Science 23 May 1986: Vol. 232. no. 4753, pp. 1004 - 1007 DOI: 10.1126/science.2422758

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Articles

Progesterone Receptor A (PRA) and PRB-Independent Effects of Progesterone on Gonadotropin-Releasing Hormone Release.

N. Sleiter, Y. Pang, C. Park, T. H. Horton, J. Dong, P. Thomas, and J. E. Levine (2009)
Endocrinology 150, 3833-3844
 |  Abstract »  |  Full Text »  |  PDF »

Changes in Expression and Function of Extrasynaptic GABAA Receptors in the Rat Hippocampus during Pregnancy and after Delivery.

E. Sanna, M. C. Mostallino, L. Murru, M. Carta, G. Talani, S. Zucca, M. L. Mura, E. Maciocco, and G. Biggio (2009)
J. Neurosci. 29, 1755-1765
 |  Abstract »  |  Full Text »  |  PDF »

Estradiol Modulates Functional Brain Organization during the Menstrual Cycle: An Analysis of Interhemispheric Inhibition.

S. Weis, M. Hausmann, B. Stoffers, R. Vohn, T. Kellermann, and W. Sturm (2008)
J. Neurosci. 28, 13401-13410
 |  Abstract »  |  Full Text »  |  PDF »

Tryptophan Mutations at Azi-Etomidate Photo-Incorporation Sites on {alpha}1 or {beta}2 Subunits Enhance GABAA Receptor Gating and Reduce Etomidate Modulation.

D. Stewart, R. Desai, Q. Cheng, A. Liu, and S. A. Forman (2008)
Mol. Pharmacol. 74, 1687-1695
 |  Abstract »  |  Full Text »  |  PDF »

Antipsychotic Drugs: Comparison in Animal Models of Efficacy, Neurotransmitter Regulation, and Neuroprotection.

J. A. Lieberman, F. P. Bymaster, H. Y. Meltzer, A. Y. Deutch, G. E. Duncan, C. E. Marx, J. R. Aprille, D. S. Dwyer, X.-M. Li, S. P. Mahadik, et al. (2008)
Pharmacol. Rev. 60, 358-403
 |  Abstract »  |  Full Text »  |  PDF »

Emerging Roles for Neurosteroids in Sexual Behavior and Function.

S. R. King (2008)
J Androl 29, 524-533
 |  Abstract »  |  Full Text »  |  PDF »

Cortisol Inhibits Neuroplasticity Induction in Human Motor Cortex.

M. V. Sale, M. C. Ridding, and M. A. Nordstrom (2008)
J. Neurosci. 28, 8285-8293
 |  Abstract »  |  Full Text »  |  PDF »

Antidepressant effect and changes of GABAA receptor {gamma}2 subunit mRNA after hippocampal administration of allopregnanolone in rats.

M. Nin, F. Salles, L. Azeredo, A. Frazon, R. Gomez, and H. Barros (2008)
J Psychopharmacol 22, 477-485
 |  Abstract »  |  PDF »

Neuroactive Steroid Stereospecificity of Ethanol-Like Discriminative Stimulus Effects in Monkeys.

K. A. Grant, C. M. Helms, L. S. M. Rogers, and R. H. Purdy (2008)
J. Pharmacol. Exp. Ther. 326, 354-361
 |  Abstract »  |  Full Text »  |  PDF »

How Progesterone Impairs Memory for Biologically Salient Stimuli in Healthy Young Women.

G. van Wingen, F. van Broekhoven, R. J. Verkes, K. M. Petersson, T. Backstrom, J. Buitelaar, and G. Fernandez (2007)
J. Neurosci. 27, 11416-11423
 |  Abstract »  |  Full Text »  |  PDF »

Novel Perspectives for Progesterone in Hormone Replacement Therapy, with Special Reference to the Nervous System.

M. Schumacher, R. Guennoun, A. Ghoumari, C. Massaad, F. Robert, M. El-Etr, Y. Akwa, K. Rajkowski, and E.-E. Baulieu (2007)
Endocr. Rev. 28, 387-439
 |  Abstract »  |  Full Text »  |  PDF »

Role of Microsomal Retinol/Sterol Dehydrogenase-Like Short-Chain Dehydrogenases/Reductases in the Oxidation and Epimerization of 3{alpha}-Hydroxysteroids in Human Tissues.

