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Science 27 June 1986:
Vol. 232. no. 4758, pp. 1612 - 1619
DOI: 10.1126/science.3086978
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Articles

Science, Vol 232, Issue 4758, 1612-1619
Copyright © 1986 by American Association for the Advancement of Science

articles

Mechanisms of memory

LR Squire

Recent studies of animals with complex nervous systems, including humans and other primates, have improved our understanding of how the brain accomplishes learning and memory. Major themes of recent work include the locus of memory storage, the taxonomy of memory, the distinction between declarative and procedural knowledge, and the question of how memory changes with time, that is, the concepts of forgetting and consolidation. An important recent advance is the development of an animal model of human amnesia in the monkey. The animal model, together with newly available neuropathological information from a well-studied human patient, has permitted the identification of brain structures and connections involved in memory functions.


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