Science 22 November 1985: Vol. 230. no. 4728, pp. 912 - 916 DOI: 10.1126/science.3904002

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Articles

Maturation of Adult {beta}-Cells Revealed Using a Pdx1/Insulin Dual-Reporter Lentivirus.

M. Szabat, D. S. Luciani, J. M. Piret, and J. D. Johnson (2009)
Endocrinology 150, 1627-1635
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Regulation of the Salivary Histatin Gene: Finding of a Strong Positive Regulatory Element and Its Binding Protein.

Y. Imamura, Y. Fujigaki, Y. Oomori, K. Ouryouji, S. Yanagisawa, H. Miyazawa, and P.-L. Wang (2009)
J. Biochem. 145, 279-288
 |  Abstract »  |  Full Text »  |  PDF »

The Basic Helix-Loop-Helix Transcription Factor NeuroD1 Facilitates Interaction of Sp1 with the Secretin Gene Enhancer.

S. K. Ray and A. B. Leiter (2007)
Mol. Cell. Biol. 27, 7839-7847
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of the Gene Encoding GPR40, a Fatty Acid Receptor Expressed Selectively in Pancreatic beta Cells.

R. Bartoov-Shifman, G. Ridner, K. Bahar, N. Rubins, and M. D. Walker (2007)
J. Biol. Chem. 282, 23561-23571
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Thyroid-Stimulating Hormone {beta}-Subunit Gene by LIM Homeodomain Transcription Factor Lhx2.

K. K. Kim, S. B. Song, K. I. Kang, M. Rhee, and K. E. Kim (2007)
Endocrinology 148, 3468-3476
 |  Abstract »  |  Full Text »  |  PDF »

Comparative Analysis of Insulin Gene Promoters: Implications for Diabetes Research.

C. W. Hay and K. Docherty (2006)
Diabetes 55, 3201-3213
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of PDX-1 in activation of human insulin gene transcription.

J. Le Lay and R. Stein (2006)
J. Endocrinol. 188, 287-294
 |  Abstract »  |  Full Text »  |  PDF »

Interactions between Areas I and II Direct pdx-1 Expression Specifically to Islet Cell Types of the Mature and Developing Pancreas.

J. C. Van Velkinburgh, S. E. Samaras, K. Gerrish, I. Artner, and R. Stein (2005)
J. Biol. Chem. 280, 38438-38444
 |  Abstract »  |  Full Text »  |  PDF »

Pituitary homeobox 1 (Pitx1) stimulates rat LH{beta} gene expression via two functional DNA-regulatory regions.

Q. Jiang, K.-H. Jeong, C. D Horton, and L. M Halvorson (2005)
J. Mol. Endocrinol. 35, 145-158
 |  Abstract »  |  Full Text »  |  PDF »

Synergy between Activin A and Gonadotropin-Releasing Hormone in Transcriptional Activation of the Rat Follicle-Stimulating Hormone-{beta} Gene.

S. J. Gregory, C. T. Lacza, A. A. Detz, S. Xu, L. A. Petrillo, and U. B. Kaiser (2005)
Mol. Endocrinol. 19, 237-254
 |  Abstract »  |  Full Text »  |  PDF »

Global Inhibition of Lef1/Tcf-dependent Wnt Signaling at Its Nuclear End Point Abrogates Development in Transgenic Xenopus Embryos.

T. Deroo, T. Denayer, F. Van Roy, and K. Vleminckx (2004)
J. Biol. Chem. 279, 50670-50675
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Inducible Cyclic AMP Early Repressor Inhibits Transactivation of Genes and Cell Proliferation in Pancreatic {beta} Cells.

A. Inada, Y. Hamamoto, Y. Tsuura, J.-i. Miyazaki, S. Toyokuni, Y. Ihara, K. Nagai, Y. Yamada, S. Bonner-Weir, and Y. Seino (2004)
Mol. Cell. Biol. 24, 2831-2841
 |  Abstract »  |  Full Text »  |  PDF »

Role of intrinsic DNA binding specificity in defining target genes of the mammalian transcription factor PDX1.

A. Liberzon, G. Ridner, and M. D. Walker (2004)
Nucleic Acids Res. 32, 54-64
 |  Abstract »  |  Full Text »  |  PDF »

Ras Signaling and Transcriptional Synergy at a Flexible Ets-1/Pit-1 Composite DNA Element Is Defined by the Assembly of Selective Activation Domains.

