Related Content
Search Google Scholar for:
|
|
Science 10 October 1986: Vol. 234. no. 4773, pp. 161 - 166 DOI: 10.1126/science.3018928
|
|
Articles
Science, Vol 234, Issue 4773, 161-166
Copyright © 1986 by American Association for the Advancement of Science
Early signals in the mitogenic response
E Rozengurt
Polypeptide growth factors, regulatory peptides, and a variety of pharmacological agents acting alone or synergistically induce mitogenesis in cultured fibroblasts. The early signals in the membrane, cytosol, and nucleus promoted by these extracellular factors, together with their mitogenic effectiveness, are integrated in a unified hypothesis for the regulation of fibroblast growth.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Induction of early response genes in trypsin inhibitor-induced pancreatic growth.
- L. Guo, M. D. Sans, G. T. Gurda, S.-H. Lee, S. A. Ernst, and J. A. Williams (2007)
Am J Physiol Gastrointest Liver Physiol
292, G667-G677
| Abstract »
| Full Text »
| PDF »
- Novel cystogenic role of basic fibroblast growth factor in developing rodent kidneys.
- Z. Li, M. Jerebtsova, X.-H. Liu, P. Tang, and P. E. Ray (2006)
Am J Physiol Renal Physiol
291, F289-F296
| Abstract »
| Full Text »
| PDF »
- Qdot Nanocrystal Conjugates conjugated to bombesin or ANG II label the cognate G protein-coupled receptor in living cells.
- S. H. Young and E. Rozengurt (2006)
Am J Physiol Cell Physiol
290, C728-C732
| Abstract »
| Full Text »
| PDF »
- Mammalian G Proteins and Their Cell Type Specific Functions.
- N. Wettschureck and S. Offermanns (2005)
Physiol Rev
85, 1159-1204
| Abstract »
| Full Text »
| PDF »
- G Protein-coupled Receptor Activation Rapidly Stimulates Focal Adhesion Kinase Phosphorylation at Ser-843: MEDIATION BY Ca2+, CALMODULIN, AND Ca2+/CALMODULIN-DEPENDENT KINASE II.
- R. S. Fan, R. O. Jacamo, X. Jiang, J. Sinnett-Smith, and E. Rozengurt (2005)
J. Biol. Chem.
280, 24212-24220
| Abstract »
| Full Text »
| PDF »
- EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway.
- T. Chiu, C. Santiskulvong, and E. Rozengurt (2005)
Am J Physiol Gastrointest Liver Physiol
288, G182-G194
| Abstract »
| Full Text »
| PDF »
- Angiotensin II and Epidermal Growth Factor Induce Cyclooxygenase-2 Expression in Intestinal Epithelial Cells through Small GTPases Using Distinct Signaling Pathways.
- L. W. Slice, T. Chiu, and E. Rozengurt (2005)
J. Biol. Chem.
280, 1582-1593
| Abstract »
| Full Text »
| PDF »
- G Protein-coupled Receptor-mediated Phosphorylation of the Activation Loop of Protein Kinase D: DEPENDENCE ON PLASMA MEMBRANE TRANSLOCATION AND PROTEIN KINASE C{epsilon}.
- O. Rey, J. R. Reeve Jr., E. Zhukova, J. Sinnett-Smith, and E. Rozengurt (2004)
J. Biol. Chem.
279, 34361-34372
| Abstract »
| Full Text »
| PDF »
- Protein Kinase D Potentiates DNA Synthesis Induced by Gq-coupled Receptors by Increasing the Duration of ERK Signaling in Swiss 3T3 Cells.
- J. Sinnett-Smith, E. Zhukova, N. Hsieh, X. Jiang, and E. Rozengurt (2004)
J. Biol. Chem.
279, 16883-16893
| Abstract »
| Full Text »
| PDF »
- ERK Is Regulated by Sodium-Proton Exchanger in Rat Aortic Vascular Smooth Muscle Cells.
- Y. V. Mukhin, M. N. Garnovskaya, M. E. Ullian, and J. R. Raymond (2004)
J. Biol. Chem.
279, 1845-1852
| Abstract »
| Full Text »
| PDF »
- The Expression of the Thyroid-stimulating Hormone (TSH) Receptor and the cAMP-dependent Protein Kinase RII {beta} Regulatory Subunit Confers TSH-cAMP-dependent Growth to Mouse Fibroblasts.
