Full Text »  |  PDF »

Recovery and potential utility of YACs as circular YACs/BACs.

M. Cocchia, N. Kouprina, S.-J. Kim, V. Larionov, D. Schlessinger, and R. Nagaraja (2000)
Nucleic Acids Res. 28, e81
 |  Abstract »  |  Full Text »  |  PDF »

A Cre-lox recombination system for the targeted integration of circular yeast artificial chromosomes into embryonic stem cells.

L. M. Call, C. S. Moore, G. Stetten, and J. D. Gearhart (2000)
Hum. Mol. Genet. 9, 1745-1751
 |  Abstract »  |  Full Text »  |  PDF »

Mammalian artificial chromosome formation from circular alphoid input DNA does not require telomere repeats.

T. A. Ebersole, A. Ross, E. Clark, N. McGill, D. Schindelhauer, H. Cooke, and B. Grimes (2000)
Hum. Mol. Genet. 9, 1623-1631
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of 5S rDNA Arrays in Arabidopsis thaliana: Physical Mapping and Chromosome-Specific Polymorphisms.

C. Cloix, S. Tutois, O. Mathieu, C. Cuvillier, M.C. Espagnol, G. Picard, and S. Tourmente (2000)
Genome Res. 10, 679-690
 |  Abstract »  |  Full Text »

Construction of a BAC Contig Map of Chromosome 16q by Two-Dimensional Overgo Hybridization.

C. S. Han, R. D. Sutherland, P. B. Jewett, M. L. Campbell, L. J. Meincke, J. G. Tesmer, M. O. Mundt, J. J. Fawcett, U.-J. Kim, L. L. Deaven, et al. (2000)
Genome Res. 10, 714-721
 |  Abstract »  |  Full Text »

Rational design of landmark probes for quantitative DNA fiber mapping (QDFM).

H. B. Hsieh, M. Wang, R. A. Lersch, U.-J. Kim, and H.-U. G. Weier (2000)
Nucleic Acids Res. 28, e30-e
 |  Abstract »  |  Full Text »  |  PDF »

Developmentally distinct effects on human {varepsilon}-, {gamma}- and {delta}-globin levels caused by the absence or altered position of the human {beta}-globin gene in YAC transgenic mice.

R. Bauchwitz and F. Costantini (2000)
Hum. Mol. Genet. 9, 561-574
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the human CFTR gene from episomal oriP-EBNA1-YACs in mouse cells.

D. Huertas, S. Howe, A. McGuigan, and C. Huxley (2000)
Hum. Mol. Genet. 9, 617-629
 |  Abstract »  |  Full Text »  |  PDF »

Induction and Characterization of Ph1 Wheat Mutants.

M. A. Roberts, S. M. Reader, C. Dalgliesh, T. E. Miller, T. N. Foote, L. J. Fish, J. W. Snape, and G. Moore (1999)
Genetics 153, 1909-1918
 |  Abstract »  |  Full Text »

The Mla (Powdery Mildew) Resistance Cluster Is Associated With Three NBS-LRR Gene Families and Suppressed Recombination Within a 240-kb DNA Interval on Chromosome 5S (1HS) of Barley.

F. Wei, K. Gobelman-Werner, S. M. Morroll, J. Kurth, L. Mao, R. Wing, D. Leister, P. Schulze-Lefert, and R. P. Wise (1999)
Genetics 153, 1929-1948
 |  Abstract »  |  Full Text »

Molecular and Epidemiological Characterization of Vaginal Saccharomyces cerevisiae Isolates.

B. Posteraro, M. Sanguinetti, G. D'Amore, L. Masucci, G. Morace, and G. Fadda (1999)
J. Clin. Microbiol. 37, 2230-2235
 |  Abstract »  |  Full Text »

Active Role of a Human Genomic Insert in Replication of a Yeast Artificial Chromosome.

A. J. van Brabant, W. L. Fangman, and B. J. Brewer (1999)
Mol. Cell. Biol. 19, 4231-4240
 |  Abstract »  |  Full Text »  |  PDF »

Complementation of plant mutants with large genomic DNA fragments by a transformation-competent artificial chromosome vector accelerates positional cloning.

