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Science 8 November 1985:
Vol. 230. no. 4726, pp. 676 - 678
DOI: 10.1126/science.2996144

Articles

Science, Vol 230, Issue 4726, 676-678
Copyright © 1985 by American Association for the Advancement of Science


articles

Wounding and its role in RSV-mediated tumor formation

DS Dolberg, R Hollingsworth, M Hertle, and MJ Bissell

Tumors induced in chickens by Rous sarcoma virus remain localized at the site of injection even though the animals become viremic. Tumors have now been shown to be inducible at other sites if a wound is inflicted or if the tissue is injured by administration of tumor promoters. These findings indicate that local wounding plays a role in the spread of tumorigenicity of Rous sarcoma virus.


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