- A. Porcellini, S. Messina, G. De Gregorio, A. Feliciello, A. Carlucci, M. Barone, A. Picascia, A. De Blasi, and E. V. Avvedimento (2003)
J. Biol. Chem.
278, 40621-40630
| Abstract »
| Full Text »
| PDF »
- Protein Kinase C{nu}/Protein Kinase D3 Nuclear Localization, Catalytic Activation, and Intracellular Redistribution in Response to G Protein-coupled Receptor Agonists.
- O. Rey, J. Yuan, S. H. Young, and E. Rozengurt (2003)
J. Biol. Chem.
278, 23773-23785
| Abstract »
| Full Text »
| PDF »
- Increased expression of protein kinase C isoforms in heart failure due to myocardial infarction.
- J. Wang, X. Liu, E. Sentex, N. Takeda, and N. S. Dhalla (2003)
Am J Physiol Heart Circ Physiol
284, H2277-H2287
| Abstract »
| Full Text »
| PDF »
- Elevated Akt Phosphorylation as an Indicator of Renal Tubular Epithelial Cell Stress.
- T. Nishino, C. D. Pusey, and J. Domin (2002)
J. Biol. Chem.
277, 33943-33949
| Abstract »
| Full Text »
| PDF »
- cAMP Inhibition of Akt Is Mediated by Activated and Phosphorylated Rap1b.
- L. Lou, J. Urbani, F. Ribeiro-Neto, and D. L. Altschuler (2002)
J. Biol. Chem.
277, 32799-32806
| Abstract »
| Full Text »
| PDF »
- On the mitogenic properties of Rap1b: cAMP-induced G1/S entry requires activated and phosphorylated Rap1b.
- F. Ribeiro-Neto, J. Urbani, N. Lemee, L. Lou, and D. L. Altschuler (2002)
PNAS
99, 5418-5423
| Abstract »
| Full Text »
| PDF »
- Neurotensin Induces Protein Kinase C-dependent Protein Kinase D Activation and DNA Synthesis in Human Pancreatic Carcinoma Cell Line PANC-1.
- S. Guha, O. Rey, and E. Rozengurt (2002)
Cancer Res.
62, 1632-1640
| Abstract »
| Full Text »
| PDF »
- Protein Kinase D Potentiates DNA Synthesis and Cell Proliferation Induced by Bombesin, Vasopressin, or Phorbol Esters in Swiss 3T3 Cells.
- E. Zhukova, J. Sinnett-Smith, and E. Rozengurt (2001)
J. Biol. Chem.
276, 40298-40305
| Abstract »
| Full Text »
| PDF »
- Proliferation, not apoptosis, alters epithelial cell migration in small intestine of CFTR null mice.
- A. M. Gallagher and R. A. Gottlieb (2001)
Am J Physiol Gastrointest Liver Physiol
281, G681-G687
| Abstract »
| Full Text »
| PDF »
- EGF receptor function is required in late G1 for cell cycle progression induced by bombesin and bradykinin.
- C. Santiskulvong, J. Sinnett-Smith, and E. Rozengurt (2001)
Am J Physiol Cell Physiol
281, C886-C898
| Abstract »
| Full Text »
| PDF »
- Activation of Phosphatidylinositol-3 Kinase (PI-3K) and Extracellular Regulated Kinases (Erk1/2) Is Involved in Muscarinic Receptor-Mediated DNA Synthesis in Neural Progenitor Cells.
- B.-S. Li, W. Ma, L. Zhang, J. L. Barker, D. A. Stenger, and H. C. Pant (2001)
J. Neurosci.
21, 1569-1579
| Abstract »
| Full Text »
| PDF »
- Requirement of cortical actin organization for bombesin, endothelin, and EGF receptor internalization.
- J. A. Lunn, H. Wong, E. Rozengurt, and J. H. Walsh (2000)
Am J Physiol Cell Physiol
279, C2019-C2027
| Abstract »
| Full Text »
| PDF »
- Comitogenic effect of catecholamines on rat cardiac fibroblasts in culture.
- M. Leicht, N. Greipel, and H.-G. Zimmer (2000)
Cardiovasc Res
48, 274-284
| Abstract »
| Full Text »
| PDF »
- Inhibition of Cyclooxygenase-2 Decreases DNA Synthesis Induced by Platelet-Derived Growth Factor in Swiss 3T3 Fibroblasts.
