Science 23 May 1986: Vol. 232. no. 4753, pp. 977 - 980 DOI: 10.1126/science.3754653

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Articles

An Atypical Protein Kinase C (PKC{zeta}) Plays a Critical Role in Lipopolysaccharide-Activated NF-{kappa}B in Human Peripheral Blood Monocytes and Macrophages.

X. Huang, L.-Y. Chen, A. M. Doerner, W. W. Pan, L. Smith, S. Huang, T. J. Papadimos, and Z. K. Pan (2009)
J. Immunol. 182, 5810-5815
 |  Abstract »  |  Full Text »  |  PDF »

TLRs and innate immunity.

B. A. Beutler (2009)
Blood 113, 1399-1407
 |  Abstract »  |  Full Text »  |  PDF »

Repression of Repulsive Guidance Molecule C during Inflammation Is Independent of Hfe and Involves Tumor Necrosis Factor-{alpha}.

M. Constante, D. Wang, V.-A. Raymond, M. Bilodeau, and M. M. Santos (2007)
Am. J. Pathol. 170, 497-504
 |  Abstract »  |  Full Text »  |  PDF »

AU-rich elements and associated factors: are there unifying principles?.

C. Barreau, L. Paillard, and H. B. Osborne (2006)
Nucleic Acids Res. 33, 7138-7150
 |  Abstract »  |  Full Text »  |  PDF »

The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription.

P. J. Murray (2005)
PNAS 102, 8686-8691
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of calves exhibiting a novel inheritable TNF-{alpha} hyperresponsiveness to endotoxin: associations with increased pathophysiological complications.

T. H. Elsasser, J. W. Blum, and S. Kahl (2005)
J Appl Physiol 98, 2045-2055
 |  Abstract »  |  Full Text »  |  PDF »

The Function of Mitogen-activated Protein Kinase Phosphatase-1 in Peptidoglycan-stimulated Macrophages.

E. G. Shepherd, Q. Zhao, S. E. Welty, T. N. Hansen, C. V. Smith, and Y. Liu (2004)
J. Biol. Chem. 279, 54023-54031
 |  Abstract »  |  Full Text »  |  PDF »

Hypothermia prolongs activation of NF-{kappa}B and augments generation of inflammatory cytokines.

K. D. Fairchild, I. S. Singh, S. Patel, B. E. Drysdale, R. M. Viscardi, L. Hester, H. M. Lazusky, and J. D. Hasday (2004)
Am J Physiol Cell Physiol 287, C422-C431
 |  Abstract »  |  Full Text »  |  PDF »

Exercise as a Time-conditioning Effector in Chronic Disease: a Complementary Treatment Strategy.

L. F. B. P. Costa Rosa (2004)
Evid. Based Complement. Altern. Med. 1, 63-70
 |  Abstract »  |  Full Text »  |  PDF »

Review: D-Galactosamine lethality model: scope and limitations.

R. Silverstein (2004)
Innate Immunity 10, 147-162
 |  Abstract »  |  PDF »

Defective macrophage function in neonates and its impact on unresponsiveness of neonates to polysaccharide antigens.

R. L. Chelvarajan, S. M. Collins, I. E. Doubinskaia, S. Goes, J. Van Willigen, D. Flanagan, W. J. S. de Villiers, J. S. Bryson, and S. Bondada (2004)
J. Leukoc. Biol. 75, 982-994
 |  Abstract »  |  Full Text »  |  PDF »

Molecular cloning and characterization of mouse LITAF cDNA: role in the regulation of tumor necrosis factor-{alpha} (TNF-{alpha}) gene expression.

A.-L. Bolcato-Bellemin, M.-G. Mattei, M. Fenton, and S. Amar (2004)
Innate Immunity 10, 15-23
 |  Abstract »  |  PDF »

Age-dependent decrease in Toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression.

E. D. Boehmer, J. Goral, D. E. Faunce, and E. J. Kovacs (2004)
J. Leukoc. Biol. 75, 342-349
 |  Abstract »  |  Full Text »  |  PDF »

Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway.