Y.-G. Liu, Y. Shirano, H. Fukaki, Y. Yanai, M. Tasaka, S. Tabata, and D. Shibata (1999)
PNAS 96, 6535-6540
 |  Abstract »  |  Full Text »  |  PDF »

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.

K. A. Henning, E. A. Novotny, S. T. Compton, X.-Y. Guan, P. P. Liu, and M. A. Ashlock (1999)
PNAS 96, 592-597
 |  Abstract »  |  Full Text »  |  PDF »

Mapping ESTs by Fiber-FISH.

N. Horelli-Kuitunen, J. Aaltonen, M.-L. Yaspo, M. Eeva, M. Wessman, L. Peltonen, and A. Palotie (1999)
Genome Res. 9, 62-71
 |  Abstract »  |  Full Text »

Genome Sequence of the Nematode C. elegans: A Platform for Investigating Biology.

The C. elegans Sequencing Consortium (1998)
Science 282, 2012-2018
 |  Abstract »  |  Full Text »

Construction and validation of yeast artificial chromosome contig maps by RecA-assisted restriction endonuclease cleavage.

P. Lauer, S. S. Schneider, and A. Gnirke (1998)
PNAS 95, 11318-11323
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Stage-Specific cis-Active Transcriptional Mechanisms Control Expression of T Cell Coreceptor CD8{alpha} at Double- and Single-Positive Stages of Thymic Development.

X.-L. Zhang, R. Seong, R. Piracha, M. Larijani, M. Heeney, J. R. Parnes, and J. W. Chamberlain (1998)
J. Immunol. 161, 2254-2266
 |  Abstract »  |  Full Text »  |  PDF »

Rescue of Targeted Regions of Mammalian Chromosomes by in Vivo Recombination in Yeast.

N. Kouprina, K. Kawamoto, J. C. Barrett, V. Larionov, and M. Koi (1998)
Genome Res. 8, 666-672
 |  Abstract »  |  Full Text »

Vector-Hexamer PCR Isolation of All Insert Ends from a YAC Contig of the Mouse Igh Locus.

C. D. Herring, C. Chevillard, S. L. Johnston, P. J. Wettstein, and R. Riblet (1998)
Genome Res. 8, 673-681
 |  Abstract »  |  Full Text »

Dissection of the Fusarium I2 Gene Cluster in Tomato Reveals Six Homologs and One Active Gene Copy.

G. Simons, J. Groenendijk, J. Wijbrandi, M. Reijans, J. Groenen, P. Diergaarde, T. Van der Lee, M. Bleeker, J. Onstenk, M. de Both, et al. (1998)
PLANT CELL 10, 1055-1068
 |  Abstract »  |  Full Text »

Screening for overlapping bacterial artificial chromosome clones by PCR analysis with an arbitrary primer.

J. Xu, D. Yang, J. Domingo, J. Ni, and N. Huang (1998)
PNAS 95, 5661-5666
 |  Abstract »  |  Full Text »  |  PDF »

Modification of bacterial artificial chromosomes through Chi-stimulated homologous recombination and its application in zebrafish transgenesis.

J. R. Jessen, A. Meng, R. J. McFarlane, B. H. Paw, L. I. Zon, G. R. Smith, and S. Lin (1998)
PNAS 95, 5121-5126
 |  Abstract »  |  Full Text »  |  PDF »

Modification of Bacterial Artificial Chromosome Clones Using Cre Recombinase: Introduction of Selectable Markers for Expression in Eukaryotic Cells.

S. Y. Kim, S. K. Horrigan, J. L. Altenhofen, Z. H. Arbieva, R. Hoffman, and C. A. Westbrook (1998)
Genome Res. 8, 404-412
 |  Abstract »  |  Full Text »

A Physical Map of Human Chromosome 7: An Integrated YAC Contig Map with Average STS Spacing of 79 kb.

G. G. Bouffard, J. R. Idol, V. V. Braden, L. M. Iyer, A. F. Cunningham, L. A. Weintraub, J. W. Touchman, R. M. Mohr-Tidwell, D. C. Peluso, R. S. Fulton, et al. (1997)
Genome Res. 7, 673-692
 |  Abstract »  |  Full Text »  |  PDF »

X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content..

