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Science 16 January 1987: Vol. 235. no. 4786, pp. 305 - 311 DOI: 10.1126/science.3541204
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Articles
Science, Vol 235, Issue 4786, 305-311
Copyright © 1987 by American Association for the Advancement of Science
The molecular genetics of cancer
JM Bishop
The search for genetic damage in neoplastic cells now occupies a central place in cancer research. Diverse examples of such damage are in hand, and they in turn hint at biochemical explanations for neoplastic growth. The way may be open to solve the riddles of how normal cells govern their replication and why cancer cells do not.
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| Full Text »
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| Full Text »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
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| Full Text »
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10, 1930-1944
| Abstract »
| PDF »
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- D. S. Latchman (1996)
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334, 28-33
| Full Text »
| PDF »
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| Abstract »
| PDF »
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- J. E. Riggs (1995)
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| Abstract »
| PDF »
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- A Levitzki and A Gazit (1995)
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| Abstract »
| PDF »
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- R. Schiestl, F Khogali, and N Carls (1994)
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| Abstract »
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| Abstract »
| PDF »
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- Z Qian, M Gilbert, and E R Kandel (1994)
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1, 180-188
| Abstract »
| PDF »
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- D. Sidransky, J. Boyle, and W. Koch (1993)
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119, 1187-1190
| Abstract »
| PDF »
- Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells..
- C Ma, S Martin, B Trask, and J L Hamlin (1993)
Genes & Dev.
7, 605-620
| Abstract »
| PDF »
- Betacellulin: a mitogen from pancreatic beta cell tumors.
- Y Shing, G Christofori, D Hanahan, Y Ono, R Sasada, K Igarashi, and J Folkman (1993)
Science
259, 1604-1607
| Abstract »
| PDF »
- Loss of Chromosomal Integrity in Neoplasia.
- T.D. Tlsty, P. Jonczyk, A White, M. Sage, I. Hall, D. Schaefer, A. Briot, E. Livanos, H. Roelofs, B. Poulose, et al. (1993)
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58, 645-654
| Abstract »
| PDF »
- An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence..
- N Benvenisty, A Leder, A Kuo, and P Leder (1992)
Genes & Dev.
6, 2513-2523
| Abstract »
| PDF »
- Suppression of gene amplification in human cell hybrids.
- T. Tlsty, A White, and J Sanchez (1992)
Science
255, 1425-1427
| Abstract »
| PDF »
- Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes.
- E. Fischer, H Charbonneau, and N. Tonks (1991)
Science
253, 401-406
| Abstract »
| PDF »
- Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers.
- K. Kinzler, M. Nilbert, B Vogelstein, T. Bryan, D. Levy, K. Smith, A. Preisinger, Hamilton SR, P Hedge, A Markham, et al. (1991)
Science
251, 1366-1370
| Abstract »
| PDF »
- A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration..
- B Windle, B W Draper, Y X Yin, S O'Gorman, and G M Wahl (1991)
Genes & Dev.
5, 160-174
| Abstract »
| PDF »
- Genetic mechanisms of tumor suppression by the human p53 gene.
- P. Chen, Y. Chen, R Bookstein, and W. Lee (1990)
Science
250, 1576-1580
| Abstract »
| PDF »
- Oncogene Amplification in Squamous Cell Carcinoma of the Head and Neck.
- W. D. Merritt, M. C. Weissler, B. F. Turk, and T. M. Gilmer (1990)
Arch Otolaryngol Head Neck Surg
116, 1394-1398
| Abstract »
| PDF »
- Protein tyrosine phosphatase activity of an essential virulence determinant in Yersinia.
- K. Guan and J. Dixon (1990)
Science
249, 553-556
| Abstract »
| PDF »
- Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.
- K Zhang, M Noda, W. Vass, A. Papageorge, and D. Lowy (1990)
Science
249, 162-165
| Abstract »
| PDF »
- Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development..
- D Martin-Zanca, M Barbacid, and L F Parada (1990)
Genes & Dev.
4, 683-694
| Abstract »
| PDF »
- c-Ha-ras and UV Photocarcinogenesis: Do Rays Raise ras?.
- J. T. Elder (1990)
Arch Dermatol
126, 379-382
| Abstract »
| PDF »
- Identification of a chromosome 18q gene that is altered in colorectal cancers.
- E. Fearon, K. Cho, J. Nigro, S. Kern, J. Simons, J. Ruppert, Hamilton SR, A. Preisinger, G Thomas, K. Kinzler, et al. (1990)
Science
247, 49-56
| Abstract »
| PDF »
- Transgenic mice as probes into complex systems.
- D Hanahan (1989)
Science
246, 1265-1275
| Abstract »
| PDF »
- Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus..
- B J Trask and J L Hamlin (1989)
Genes & Dev.
3, 1913-1925
| Abstract »
| PDF »
- Checkpoints: controls that ensure the order of cell cycle events.
- L. Hartwell and T. Weinert (1989)
Science
246, 629-634
| Abstract »
| PDF »
- Fibroblasts transformed with v-src show enhanced formation of an inositol tetrakisphosphate.
- R. Johnson, W. Wasilenko, R. Mattingly, M. Weber, and J. Garrison (1989)
Science
246, 121-124
| Abstract »
| PDF »
- Environmental Exposures in Cytogenetically Defined Subsets of Acute Nonlymphocytic Leukemia.
- M. M. Crane, M. J. Keating, J. M. Trujillo, D. R. Labarthe, and R. F. Frankowski (1989)
JAMA
262, 634-639
| Abstract »
| PDF »
- Perturbed development of the mouse lens by polyomavirus large T antigen does not lead to tumor formation..