J. F. Alcorn and J. R. Wright (2004)
Am J Physiol Lung Cell Mol Physiol 286, L129-L136
 |  Abstract »  |  Full Text »  |  PDF »

Prevention of Lipopolysaccharide-induced Microangiopathy by gp49B1: Evidence for an Important Role for gp49B1 Expression on Neutrophils.

J. S. Zhou, D. S. Friend, A. M. Feldweg, M. Daheshia, L. Li, K. F. Austen, and H. R. Katz (2003)
J. Exp. Med. 198, 1243-1251
 |  Abstract »  |  Full Text »  |  PDF »

Role of Toll-Like Receptor 4 in Macrophage Activation and Tolerance during Salmonella enterica Serovar Typhimurium Infection.

Q. Li and B. J. Cherayil (2003)
Infect. Immun. 71, 4873-4882
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of Toll-Like Receptor 4 by Lipopolysaccharide During Cellular Invasion by Live Salmonella typhimurium Is a Critical But Not Exclusive Event Leading to Macrophage Responses.

M. C. J. Royle, S. Totemeyer, L. C. Alldridge, D. J. Maskell, and C. E. Bryant (2003)
J. Immunol. 170, 5445-5454
 |  Abstract »  |  Full Text »  |  PDF »

Endogenous versus exogenous glucocorticoid responses to experimental bacterial sepsis.

R. Silverstein and D. C. Johnson (2003)
J. Leukoc. Biol. 73, 417-427
 |  Abstract »  |  Full Text »  |  PDF »

Prior burn insult induces lethal acute lung injury in endotoxemic mice: effects of cytokine inhibition.

J. Sasaki, S. Fujishima, H. Iwamura, K. Wakitani, S. Aiso, and N. Aikawa (2003)
Am J Physiol Lung Cell Mol Physiol 284, L270-L278
 |  Abstract »  |  Full Text »  |  PDF »

Restraint of Proinflammatory Cytokine Biosynthesis by Mitogen-Activated Protein Kinase Phosphatase-1 in Lipopolysaccharide-Stimulated Macrophages.

P. Chen, J. Li, J. Barnes, G. C. Kokkonen, J. C. Lee, and Y. Liu (2002)
J. Immunol. 169, 6408-6416
 |  Abstract »  |  Full Text »  |  PDF »

Post-transcriptional regulation of TNF-{alpha} during in vitro differentiation of human monocytes/macrophages in primary culture.

S. MacKenzie, N. Fernandez-Troy, and E. Espel (2002)
J. Leukoc. Biol. 71, 1026-1032
 |  Abstract »  |  Full Text »  |  PDF »

Luteolin Reduces Lipopolysaccharide-induced Lethal Toxicity and Expression of Proinflammatory Molecules in Mice.

A. KOTANIDOU, A. XAGORARI, E. BAGLI, P. KITSANTA, T. FOTSIS, A. PAPAPETROPOULOS, and C. ROUSSOS (2002)
Am. J. Respir. Crit. Care Med. 165, 818-823
 |  Abstract »  |  Full Text »  |  PDF »

A High Affinity HSF-1 Binding Site in the 5'-Untranslated Region of the Murine Tumor Necrosis Factor-alpha Gene Is a Transcriptional Repressor.

I. S. Singh, J.-R. He, S. Calderwood, and J. D. Hasday (2002)
J. Biol. Chem. 277, 4981-4988
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Modulation of Liver Annexin 1 Expression during Experimental Endotoxemia.

C. de Coupade, M. N. Ajuebor, F. Russo-Marie, M. Perretti, and E. Solito (2001)
Am. J. Pathol. 159, 1435-1443
 |  Abstract »  |  Full Text »

Invited review: Bacterial lipopolysaccharides and innate immunity.

C. Alexander and E. Th. Rietschel (2001)
Innate Immunity 7, 167-202
 |  Abstract »  |  PDF »

Dexamethasone Inhibits Tumor Necrosis Factor-{{alpha}}-Induced Apoptosis and Interleukin-1{beta} Release in Human Subcutaneous Adipocytes and Preadipocytes.