- E. Castaño, R. Bartrons, and J. Gil (2000)
J. Pharmacol. Exp. Ther.
293, 509-513
| Abstract »
| Full Text »
- Prostaglandin E2-Induced Up-Regulation of c-fos Messenger Ribonucleic Acid Is Primarily Mediated by 3',5'-Cyclic Adenosine Monophosphate in MC3T3-E1 Osteoblasts.
- J. Fitzgerald, T. J. Dietz, and M. Hughes-Fulford (2000)
Endocrinology
141, 291-298
| Abstract »
| Full Text »
| PDF »
- Sodium-Potassium-Chloride Cotransport.
- J. M. Russell (2000)
Physiol Rev
80, 211-276
| Abstract »
| Full Text »
| PDF »
- Bombesin and Platelet-derived Growth Factor Induce Association of Endogenous Focal Adhesion Kinase with Src in Intact Swiss 3T3 Cells.
- E. P. Salazar and E. Rozengurt (1999)
J. Biol. Chem.
274, 28371-28378
| Abstract »
| Full Text »
| PDF »
- Production of Angiotensin II by Homogeneous Cultures of Vascular Smooth Muscle Cells From Spontaneously Hypertensive Rats.
- N. Fukuda, C. Satoh, W.-Y. Hu, M. Soma, A. Kubo, H. Kishioka, Y. Watanabe, Y. Izumi, and K. Kanmatsuse (1999)
Arterioscler. Thromb. Vasc. Biol.
19, 1210-1217
| Abstract »
| Full Text »
| PDF »
- Physiological significance of volume-regulatory transporters.
- W. C. O'Neill (1999)
Am J Physiol Cell Physiol
276, C995-C1011
| Abstract »
| Full Text »
| PDF »
- The Pleckstrin Homology Domain of Protein Kinase D Interacts Preferentially with the eta Isoform of Protein Kinase C.
- R. T. Waldron, T. Iglesias, and E. Rozengurt (1999)
J. Biol. Chem.
274, 9224-9230
| Abstract »
| Full Text »
| PDF »
- The Matrix Metalloproteinase-9 Regulates the Insulin-like Growth Factor-triggered Autocrine Response in DU-145 Carcinoma Cells.
- S. Manes, M. Llorente, R. A. Lacalle, C. Gomez-Mouton, L. Kremer, E. Mira, and C. Martinez-A (1999)
J. Biol. Chem.
274, 6935-6945
| Abstract »
| Full Text »
| PDF »
- Lysophosphatidic Acid Activates NF-kappa B in Fibroblasts. A REQUIREMENT FOR MULTIPLE INPUTS.
- M. Shahrestanifar, X. Fan, and D. R. Manning (1999)
J. Biol. Chem.
274, 3828-3833
| Abstract »
| Full Text »
| PDF »
- Identity of adenylyl cyclase isoform determines the rate of cell cycle progression in NIH 3T3 cells.
- M. J. Smit, D. Verzijl, and R. Iyengar (1998)
PNAS
95, 15084-15089
| Abstract »
| Full Text »
| PDF »
- Bombesin, Vasopressin, Lysophosphatidic Acid, and Sphingosylphosphorylcholine Induce Focal Adhesion Kinase Activation in Intact Swiss 3T3 Cells.
- J. L. Rodriguez-Fernandez and E. Rozengurt (1998)
J. Biol. Chem.
273, 19321-19328
| Abstract »
| Full Text »
| PDF »
- Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival.
- J. R. Van Brocklyn, M.-J. Lee, R. Menzeleev, A. Olivera, L. Edsall, O. Cuvillier, D. M. Thomas, P. J.P. Coopman, S. Thangada, C. H. Liu, et al. (1998)
J. Cell Biol.
142, 229-240
| Abstract »
| Full Text »
| PDF »
- Increased Protein Kinase C Activity in Myotrophin-Induced Myocyte Growth.
- P. Sil, V. Kandaswamy, and S. Sen (1998)
Circ. Res.
82, 1173-1188
| Abstract »
| Full Text »
| PDF »
- Protein Kinase C Mediates the Mitogenic Action of Thrombopoietin in c-Mpl-Expressing UT-7 Cells.
- Y. Hong, D. Dumenil, B. van der Loo, F. Goncalves, W. Vainchenker, and J. D. Erusalimsky (1998)
Blood
91, 813-822
| Abstract »
| Full Text »
| PDF »
- The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades.
