Science 14 February 1986: Vol. 231. no. 4739, pp. 699 - 704 DOI: 10.1126/science.3080805

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Articles

Eukaryotic Protein Domains as Functional Units of Cellular Evolution.

J. Jin, X. Xie, C. Chen, J. G. Park, C. Stark, D. A. James, M. Olhovsky, R. Linding, Y. Mao, and T. Pawson (2009)
Science Signaling 2, ra76
 |  Abstract »  |  Full Text »  |  PDF »

Global analysis of mutual interaction surfaces of nucleosomes with comprehensive point mutants.

M. Sakamoto, S. Noguchi, S. Kawashima, Y. Okada, T. Enomoto, M. Seki, and M. Horikoshi (2009)
Genes Cells 14, 1271-1330
 |  Abstract »  |  Full Text »  |  PDF »

NADP Regulates the Yeast GAL Induction System.

P. R. Kumar, Y. Yu, R. Sternglanz, S. A. Johnston, and L. Joshua-Tor (2008)
Science 319, 1090-1092
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Activation Domains of the Candida albicans Gcn4p and Gal4p Homologs.

M. Martchenko, A. Levitin, and M. Whiteway (2007)
Eukaryot. Cell 6, 291-301
 |  Abstract »  |  Full Text »  |  PDF »

Dual Activators of the Sterol Biosynthetic Pathway of Saccharomyces cerevisiae: Similar Activation/Regulatory Domains but Different Response Mechanisms.

B. S. J. Davies, H. S. Wang, and J. Rine (2005)
Mol. Cell. Biol. 25, 7375-7385
 |  Abstract »  |  Full Text »  |  PDF »

Experimental and bioinformatic approaches for interrogating protein-protein interactions to determine protein function.

A. Droit, G. G Poirier, and J. M Hunter (2005)
J. Mol. Endocrinol. 34, 263-280
 |  Abstract »  |  Full Text »  |  PDF »

Functional analysis of the transcriptional activator XlnR from Aspergillus niger.

A. A. Hasper, L. M. Trindade, D. van der Veen, A. J. J. van Ooyen, and L. H. de Graaff (2004)
Microbiology 150, 1367-1375
 |  Abstract »  |  Full Text »  |  PDF »

Formation of Boundaries of Transcriptionally Silent Chromatin by Nucleosome-Excluding Structures.

X. Bi, Q. Yu, J. J. Sandmeier, and Y. Zou (2004)
Mol. Cell. Biol. 24, 2118-2131
 |  Abstract »  |  Full Text »  |  PDF »

Dendrite Development Regulated by CREST, a Calcium-Regulated Transcriptional Activator.

H. Aizawa, S.-C. Hu, K. Bobb, K. Balakrishnan, G. Ince, I. Gurevich, M. Cowan, and A. Ghosh (2004)
Science 303, 197-202
 |  Abstract »  |  Full Text »  |  PDF »

Hypoxia Inducible Double Plasmid System for Myocardial Ischemia Gene Therapy.

Y. Tang, M. Jackson, K. Qian, and M. I. Phillips (2002)
Hypertension 39, 695-698
 |  Abstract »  |  Full Text »  |  PDF »

Role for Homodimerization in Growth Deregulation by E2a Fusion Proteins.

R. Bayly and D. P. LeBrun (2000)
Mol. Cell. Biol. 20, 5789-5796
 |  Abstract »  |  Full Text »  |  PDF »

The Only Function of Grauzone Required for Drosophila Oocyte Meiosis Is Transcriptional Activation of the cortex Gene.

E. Harms, T. Chu, G. Henrion, and S. Strickland (2000)
Genetics 155, 1831-1839
 |  Abstract »  |  Full Text »

Activation of gene expression by small molecule transcription factors.