D. L. Duval, A. Jean, and A. Gutierrez-Hartmann (2003)
J. Biol. Chem. 278, 39684-39696
 |  Abstract »  |  Full Text »  |  PDF »

Novel Transcriptional Potentiation of BETA2/NeuroD on the Secretin Gene Promoter by the DNA-Binding Protein Finb/RREB-1.

S. K. Ray, J. Nishitani, M. W. Petry, M. Y. Fessing, and A. B. Leiter (2003)
Mol. Cell. Biol. 23, 259-271
 |  Abstract »  |  Full Text »

Differential, Tissue-specific, Transcriptional Regulation of Apolipoprotein B Secretion by Transforming Growth Factor beta.

K. Singh, O. A. Batuman, H. O. Akman, M. H. Kedees, V. Vakil, and M. M. Hussain (2002)
J. Biol. Chem. 277, 39515-39524
 |  Abstract »  |  Full Text »  |  PDF »

Protein Engineering of Protein Kinase A Catalytic Subunits Results in the Acquisition of Novel Inhibitor Sensitivity.

C. M. Niswender, R. W. Ishihara, L. M. Judge, C. Zhang, K. M. Shokat, and G. S. McKnight (2002)
J. Biol. Chem. 277, 28916-28922
 |  Abstract »  |  Full Text »  |  PDF »

Pituitary Homeobox 1 Activates the Rat FSH{beta} (rFSH{beta}) Gene through Both Direct and Indirect Interactions with the rFSH{beta} Gene Promoter.

M. M. Zakaria, K.-H. Jeong, C. Lacza, and U. B. Kaiser (2002)
Mol. Endocrinol. 16, 1840-1852
 |  Abstract »  |  Full Text »  |  PDF »

Novel Binding of HuR and Poly(C)-binding Protein to a Conserved UC-rich Motif within the 3'-Untranslated Region of the Androgen Receptor Messenger RNA.

B. B. Yeap, D. C. Voon, J. P. Vivian, R. K. McCulloch, A. M. Thomson, K. M. Giles, M. F. Czyzyk-Krzeska, H. Furneaux, M. C. J. Wilce, J. A. Wilce, et al. (2002)
J. Biol. Chem. 277, 27183-27192
 |  Abstract »  |  Full Text »  |  PDF »

The Human Prepro-orexin Gene Regulatory Region That Activates Gene Expression in the Lateral Region and Represses It in the Medial Regions of the Hypothalamus.

T. Moriguchi, T. Sakurai, S. Takahashi, K. Goto, and M. Yamamoto (2002)
J. Biol. Chem. 277, 16985-16992
 |  Abstract »  |  Full Text »  |  PDF »

Two Initiator-like Elements Are Required for the Combined Activation of the Human Apolipoprotein C-III Promoter by Upstream Stimulatory Factor and Hepatic Nuclear Factor-4.

D. Pastier, J.-M. Lacorte, J. Chambaz, P. Cardot, and A. Ribeiro (2002)
J. Biol. Chem. 277, 15199-15206
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Transforming Growth Factor beta Signaling and Smad-dependent Activation of Transcription by the Latent Membrane Protein 1 of Epstein-Barr Virus.

V. Prokova, G. Mosialos, and D. Kardassis (2002)
J. Biol. Chem. 277, 9342-9350
 |  Abstract »  |  Full Text »  |  PDF »

A Genetic Defect in {beta}-Cell Gene Expression Segregates Independently From the fa Locus in the ZDF Rat.

S. C. Griffen, J. Wang, and M. S. German (2001)
Diabetes 50, 63-68
 |  Abstract »  |  Full Text »

Sp1, Steroidogenic Factor 1 (SF-1), and Early Growth Response Protein 1 (Egr-1) Binding Sites Form a Tripartite Gonadotropin-Releasing Hormone Response Element in the Rat Luteinizing Hormone-{beta} Gene Promoter: an Integral Role for SF-1.

U. B. Kaiser, L. M. Halvorson, and M. T. Chen (2000)
Mol. Endocrinol. 14, 1235-1245
 |  Abstract »  |  Full Text »

J Domain-Independent Regulation of the Rb Family by Polyomavirus Large T Antigen.