- J. S. Gutkind (1998)
J. Biol. Chem.
273, 1839-1842
| Full Text »
| PDF »
- Protein Kinase D Activation by Mutations within Its Pleckstrin Homology Domain.
- T. Iglesias and E. Rozengurt (1998)
J. Biol. Chem.
273, 410-416
| Abstract »
| Full Text »
| PDF »
- Cyclic AMP-mediated Inhibition of Angiotensin II-induced Protein Synthesis Is Associated with Suppression of Tyrosine Phosphorylation Signaling in Vascular Smooth Muscle Cells.
- E. Giasson, M. J. Servant, and S. Meloche (1997)
J. Biol. Chem.
272, 26879-26886
| Abstract »
| Full Text »
| PDF »
- Low density lipoprotein enhances the thrombin-induced growth of vascular smooth muscle cells.
- S. Seewald, G. Nickenig, Y. Ko, H. Vetter, and A. Sachinidis (1997)
Cardiovasc Res
36, 92-100
| Abstract »
| Full Text »
| PDF »
- Bombesin, Vasopressin, Endothelin, Bradykinin, and Platelet-derived Growth Factor Rapidly Activate Protein Kinase D through a Protein Kinase C-dependent Signal Transduction Pathway.
- J. L. Zugaza, R. T. Waldron, J. Sinnett-Smith, and E. Rozengurt (1997)
J. Biol. Chem.
272, 23952-23960
| Abstract »
| Full Text »
| PDF »
- Tyrosine Phosphorylation of p130cas by Bombesin, Lysophosphatidic Acid, Phorbol Esters, and Platelet-derived Growth Factor. SIGNALING PATHWAYS AND FORMATION OF A p130cas-Crk COMPLEX.
- A. Casamassima and E. Rozengurt (1997)
J. Biol. Chem.
272, 9363-9370
| Abstract »
| Full Text »
| PDF »
- 5-HT1A Receptor Activates Na+/H+ Exchange in CHO-K1 Cells through Gialpha 2 and Gialpha 3.
- M. N. Garnovskaya, T. W. Gettys, T. van Biesen, V. Prpic, J. K. Chuprun, and J. R. Raymond (1997)
J. Biol. Chem.
272, 7770-7776
| Abstract »
| Full Text »
| PDF »
- Stimulation of the Mitogen-activated Protein Kinase via the A2A-Adenosine Receptor in Primary Human Endothelial Cells.
- V. Sexl, G. Mancusi, C. Holler, E. Gloria-Maercker, W. Schutz, and M. Freissmuth (1997)
J. Biol. Chem.
272, 5792-5799
| Abstract »
| Full Text »
| PDF »
- A Benzo[a]pyrene-induced Cell Cycle Checkpoint Resulting in p53-independent G1 Arrest in 3T3 Fibroblasts.
- C. Vaziri and D. V. Faller (1997)
J. Biol. Chem.
272, 2762-2769
| Abstract »
| Full Text »
| PDF »
- Effect of Growth Factors on the Expression of 6-Phosphofructo2-kinase/Fructose-2,6-bisphosphatase in Rat-1 Fibroblasts.
- M. Joaquin, C. Salvado, B. Bellosillo, A. J. Lange, J. Gil, and A. Tauler (1997)
J. Biol. Chem.
272, 2846-2851
| Abstract »
| Full Text »
| PDF »
- Rapamycin Dissociates p70S6K Activation from DNA Synthesis Stimulated by Bombesin and Insulin in Swiss 3T3 Cells.
- D. J. Withers, T. Seufferlein, D. Mann, B. Garcia, N. Jones, and E. Rozengurt (1997)
J. Biol. Chem.
272, 2509-2514
| Abstract »
| Full Text »
| PDF »
- Inhibition of DNA Synthesis by Aspirin in Swiss 3T3 Fibroblasts.
- E. Castaño, M. Dalmau, M. Martí, F. Berrocal, R. Bartrons, and J. Gil (1997)
J. Pharmacol. Exp. Ther.
280, 366-372
| Abstract »
| Full Text »
- Agonist Activation of delta -Opioid Receptor but not {micro}-Opioid Receptor Potentiates Fetal Calf Serum or Tyrosine Kinase Receptor-Mediated Cell Proliferation in a CellLine-Specific Manner.
- P. Y. Law, T. M. McGinn, K. M. Campbell, L. E. Erickson, and H.H. Loh (1997)
Mol. Pharmacol.