H. H. Zhang, S. Kumar, A. H. Barnett, and M. C. Eggo (2001)
J. Clin. Endocrinol. Metab. 86, 2817-2825
 |  Abstract »  |  Full Text »  |  PDF »

Glucocorticoid-mediated repression of inflammatory cytokine production in fibroblast-like rheumatoid synoviocytes is independent of nuclear factor-{{kappa}}B activation induced by tumour necrosis factor {{alpha}}.

C. W. Han, J. H. Choi, J. M. Kim, W. Y. Kim, K. Y. Lee, and G. T. Oh (2001)
Rheumatology 40, 267-273
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of dexamethasone-mediated interleukin-8 gene suppression in cultured airway epithelial cells.

M. M.-J. Chang, M. Juarez, D. M. Hyde, and R. Wu (2001)
Am J Physiol Lung Cell Mol Physiol 280, L107-L115
 |  Abstract »  |  Full Text »  |  PDF »

Anti-Inflammatory Effects of Ergotamine in Steers.

N. M. Filipov, F. N. Thompson, J. A. Stuedemann, T. H. Elsasser, S. Kahl, L. H. Stanker, C. R. Young, D. L. Dawe, and C. K. Smith (2000)
Experimental Biology and Medicine 225, 136-142
 |  Abstract »  |  Full Text »

Differential Host Inflammatory Responses to Viable Versus Antibiotic-Killed Bacteria in Experimental Microbial Sepsis.

R. Silverstein, J. G. Wood, Q. Xue, M. Norimatsu, D. L. Horn, and D. C. Morrison (2000)
Infect. Immun. 68, 2301-2308
 |  Abstract »  |  Full Text »  |  PDF »

PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene.

M. Rehli, A. Poltorak, L. Schwarzfischer, S. W. Krause, R. Andreesen, and B. Beutler (2000)
J. Biol. Chem. 275, 9773-9781
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Tumor Necrosis Factor-alpha Transcription in Macrophages Exposed to Febrile Range Temperature. A POSSIBLE ROLE FOR HEAT SHOCK FACTOR-1 AS A NEGATIVE TRANSCRIPTIONAL REGULATOR.

I. S. Singh, R. M. Viscardi, I. Kalvakolanu, S. Calderwood, and J. D. Hasday (2000)
J. Biol. Chem. 275, 9841-9848
 |  Abstract »  |  Full Text »  |  PDF »

The role of tumor necrosis factor in the pathophysiology of heart failure.

A. M. Feldman, A. Combes, D. Wagner, T. Kadakomi, T. Kubota, Y. You Li, and C. McTiernan (2000)
J. Am. Coll. Cardiol. 35, 537-544
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory mediators in human renal dysplasia.

C. M. Cale, N. J. Klein, P. J. D. Winyard, and A. S. Woolf (2000)
Nephrol. Dial. Transplant. 15, 173-183
 |  Abstract »  |  Full Text »  |  PDF »

Inosine Inhibits Inflammatory Cytokine Production by a Posttranscriptional Mechanism and Protects Against Endotoxin-Induced Shock.

G. Hasko, D. G. Kuhel, Z. H. Nemeth, J. G. Mabley, R. F. Stachlewitz, L. Virag, Z. Lohinai, G. J. Southan, A. L. Salzman, and C. Szabo (2000)
J. Immunol. 164, 1013-1019
 |  Abstract »  |  Full Text »  |  PDF »

fMet-Leu-Phe Stimulates Proinflammatory Cytokine Gene Expression in Human Peripheral Blood Monocytes: The Role of Phosphatidylinositol 3-Kinase.

Z. K. Pan, L.-Y. Chen, C. G. Cochrane, and B. L. Zuraw (2000)
J. Immunol. 164, 404-411
 |  Abstract »  |  Full Text »  |  PDF »

Antiinflammatory Effects of Glucocorticoids in Brain Cells, Independent of NF-{kappa}B.