O. V. Belyaeva, S. V. Chetyrkin, A. L. Clark, N. V. Kostereva, K. S. SantaCruz, B. M. Chronwall, and N. Y. Kedishvili (2007)
Endocrinology 148, 2148-2156
 |  Abstract »  |  Full Text »  |  PDF »

Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus.

Y. B. Saalmann, I. G. Morgan, and M. B. Calford (2006)
J Neurophysiol 96, 3064-3073
 |  Abstract »  |  Full Text »  |  PDF »

Progesterone metabolites in breast cancer..

J. P Wiebe (2006)
Endocr. Relat. Cancer 13, 717-738
 |  Abstract »  |  Full Text »  |  PDF »

Cell-surface expression, progestin binding, and rapid nongenomic signaling of zebrafish membrane progestin receptors {alpha} and {beta} in transfected cells..

R. Hanna, Y. Pang, P. Thomas, and Y. Zhu (2006)
J. Endocrinol. 190, 247-260
 |  Abstract »  |  Full Text »  |  PDF »

Neurosteroid modulation of respiratory rhythm in rats during the perinatal period.

J. Ren and J. J. Greer (2006)
J. Physiol. 574, 535-546
 |  Abstract »  |  Full Text »  |  PDF »

Endocrine Disrupting Chemical Atrazine Causes Degranulation through Gq/11 Protein-Coupled Neurosteroid Receptor in Mast Cells.

K. Mizota and H. Ueda (2006)
Toxicol. Sci. 90, 362-368
 |  Abstract »  |  Full Text »  |  PDF »

Injury Elicited Increase in Spinal Cord Neurosteroid Content Analyzed by Gas Chromatography Mass Spectrometry.

F. Labombarda, A. Pianos, P. Liere, B. Eychenne, S. Gonzalez, A. Cambourg, A. F. De Nicola, M. Schumacher, and R. Guennoun (2006)
Endocrinology 147, 1847-1859
 |  Abstract »  |  Full Text »  |  PDF »

Menstrual disorders in women with epilepsy.

A. G. Herzog (2006)
Neurology 66, S23-S28
 |  Abstract »  |  Full Text »

Apparent receptor-mediated activation of Ca2+-dependent conductive Cl- transport by shark-derived polyaminosterols.

M. N. Chernova, D. H. Vandorpe, J. S. Clark, J. I. Williams, M. A. Zasloff, L. Jiang, and S. L. Alper (2005)
Am J Physiol Regulatory Integrative Comp Physiol 289, R1644-R1658
 |  Abstract »  |  Full Text »  |  PDF »

Orbitofrontal cortex activity related to emotional processing changes across the menstrual cycle.

X. Protopopescu, H. Pan, M. Altemus, O. Tuescher, M. Polanecsky, B. McEwen, D. Silbersweig, and E. Stern (2005)
PNAS 102, 16060-16065
 |  Abstract »  |  Full Text »  |  PDF »

Bidirectional Modulation of Hippocampal Long-Term Potentiation under Stress and No-Stress Conditions in Basolateral Amygdala-Lesioned and Intact Rats.

V. Korz and J. U. Frey (2005)
J. Neurosci. 25, 7393-7400
 |  Abstract »  |  Full Text »  |  PDF »

Neurosteroid administration and withdrawal alter GABAA receptor kinetics in CA1 hippocampus of female rats.

S. S Smith and Q. H. Gong (2005)
J. Physiol. 564, 421-436
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Lordosis by Cyclic 3',5'-Guanosine Monophosphate, Progesterone, and Its 5{alpha}-Reduced Metabolites Involves Mitogen-Activated Protein Kinase.

O. Gonzalez-Flores, J. Shu, I. Camacho-Arroyo, and A. M. Etgen (2004)
Endocrinology 145, 5560-5567
 |  Abstract »  |  Full Text »  |  PDF »

Competitive Inhibition of the Capsaicin Receptor-Mediated Current by Dehydroepiandrosterone in Rat Dorsal Root Ganglion Neurons.

S.-C. Chen, T.-J. Chang, and F.-S. Wu (2004)
J. Pharmacol. Exp. Ther. 311, 529-536
 |  Abstract »  |  Full Text »  |  PDF »

Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion.