Q. Sheng, T. M. Love, and B. Schaffhausen (2000)
J. Virol. 74, 5280-5290
 |  Abstract »  |  Full Text »

The RIPE3b1 Activator of the Insulin Gene Is Composed of a Protein(s) of Approximately 43 kDa, Whose DNA Binding Activity Is Inhibited by Protein Phosphatase Treatment.

L. Zhao, M. A. Cissell, E. Henderson, R. Colbran, and R. Stein (2000)
J. Biol. Chem. 275, 10532-10537
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Human Histo-blood Group ABO Genes Is Dependent upon DNA Methylation of the Promoter Region.

Y. Kominato, Y. Hata, H. Takizawa, T. Tsuchiya, J. Tsukada, and F.-i. Yamamoto (1999)
J. Biol. Chem. 274, 37240-37250
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a Novel Cis-element That Regulates Fas Ligand Expression in Corneal Endothelial Cells.

J. Zhang, B. Ma, A. Marshak-Rothstein, and A. Fine (1999)
J. Biol. Chem. 274, 26537-26542
 |  Abstract »  |  Full Text »  |  PDF »

The Activation of the Rat Copper/Zinc Superoxide Dismutase Gene by Hydrogen Peroxide through the Hydrogen Peroxide-responsive Element and by Paraquat and Heat Shock through the Same Heat Shock Element.

H. Y. Yoo, M. S. Chang, and H. M. Rho (1999)
J. Biol. Chem. 274, 23887-23892
 |  Abstract »  |  Full Text »  |  PDF »

E.B. Wilson Lecture, 1998. Eukaryotic RNAs: Once More from the Beginning ....

J. E. Darnell Jr. (1999)
Mol. Biol. Cell 10, 1685-1692
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Modulation of Tumor Necrosis Factor and Interleukin-1-dependent NF-kappa B Activity by mPLK/IRAK.

E. Vig, M. Green, Y. Liu, D. B. Donner, N. Mukaida, M. G. Goebl, and M. A. Harrington (1999)
J. Biol. Chem. 274, 13077-13084
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Induction and Translocation of Egr-1 in Response to Mechanical Strain in Vascular Smooth Muscle Cells.

H. Morawietz, Y.-H. Ma, F. Vives, E. Wilson, V. P. Sukhatme, J. Holtz, and H. E. Ives (1999)
Circ. Res. 84, 678-687
 |  Abstract »  |  Full Text »  |  PDF »

ROR{alpha} Augments Thyroid Hormone Receptor-Mediated Transcriptional Activation.

N. Koibuchi, Y. Liu, H. Fukuda, A. Takeshita, P. M. Yen, and W. W. Chin (1999)
Endocrinology 140, 1356-1364
 |  Abstract »  |  Full Text »

Cooperative Binding of Upstream Stimulatory Factor and Hepatic Nuclear Factor 4 Drives the Transcription of the Human Apolipoprotein A-II Gene.

A. Ribeiro, D. Pastier, D. Kardassis, J. Chambaz, and P. Cardot (1999)
J. Biol. Chem. 274, 1216-1225
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1.

M. Aoki, A. Hecht, U. Kruse, R. Kemler, and P. K. Vogt (1999)
PNAS 96, 139-144
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family.

M Maconochie, R Krishnamurthy, S Nonchev, P Meier, M Manzanares, P. Mitchell, and R Krumlauf (1999)
Development 126, 1483-1494
 |  Abstract »  |  PDF »

The Protein Kinase C System Acts through the Early Growth Response Protein 1 to Increase LH{beta} Gene Expression in Synergy with Steroidogenic Factor-1.

L. M. Halvorson, U. B. Kaiser, and W. W. Chin (1999)
Mol. Endocrinol. 13, 106-116
 |  Abstract »  |  Full Text »

Lack of Coactivator Interaction Can Be a Mechanism for Dominant Negative Activity by Mutant Thyroid Hormone Receptors.

Y. Liu, A. Takeshita, S. Misiti, W. W. Chin, and P. M. Yen (1998)
Endocrinology 139, 4197-4204
 |  Abstract »  |  Full Text »  |  PDF »

A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets.

M. Sander, S. C. Griffen, J. Huang, and M. S. German (1998)
PNAS 95, 11572-11577
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of the Glucagon and Insulin I Gene Promoters by the Basic Helix-Loop-Helix Transcription Factors E47 and BETA2.

