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Science 11 July 1986:
Vol. 233. no. 4760, pp. 195 - 197
DOI: 10.1126/science.3726529
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Articles

Science, Vol 233, Issue 4760, 195-197
Copyright © 1986 by American Association for the Advancement of Science

articles

Time-resolved X-ray diffraction studies of the B in equilibrium D structural transition in the DNA double helix

A Mahendrasingam, VT Forsyth, R Hussain, RJ Greenall, WJ Pigram, and W Fuller

Because of the relation between topology and function, there has been much interest in the structural transitions of the various conformations of DNA polymers. The x-ray fiber diffraction analysis system at the Daresbury Synchrotron Radiation Source was used to study the reversible transition between the B and D forms of the synthetic DNA poly[d(A-T)].poly[d(A-T)]. The gradual progression of conformations between these two forms indicates that the DNA double helix does not undergo a change of handedness during this transition.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Ion Channels in Paramecium, Yeast, and Escherichia coli.
Y. Saimi, B. Martinac, M.C. Gustin, M.R. Culbertson, J. Adler, and C. Kung (1988)
Cold Spring Harb Symp Quant Biol 53, 667-673
   Abstract »    PDF »
Time-resolved x-ray diffraction of biological materials.
S. Gruner (1987)
Science 238, 305-312
   Abstract »    PDF »


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