51, 152-160
| Abstract »
| Full Text »
- Cholesterol Enhances Platelet-Derived Growth Factor-BB-Induced [Ca2+]i and DNA Synthesis in Rat Aortic Smooth Muscle Cells.
- A. Sachinidis, M. Liu, A.-A. Weber, C. Seul, V. Harth, S. Seewald, Y. Ko, and H. Vetter (1997)
Hypertension
29, 326-333
| Abstract »
| Full Text »
| PDF »
- [D-Arg1,D-Trp5,7,9,Leu11]Substance P Coordinately and Reversibly Inhibits Bombesin- and Vasopressin-induced Signal Transduction Pathways in Swiss 3T3 Cells.
- M. J. Seckl, T. Higgins, and E. Rozengurt (1996)
J. Biol. Chem.
271, 29453-29460
| Abstract »
| Full Text »
| PDF »
- Bombesin, Bradykinin, Vasopressin, and Phorbol Esters Rapidly and Transiently Activate Src Family Tyrosine Kinases in Swiss 3T3 Cells. DISSOCIATION FROM TYROSINE PHOSPHORYLATION OF p125 FOCAL ADHESION KINASE.
- J. L. Rodriguez-Fernandez and E. Rozengurt (1996)
J. Biol. Chem.
271, 27895-27901
| Abstract »
| Full Text »
| PDF »
- Expression of the Aryl Hydrocarbon Receptor Is Regulated by Serum and Mitogenic Growth Factors in Murine 3T3 Fibroblasts.
- C. Vaziri, A. Schneider, D. H. Sherr, and D. V. Faller (1996)
J. Biol. Chem.
271, 25921-25927
| Abstract »
| Full Text »
| PDF »
- Modulation of the Inhibitory Substrate Properties of Oligodendrocytes by Platelet-Derived Growth Factor.
- D. M. Lang, M. G. Hille, M. E. Schwab, and C. A. O. Stuermer (1996)
J. Neurosci.
16, 5741-5748
| Abstract »
| Full Text »
| PDF »
- Reduced Requirement of Mitogen-activated Protein Kinase (MAPK) Activity for Entry into the S Phase of the Cell Cycle in Swiss 3T3 Fibroblasts Stimulated by Bombesin and Insulin.
- T. Seufferlein, D. J. Withers, and E. Rozengurt (1996)
J. Biol. Chem.
271, 21471-21477
| Abstract »
| Full Text »
| PDF »
- Binding to the Platelet-derived Growth Factor Receptor Transiently Activates the p85alpha -p110alpha Phosphoinositide 3-Kinase Complex in Vivo.
- J. Domin, R. Dhand, and M. D. Waterfield (1996)
J. Biol. Chem.
271, 21614-21621
| Abstract »
| Full Text »
| PDF »
- Stimulation of Mitogen-activated Protein Kinase and Na+/H+ Exchanger in Human Platelets. DIFFERENTIAL EFFECT OF PHORBOL ESTER AND VASOPRESSIN.
- O. Aharonovitz and Y. Granot (1996)
J. Biol. Chem.
271, 16494-16499
| Abstract »
| Full Text »
| PDF »
- The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase and c-Jun NH(2)-terminal Kinase Groups of Mitogen-activated Protein Kinases.
- P. S. Shapiro, J. N. Evans, R. J. Davis, and J. A. Posada (1996)
J. Biol. Chem.
271, 5750-5754
| Abstract »
| Full Text »
| PDF »
- Integrin-dependent induction of early growth response genes in capillary endothelial cells.
- L. Dike and D. Ingber (1996)
J. Cell Sci.
109, 2855-2863
| Abstract »
| PDF »
- Enhanced Growth of Cultured Fibroblasts by a Synthetic Polyanionic Polymer.
- T. Sawa, Y. Okumura, J. Sunamoro, J. L. Ding, and R. M. Ottenbrite (1996)
Journal of Bioactive and Compatible Polymers
11, 17-27
| Abstract »
- Vasoactive Diadenosine Polyphosphates Promote Growth of Cultured Renal Mesangial Cells.
- E. Schulze-Lohoff, S. Zanner, A. Ogilvie, and R. B. Sterzel (1995)
Hypertension
26, 899-904
| Abstract »
| Full Text »
- Activation of p70 S6 Kinase and erk-encoded Mitogen-activated Protein Kinases Is Resistant to High Cyclic Nucleotide Levels in Swiss 3T3 Fibroblasts.