P. N Nguyen, E. B Yan, M. Castillo-Melendez, D. W Walker, and J. J Hirst (2004)
J. Physiol. 560, 593-602
 |  Abstract »  |  Full Text »  |  PDF »

Effects on fear reactivity in XO mice are due to haploinsufficiency of a non-PAR X gene: implications for emotional function in Turner's syndrome.

A. R. Isles, W. Davies, D. Burrmann, P. S. Burgoyne, and L. S. Wilkinson (2004)
Hum. Mol. Genet. 13, 1849-1855
 |  Abstract »  |  Full Text »  |  PDF »

Brain Steroidogenesis Mediates Ethanol Modulation of GABAA Receptor Activity in Rat Hippocampus.

E. Sanna, G. Talani, F. Busonero, M. G. Pisu, R. H. Purdy, M. Serra, and G. Biggio (2004)
J. Neurosci. 24, 6521-6530
 |  Abstract »  |  Full Text »  |  PDF »

Insight into the Mechanism of Action of Neuroactive Steroids.

K. D. W. Morris and J. Amin (2004)
Mol. Pharmacol. 66, 56-69
 |  Abstract »  |  Full Text »  |  PDF »

Neuroactive steroids have multiple actions to potentiate GABAA receptors.

G. Akk, J. R. Bracamontes, D. F. Covey, A. Evers, T. Dao, and J. H. Steinbach (2004)
J. Physiol. 558, 59-74
 |  Abstract »  |  Full Text »  |  PDF »

{beta}-naphthoflavone induction of CYP1A in brain of juvenile lake trout (Salvelinus namaycush Walbaum).

Y.-W. Chung-Davidson, C. B. Rees, H. Wu, S.-S. Yun, and W. Li (2004)
J. Exp. Biol. 207, 1533-1542
 |  Abstract »  |  Full Text »  |  PDF »

Presence of protein-bound unconjugated bile acids in the cytoplasmic fraction of rat brain.

N. Mano, T. Goto, M. Uchida, K. Nishimura, M. Ando, N. Kobayashi, and J. Goto (2004)
J. Lipid Res. 45, 295-300
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Regulation of P450scc Gene Expression in the Embryonic Rodent Nervous System.

F. Hammer, N. A. Compagnone, J.-L. Vigne, S. R. Bair, and S. H. Mellon (2004)
Endocrinology 145, 901-912
 |  Abstract »  |  Full Text »  |  PDF »

Neuroactive Steroid Interactions with Voltage-Dependent Anion Channels: Lack of Relationship to GABAA Receptor Modulation and Anesthesia.

R. Darbandi-Tonkabon, B. D. Manion, W. R. Hastings, W. J. Craigen, G. Akk, J. R. Bracamontes, Y. He, T. V. Sheiko, J. H. Steinbach, S. J. Mennerick, et al. (2004)
J. Pharmacol. Exp. Ther. 308, 502-511
 |  Abstract »  |  Full Text »  |  PDF »

Neurosteroids Alter {gamma}-Aminobutyric Acid Postsynaptic Currents in Gonadotropin-Releasing Hormone Neurons: A Possible Mechanism for Direct Steroidal Control.

S. D. Sullivan and S. M. Moenter (2003)
Endocrinology 144, 4366-4375
 |  Abstract »  |  Full Text »  |  PDF »

Metabolic Regulation of Fertility through Presynaptic and Postsynaptic Signaling to Gonadotropin-Releasing Hormone Neurons.

S. D. Sullivan, R. A. DeFazio, and S. M. Moenter (2003)
J. Neurosci. 23, 8578-8585
 |  Abstract »  |  Full Text »  |  PDF »

Catamenial epilepsy: Pathophysiology, diagnosis, and management.

N. Foldvary-Schaefer and T. Falcone (2003)
Neurology 61, S2-15
 |  Abstract »  |  Full Text »

Nongenomic Steroid Action: Controversies, Questions, and Answers.

R. M. LOSEL, E. FALKENSTEIN, M. FEURING, A. SCHULTZ, H.-C. TILLMANN, K. ROSSOL-HASEROTH, and M. WEHLING (2003)
Physiol Rev 83, 965-1016
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Estrogen Plus Progestin on Global Cognitive Function in Postmenopausal Women: The Women's Health Initiative Memory Study: A Randomized Controlled Trial.