- A E Griep, T Kuwabara, E J Lee, and H Westphal (1989)
Genes & Dev.
3, 1075-1085
| Abstract »
| PDF »
- Healing, Regeneration, and Repair: Prospectus for New Dental Treatment.
- V.P. Terranova, M. Jendresen, and F. Young (1989)
Advances in Dental Research
3, 69-79
| Abstract »
| PDF »
- Immunosurveillance of Virus-induced Tumors.
- C.J.M. Melief, W.L.E. Vasmel, R. Offringa, E.J.A.M. Sijts, E.A. Matthews, P.J. Peters, R.H. Meloen, A.J. van der Eb, and W.M. Kast (1989)
Cold Spring Harb Symp Quant Biol
54, 597-603
| Abstract »
| PDF »
- Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.
- H. Huang, J. Yee, J. Shew, P. Chen, R Bookstein, T Friedmann, E. Lee, and W. Lee (1988)
Science
242, 1563-1566
| Abstract »
| PDF »
- DNA diagnostics--molecular techniques and automation.
- U Landegren, R Kaiser, C. Caskey, and L Hood (1988)
Science
242, 229-237
| Abstract »
| PDF »
- Inactivation of the retinoblastoma susceptibility gene in human breast cancers.
- E. Lee, H To, J. Shew, R Bookstein, P Scully, and W. Lee (1988)
Science
241, 218-221
| Abstract »
| PDF »
- Retroviruses.
- H Varmus (1988)
Science
240, 1427-1435
| Abstract »
| PDF »
- Transgenic animals.
- R Jaenisch (1988)
Science
240, 1468-1474
| Abstract »
| PDF »
- Voltage-sensitive calcium channels in normal and transformed 3T3 fibroblasts.
- C. Chen, M. Corbley, T. Roberts, and P Hess (1988)
Science
239, 1024-1026
| Abstract »
| PDF »
- Role of Intrinsic Protein Tyrosine Kinase in Function and Metabolism of the Epidermal Growth Factor Receptor.
- G.N. Gill, W.S. Chen, C.S. Lazar, J.R. Glenney Jr., H.S. Wiley, H.A. Ingraham, and M.G. Rosenfeld (1988)
Cold Spring Harb Symp Quant Biol
53, 467-476
| Abstract »
| PDF »
- Regulation of Proto-oncogene fos: A Paradigm for Early Response Genes.
- P. Sassone-Corsi, W.W. Lamph, and I.M. Verma (1988)
Cold Spring Harb Symp Quant Biol
53, 749-760
| Abstract »
| PDF »
- Characterization of p47gag-crk, a Novel Oncogene Product with Sequence Similarity to a Putative Modulatory Domain of Protein-Tyrosine Kinases and Phospholipase C.
- B.J. Mayer, M. Hamaguchi, and H. Hanafusa (1988)
Cold Spring Harb Symp Quant Biol
53, 907-914
| Abstract »
| PDF »
- A novel putative tyrosine kinase receptor encoded by the eph gene.
- H Hirai, Y Maru, K Hagiwara, J Nishida, and F Takaku (1987)
Science
238, 1717-1720
| Abstract »
| PDF »
- The approaching era of the tumor suppressor genes.
- G Klein (1987)
Science
238, 1539-1545
| Abstract »
| PDF »
- Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.
- D Bohmann, T. Bos, A Admon, T Nishimura, P. Vogt, and R Tjian (1987)
Science
238, 1386-1392
| Abstract »
| PDF »
- Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene.
- T. Velu, L Beguinot, W. Vass, M. Willingham, G. Merlino, I Pastan, and D. Lowy (1987)
Science
238, 1408-1410
| Abstract »
| PDF »
- Defects in lens fiber differentiation are linked to c-mos overexpression in transgenic mice..
- J S Khillan, M K Oskarsson, F Propst, T Kuwabara, G F Vande Woude, and H Westphal (1987)
Genes & Dev.
1, 1327-1335
| Abstract »
| PDF »
- Rapid stimulation of diacylglycerol production in Xenopus oocytes by microinjection of H-ras p21.
- J. Lacal, P de la Pena, J Moscat, P Garcia-Barreno, P. Anderson, and S. Aaronson (1987)
Science
238, 533-536
| Abstract »
| PDF »
- Disease diagnosis by recombinant DNA methods.
- C. Caskey (1987)
Science
236, 1223-1229
| Abstract »
| PDF »
- Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors.
- D. Burke, G. Carle, and M. Olson (1987)
Science
236, 806-812
| Abstract »
| PDF »
- Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression.
- B. Weissman, P. Saxon, Pasquale SR, G. Jones, A. Geiser, and E. Stanbridge (1987)
Science
236, 175-180
| Abstract »
| PDF »
- Human retinoblastoma susceptibility gene: cloning, identification, and sequence.
- W. Lee, R Bookstein, F Hong, L. Young, J. Shew, and E. Lee (1987)
Science
235, 1394-1399
| Abstract »
| PDF »
- Characterization of a Prostate-specific Tyrosine Phosphatase by Mutagenesis and Expression in Human Prostate Cancer Cells.
- X.-Q. Zhang, M.-S. Lee, S. Zelivianski, and M.-F. Lin (2001)
J. Biol. Chem.
276, 2544-2550
| Abstract »
| Full Text »
| PDF »
- Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks.
- M. J. Singer, L. D. Mesner, C. L. Friedman, B. J. Trask, and J. L. Hamlin (2000)
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97, 7921-7926
| Abstract »
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| PDF »
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