E. Bourke and P. N. Moynagh (1999)
J. Immunol. 163, 2113-2119
 |  Abstract »  |  Full Text »  |  PDF »

HMG-1 as a Late Mediator of Endotoxin Lethality in Mice.

H. Wang, O. Bloom, M. Zhang, J. M. Vishnubhakat, M. Ombrellino, J. Che, A. Frazier, H. Yang, S. Ivanova, L. Borovikova, et al. (1999)
Science 285, 248-251
 |  Abstract »  |  Full Text »

Early-Onset Inflammatory Responses In Vivo to Adenoviral Vectors in the Presence or Absence of Lipopolysaccharide-Induced Inflammation.

P. S. Thorne, P. B. McCray Jr., T. S. Howe, and M. A. O'Neill (1999)
Am. J. Respir. Cell Mol. Biol. 20, 1155-1164
 |  Abstract »  |  Full Text »

Immunoglobulin G Fc-receptor (Fc{gamma}R) IIA and IIIB polymorphisms related to disability in MS.

K.-M. Myhr, G. Raknes, H. Nyland, and C. Vedeler (1999)
Neurology 52, 1771
 |  Abstract »  |  Full Text »  |  PDF »

Glucocorticoids Affect Human Dendritic Cell Differentiation and Maturation.

L. Piemonti, P. Monti, P. Allavena, M. Sironi, L. Soldini, B. E. Leone, C. Socci, and V. Di Carlo (1999)
J. Immunol. 162, 6473-6481
 |  Abstract »  |  Full Text »  |  PDF »

Lipopolysaccharide-induced Tumor Necrosis Factor-{alpha} Promoter Activity Is Inhibitor of Nuclear Factor-{kappa}B Kinase-dependent.

J. L. Swantek, L. Christerson, and M. H. Cobb (1999)
J. Biol. Chem. 274, 11667-11671
 |  Abstract »  |  Full Text »  |  PDF »

A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor alpha  gene expression: Molecular cloning, sequencing, characterization, and chromosomal assignment.

F. Myokai, S. Takashiba, R. Lebo, and S. Amar (1999)
PNAS 96, 4518-4523
 |  Abstract »  |  Full Text »  |  PDF »

Prevention by Methylprednisolone of Increased Circulating Tumor Necrosis Factor-{alpha} Levels and Lung Injury Associated with Systemic Inflammatory Response Syndrome due to Intraperitoneal Hyperthermia.

M. Sumida, H. Inaba, E. Isawa, S. Fujimoto, T. Satoh, and M. Kawamata (1999)
Anesth. Analg. 88, 771
 |  Abstract »  |  Full Text »  |  PDF »

Paradoxical Preservation of a Lipopolysaccharide Response in C3H/HeJ Macrophages: Induction of Matrix Metalloproteinase-9.

F.-y. Jin, C. F. Nathan, and A. Ding (1999)
J. Immunol. 162, 3596-3600
 |  Abstract »  |  Full Text »  |  PDF »

IL-18-deficient mice are resistant to endotoxin-induced liver injury but highly susceptible to endotoxin shock.

Y. Sakao, K. Takeda, H. Tsutsui, T. Kaisho, F. Nomura, H. Okamura, K. Nakanishi, and S. Akira (1999)
Int. Immunol. 11, 471-480
 |  Abstract »  |  Full Text »  |  PDF »

Role of endotoxin in intestinal reperfusion-induced expression of E-selectin.

P. Bauer, J. M. Russell, and D. N. Granger (1999)
Am J Physiol Gastrointest Liver Physiol 276, G479-G484
 |  Abstract »  |  Full Text »  |  PDF »

Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate Cyclase-Activation Polypeptide (PACAP) Protect Mice from Lethal Endotoxemia Through the Inhibition of TNF-{alpha} and IL-6.