S. R. Rapp, M. A. Espeland, S. A. Shumaker, V. W. Henderson, R. L. Brunner, J. E. Manson, M. L. S. Gass, M. L. Stefanick, D. S. Lane, J. Hays, et al. (2003)
JAMA 289, 2663-2672
 |  Abstract »  |  Full Text »  |  PDF »

Menstrual Cycle-Dependent Neural Plasticity in the Adult Human Brain Is Hormone, Task, and Region Specific.

G. Fernandez, S. Weis, B. Stoffel-Wagner, I. Tendolkar, M. Reuber, S. Beyenburg, P. Klaver, J. Fell, A. de Greiff, J. Ruhlmann, et al. (2003)
J. Neurosci. 23, 3790-3795
 |  Abstract »  |  Full Text »  |  PDF »

Photoaffinity Labeling with a Neuroactive Steroid Analogue. 6-AZI-PREGNANOLONE LABELS VOLTAGE-DEPENDENT ANION CHANNEL-1 IN RAT BRAIN.

R. Darbandi-Tonkabon, W. R. Hastings, C.-M. Zeng, G. Akk, B. D. Manion, J. R. Bracamontes, J. H. Steinbach, S. J. Mennerick, D. F. Covey, and A. S. Evers (2003)
J. Biol. Chem. 278, 13196-13206
 |  Abstract »  |  Full Text »  |  PDF »

Neurosteroid Effects on GABAergic Synaptic Plasticity in Hippocampus.

F.-C. Hsu, R. Waldeck, D. S. Faber, and S. S. Smith (2003)
J Neurophysiol 89, 1929-1940
 |  Abstract »  |  Full Text »  |  PDF »

Perinatal Neurosteroid Levels Influence GABAergic Interneuron Localization in Adult Rat Prefrontal Cortex.

A. C. Grobin, E. J. Heenan, J. A. Lieberman, and A. L. Morrow (2003)
J. Neurosci. 23, 1832-1839
 |  Abstract »  |  Full Text »  |  PDF »

Induced Panic Attacks Shift {gamma}-Aminobutyric Acid Type A Receptor Modulatory Neuroactive Steroid Composition in Patients With Panic Disorder: Preliminary Results.

A. Strohle, E. Romeo, F. di Michele, A. Pasini, B. Hermann, G. Gajewsky, F. Holsboer, and R. Rupprecht (2003)
Arch Gen Psychiatry 60, 161-168
 |  Abstract »  |  Full Text »  |  PDF »

Progesterone Withdrawal Reduces Paired-Pulse Inhibition in Rat Hippocampus: Dependence on GABAA Receptor alpha 4 Subunit Upregulation.

F.-C. Hsu and S. S. Smith (2003)
J Neurophysiol 89, 186-198
 |  Abstract »  |  Full Text »  |  PDF »

Comparison of Effect of Ethanol on N-Methyl-D-aspartate- and GABA-Gated Currents from Acutely Dissociated Neurons: Absence of Regional Differences in Sensitivity to Ethanol.

H. E. Criswell, Z. Ming, B. L. Griffith, and G. R. Breese (2003)
J. Pharmacol. Exp. Ther. 304, 192-199
 |  Abstract »  |  Full Text »  |  PDF »

An Essential Component in Steroid Synthesis, the Steroidogenic Acute Regulatory Protein, Is Expressed in Discrete Regions of the Brain.

S. R. King, P. R. Manna, T. Ishii, P. J. Syapin, S. D. Ginsberg, K. Wilson, L. P. Walsh, K. L. Parker, D. M. Stocco, R. G. Smith, et al. (2002)
J. Neurosci. 22, 10613-10620
 |  Abstract »  |  Full Text »  |  PDF »

Allopregnanolone Activates GABAA Receptor/Cl- Channels in a Multiphasic Manner in Embryonic Rat Hippocampal Neurons.

Q.-Y. Liu, Y. H. Chang, A. E. Schaffner, S. V. Smith, and J. L. Barker (2002)
J Neurophysiol 88, 1147-1158
 |  Abstract »  |  Full Text »  |  PDF »

Cortical {gamma}-Aminobutyric Acid Levels Across the Menstrual Cycle in Healthy Women and Those With Premenstrual Dysphoric Disorder: A Proton Magnetic Resonance Spectroscopy Study.

