Science 16 January 1987: Vol. 235. no. 4786, pp. 352 - 354 DOI: 10.1126/science.3798117

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Articles

Melatonin as a Biomarker of Circadian Dysregulation.

D. K. Mirick and S. Davis (2008)
Cancer Epidemiol. Biomarkers Prev. 17, 3306-3313
 |  Abstract »  |  Full Text »  |  PDF »

Melatonin and Human Chronobiology.

A. J. Lewy (2007)
Cold Spring Harb Symp Quant Biol 72, 623-636
 |  Abstract »  |  PDF »

Presynaptic GABAB Receptors Regulate Retinohypothalamic Tract Synaptic Transmission by Inhibiting Voltage-Gated Ca2+ Channels.

M. G. Moldavan, R. P. Irwin, and C. N. Allen (2006)
J Neurophysiol 95, 3727-3741
 |  Abstract »  |  Full Text »  |  PDF »

The circadian basis of winter depression.

A. J. Lewy, B. J. Lefler, J. S. Emens, and V. K. Bauer (2006)
PNAS 103, 7414-7419
 |  Abstract »  |  Full Text »  |  PDF »

Photic Entrainment Is Altered in the 5-HT1B Receptor Knockout Mouse.

P. J. Sollars, M. D. Ogilvie, A. M. Simpson, and G. E. Pickard (2006)
J Biol Rhythms 21, 21-32
 |  Abstract »  |  PDF »

Aetiology and pathogenesis of mood disorders.

L. Sher (2003)
QJM 96, 309-313
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A Forced Desynchrony Study of Circadian Pacemaker Characteristics in Seasonal Affective Disorder.

K. M. Koorengevel, D. G. M. Beersma, J. A. den Boer, and R. H. van den Hoofdakker (2002)
J Biol Rhythms 17, 463-475
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A Circadian Signal of Change of Season in Patients With Seasonal Affective Disorder.

T. A. Wehr, W. C. Duncan Jr, L. Sher, D. Aeschbach, P. J. Schwartz, E. H. Turner, T. T. Postolache, and N. E. Rosenthal (2001)
Arch Gen Psychiatry 58, 1108-1114
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mPer1 and mPer2 Are Essential for Normal Resetting of the Circadian Clock.

U. Albrecht, B. Zheng, D. Larkin, Z. S. Sun, and C. C. Lee (2001)
J Biol Rhythms 16, 100-104
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Transition from Dim to Bright Light in the Morning Induces an Immediate Elevation of Cortisol Levels.

R. Leproult, E. F. Colecchia, M. L’Hermite-Balériaux, and E. Van Cauter (2001)
J. Clin. Endocrinol. Metab. 86, 151-157
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Circadian Time of Morning Light Administration and Therapeutic Response in Winter Depression.

J. S. Terman, M. Terman, E.-S. Lo, and T. B. Cooper (2001)
Arch Gen Psychiatry 58, 69-75
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A Randomized, Double-Blind, Placebo-Controlled Crossover Study of the Effect of Exogenous Melatonin on Delayed Sleep Phase Syndrome.

L. Kayumov, G. Brown, R. Jindal, K. Buttoo, and C. M. Shapiro (2001)
Psychosom Med 63, 40-48
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Melatonin Suppression by Light in Euthymic Bipolar and Unipolar Patients.

J. I. Nurnberger Jr, S. Adkins, D. K. Lahiri, A. Mayeda, K. Hu, A. Lewy, A. Miller, E. S. Bowman, M. J. Miller, N. L. Rau, et al. (2000)
Arch Gen Psychiatry 57, 572-579
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Commentary: Models of the Effect of Light on the Human Circadian System: Current State of the Art.

C. A. Czeisler and E. N. Brown (1999)
J Biol Rhythms 14, 539-544
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Mechanism-based inhibition of the melatonin rhythm enzyme: Pharmacologic exploitation of active site functional plasticity.

E. M. Khalil, J. De Angelis, M. Ishii, and P. A. Cole (1999)
PNAS 96, 12418-12423
 |  Abstract »  |  Full Text »  |  PDF »

The Endogenous Melatonin Profile as a Marker for Circadian Phase Position.

A. J. Lewy, N. L. Cutler, and R. L. Sack (1999)
J Biol Rhythms 14, 227-236
 |  Abstract »  |  PDF »

Melatonin Rhythm Observed throughout a Three-Cycle Bright-Light Stimulus Designed to Reset the Human Circadian Pacemaker.

T. L. Shanahan, R. E. Kronauer, J. F. Duffy, G. H. Williams, and C. A. Czeisler (1999)
J Biol Rhythms 14, 237-253
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Melatonin Suppression by Light in Humans Is Maximal When the Nasal Part of the Retina Is Illuminated.

E. K. Visser, D. G. M. Beersma, and S. Daan (1999)
J Biol Rhythms 14, 116-121
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A Turning Point for Seasonal Affective Disorder and Light Therapy Research?.

D. H. Avery (1998)
Arch Gen Psychiatry 55, 863-864
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A Controlled Trial of Timed Bright Light and Negative Air Ionization for Treatment of Winter Depression.