R Nagaraja, S MacMillan, J Kere, C Jones, S Griffin, M Schmatz, J Terrell, M Shomaker, C Jermak, C Hott, et al. (1997)
Genome Res. 7, 210-222
 |  Abstract »  |  PDF »

Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family..

C A Wise, G A Clines, H Massa, B J Trask, and M Lovett (1997)
Genome Res. 7, 10-16
 |  Abstract »  |  PDF »

Highly selective isolation of human DNAs from rodent-human hybrid cells as circular yeast artificial chromosomes by transformation-associated recombination cloning.

V. Larionov, N. Kouprina, J. Graves, and M. A. Resnick (1996)
PNAS 93, 13925-13930
 |  Abstract »  |  Full Text »  |  PDF »

An integrated YAC map of the human X chromosome..

H Roest Crollius, M T Ross, A Grigoriev, C J Knights, E Holloway, J Misfud, K Li, M Playford, S G Gregory, S J Humphray, et al. (1996)
Genome Res. 6, 943-955
 |  Abstract »  |  PDF »

Bacterial artificial chromosome cloning and mapping of a 630-kb human extrachromosomal structure..

M Wang, S Shouse, B Lipes, U J Kim, H Shizuya, and E Lai (1996)
Genome Res. 6, 612-619
 |  Abstract »  |  PDF »

A P1-based physical map of the Drosophila euchromatic genome..

W Kimmerly, K Stultz, S Lewis, K Lewis, V Lustre, R Romero, J Benke, D Sun, G Shirley, C Martin, et al. (1996)
Genome Res. 6, 414-430
 |  Abstract »  |  PDF »

A new approach using multiplex long accurate PCR and yeast artificial chromosomes for bacterial chromosome mapping and sequencing..

A Sorokin, A Lapidus, V Capuano, N Galleron, P Pujic, and S D Ehrlich (1996)
Genome Res. 6, 448-453
 |  Abstract »  |  PDF »

Mapping the RP10 locus for autosomal dominant retinitis pigmentosa on 7q: refined genetic positioning and localization within a well-defined YAC contig..

R E McGuire, S A Jordan, V V Braden, G G Bouffard, P Humphries, E D Green, and S P Daiger (1996)
Genome Res. 6, 255-266
 |  Abstract »  |  PDF »

Toward the construction of integrated physical and genetic maps of the mouse genome using interspersed repetitive sequence PCR (IRS-PCR) genomics..

K W Hunter, L Riba, L Schalkwyk, M Clark, S Resenchuk, A Beeghly, J Su, F Tinkov, P Lee, E Ramu, et al. (1996)
Genome Res. 6, 290-299
 |  Abstract »  |  PDF »

Positional candidate genes for congenital chloride diarrhea suggested by high-resolution physical mapping in chromosome region 7q31..

P Hoglund, S Haila, S W Scherer, L C Tsui, E D Green, J Weissenbach, C Holmberg, A de la Chapelle, and J Kere (1996)
Genome Res. 6, 202-210
 |  Abstract »  |  PDF »

Molecular dissection of quantitative traits: progress and prospects..

A H Paterson (1995)
Genome Res. 5, 321-333
 |  Abstract »  |  PDF »

Refined localization of the cerebral cavernous malformation gene (CCM1) to a 4-cM interval of chromosome 7q contained in a well-defined YAC contig..

E W Johnson, L M Iyer, S S Rich, H T Orr, A Gil-Nagel, J H Kurth, J M Zabramski, D A Marchuk, J Weissenbach, and C L Clericuzio (1995)
Genome Res. 5, 368-380
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Molecular cloning and RARE cleavage mapping of human 2p, 6q, 8q, 12q, and 18q telomeres..

R A Macina, K Morii, X L Hu, D G Negorev, C Spais, L A Ruthig, and H C Riethman (1995)
Genome Res. 5, 225-232
 |  Abstract »  |  PDF »

A YAC-based contig of 1.5 Mb spanning the human multidrug resistance gene region and delineating the amplification unit in three human multidrug-resistant cell lines..