M. Delgado, C. Martinez, D. Pozo, J. R. Calvo, J. Leceta, D. Ganea, and R. P. Gomariz (1999)
J. Immunol. 162, 1200-1205
 |  Abstract »  |  Full Text »  |  PDF »

Down-regulation of Human Granzyme B Expression by Glucocorticoids. DEXAMETHASONE INHIBITS BINDING TO THE Ikaros AND AP-1 REGULATORY ELEMENTS OF THE GRANZYME B PROMOTER.

A. Wargnier, C. Lafaurie, S. Legros-Maida, J.-F. Bourge, F. Sigaux, M. Sasportes, and P. Paul (1998)
J. Biol. Chem. 273, 35326-35331
 |  Abstract »  |  Full Text »  |  PDF »

Chronic Interstitial Lung Disease.

B. C. Hilman (1998)
Clinical Pediatrics 37, 701-702
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Intestinal Secretory Factor Released by Macrophages Stimulated with Clostridium difficile Toxin A: Role of Interleukin 1beta.

M. F. G. Rocha, A. M. Soares, C. A. Flores, T. S. Steiner, D. M. Lyerly, R. L. Guerrant, R. A. Ribeiro, and A. A. M. Lima (1998)
Infect. Immun. 66, 4910-4916
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Mn SOD in human monocytes without inflammatory cytokine production by a mutant endotoxin.

L. Tian, J. E. White, H.-Y. Lin, V. S. Haran, J. Sacco, G. Chikkappa, F. B. Davis, P. J. Davis, and M.-F. Tsan (1998)
Am J Physiol Cell Physiol 275, C740-C747
 |  Abstract »  |  Full Text »  |  PDF »

IL-4-Producing NK1.1+ T Cells Are Resistant to Glucocorticoid-Induced Apoptosis: Implications for the Th1/Th2 Balance.

K. Tamada, M. Harada, K. Abe, T. Li, and K. Nomoto (1998)
J. Immunol. 161, 1239-1247
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Receptor (TCR) Engagement Leads to Activation-induced Splicing of  Tumor Necrosis Factor (TNF) Nuclear Pre-mRNA.

Y. Yang, J.-F. Chang, J. R. Parnes, and C. Garrison Fathman (1998)
J. Exp. Med. 188, 247-254
 |  Abstract »  |  Full Text »  |  PDF »

Lipopolysaccharide-Related Stimuli Induce Expression of the Secretory Leukocyte Protease Inhibitor, a Macrophage-Derived Lipopolysaccharide Inhibitor.

F. Jin, C. F. Nathan, D. Radzioch, and A. Ding (1998)
Infect. Immun. 66, 2447-2452
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo and in Vitro Evidence for the Involvement of Tumor Necrosis Factor-{alpha} in the Induction of Leptin by Lipopolysaccharide.

B. N. Finck, K. W. Kelley, R. Dantzer, and R. W. Johnson (1998)
Endocrinology 139, 2278-2283
 |  Abstract »  |  Full Text »  |  PDF »

Revisiting the Role of Tumor Necrosis Factor {alpha} and the Response to Surgical Injury and Inflammation.

R. Ksontini, S. L. D. MacKay, and L. L. Moldawer (1998)
Arch Surg 133, 558-567
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Bruton's Tyrosine Kinase in Fcepsilon RI-dependent Mast Cell Degranulation and Cytokine Production.

D. Hata, Y. Kawakami, N. Inagaki, C. S. Lantz, T. Kitamura, W. N. Khan, M. Maeda-Yamamoto, T. Miura, W. Han, S. E. Hartman, et al. (1998)
J. Exp. Med. 187, 1235-1247
 |  Abstract »  |  Full Text »  |  PDF »

Cardiac Failure in Transgenic Mice With Myocardial Expression of Tumor Necrosis Factor-{alpha}.

D. Bryant, L. Becker, J. Richardson, J. Shelton, F. Franco, R. Peshock, M. Thompson, and B. Giroir (1998)
Circulation 97, 1375-1381
 |  Abstract »  |  Full Text »  |  PDF »

Corticosteroids Enhance the Capacity of Macrophages to Induce Th2 Cytokine Synthesis in CD4+ Lymphocytes by Inhibiting IL-12 Production.