C. N. Epperson, K. Haga, G. F. Mason, E. Sellers, R. Gueorguieva, W. Zhang, E. Weiss, D. L. Rothman, and J. H. Krystal (2002)
Arch Gen Psychiatry 59, 851-858
 |  Abstract »  |  Full Text »  |  PDF »

Acute Modulation of Aged Human Memory by Pharmacological Manipulation of Glucocorticoids.

S. J. Lupien, C. W. Wilkinson, S. Briere, N. M. K. Ng Ying Kin, M. J. Meaney, and N. P. V. Nair (2002)
J. Clin. Endocrinol. Metab. 87, 3798-3807
 |  Abstract »  |  Full Text »  |  PDF »

High Serum Allopregnanolone Levels in Girls with Precocious Puberty.

L. Iughetti, B. Predieri, L. Cobellis, S. Luisi, M. Luisi, S. Forese, F. Petraglia, and S. Bernasconi (2002)
J. Clin. Endocrinol. Metab. 87, 2262-2265
 |  Abstract »  |  Full Text »  |  PDF »

Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABAA Receptor Function and Seizure Susceptibility.

D. S. Reddy and M. A. Rogawski (2002)
J. Neurosci. 22, 3795-3805
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional regulation of the mouse steroid 5{alpha}-reductase type II gene by progesterone in brain.

D. Matsui, M. Sakari, T. Sato, A. Murayama, I. Takada, M. Kim, K.-i. Takeyama, and S. Kato (2002)
Nucleic Acids Res. 30, 1387-1393
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Neurosteroid Potentiation of Ternary GABAA Receptors Containing the delta Subunit.

K. M. Wohlfarth, M. T. Bianchi, and R. L. Macdonald (2002)
J. Neurosci. 22, 1541-1549
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Cytokines in the Depression of CYP1A Activity Using Cultured Astrocytes as an in Vitro Model of Inflammation in the Central Nervous System.

T. E. Nicholson and K. W. Renton (2002)
Drug Metab. Dispos. 30, 42-46
 |  Abstract »  |  Full Text »  |  PDF »

Structure of the Human 3alpha -Hydroxysteroid Dehydrogenase Type 3 in Complex with Testosterone and NADP at 1.25-A Resolution.

V. Nahoum, A. Gangloff, P. Legrand, D.-W. Zhu, L. Cantin, B. S. Zhorov, V. Luu-The, F. Labrie, R. Breton, and S.-X. Lin (2001)
J. Biol. Chem. 276, 42091-42098
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Uterine {{gamma}}-Aminobutyric AcidA Receptor Subunit Expression throughout Pregnancy.

E. Fujii and S. H. Mellon (2001)
Endocrinology 142, 1770-1777
 |  Abstract »  |  Full Text »

Evidence That Cyproterone Acetate Improves Psychological Symptoms and Enhances the Activity of the Dopaminergic System in Postmenopause.

A. M. Paoletti, S. Floris, M. Mannias, M. Orrù, D. Crippa, R. Orlandi, M. Del Zompo, and G. B. Melis (2001)
J. Clin. Endocrinol. Metab. 86, 608-612
 |  Abstract »  |  Full Text »

Human Types 1 and 3 3{{alpha}}-Hydroxysteroid Dehydrogenases: Differential Lability and Tissue Distribution.

I. Dufort, F. Labrie, and V. Luu-The (2001)
J. Clin. Endocrinol. Metab. 86, 841-846
 |  Abstract »  |  Full Text »

Heterogeneity of Hippocampal GABAA Receptors: Regulation by Corticosterone.

M. Orchinik, S. S. Carroll, Y.-H. Li, B. S. McEwen, and N. G. Weiland (2001)
J. Neurosci. 21, 330-339
 |  Abstract »  |  Full Text »  |  PDF »

Plasma Levels of Neuroactive Steroids Are Increased in Untreated Women With Anorexia Nervosa or Bulimia Nervosa.

P. Monteleone, M. Luisi, B. Colurcio, E. Casarosa, P. Monteleone, R. Ioime, A. R. Genazzani, and M. Maj (2001)
Psychosom Med 63, 62-68
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Actions of Steroid Hormones---A Focus on Rapid, Nongenomic Effects.