K Torigoe, S Sato, H Kusaba, K Kohno, M Kuwano, K Okumura, E D Green, L C Tsui, S W Scherer, and D Schlessinger (1995)
Genome Res. 5, 233-244
 |  Abstract »  |  PDF »

ILR1, an amidohydrolase that releases active indole-3-acetic acid from conjugates.

B Bartel and G. Fink (1995)
Science 268, 1745-1748
 |  Abstract »  |  PDF »

Assessment of colinearity between large cloned DNA fragments and genomic DNA..

P Verhasselt and G Volckaert (1994)
Genome Res. 4, 129-132
 |  PDF »

Forward and reverse genetic approaches to behavior in the mouse.

J. Takahashi, L. Pinto, and M. Vitaterna (1994)
Science 264, 1724-1733
 |  Abstract »  |  PDF »

Isolating vector-insert junctions from yeast artificial chromosomes..

G A Silverman (1993)
Genome Res. 3, 141-150
 |  PDF »

Cloning of Tumor Suppressor Genes Involved in Solid Tumor Development.

D. I. Smith and M. del Mar Alonso (1993)
Arch Otolaryngol Head Neck Surg 119, 1210-1216
 |  Abstract »  |  PDF »

Ordered restriction maps of Saccharomyces cerevisiae chromosomes constructed by optical mapping.

D. Schwartz, X Li, L. Hernandez, S. Ramnarain, E. Huff, and Y. Wang (1993)
Science 262, 110-114
 |  Abstract »  |  PDF »

Molecular Medicine: A Spin-off From the Helix.

C. T. Caskey (1993)
JAMA 269, 1986-1992
 |  Abstract »  |  PDF »

Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(I) collagen locus.

W. Strauss, J Dausman, C Beard, C Johnson, J. Lawrence, and R Jaenisch (1993)
Science 259, 1904-1907
 |  Abstract »  |  PDF »

The Drosophila melanogaster dodecasatellite sequence is closely linked to the centromere and can form connections between sister chromatids during mitosis.

M Carmena, J. Abad, A Villasante, and C Gonzalez (1993)
J. Cell Sci. 105, 41-50
 |  Abstract »  |  PDF »

Generation of Transgenic Mice with Yeast Artificial Chromosomes.

L. Montoliu, A. Schedl, G. Kelsey, P. Lichter, Z. Larin, H. Lehrach, and G. Schutz (1993)
Cold Spring Harb Symp Quant Biol 58, 55-62
 |  Abstract »  |  PDF »

The Genome of the Nematode Caenorhabditis elegans.

R. Waterston, R. Ainscough, K. Anderson, M. Berks, D. Blair, M. Connell, J. Cooper, A. Coulson, M. Craxton, S. Dear, et al. (1993)
Cold Spring Harb Symp Quant Biol 58, 367-376
 |  Abstract »  |  PDF »

The human Y chromosome: overlapping DNA clones spanning the euchromatic region.

S Foote, D Vollrath, A Hilton, and D. Page (1992)
Science 258, 60-66
 |  Abstract »  |  PDF »

Genome analysis and the human X chromosome.

J. Mandel, A. Monaco, D. Nelson, D Schlessinger, and H Willard (1992)
Science 258, 103-109
 |  Abstract »  |  PDF »

Sequence-tagged site (STS) content mapping of human chromosomes: theoretical considerations and early experiences..

E D Green and P Green (1991)
Genome Res. 1, 77-90
 |  Abstract »  |  PDF »

Capture PCR: efficient amplification of DNA fragments adjacent to a known sequence in human and YAC DNA..

M Lagerstrom, J Parik, H Malmgren, J Stewart, U Pettersson, and U Landegren (1991)
Genome Res. 1, 111-119
 |  Abstract »  |  PDF »

Toward cloning and mapping the genome of Drosophila.

J Merriam, M Ashburner, D. Hartl, and F. Kafatos (1991)
Science 254, 221-225
 |  Abstract »  |  PDF »

The Human Genome Project: Prospects and Implications for Clinical Medicine.