M. Terman, J. S. Terman, and D. C. Ross (1998)
Arch Gen Psychiatry 55, 875-882
 |  Abstract »  |  Full Text »  |  PDF »

Bright Light Treatment of Winter Depression: A Placebo-Controlled Trial.

C. I. Eastman, M. A. Young, L. F. Fogg, L. Liu, and P. M. Meaden (1998)
Arch Gen Psychiatry 55, 883-889
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Morning vs Evening Light Treatment of Patients With Winter Depression.

A. J. Lewy, V. K. Bauer, N. L. Cutler, R. L. Sack, S. Ahmed, K. H. Thomas, M. L. Blood, and J. M. L. Jackson (1998)
Arch Gen Psychiatry 55, 890-896
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Effect of the shift of the sleep-wake cycle on three robust endocrine markers of the circadian clock.

B. Goichot, L. Weibel, F. Chapotot, C. Gronfier, F. Piquard, and G. Brandenberger (1998)
Am J Physiol Endocrinol Metab 275, E243-E248
 |  Abstract »  |  Full Text »  |  PDF »

Disturbances in Hormonal Profiles of Night Workers during Their Usual Sleep and Work Times.

L. Weibel and G. Brandenberger (1998)
J Biol Rhythms 13, 202-208
 |  Abstract »  |  PDF »

Hormonal and Subjective Responses to Intravenous m-Chlorophenylpiperazine in Women With Seasonal Affective Disorder.

R. D. Levitan, A. S. Kaplan, G. M. Brown, F. J. Vaccarino, S. H. Kennedy, A. J. Levitt, and R. T. Joffe (1998)
Arch Gen Psychiatry 55, 244-249
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Is Perception of Light Useful to the Blind Patient?.

R. D. Ross (1998)
Arch Ophthalmol 116, 236-238
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Photic Regulation of Melatonin in Humans: Ocular and Neural Signal Transduction.

G. C. Brainard, M. D. Rollag, and J. P. Hanifin (1997)
J Biol Rhythms 12, 537-546
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Resetting the Melatonin Rhythm with Light in Humans.

T. L. Shanahan, J. M. Zeitzer, and C. A. Czeisler (1997)
J Biol Rhythms 12, 556-567
 |  Abstract »  |  PDF »

Exogenous Melatonin's Phase-Shifting Effects on the Endogenous Melatonin Profile in Sighted Humans: A Brief Review and Critique of the Literature.

A. J. Lewy and R. L. Sack (1997)
J Biol Rhythms 12, 588-594
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Salivary Melatonin as a Circadian Phase Marker: Validation and Comparison to Plasma Melatonin.

A. Voultsios, D. J. Kennaway, and D. Dawson (1997)
J Biol Rhythms 12, 457-466
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Effects of Meta-chlorophenylpiperazine Infusions in Patients With Seasonal Affective Disorder and Healthy Control Subjects: Diurnal Responses and Nocturnal Regulatory Mechanisms.

P. J. Schwartz, D. L. Murphy, T. A. Wehr, D. Garcia-Borreguero, D. A. Oren, D. E. Moul, N. Ozaki, A. J. Snelbaker, and N. E. Rosenthal (1997)
Arch Gen Psychiatry 54, 375-385
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Plasma Melatonin Circadian Rhythms during the Menstrual Cycle and after Light Therapy in Premenstrual Dysphoric Disorder and Normal Control Subjects.

B. L. Parry, S. L. Berga, N. Mostofi, M. R. Klauber, and A. Resnick (1997)
J Biol Rhythms 12, 47-64
 |  Abstract »  |  PDF »

Effects of Tryptophan Depletion on Drug-Free Patients With Seasonal Affective Disorder During a Stable Response to Bright Light Therapy.

A. Neumeister, N. Praschak-Rieder, B. Hesselmann, M.-L. Rao, J. Gluck, and S. Kasper (1997)
Arch Gen Psychiatry 54, 133-138
 |  Abstract »  |  PDF »

Complex Interaction of the Sleep-Wake Cycle and Circadian Phase Modulates Mood in Healthy Subjects.

D. B. Boivin, C. A. Czeisler, D.-J. Dijk, J. F. Duffy, S. Folkard, D. S. Minors, P. Totterdell, and J. M. Waterhouse (1997)
Arch Gen Psychiatry 54, 145-152
 |  Abstract »  |  PDF »

Lighting for neonatal intensive care units: Some critical information for design.

J. Bullough and M.S. Rea (1996)
Lighting Research and Technology 28, 189-198
 |  Abstract »  |  PDF »

Melatonin and Light Induce Phase Shifts of Circadian Activity Rhythms in the C3H/HeN Mouse.

S. Benloucif and M. L. Dubocovich (1996)
J Biol Rhythms 11, 113-125
 |  Abstract »  |  PDF »

Seasonal Changes in Mood and Behavior: The Role of Genetic Factors.

P. A. F. Madden, A. C. Heath, N. E. Rosenthal, and N. G. Martin (1996)
Arch Gen Psychiatry 53, 47-55
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Light Treatment for Sleep Disorders: Consensus Report: II. Basic Properties of Circadian Physiology and Sleep Regulation.