A. K. Mapp, A. Z. Ansari, M. Ptashne, and P. B. Dervan (2000)
PNAS 97, 3930-3935
 |  Abstract »  |  Full Text »  |  PDF »

Ser298 of MITF, a mutation site in Waardenburg syndrome type 2, is a phosphorylation site with functional significance.

K. Takeda, C. Takemoto, I. Kobayashi, A. Watanabe, Y. Nobukuni, D. E. Fisher, and M. Tachibana (2000)
Hum. Mol. Genet. 9, 125-132
 |  Abstract »  |  Full Text »  |  PDF »

The Gal3p-Gal80p-Gal4p Transcription Switch of Yeast: Gal3p Destabilizes the Gal80p-Gal4p Complex in Response to Galactose and ATP.

A. K. Sil, S. Alam, P. Xin, L. Ma, M. Morgan, C. M. Lebo, M. P. Woods, and J. E. Hopper (1999)
Mol. Cell. Biol. 19, 7828-7840
 |  Abstract »  |  Full Text »  |  PDF »

Gene silencing via protein-mediated subcellular localization of DNA.

S.-K. Kim and J. C. Wang (1999)
PNAS 96, 8557-8561
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Induction by Aromatic Amino Acids in Saccharomyces cerevisiae.

I. Iraqui, S. Vissers, B. Andre, and A. Urrestarazu (1999)
Mol. Cell. Biol. 19, 3360-3371
 |  Abstract »  |  Full Text »  |  PDF »

Allele-Specific Interactions Between ttg and gl1 During Trichome Development in Arabidopsis thaliana.

J. C. Larkin, J. D. Walker, A. C. Bolognesi-Winfield, J. C. Gray, and A. R. Walker (1999)
Genetics 151, 1591-1604
 |  Abstract »  |  Full Text »

Cell-Type-Dependent Activity of the Ubiquitous Transcription Factor USF in Cellular Proliferation and Transcriptional Activation.

Y. Qyang, X. Luo, T. Lu, P. M. Ismail, D. Krylov, C. Vinson, and M. Sawadogo (1999)
Mol. Cell. Biol. 19, 1508-1517
 |  Abstract »  |  Full Text »  |  PDF »

Salmonella enteritidis: AmpC Plasmid-Mediated Inducible beta -Lactamase (DHA-1) with an ampR Gene from Morganella morganii.

G. Barnaud, G. Arlet, C. Verdet, O. Gaillot, P. H. Lagrange, and A. Philippon (1998)
Antimicrob. Agents Chemother. 42, 2352-2358
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Cytoplasmic Protein That Specifically Binds to Nuclear Localization Signal Motifs.

S. Li, C.-Y. Ku, A. A. Farmer, Y.-S. Cong, C.-F. Chen, and W.-H. Lee (1998)
J. Biol. Chem. 273, 6183-6189
 |  Abstract »  |  Full Text »  |  PDF »

Plant science in lac: A continuation of using tools from Escherichia coli in studying gene function in heterologous systems.

J. Messing (1998)
PNAS 95, 93-94
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Nuclear entry, oligomerization, and DNA binding of the Drosophila heat shock transcription factor are regulated by a unique nuclear localization sequence..

E Zandi, T N Tran, W Chamberlain, and C S Parker (1997)
Genes & Dev. 11, 1299-1314
 |  Abstract »  |  PDF »

The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-alpha Subunit of the Nuclear Transport Signal Receptor.

C.-F. Chen, S. Li, Y. Chen, P.-L. Chen, Z. D. Sharp, and W.-H. Lee (1996)
J. Biol. Chem. 271, 32863-32868
 |  Abstract »  |  Full Text »  |  PDF »

Transactivation by Rtg1p, a Basic Helix-Loop-Helix Protein That Functions in Communication between Mitochondria and the Nucleus in Yeast.

B. A. Rothermel, A. W. Shyjan, J. L. Etheredge, and R. A. Butow (1995)
J. Biol. Chem. 270, 29476-29482
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Positive Elements Sensitive to Glucose in the Promoter of the FBP1 Gene from Yeast.

