Viral shedding and transmission between hosts determined by reovirus L2 gene

doi:10.1126/science.3012780

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Science 27 June 1986:
Vol. 232. no. 4758, pp. 1635 - 1638
DOI: 10.1126/science.3012780

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Science, Vol 232, Issue 4758, 1635-1638
Copyright © 1986 by American Association for the Advancement of Science

articles

Viral shedding and transmission between hosts determined by reovirus L2 gene

M Keroack and BN Fields

Two reovirus isolates (type 1 Lang and type 3 Dearing) differ in their transmissibility between littermates of newborn mice. They also differ in the amounts of virus excreted by the gastrointestinal tract. With the use of reassortant viruses, these properties were mapped to the L2 gene. Thus environmental spread of reovirus is a genetic property.

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