R. H. DeKruyff, Y. Fang, and D. T. Umetsu (1998)
J. Immunol. 160, 2231-2237
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Monocyte IL-10 Synthesis by Endogenous IL-1 and TNF-{alpha}: Role of the p38 and p42/44 Mitogen-Activated Protein Kinases.

A. D. Foey, S. L. Parry, L. M. Williams, M. Feldmann, B. M. J. Foxwell, and F. M. Brennan (1998)
J. Immunol. 160, 920-928
 |  Abstract »  |  Full Text »  |  PDF »

Relative Contribution of Transcription and Translation to the Induction of Tumor Necrosis Factor-alpha by Lipopolysaccharide.

T. Raabe, M. Bukrinsky, and R. A. Currie (1998)
J. Biol. Chem. 273, 974-980
 |  Abstract »  |  Full Text »  |  PDF »

Relationship between plasma NOx and cardiac and vascular dysfunction after LPS injection in anesthetized dogs.

P. R. Forfia, X. Zhang, F. Ochoa, M. Ochoa, X. Xu, R. Bernstein, P. B. Sehgal, N. R. Ferreri, and T. H. Hintze (1998)
Am J Physiol Heart Circ Physiol 274, H193-H201
 |  Abstract »  |  Full Text »  |  PDF »

Effect of inflammatory and antiinflammatory stimuli on acyloxyacyl hydrolase gene expression and enzymatic activity in murine macrophages.

M.J. Cody, C.A. Salkowski, B.E. Henricson, G.R. Detore, R.S. Munford, and S.N. Vogel (1997)
Innate Immunity 4, 371-379
 |  Abstract »  |  PDF »

The Role of 3' Poly(A) Tail Metabolism in Tumor Necrosis Factor-alpha Regulation.

E. K. Crawford, J. E. Ensor, I. Kalvakolanu, and J. D. Hasday (1997)
J. Biol. Chem. 272, 21120-21127
 |  Abstract »  |  Full Text »  |  PDF »

Flanking Sequences for the Human Intercellular Adhesion Molecule-1 NF-kappa B Response Element Are Necessary for Tumor Necrosis Factor alpha -Induced Gene Expression.

L. L. L. Paxton, L.-J. Li, V. Secor, J. L. Duff, S. M. Naik, N. Shibagaki, and S. W. Caughman (1997)
J. Biol. Chem. 272, 15928-15935
 |  Abstract »  |  Full Text »  |  PDF »

Fundamental differences during Gram-positive versus Gram-negative sepsis become apparent during bacterial challenge of D-galactosamine-treated mice.

R. Silverstein, M. Norimatsu, and D.C. Morrison (1997)
Innate Immunity 4, 173-181
 |  Abstract »  |  PDF »

Long-Term Intracerebroventricular Infusion of Corticotropin-Releasing Hormone Alters Neuroendocrine, Neurochemical, Autonomic, Behavioral, and Cytokine Responses to a Systemic Inflammatory Challenge.

A. C. E. Linthorst, C. Flachskamm, S. J. Hopkins, M. E. Hoadley, MartaS. Labeur, F. Holsboer, and J. M. H. M. Reul (1997)
J. Neurosci. 17, 4448-4460
 |  Abstract »  |  Full Text »  |  PDF »

Spermine Inhibits Proinflammatory Cytokine Synthesis in Human Mononuclear Cells: A Counterregulatory Mechanism that Restrains the Immune Response.

M. Zhang, T. Caragine, H. Wang, P. S. Cohen, G. Botchkina, K. Soda, M. Bianchi, P. Ulrich, A. Cerami, B. Sherry, et al. (1997)
J. Exp. Med. 185, 1759-1768
 |  Abstract »  |  Full Text »  |  PDF »

Exhalation of gaseous nitric oxide by rats in response to endotoxin and its absorption by the lungs.