D.-J. Dijk, Z. Boulos, C. I. Eastman, A. J. Lewy, S. S. Campbell, and M. Terman (1995)
J Biol Rhythms 10, 113-125
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Light Treatment for Sleep Disorders: Consensus Report: IV. Sleep Phase and Duration Disturbances.

M. Terman, A. J. Lewy, D.-J. Dijk, Z. Boulos, C. I. Eastman, and S. S. Campbell (1995)
J Biol Rhythms 10, 135-147
 |  Abstract »  |  PDF »

Twenty-Four-Hour Rhythms in Relation to the Natural Photoperiod: A Field Study in Humans.

M.-L. Laakso, T. Porkka-Heiskanen, A. Alila, D. Stenberg, and G. Johansson (1994)
J Biol Rhythms 9, 283-293
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Diagnosis and Treatment of Seasonal Affective Disorder.

N. E. Rosenthal (1993)
JAMA 270, 2717-2720
 |  Abstract »  |  PDF »

Serendipity and Pseudoscience: A Look at Health-Related Program Evaluation.

D. Holmes, J. Teresi, and M. Ory (1993)
Eval Health Prof 16, 363-378
 |  Abstract »  |  PDF »

Light Therapy in Seasonal Affective Disorder Is Independent of Time of Day or Circadian Phase.

A. Wirz-Justice, P. Graw, K. Krauchi, B. Gisin, A. Jochum, J. Arendt, H.-U. Fisch, C. Buddeberg, and W. Poldinger (1993)
Arch Gen Psychiatry 50, 929-937
 |  Abstract »  |  PDF »

Review Paper: Fluorescent lighting and health.

P.T. Stone (1992)
Lighting Research and Technology 24, 55-61
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Melatonin Administration to Blind People: Phase Advances and Entrainment.

R. L. Sack, A. J. Lewy, M. L. Blood, J. Stevenson, and L. D. Keith (1991)
J Biol Rhythms 6, 249-261
 |  Abstract »  |  PDF »

Altered Waveform of Plasma Nocturnal Melatonin Secretion in Premenstrual Depression.

B. L. Parry, S. L. Berga, D. F. Kripke, M. R. Klauber, G. A. Laughlin, S. S. C. Yen, and J. C. Gillin (1990)
Arch Gen Psychiatry 47, 1139-1146
 |  Abstract »  |  PDF »

Affective Functioning, "Light Hunger," and Room Brightness Preferences.

J. H. Heerwagen (1990)
Environment and Behavior 22, 608-635
 |  Abstract »

Morning vs Evening Light Treatment for Winter Depression: Evidence That the Therapeutic Effects of Light Are Mediated by Circadian Phase Shifts.

R. L. Sack, A. J. Lewy, D. M. White, C. M. Singer, M. J. Fireman, and R. Vandiver (1990)
Arch Gen Psychiatry 47, 343-351
 |  Abstract »  |  PDF »

Seasonal Independence of Low Prolactin Concentration and High Spontaneous Eye Blink Rates in Unipolar and Bipolar II Seasonal Affective Disorder.

R. A. Depue, P. Arbisi, S. Krauss, W. G. Iacono, A. Leon, R. Muir, and J. Allen (1990)
Arch Gen Psychiatry 47, 356-364
 |  Abstract »  |  PDF »

Bright light induction of strong (type 0) resetting of the human circadian pacemaker.

C. Czeisler, R. Kronauer, J. Allan, J. Duffy, M. Jewett, E. Brown, and J. Ronda (1989)
Science 244, 1328-1333
 |  Abstract »  |  PDF »

Phototherapy for Seasonal Affective Disorder.

N. E. Rosenthal, D. A. Sack, R. G. Skwerer, F. M. Jacobsen, and T. A. Wehr (1988)
J Biol Rhythms 3, 101-120
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Winter Depression and the Phase-Shift Hypothesis for Bright Light's Therapeutic Effects: History, Theory, and Experimental Evidence.

A. J. Lewy, R. L. Sack, C. M. Singer, D. M. Whate, and T. M. Hoban (1988)
J Biol Rhythms 3, 121-134
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Neurobiology of Seasonal Affective Disorder and Phototherapy.

R. G. Skwerer, F. M. Jacobsen, C. C. Duncan, K. A. Kelly, D. A. Sack, L. Tamarkin, P. A. Gaist, S. Kasper, and N. E. Rosenthal (1988)
J Biol Rhythms 3, 135-154
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Neuroendocrine Response to 5-Hydroxytryptophan in Seasonal Affective Disorder.

F. M. Jacobsen, D. A. Sack, T. A. Wehr, S. Rogers, and N. E. Rosenthal (1987)
Arch Gen Psychiatry 44, 1086-1091
 |  Abstract »  |  PDF »

Importance of Timing and Duration of Phototherapy-Reply.

T. A. Wehr, D. A. Sack, and N. E. Rosenthal (1987)
Arch Gen Psychiatry 44, 921-923
 |  Abstract »  |  PDF »

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