O. Vincent and J. M. Gancedo (1995)
J. Biol. Chem. 270, 12832-12838
 |  Abstract »  |  Full Text »  |  PDF »

Promoter-proximal pausing of RNA polymerase II defines a general rate-limiting step after transcription initiation..

A Krumm, L B Hickey, and M Groudine (1995)
Genes & Dev. 9, 559-572
 |  Abstract »  |  PDF »

Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions..

J A Lefstin, J R Thomas, and K R Yamamoto (1994)
Genes & Dev. 8, 2842-2856
 |  Abstract »  |  PDF »

Nucleosome disruption by transcription factor binding in yeast.

R. Morse (1993)
Science 262, 1563-1566
 |  Abstract »  |  PDF »

NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.

J. Omichinski, G. Clore, O Schaad, G Felsenfeld, C Trainor, E Appella, S. Stahl, and A. Gronenborn (1993)
Science 261, 438-446
 |  Abstract »  |  PDF »

Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit..

G Fang, J T Gray, and T R Cech (1993)
Genes & Dev. 7, 870-882
 |  Abstract »  |  PDF »

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit..

T Durfee, K Becherer, P L Chen, S H Yeh, Y Yang, A E Kilburn, W H Lee, and S J Elledge (1993)
Genes & Dev. 7, 555-569
 |  Abstract »  |  PDF »

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

A. Brand and N Perrimon (1993)
Development 118, 401-415
 |  Abstract »  |  PDF »

The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence..

L S Tiley, S J Madore, M H Malim, and B R Cullen (1992)
Genes & Dev. 6, 2077-2087
 |  Abstract »  |  PDF »

Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein.

D. Mendel, P. Khavari, P. Conley, M. Graves, L. Hansen, A Admon, and G. Crabtree (1991)
Science 254, 1762-1767
 |  Abstract »  |  PDF »

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex..

N Tanese, B F Pugh, and R Tjian (1991)
Genes & Dev. 5, 2212-2224
 |  Abstract »  |  PDF »

Pheromone-dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation..

D Song, J W Dolan, Y L Yuan, and S Fields (1991)
Genes & Dev. 5, 741-750
 |  Abstract »  |  PDF »

Functional domains of the yeast transcription/replication factor MCM1..

C Christ and B K Tye (1991)
Genes & Dev. 5, 751-763
 |  Abstract »  |  PDF »

Template supercoiling by a chimera of yeast GAL4 protein and phage T7 RNA polymerase.

E. Ostrander, P Benedetti, and J. Wang (1990)
Science 249, 1261-1265
 |  Abstract »  |  PDF »

Differentiation of mouse erythroleukemia cells enhanced by alternatively spliced c-myb mRNA.

B. Weber, E. Westin, and M. Clarke (1990)
Science 249, 1291-1293
 |  Abstract »  |  PDF »

Presence of a potent transcription activating sequence in the p53 protein.

S Fields and S. Jang (1990)
Science 249, 1046-1049
 |  Abstract »  |  PDF »

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene.

L Raycroft, H. Wu, and G Lozano (1990)
Science 249, 1049-1051
 |  Abstract »  |  PDF »

Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene..

A D Friedman and S L McKnight (1990)
Genes & Dev. 4, 1416-1426
 |  Abstract »  |  PDF »

A potent GAL4 derivative activates transcription at a distance in vitro.

M Carey, J Leatherwood, and M Ptashne (1990)
Science 247, 710-712
 |  Abstract »  |  PDF »

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif..

H Beckmann, L K Su, and T Kadesch (1990)
Genes & Dev. 4, 167-179
 |  Abstract »  |  PDF »

The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily..

W A Segraves and D S Hogness (1990)
Genes & Dev. 4, 204-219
 |  Abstract »  |  PDF »

Regulated phosphorylation and dephosphorylation of GAL4, a transcriptional activator..