E. Dumonteil, B. Laser, I. Constant, and J. Philippe (1998)
J. Biol. Chem. 273, 19945-19954
 |  Abstract »  |  Full Text »  |  PDF »

Steroidogenic Factor-1 and Early Growth Response Protein 1 Act through Two Composite DNA Binding Sites to Regulate Luteinizing Hormone beta -Subunit Gene Expression.

L. M. Halvorson, M. Ito, J. L. Jameson, and W. W. Chin (1998)
J. Biol. Chem. 273, 14712-14720
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Mechanisms Regulate Imprinting of the Mouse Distal Chromosome 7 Gene Cluster.

T. Caspary, M. A. Cleary, C. C. Baker, X.-J. Guan, and S. M. Tilghman (1998)
Mol. Cell. Biol. 18, 3466-3474
 |  Abstract »  |  Full Text »

Sp1 Binds to the Rat Luteinizing Hormone beta  (LHbeta ) Gene Promoter and Mediates Gonadotropin-releasing Hormone-stimulated Expression of the LHbeta Subunit Gene.

U. B. Kaiser, E. Sabbagh, M. T. Chen, W. W. Chin, and B. D. Saunders (1998)
J. Biol. Chem. 273, 12943-12951
 |  Abstract »  |  Full Text »  |  PDF »

p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene.

Y. Qiu, A. Sharma, and R. Stein (1998)
Mol. Cell. Biol. 18, 2957-2964
 |  Abstract »  |  Full Text »

Identification of cis-Acting Deoxyribonucleic Acid Elements That Mediate Gonadotropin-Releasing Hormone Stimulation of the Rat Luteinizing Hormone {beta}-Subunit Gene.

U. B. Kaiser, E. Sabbagh, B. D. Saunders, and W. W. Chin (1998)
Endocrinology 139, 2443-2451
 |  Abstract »  |  Full Text »  |  PDF »

Type I Protein C Deficiency Caused by Disruption of a Hepatocyte Nuclear Factor (HNF)-6/HNF-1 Binding Site in the Human Protein C Gene Promoter.

C. A. Spek, V. J. Lannoy, F. P. Lemaigre, G. G. Rousseau, R. M. Bertina, and P. H. Reitsma (1998)
J. Biol. Chem. 273, 10168-10173
 |  Abstract »  |  Full Text »  |  PDF »

GATA Factor-dependent Regulation of Cardiac m2 Muscarinic Acetylcholine Gene Transcription.

M. L. Rosoff and N. M. Nathanson (1998)
J. Biol. Chem. 273, 9124-9129
 |  Abstract »  |  Full Text »  |  PDF »

Lens-Specific Gene Recruitment of zeta -Crystallin through Pax6, Nrl-Maf, and Brain Suppressor Sites.

R. Sharon-Friling, J. Richardson, S. Sperbeck, D. Lee, M. Rauchman, R. Maas, A. Swaroop, and G. Wistow (1998)
Mol. Cell. Biol. 18, 2067-2076
 |  Abstract »  |  Full Text »

A Short Proximal Promoter and the Distal Hepatic Control Region-1 (HCR-1) Contribute to the Liver Specificity of the Human Apolipoprotein C-II Gene. HEPATIC ENHANCEMENT BY HCR-1 REQUIRES TWO PROXIMAL HORMONE RESPONSE ELEMENTS WHICH HAVE DIFFERENT BINDING SPECIFICITIES FOR ORPHAN RECEPTORS HNF-4, ARP-1, and EAR-2.

P. Vorgia, V. I. Zannis, and D. Kardassis (1998)
J. Biol. Chem. 273, 4188-4196
 |  Abstract »  |  Full Text »  |  PDF »

Serine 257 Phosphorylation Regulates Association of Polyomavirus Middle T Antigen with 14-3-3 Proteins.

X. Cullere, P. Rose, U. Thathamangalam, A. Chatterjee, K. P. Mullane, D. C. Pallas, T. L. Benjamin, T. M. Roberts, and B. S. Schaffhausen (1998)
J. Virol. 72, 558-563
 |  Abstract »  |  Full Text »  |  PDF »

An Inhibitory Region of the DNA-Binding Domain of Thyroid Hormone Receptor Blocks Hormone-Dependent Transactivation.

