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Science 26 July 1985:
Vol. 229. no. 4711, pp. 402 - 404
DOI: 10.1126/science.229.4711.402
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Articles

Reciprocal Inhibition and Postinhibitory Rebound Produce Reverberation in a Locomotor Pattern Generator

RICHARD A. SATTERLIE 1

1 Department of Zoology, Arizona State University, Tempe 85287, and Friday Harbor Laboratories, Friday Harbor, Washington 98250

The central pattern generator for swimming in the pteropod mollusk Clione limacina consists of at least four pedal interneurons, two each controlling parapodial upstroke and downstroke. The two sets of antagonistic interneurons are linked by reciprocal monosynaptic inhibitory synapses, and all exhibit apparently strong postinhibitory rebound. This simple neuronal network produces reverberating alternate cyclic activity in the absence of tonic drive or apparent feedback modulation.

Submitted on September 10, 1984
Accepted on April 5, 1985


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