E. D. Green and R. H. Waterston (1991)
JAMA 266, 1966-1975
 |  Abstract »  |  PDF »

Large-scale and automated DNA sequence determination.

T Hunkapiller, R. Kaiser, B. Koop, and L Hood (1991)
Science 254, 59-67
 |  Abstract »  |  PDF »

Isolation of sequences that span the fragile X and identification of a fragile X-related CpG island.

D Heitz, F Rousseau, D Devys, S Saccone, H Abderrahim, D Le Paslier, D Cohen, A Vincent, D Toniolo, G Della Valle, et al. (1991)
Science 251, 1236-1239
 |  Abstract »  |  PDF »

Wilms tumor locus on 11p13 defined by multiple CpG island-associated transcripts.

L Bonetta, S. Kuehn, A Huang, D. Law, L. Kalikin, M Koi, A. Reeve, B. Brownstein, H Yeger, B. Williams, et al. (1990)
Science 250, 994-997
 |  Abstract »  |  PDF »

Mapping the human genome: current status.

J. Stephens, M. Cavanaugh, M. Gradie, M. Mador, and K. Kidd (1990)
Science 250, 237-244
 |  Abstract »  |  PDF »

Cleaving yeast and Escherichia coli genomes at a single site.

M Koob and W Szybalski (1990)
Science 250, 271-273
 |  Abstract »  |  PDF »

Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: a model for human genome mapping.

E. Green and M. Olson (1990)
Science 250, 94-98
 |  Abstract »  |  PDF »

Direct cloning of human transcripts with HnRNA from hybrid cell lines.

L Corbo, J. Maley, D. Nelson, and C. Caskey (1990)
Science 249, 652-655
 |  Abstract »  |  PDF »

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients.

M. Wallace, D. Marchuk, L. Andersen, R Letcher, H. Odeh, A. Saulino, J. Fountain, A Brereton, J Nicholson, A. Mitchell, et al. (1990)
Science 249, 181-186
 |  Abstract »  |  PDF »

Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination.

W. Qiu, D de Bruin, B. Brownstein, R Pearse, and J. Ravetch (1990)
Science 248, 732-735
 |  Abstract »  |  PDF »

Mapping the Drosophila genome with yeast artificial chromosomes.

D Garza, J. Ajioka, D. Burke, and D. Hartl (1989)
Science 246, 641-646
 |  Abstract »  |  PDF »

A common language for physical mapping of the human genome.

M Olson, L Hood, C Cantor, and D Botstein (1989)
Science 245, 1434-1435
 |  PDF »

Identification of the cystic fibrosis gene: chromosome walking and jumping.

J. Rommens, M. Iannuzzi, B Kerem, M. Drumm, G Melmer, M Dean, R Rozmahel, J. Cole, D Kennedy, N Hidaka, et al. (1989)
Science 245, 1059-1065
 |  Abstract »  |  PDF »

Construction of large DNA segments in Escherichia coli.

M O'Connor, M Peifer, and W Bender (1989)
Science 244, 1307-1312
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Isolation of single-copy human genes from a library of yeast artificial chromosome clones.

B. Brownstein, G. Silverman, R. Little, D. Burke, S. Korsmeyer, D Schlessinger, and M. Olson (1989)
Science 244, 1348-1351
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Functional analysis of the papilloma virus E2 trans-activator in Saccharomyces cerevisiae..

P F Lambert, N Dostatni, A A McBride, M Yaniv, P M Howley, and B Arcangioli (1989)
Genes & Dev. 3, 38-48
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Conferring operator specificity on restriction endonucleases.

M Koob, E Grimes, and W Szybalski (1988)
Science 241, 1084-1086
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Life, Evolution, and the Pursuit of Single Photon Sensitivity.

M.W. Bitensky, M.M. Whalen, and D.C. Torney (1988)
Cold Spring Harb Symp Quant Biol 53, 303-311
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High-speed chromosome sorting.

J. Gray, P. Dean, J. Fuscoe, D. Peters, B. Trask, G. van den Engh, and M. Van Dilla (1987)
Science 238, 323-329
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