Y. Liu, A. Takeshita, T. Nagaya, A. Baniahmad, W. W. Chin, and P. M. Yen (1998)
Mol. Endocrinol. 12, 34-44
 |  Abstract »  |  Full Text »

cis-Acting Sequences That Mediate Induction of ß-Myosin Heavy Chain Gene Expression During Left Ventricular Hypertrophy due to Aortic Constriction.

K. Hasegawa, S. J. Lee, S. M. Jobe, B. E. Markham, and R. N. Kitsis (1997)
Circulation 96, 3943-3953
 |  Abstract »  |  Full Text »

Transcription of Human ABO Histo-blood Group Genes Is Dependent upon Binding of Transcription Factor CBF/NF-Y to Minisatellite Sequence.

Y. Kominato, T. Tsuchiya, N. Hata, H. Takizawa, and F.-i. Yamamoto (1997)
J. Biol. Chem. 272, 25890-25898
 |  Abstract »  |  Full Text »  |  PDF »

Activation of CAAT Enhancer-binding Protein delta  (C/EBPdelta ) by Interleukin-1 Negatively Influences Apolipoprotein C-III Expression.

J.-M. Lacorte, E. Ktistaki, A. Beigneux, V. I. Zannis, J. Chambaz, and I. Talianidis (1997)
J. Biol. Chem. 272, 23578-23584
 |  Abstract »  |  Full Text »  |  PDF »

Glucose-Stimulated Genes and Prospects of Gene Therapy for Type I Diabetes.

D. Mitanchez, B. Doiron, R. Chen, and A. Kahn (1997)
Endocr. Rev. 18, 520-540
 |  Abstract »  |  Full Text »  |  PDF »

Retinoid X Receptors in the Kidney: Their Protein Expression and Functional Significance.

A. Sugawara, N. Sanno, N. Takahashi, R. Y. Osamura, and K. Abe (1997)
Endocrinology 138, 3175-3180
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic Regulation of m2 Muscarinic Acetylcholine Receptor Desensitization and Sequestration by G Protein-coupled Receptor Kinase-2 and beta -Arrestin-1.

M. L. Schlador and N. M. Nathanson (1997)
J. Biol. Chem. 272, 18882-18890
 |  Abstract »  |  Full Text »  |  PDF »

Two Proximal Activating Protein-1-Binding Sites Are Sufficient to Stimulate Transcription of the Ovine Follicle-Stimulating Hormone-{beta} Gene.

B. D. Strahl, H.-J. Huang, N. R. Pedersen, J. C. Wu, B. R. Ghosh, and W. L. Miller (1997)
Endocrinology 138, 2621-2631
 |  Abstract »  |  Full Text »  |  PDF »

beta -Trace Gene Expression Is Regulated by a Core Promoter and a Distal Thyroid Hormone Response Element.

D. M. White, T. Takeda, L. J. DeGroot, K. Stefansson, and B. G. W. Arnason (1997)
J. Biol. Chem. 272, 14387-14393
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-specific and Developmental Regulation of the Rat Insulin II Gene Enhancer, RIPE3, in Transgenic Mice.

C. M.M. Stellrecht, F. J. DeMayo, M. J. Finegold, and M.-J. Tsai (1997)
J. Biol. Chem. 272, 3567-3572
 |  Abstract »  |  Full Text »  |  PDF »

Mutant and Wild-Type Androgen Receptors Exhibit Cross-Talk on Androgen-, Glucocorticoid-, and Progesterone-Mediated Transcription.

P. M. Yen, Y. Liu, J. J. Palvimo, M. Trifiro, J. Whang, L. Pinsky, O. A. Jänne, and W. W. Chin (1997)
Mol. Endocrinol. 11, 162-171
 |  Abstract »  |  Full Text »

Distal Apolipoprotein C-III Regulatory Elements F to J Act as a General Modular Enhancer for Proximal Promoters That Contain Hormone Response Elements: Synergism Between Hepatic Nuclear Factor-4 Molecules Bound to the Proximal Promoter and Distal Enhancer Sites.

D. Kardassis, I. Tzameli, M. Hadzopoulou-Cladaras, I. Talianidis, and V. Zannis (1997)
Arterioscler Thromb Vasc Biol 17, 222-232
 |  Abstract »  |  Full Text »

Isolation and characterization of the chicken m2 acetylcholine receptor promoter region: Induction of gene transcription by leukemia inhibitory factor and ciliary neurotrophic factor.

