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Science 12 September 1986:
Vol. 233. no. 4769, pp. 1195 - 1197
DOI: 10.1126/science.2426783
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Articles
Science, Vol 233, Issue 4769, 1195-1197
Copyright © 1986 by American Association for the Advancement of Science
Ion channels in yeast
MC Gustin,
B Martinac,
Y Saimi,
MR Culbertson,
and
C Kung
Voltage-dependent ion channels have been found in the plasma membrane of the yeast Saccharomyces cerevisiae. Ion channel activities were recorded from spheroplasts or patches of plasma membrane with the patch-clamp technique. The most prominent activities came from a set of potassium channels with the properties of activation by positive but not negative voltages, high selectivity for potassium over sodium ion, unit conductance of 20 picosiemens, inhibition by tetraethylammonium or barium ions, and bursting kinetics.
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