- C. Petritsch, Rüd. Woscholski, H. M. L. Edelmann, and L. M. Ballou (1995)
J. Biol. Chem.
270, 26619-26625
| Abstract »
| Full Text »
| PDF »
- HDL3 Stimulates Multiple Signaling Pathways in Human Skin Fibroblasts.
- M. Walter, H. Reinecke, J.-R. Nofer, U. Seedorf, and G. Assmann (1995)
Arterioscler. Thromb. Vasc. Biol.
15, 1975-1986
| Abstract »
| Full Text »
- Thromboxane A2 and Vascular Smooth Muscle Cell Proliferation.
- A. Sachinidis, M. Flesch, Y. Ko, K. Schror, M. Bohm, R. Dusing, and H. Vetter (1995)
Hypertension
26, 771-780
| Abstract »
| Full Text »
- Ca[IMAGE]bulletCalmodulin Prevents Myristoylated Alanine-rich Kinase C Substrate Protein Phosphorylation by Protein Kinase Cs in C6 Rat Glioma Cells.
- B. R. Chakravarthy, R. J. Isaacs, P. Morley, and J. F. Whitfield (1995)
J. Biol. Chem.
270, 24911-24916
| Abstract »
| Full Text »
| PDF »
- Sphingosylphosphorylcholine Activation of Mitogen-activated Protein Kinase in Swiss 3T3 Cells Requires Protein Kinase C and a Pertussis Toxin-sensitive G Protein.
- T. Seufferlein and E. Rozengurt (1995)
J. Biol. Chem.
270, 24334-24342
| Abstract »
| Full Text »
| PDF »
- Dissociation of cAMP-stimulated Mitogenesis from Activation of the Mitogen-activated Protein Kinase Cascade in Swiss 3T3 Cells.
- D. J. Withers, S. R. Bloom, and E. Rozengurt (1995)
J. Biol. Chem.
270, 21411-21419
| Abstract »
| Full Text »
| PDF »
- Basic Fibroblast Growth Factor Activates Calcium Channels in Neonatal Rat Cardiomyocytes.
- P.-L. Merle, J.-J. Feige, and J. Verdetti (1995)
J. Biol. Chem.
270, 17361-17367
| Abstract »
| Full Text »
| PDF »
- The Moloney Leukemia Retroviral Long Terminal Repeat trans-Activates AP-1-inducible Genes and AP-1 Transcription Factor Binding.
- H. Weng, S.-Y. Choi, and D. V. Faller (1995)
J. Biol. Chem.
270, 13637-13644
| Abstract »
| Full Text »
| PDF »
- Tissue Inhibitor of Metalloproteinase-2 Stimulates Fibroblast Proliferation via a cAMP-dependent Mechanism.
- M. L. Corcoran and W. G. Stetler-Stevenson (1995)
J. Biol. Chem.
270, 13453-13459
| Abstract »
| Full Text »
| PDF »
- Involvement of a Pertussis Toxin-sensitive G Protein in the Mitogenic Signaling Pathways of Sphingosine 1-Phosphate.
- K. A. Goodemote, M. E. Mattie, A. Berger, and S. Spiegel (1995)
J. Biol. Chem.
270, 10272-10277
| Abstract »
| Full Text »
| PDF »
- Differential Modulation of Bombesin-stimulated Phospholipase C[IMAGE] and Mitogen-activated Protein Kinase Activity by [ D-Arg[IMAGE], D-Phe[IMAGE], D-Trp[IMAGE],Leu[IMAGE]]Substance P.
- F. M. Mitchell, L. E. Heasley, N.-X. Qian, J. Zamarripa, and G. L. Johnson (1995)
J. Biol. Chem.
270, 8623-8628
| Abstract »
| Full Text »
| PDF »
- Guanosine 5`-3-O-(Thio)triphosphate Stimulates Tyrosine Phosphorylation of p125[IMAGE] and Paxillin in Permeabilized Swiss 3T3 Cells.
- M. J. Seckl, N. Morii, S. Narumiya, and E. Rozengurt (1995)
J. Biol. Chem.
270, 6984-6990
| Abstract »
| Full Text »
| PDF »
- Residual 201Tl Activity in Irreversible Defects as a Marker of Myocardial Viability : Clinicopathological Study.