M. L. Rosoff, J. Wei, and N. M. Nathanson (1996)
PNAS 93, 14889-14894
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Activation of the Cu,Zn-Superoxide Dismutase Gene through the AP2 Site by Ginsenoside Rb2 Extracted from a Medicinal Plant, Panax ginseng.

Y. H. Kim, K. H. Park, and H. M. Rho (1996)
J. Biol. Chem. 271, 24539-24543
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Signaling Pathways Control the Activation of the CEF-4/9E3 Cytokine Gene by pp60v-src.

B. Bojovic, N. Rodrigues, M. Dehbi, and P.-A. Bedard (1996)
J. Biol. Chem. 271, 22528-22537
 |  Abstract »  |  Full Text »  |  PDF »

Replication Protein A Is a Component of a Complex That Binds the Human Metallothionein IIA Gene Transcription Start Site.

C.-M. Tang, A. E. Tomkinson, W. S. Lane, M. S. Wold, and E. Seto (1996)
J. Biol. Chem. 271, 21637-21644
 |  Abstract »  |  Full Text »  |  PDF »

Isolation and Characterization of an Avian Slow Myosin Heavy Chain Gene Expressed during Embryonic Skeletal Muscle Fiber Formation.

W. Nikovits Jr., G. F. Wang, J. L. Feldman, J. B. Miller, R. Wade, L. Nelson, and F. E. Stockdale (1996)
J. Biol. Chem. 271, 17047-17056
 |  Abstract »  |  Full Text »  |  PDF »

Vitamin D Receptors Repress Basal Transcription and Exert Dominant Negative Activity on Triiodothyronine-mediated Transcriptional Activity.

P. M. Yen, Y. Liu, A. Sugawara, and W. W. Chin (1996)
J. Biol. Chem. 271, 10910-10916
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of Luteinizing Hormone beta Gene Promoter Activity by the Orphan Nuclear Receptor, Steroidogenic Factor-1.

L. M. Halvorson, U. B. Kaiser, and W. W. Chin (1996)
J. Biol. Chem. 271, 6645-6650
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Region Required for Subtype-specific Agonist-induced Sequestration of the m2 Muscarinic Acetylcholine Receptor.

P. S. Goldman, M. L. Schlador, R. A. Shapiro, and N. M. Nathanson (1996)
J. Biol. Chem. 271, 4215-4222
 |  Abstract »  |  Full Text »  |  PDF »

Function of the Human Insulin Promoter in Primary Cultured Islet Cells.

H. Odagiri, J. Wang, and M. S. German (1996)
J. Biol. Chem. 271, 1909-1915
 |  Abstract »  |  Full Text »  |  PDF »

Two Mutations in the Promoter Region of the Human Protein C Gene Both Cause Type I Protein C Deficiency by Disruption of Two HNF-3 Binding Sites.

C. A. Spek, J. S. Greengard, J. H. Griffin, R. M. Bertina, and P. H. Reitsma (1995)
J. Biol. Chem. 270, 24216-24221
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Characterization of the Rat Insulin Enhancer-binding Complex 3b2.

S.-Y. Shieh, C. M. M. Stellrecht, and M.-J. Tsai (1995)
J. Biol. Chem. 270, 21503-21508
 |  Abstract »  |  Full Text »  |  PDF »

Hypoxia Regulates Vascular Endothelial Growth Factor Gene Expression in Endothelial Cells : Identification of a 5' Enhancer.

Y. Liu, S. R. Cox, T. Morita, and S. Kourembanas (1995)
Circ. Res. 77, 638-643
 |  Abstract »  |  Full Text »

Differential Coupling of m2 and m4 Muscarinic Receptors to Inhibition of Adenylyl Cyclase by G[IMAGE][IMAGE] and G[IMAGE][IMAGE] Subunits.

J. C. Migeon, S. L. Thomas, and N. M. Nathanson (1995)
J. Biol. Chem. 270, 16070-16074
 |  Abstract »  |  Full Text »  |  PDF »

Induction and Stabilization of I[IMAGE]B[IMAGE] by Nitric Oxide Mediates Inhibition of NF-[IMAGE]B.

H.-B. Peng, P. Libby, and J. K. Liao (1995)
J. Biol. Chem. 270, 14214-14219
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor..