E. Falkenstein, H.-C. Tillmann, M. Christ, M. Feuring, and M. Wehling (2000)
Pharmacol. Rev. 52, 513-556
 |  Abstract »  |  Full Text »  |  PDF »

Estrogen Inhibition of Cystic Fibrosis Transmembrane Conductance Regulator-Mediated Chloride Secretion.

A. K. Singh, B. D. Schultz, J. A. Katzenellenbogen, E. M. Price, R. J. Bridges, and N. A. Bradbury (2000)
J. Pharmacol. Exp. Ther. 295, 195-204
 |  Abstract »  |  Full Text »

Dehydroepiandrosterone Sulfate Is Neuroprotective in a Reversible Spinal Cord Ischemia Model : Possible Involvement of GABAA Receptors Editorial Comment: Possible Involvement of GABAA Receptors.

P. A. Lapchak, D. F. Chapman, S. Y. Nunez, J. A. Zivin, and C. Y. Hsu (2000)
Stroke 31, 1953-1957
 |  Abstract »  |  Full Text »  |  PDF »

Novel Role for the Nuclear Phosphoprotein SET in Transcriptional Activation of P450c17 and Initiation of Neurosteroidogenesis.

N. A. Compagnone, P. Zhang, J.-L. Vigne, and S. H. Mellon (2000)
Mol. Endocrinol. 14, 875-888
 |  Abstract »  |  Full Text »

Enantioselectivity of Pregnanolone-Induced gamma -Aminobutyric AcidA Receptor Modulation and Anesthesia.

D. F. Covey, D. Nathan, M. Kalkbrenner, K. R. Nilsson, Y. Hu, C. F. Zorumski, and A. S. Evers (2000)
J. Pharmacol. Exp. Ther. 293, 1009-1016
 |  Abstract »  |  Full Text »

Allopregnanolone Synthesis in Cerebellar Granule Cells: Roles in Regulation of GABAA Receptor Expression and Function during Progesterone Treatment and Withdrawal.

P. Follesa, M. Serra, E. Cagetti, M. G. Pisu, S. Porta, S. Floris, F. Massa, E. Sanna, and G. Biggio (2000)
Mol. Pharmacol. 57, 1262-1270
 |  Abstract »  |  Full Text »

Estrogen-Astrocyte-Luteinizing Hormone-Releasing Hormone Signaling: A Rolefor Transforming Growth Factor-{beta}1.

C. D. Buchanan, V. B. Mahesh, and D. W. Brann (2000)
Biol Reprod 62, 1710-1721
 |  Abstract »  |  Full Text »

Neurosteroid Modulation of GABA IPSCs Is Phosphorylation Dependent.

A. Fancsik, D. M. Linn, and J. G. Tasker (2000)
J. Neurosci. 20, 3067-3075
 |  Abstract »  |  Full Text »  |  PDF »

Slow Death of Postnatal Hippocampal Neurons by GABAA Receptor Overactivation.

W. Xu, R. Cormier, T. Fu, D. F. Covey, K. E. Isenberg, C. F. Zorumski, and S. Mennerick (2000)
J. Neurosci. 20, 3147-3156
 |  Abstract »  |  Full Text »  |  PDF »

The 4-Pregnene and 5{{alpha}}-Pregnane Progesterone Metabolites Formed in Nontumorous and Tumorous Breast Tissue Have Opposite Effects on Breast Cell Proliferation and Adhesion.

J. P. Wiebe, D. Muzia, J. Hu, D. Szwajcer, S. A. Hill, and J. L. Seachrist (2000)
Cancer Res. 60, 936-943
 |  Abstract »  |  Full Text »

Effect of Ganaxolone in a Rodent Model of Cerebral Hematoma Editorial Comment.

P. Lyden, C. Shin, C. Jackson-Friedman, S. Hassid, A. Chong, and R. L. Macdonald (2000)
Stroke 31, 169-175
 |  Abstract »  |  Full Text »  |  PDF »

Interactive Role for Neurosteroids in Ethanol Enhancement of gamma -Aminobutyric Acid-Gated Currents from Dissociated Substantia Nigra Reticulata Neurons.

H. E. Criswell, T. J. McCown, Z. Ming, R. A. Mueller, and G. R. Breese (1999)
J. Pharmacol. Exp. Ther. 291, 1054-1059
 |  Abstract »  |  Full Text »

Enigma of the Peripheral Benzodiazepine Receptor.