J. T. Stitt, A. B. Dubois, J. S. Douglas, and S. G. Shimada (1997)
J Appl Physiol 82, 305-316
 |  Abstract »  |  Full Text »  |  PDF »

Chemokine Expression in Human Oral Keratinocyte Cell Lines and Keratinized Mucosa.

M. Bickel, S.M. Nothen, K. Freiburghaus, and D. Shire (1996)
Journal of Dental Research 75, 1827-1834
 |  Abstract »  |  PDF »

Tumor Necrosis Factor and the Jarisch-Herxheimer Reaction.

B. Beutler and R. S. Munford (1996)
N. Engl. J. Med. 335, 346-348
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Mechanisms of Suppression of Inducible Nitric-oxide Synthase (iNOS) Expression in Interferon (IFN)-gamma -stimulated RAW 264.7 Cells by Dexamethasone. EVIDENCE FOR GLUCOCORTICOID-INDUCED DEGRADATION OF iNOS PROTEIN BY CALPAIN AS A KEY STEP IN POST-TRANSCRIPTIONAL REGULATION.

G. Walker, J. Pfeilschifter, and D. Kunz (1996)
J. Biol. Chem. 272, 16679-16687
 |  Abstract »  |  Full Text »  |  PDF »

Glucocorticoid-mediated Gene Suppression of Rat Cytokine-induced Neutrophil Chemoattractant CINC/gro, a Member of the Interleukin-8 Family, through Impairment of NF-kappaB Activation.

T. Ohtsuka, A. Kubota, T. Hirano, K. Watanabe, H. Yoshida, M. Tsurufuji, Y. Iizuka, K. Konishi, and S. Tsurufuji (1996)
J. Biol. Chem. 271, 1651-1659
 |  Abstract »  |  Full Text »  |  PDF »

Role of Transcriptional Activation of IkappaBalpha in Mediation of Immunosuppression by Glucocorticoi ds.

R. I. Scheinman, P. C. Cogswell, A. K. Lofquist, and A. S. Baldwin Jr. (1995)
Science 270, 283-286
 |  Abstract »  |  PDF »

Immunosuppression by Glucocorticoids: Inhibition of NF-kappaB Activity Through Induction of IkappaB Sy nthesis.

N. Auphan, J. A. DiDonato, C. Rosette, A. Helmberg, and M. Karin (1995)
Science 270, 286-290
 |  Abstract »  |  PDF »

Lipopolysaccharide is required for the lethal effects of enterotoxin B after D-galactosamine sensitization.

S.K. Chapes and A.A. Beharka (1995)
Innate Immunity 2, 263-271
 |  Abstract »  |  PDF »

Regulation of the Human TNF Promoter by the Transcription Factor Ets.

B. Krämer, K. Wiegmann, and M. Krönke (1995)
J. Biol. Chem. 270, 6577-6583
 |  Abstract »  |  Full Text »  |  PDF »

A Region of Human CD14 Required for Lipopolysaccharide Binding.

S. Viriyakosol and T. N. Kirkland (1995)
J. Biol. Chem. 270, 361-368
 |  Abstract »  |  Full Text »  |  PDF »

Glucocorticoid Receptor Blockade Reverses Postinjury Macrophage Suppression.

A. C. Cech, J. Shou, H. Gallagher, and J. M. Daly (1994)
Arch Surg 129, 1227-1232
 |  Abstract »  |  PDF »

Augmented Tumor Necrosis Factor Response to Lipopolysaccharide After Thermal Injury Is Regulated Posttranscriptionally.

J. P. Minei, J. G. Williams, S. J. Hill, K. McIntyre, and P. E. Bankey (1994)
Arch Surg 129, 1198-1203
 |  Abstract »  |  PDF »

Inhibition of Splenic Macrophage Tumor Necrosis Factor {alpha} Secretion In Vivo by Antilipopolysaccharide Monoclonal Antibodies.