- R. Zimmermann, G. Mall, B. Rauch, G. Zimmer, M. Gabel, J. Zehelein, B. Bubeck, H. Tillmanns, S. Hagl, and W. Kubler (1995)
Circulation
91, 1016-1021
| Abstract »
| Full Text »
- Expression and Characterization of PKD, a Phorbol Ester and Diacylglycerol-stimulated Serine Protein Kinase.
- J. Van Lint, J. Sinnett-Smith, and E. Rozengurt (1995)
J. Biol. Chem.
270, 1455-1461
| Abstract »
| Full Text »
| PDF »
- Cell spreading and the regulation of ornithine decarboxylase.
- R. Morrison and E. Seidel (1995)
J. Cell Sci.
108, 3787-3794
| Abstract »
| PDF »
- Current Issues in Cancer: Cancer chemotherapy: identifying novel anticancer drugs.
- J Carmichael (1994)
BMJ
308, 1288-1290
| Full Text »
- Inhibition by cAMP of Ras-dependent activation of Raf.
- S. Cook and F McCormick (1993)
Science
262, 1069-1072
| Abstract »
| PDF »
- The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation.
- M. J. Clemens, I. Trayner, and J. Menaya (1992)
J. Cell Sci.
103, 881-887
| PDF »
- T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation.
- T Mustelin, K. Coggeshall, N Isakov, and A Altman (1990)
Science
247, 1584-1587
| Abstract »
| PDF »
- Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD.
- C Sardet, L Counillon, A Franchi, and J Pouyssegur (1990)
Science
247, 723-726
| Abstract »
| PDF »
- G1 events and regulation of cell proliferation.
- A. Pardee (1989)
Science
246, 603-608
| Abstract »
| PDF »
- Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro..
- D E Levy, D S Kessler, R Pine, and J E Darnell (1989)
Genes & Dev.
3, 1362-1371
| Abstract »
| PDF »
- Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins.
- P. Mitchell and R Tjian (1989)
Science
245, 371-378
| Abstract »
| PDF »
- Induction of mesoderm by a viral oncogene in early Xenopus embryos.
- M Whitman and D. Melton (1989)
Science
244, 803-806
| Abstract »
| PDF »
- Role of Na+/H+ exchange by interferon-gamma in enhanced expression of JE and I-A beta genes.
- V Prpic, S. Yu, F Figueiredo, P. Hollenbach, G Gawdi, B Herman, R. Uhing, and D. Adams (1989)
Science
244, 469-471
| Abstract »
| PDF »
- Structure and function of human amphiregulin: a member of the epidermal growth factor family.
- M Shoyab, G. Plowman, V. McDonald, J. Bradley, and G. Todaro (1989)
Science
243, 1074-1076
| Abstract »
| PDF »
- Novel regulators of bone formation: molecular clones and activities.
- J. Wozney, V Rosen, A. Celeste, L. Mitsock, M. Whitters, R. Kriz, R. Hewick, and E. Wang (1988)
Science
242, 1528-1534
| Abstract »
| PDF »
- Potassium salt microinjection into Xenopus oocytes mimics gonadotropin treatment.
- Y. Lau, R. Yassin, and S. Horowitz (1988)
Science
240, 1321-1323
| Abstract »
| PDF »
- The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP..
- M Z Gilman (1988)
Genes & Dev.
2, 394-402
| Abstract »
| PDF »
- Mitogenesis in response to PDGF and bombesin abolished by microinjection of antibody to PIP2.
- K Matuoka, K Fukami, O Nakanishi, S Kawai, and T Takenawa (1988)
Science
239, 640-643
| Abstract »
| PDF »
- Rapid Ca2+ Influx and Diacylglycerol Synthesis in Growth Hormone-mediated Islet beta -Cell Mitogenesis.
- A. Sjoholm, Q. Zhang, N. Welsh, A. Hansson, O. Larsson, M. Tally, and P.-O. Berggren (2000)
J. Biol. Chem.
275, 21033-21040
| Abstract »
| Full Text »
| PDF »
- [D-Arg1,D-Trp5,7,9,Leu11]Substance P Inhibits Bombesin-induced Mitogenic Signal Transduction Mediated by Both Gq and G12 in Swiss 3T3 Cells.
- J. Sinnett-Smith, C. Santiskulvong, J. Duque, and E. Rozengurt (2000)
J. Biol. Chem.
275, 30644-30652
| Abstract »
| |