M. Gavish, I. Bachman, R. Shoukrun, Y. Katz, L. Veenman, G. Weisinger, and A. Weizman (1999)
Pharmacol. Rev. 51, 629-650
 |  Abstract »  |  Full Text »  |  PDF »

Effects of a naturally occurring neurosteroid on GABAA IPSCs during development in rat hippocampal or cerebellar slices.

E. J Cooper, G. A R Johnston, and F. A Edwards (1999)
J. Physiol. 521, 437-449
 |  Abstract »  |  Full Text »  |  PDF »

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes.

L. D. Griffin and S. H. Mellon (1999)
PNAS 96, 13512-13517
 |  Abstract »  |  Full Text »  |  PDF »

Sex Differences in the Pentylenetetrazol-Like Stimulus Induced by Ethanol Withdrawal.

M. E. Jung, C. J. Wallis, M. B. Gatch, and H. Lal (1999)
J. Pharmacol. Exp. Ther. 291, 576-582
 |  Abstract »  |  Full Text »

Differential Modulation of the gamma -Aminobutyric Acid Type C Receptor by Neuroactive Steroids.

K. D. W. Morris, C. N. Moorefield, and J. Amin (1999)
Mol. Pharmacol. 56, 752-759
 |  Abstract »  |  Full Text »

Gonadal Steroids in the Treatment of Mood Disorders.

C. N. Epperson, K. L. Wisner, and B. Yamamoto (1999)
Psychosom Med 61, 676-697
 |  Abstract »  |  Full Text »  |  PDF »

Neurosteroid Modulation of Synaptic and GABA-Evoked Currents in Neurons From the Rat Medial Preoptic Nucleus.

D. Haage and S. Johansson (1999)
J Neurophysiol 82, 143-151
 |  Abstract »  |  Full Text »  |  PDF »

Psychoneuroendocrine Aspects of Temporolimbic Epilepsy: Part I. Brain, Reproductive Steroids, and Emotions.

A. G. Herzog (1999)
Psychosomatics 40, 95-101
 |  Abstract »  |  Full Text »

Psychoneuroendocrine Aspects of Temporolimbic Epilepsy: Part II: Epilepsy and Reproductive Steroids.

A. G. Herzog (1999)
Psychosomatics 40, 102-108
 |  Abstract »  |  Full Text »

Pregnenolone, Pregnenolone Sulfate, and Cytochrome P450 Side-Chain Cleavage Enzyme in the Amphibian Brain and Their Seasonal Changes.

M. Takase, K. Ukena, T. Yamazaki, S. Kominami, and K. Tsutsui (1999)
Endocrinology 140, 1936-1944
 |  Abstract »  |  Full Text »

Physical and Psychosocial Correlates of Hormone Replacement Therapy with Chronically Stressed Postmenopausal Women.

A. M. Steffen, L. W. Thompson, D. Gallagher-Thompson, and D. Koin (1999)
J Aging Health 11, 3-26
 |  Abstract »  |  PDF »

Expression and Activity of 3{beta}-Hydroxysteroid Dehydrogenase/{Delta}5-{Delta}4-Isomerase in the Rat Purkinje Neuron during Neonatal Life.

K. Ukena, C. Kohchi, and K. Tsutsui (1999)
Endocrinology 140, 805-813
 |  Abstract »  |  Full Text »

Finasteride, a 5alpha -Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice.

T. G. Kokate, M. K. Banks, T. Magee, S.-I. Yamaguchi, and M. A. Rogawski (1999)
J. Pharmacol. Exp. Ther. 288, 679-684
 |  Abstract »  |  Full Text »

Lack of Anticonvulsant Tolerance to the Neuroactive Steroid Pregnanolone in Mice.

T. G. Kokate, S.-I. Yamaguchi, L. K. Pannell, U. Rajamani, D. M. Carroll, A. B. Grossman, and M. A. Rogawski (1998)
J. Pharmacol. Exp. Ther. 287, 553-558
 |  Abstract »  |  Full Text »

Absence Seizures Decrease Steroid Modulation of t-[35S]Butylbicyclophosphorothionate Binding in Thalamic Relay Nuclei.