F J Naya, C M Stellrecht, and M J Tsai (1995)
Genes & Dev. 9, 1009-1019
 |  Abstract »  |  PDF »

A Nuclear Protein in Mesangial Cells That Binds to the Promoter Region of the Platelet-derived Growth Factor-A Chain Gene.

B. Bhandari, U. O. Wenzel, F. Marra, and H. E. Abboud (1995)
J. Biol. Chem. 270, 5541-5548
 |  Abstract »  |  Full Text »  |  PDF »

Cooperativity between an Upstream TATA-like Sequence and a CAA Repeated Element Mediates E1A-dependent Negative Repression of the H-2K^b Class I Gene.

X. Tang, H.-O. Li, O. Sakatsume, T. Ohta, H. Tsutsui, A. F. A. Smit, M. Horikoshi, P. Kourilsky, A. Israël, G. Gachelin, et al. (1995)
J. Biol. Chem. 270, 2327-2336
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-specific and efficient expression of the human simple epithelial keratin 8 gene in transgenic mice.

L Casanova, A Bravo, F Were, A Ramirez, J. Jorcano, and M Vidal (1995)
J. Cell Sci. 108, 811-820
 |  Abstract »  |  PDF »

Direct gene quantitation by PCR reveals differential accumulation of ectopic enzyme in rat-1 cells, v-fos transformants, and revertants..

M B Bahramian and H Zarbl (1994)
Genome Res. 4, 145-153
 |  Abstract »  |  PDF »

microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family..

T J Hemesath, E Steingrimsson, G McGill, M J Hansen, J Vaught, C A Hodgkinson, H Arnheiter, N G Copeland, N A Jenkins, and D E Fisher (1994)
Genes & Dev. 8, 2770-2780
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Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex..

M S German, J Wang, R B Chadwick, and W J Rutter (1992)
Genes & Dev. 6, 2165-2176
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Pan: a transcriptional regulator that binds chymotrypsin, insulin, and AP-4 enhancer motifs..

C Nelson, L P Shen, A Meister, E Fodor, and W J Rutter (1990)
Genes & Dev. 4, 1035-1043
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The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus..

E Martinez-Salas, E Linney, J Hassell, and M L DePamphilis (1989)
Genes & Dev. 3, 1493-1506
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A muscle-specific enhancer is located at the 3' end of the myosin light-chain 1/3 gene locus..

M Donoghue, H Ernst, B Wentworth, B Nadal-Ginard, and N Rosenthal (1988)
Genes & Dev. 2, 1779-1790
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Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer.

I. Akerblom, E. Slater, M Beato, J. Baxter, and P. Mellon (1988)
Science 241, 350-353
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Lens-specific enhancer in the third intron regulates expression of the chicken delta 1-crystallin gene..

S Hayashi, K Goto, T S Okada, and H Kondoh (1987)
Genes & Dev. 1, 818-828
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Regulatory elements that modulate expression of human c-myc..

N Hay, J M Bishop, and D Levens (1987)
Genes & Dev. 1, 659-671
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Sequences in the pea rbcS-3A gene have homology to constitutive mammalian enhancers but function as negative regulatory elements..

C Kuhlemeier, R Fluhr, P J Green, and N H Chua (1987)
Genes & Dev. 1, 247-255
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Factors that interact with the rat albumin promoter are present both in hepatocytes and other cell types..

L E Babiss, R S Herbst, A L Bennett, and J E Darnell (1987)
Genes & Dev. 1, 256-267
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CNS and hypoderm regulatory elements of the Drosophila melanogaster dopa decarboxylase gene.

S. Scholnick, S. Bray, B. Morgan, C. McCormick, and J Hirsh (1986)
Science 234, 998-1002
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Organ-Specific and Light-Induced Expression of Plant Genes.

R. FLUHR, C. KUHLEMEIER, F. NAGY, and N.-H. CHUA (1986)
Science 232, 1106-1112
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Identification of a Basolateral Sorting Signal for the M3 Muscarinic Acetylcholine Receptor in Madin-Darby Canine Kidney Cells.

L. S. Nadler, G. Kumar, and N. M. Nathanson (2001)
J. Biol. Chem. 276, 10539-10547
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SMAD Proteins Transactivate the Human ApoCIII Promoter by Interacting Physically and Functionally with Hepatocyte Nuclear Factor 4.

D. Kardassis, K. Pardali, and V. I. Zannis (2000)
J. Biol. Chem. 275, 41405-41414
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