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Science 27 September 1985:
Vol. 229. no. 4720, pp. 1388 - 1390
DOI: 10.1126/science.2994220
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Articles

Science, Vol 229, Issue 4720, 1388-1390
Copyright © 1985 by American Association for the Advancement of Science

articles

Transcription of novel open reading frames of AIDS retrovirus during infection of lymphocytes

AB Rabson, DF Daugherty, S Venkatesan, KE Boulukos, SI Benn, TM Folks, P Feorino, and MA Martin

The retrovirus frequently isolated from patients with the acquired immune deficiency syndrome (AIDS) has two novel open reading frames previously designated "A" and "B." The "A" region was found to be specifically expressed as polyadenylated RNA's of 5.5 and 5.0 kilobases in infected cells. The "B" region was expressed as 1.8- to 2.0-kilobase RNA species. Additional full-length and spliced messenger RNA's of the env region were also identified.


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