P. K. Banerjee, R. W. Olsen, N. J. K. Tillakaratne, S. Brailowsky, A. J. Tobin, and O. C. Snead III (1998)
J. Pharmacol. Exp. Ther. 287, 766-772
 |  Abstract »  |  Full Text »

Substituted 3beta -Phenylethynyl Derivatives of 3alpha -Hydroxy-5alpha -pregnan-20-one: Remarkably Potent Neuroactive Steroid Modulators of gamma -Aminobutyric AcidA Receptors.

J. E. Hawkinson, M. Acosta-Burruel, K. C. Yang, D. J. Hogenkamp, J.-S. Chen, N. C. Lan, J. A. Drewe, E. R. Whittemore, R. M. Woodward, R. B. Carter, et al. (1998)
J. Pharmacol. Exp. Ther. 287, 198-207
 |  Abstract »  |  Full Text »

Functional Antagonism of Gonadal Steroids at the 5-Hydroxytryptamine Type 3 Receptor.

C. H. R. Wetzel, B. Hermann, C. Behl, E. Pestel, G. Rammes, W. Zieglgänsberger, F. Holsboer, and R. Rupprecht (1998)
Mol. Endocrinol. 12, 1441-1451
 |  Abstract »  |  Full Text »

The negative feedback actions of progesterone on gonadotropinreleasing hormone secretion are transduced by the classical progesterone receptor.

D. C. Skinner, N. P. Evans, B. Delaleu, R. L. Goodman, P. Bouchard, and A. Caraty (1998)
PNAS 95, 10978-10983
 |  Abstract »  |  Full Text »  |  PDF »

Withdrawal from 3alpha -OH-5alpha -Pregnan-20-One Using a Pseudopregnancy Model Alters the Kinetics of Hippocampal GABAA-Gated Current and Increases the GABAA Receptor alpha 4 Subunit in Association with Increased Anxiety.

S. S. Smith, Q. H. Gong, X. Li, M. H. Moran, D. Bitran, C. A. Frye, and F.-C. Hsu (1998)
J. Neurosci. 18, 5275-5284
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Antidepressant Treatment on Neuroactive Steroids in Major Depression.

E. Romeo, A. Ströhle, G. Spalletta, F. d. Michele, B. Hermann, F. Holsboer, A. Pasini, and R. Rupprecht (1998)
Am J Psychiatry 155, 910-913
 |  Abstract »  |  Full Text »

Activation of Human Liver 3alpha -Hydroxysteroid Dehydrogenase by Clofibrate Derivatives.

K. Matsuura, A. Hara, M. Kato, Y. Deyashiki, Y. Miyabe, S. Ishikura, T. Sugiyama, and Y. Katagiri (1998)
J. Pharmacol. Exp. Ther. 285, 1096-1103
 |  Abstract »  |  Full Text »

Differential Effects of Chronic Antidepressant Treatment on Swim Stress- and Fluoxetine-Induced Secretion of Corticosterone and Progesterone.

G. E. Duncan, D. J. Knapp, S. W. Carson, and G. R. Breese (1998)
J. Pharmacol. Exp. Ther. 285, 579-587
 |  Abstract »  |  Full Text »

Dehydroepiandrosterone: A potential signalling molecule for neocortical organization during development.

N. A. Compagnone and S. H. Mellon (1998)
PNAS 95, 4678-4683
 |  Abstract »  |  Full Text »  |  PDF »

Transient Expression of the 5{alpha}-Reductase Type 2 Isozyme in the Rat Brain in Late Fetal and Early Postnatal Life.

A. Poletti, P. Negri-Cesi, M. Rabuffetti, A. Colciago, F. Celotti, and L. Martini (1998)
Endocrinology 139, 2171-2178
 |  Abstract »  |  Full Text »  |  PDF »

Reversal of Behavioral Effects of Pentylenetetrazol by the Neuroactive Steroid Ganaxolone.

M. Beekman, J. T. Ungard, M. Gasior, R. B. Carter, D. Dijkstra, S. R. Goldberg, and J. M. Witkin (1998)
J. Pharmacol. Exp. Ther. 284, 868-877
 |  Abstract »  |  Full Text »

Premenstrual Syndrome -- Pathophysiologic Considerations.

J. F. Mortola (1998)
N. Engl. J. Med. 338, 256-257
 |  Full Text »

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