R. J. Battafarano, R. S. Burd, K. M. Kurrelmeyer, C. A. Ratz, and D. L. Dunn (1994)
Arch Surg 129, 179-186
 |  Abstract »  |  PDF »

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.

G. Hotamisligil, N. Shargill, and B. Spiegelman (1993)
Science 259, 87-91
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Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice..

J Cheng, K Turksen, Q C Yu, H Schreiber, M Teng, and E Fuchs (1992)
Genes & Dev. 6, 1444-1456
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Effect of Combined Cortisol-Endotoxin Administration on Peripheral Blood Leukocyte Counts and Phenotype in Cortisol-Endotoxin.

S. E. Calvano, A. E. Barber, A. S. Hawes, H. F. de Riesthal, S. M. Coyle, and S. F. Lowry (1992)
Arch Surg 127, 181-186
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Does Endotoxin Tolerance Prevent the Release of Inflammatory Monokines (Interleukin 1, Interleukin 6, or Tumor Necrosis Factor) During Sepsis?.

A. Ayala, J. M. Kisala, J. A. Felt, M. M. Perrin, and I. H. Chaudry (1992)
Arch Surg 127, 191-197
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The Pathogenesis of Sepsis.

R. C. Bone (1991)
Ann Intern Med 115, 457-469
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Intravascular Plastic Catheters: How They Potentiate Tumor Necrosis Factor Release and Exacerbate Complications Associated With Sepsis.

L. F. Martin, T. C. Vary, P. K. Davis, B. L. Munger, J. C. Lynch, S. Spangler, and D. G. Remick (1991)
Arch Surg 126, 1087-1093
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Hormonal and Metabolic Response to Operative Stress in the Neonate.

D. J. Schmeling and A. G. Coran (1991)
JPEN J Parenter Enteral Nutr 15, 215-238
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Cerebrospinal Fluid Prostaglandins, Interleukin 1{beta}, and Tumor Necrosis Factor in Bacterial Meningitis: Clinical and Laboratory Correlations in Placebo-Treated and Dexamethasone-Treated Patients.

M. M. Mustafa, O. Ramilo, X. S. Llorens, K. D. Olsen, R. R. Magness, and G. H. McCracken Jr (1990)
Arch Pediatr Adolesc Med 144, 883-887
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Shared actions of endotoxin and taxol on TNF receptors and TNF release.

A. Ding, F Porteu, E Sanchez, and C. Nathan (1990)
Science 248, 370-372
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Bacterial Meningitis: Recent Advances in Pathophysiology and Treatment.

A. R. Tunkel, B. Wispelwey, and W. M. Scheld (1990)
Ann Intern Med 112, 610-623
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Sepsis, Signals, and Surgical Sequelae (A Hypothesis).

H. R. Michie and D. W. Wilmore (1990)
Arch Surg 125, 531-536
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Endotoxin Tolerance Is Associated With Reduced Secretion of Tumor Necrosis Factor.

L. Sanchez-Cantu, H. N. Rode, and N. V. Christou (1989)
Arch Surg 124, 1432-1436
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Translational blockade imposed by cytokine-derived UA-rich sequences.

V Kruys, O Marinx, G Shaw, J Deschamps, and G Huez (1989)
Science 245, 852-855
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Antisense RNA directed against the 3' noncoding region prevents dormant mRNA activation in mouse oocytes.

S Strickland, J Huarte, D Belin, A Vassalli, R. Rickles, and J. Vassalli (1988)
Science 241, 680-684
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Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling.

H Vlassara, M Brownlee, K. Manogue, C. Dinarello, and A Pasagian (1988)
Science 240, 1546-1548
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Manifestations of Sepsis.

R. L. Harris, D. M. Musher, K. Bloom, J. Gathe, L. Rice, B. Sugarman, T. W. Williams Jr, and E. J. Young (1987)
Arch Intern Med 147, 1895-1906
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Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria.

G. Grau, L. Fajardo, P. Piguet, B Allet, P. Lambert, and P Vassalli (1987)
Science 237, 1210-1212
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