L M Mylin, J P Bhat, and J E Hopper (1989)
Genes & Dev. 3, 1157-1165
 |  Abstract »  |  PDF »

Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer..

S L Forsburg and L Guarente (1989)
Genes & Dev. 3, 1166-1178
 |  Abstract »  |  PDF »

A protein involved in minichromosome maintenance in yeast binds a transcriptional enhancer conserved in eukaryotes..

S Passmore, R Elble, and B K Tye (1989)
Genes & Dev. 3, 921-935
 |  Abstract »  |  PDF »

The yeast transcription activator PRTF, a homolog of the mammalian serum response factor, is encoded by the MCM1 gene..

E E Jarvis, K L Clark, and G F Sprague (1989)
Genes & Dev. 3, 936-945
 |  Abstract »  |  PDF »

Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements..

T Williams, A Admon, B Luscher, and R Tjian (1988)
Genes & Dev. 2, 1557-1569
 |  Abstract »  |  PDF »

Activation of the U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elements..

M Tanaka, U Grossniklaus, W Herr, and N Hernandez (1988)
Genes & Dev. 2, 1764-1778
 |  Abstract »  |  PDF »

Selective activation of transcription by a novel CCAAT binding factor.

S. Maity, P. Golumbek, G Karsenty, and B de Crombrugghe (1988)
Science 241, 582-585
 |  Abstract »  |  PDF »

Mutations that alter both localization and production of a yeast nuclear protein..

P A Silver, A Chiang, and I Sadler (1988)
Genes & Dev. 2, 707-717
 |  Abstract »  |  PDF »

The steroid and thyroid hormone receptor superfamily.

R. Evans (1988)
Science 240, 889-895
 |  Abstract »  |  PDF »

Cooperative and Positional Independent trans-Activation Domains of the Human Glucocorticoid Receptor.

R.M. Evans and S.M. Hollenberg (1988)
Cold Spring Harb Symp Quant Biol 53, 813-818
 |  Abstract »  |  PDF »

Expression and Function of the Human Estrogen Receptor in Yeast.

J.H. White, D. Metzger, and P. Chambon (1988)
Cold Spring Harb Symp Quant Biol 53, 819-828
 |  Abstract »  |  PDF »

GAL1-GAL10 divergent promoter region of Saccharomyces cerevisiae contains negative control elements in addition to functionally separate and possibly overlapping upstream activating sequences..

R W West, S M Chen, H Putz, G Butler, and M Banerjee (1987)
Genes & Dev. 1, 1118-1131
 |  Abstract »  |  PDF »

Transcriptional regulation in the yeast life cycle.

K Nasmyth and D Shore (1987)
Science 237, 1162-1170
 |  Abstract »  |  PDF »

Homeo domain of the yeast repressor alpha 2 is a sequence-specific DNA-binding domain but is not sufficient for repression.

M. Hall and A. Johnson (1987)
Science 237, 1007-1012
 |  Abstract »  |  PDF »

Zinc Fingers: A Novel Protein Fold for Nucleic Acid Recognition.

A. Klug and D. Rhodes (1987)
Cold Spring Harb Symp Quant Biol 52, 473-482
 |  Abstract »  |  PDF »

Human Steroid Receptors and erbA Proto-oncogene Products: Members of a New Superfamily of Enhancer Binding Proteins.

C. Weinberger, V. Giguere, S. Hollenberg, M.G. Rosenfeld, and R.M. Evans (1986)
Cold Spring Harb Symp Quant Biol 51, 759-772
 |  Abstract »  |  PDF »

RINT-1, a Novel Rad50-interacting Protein, Participates in Radiation-induced G2/M Checkpoint Control.

J. Xiao, C.-C. Liu, P.-L. Chen, and W.-H. Lee (2001)
J. Biol. Chem. 276, 6105-6111
 |  Abstract »  |  Full Text »  |  PDF »

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