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Science 24 May 1985:
Vol. 228. no. 4702, pp. 1013 - 1015
DOI: 10.1126/science.4001929
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Articles

Science, Vol 228, Issue 4702, 1013-1015
Copyright © 1985 by American Association for the Advancement of Science

articles

Intracellular stimulation of an identified neuron evokes cardioacceleratory peptide release

NJ Tublitz and JW Truman

The central nervous system of the tobacco hawkmoth, Manduca sexta, is known to contain two cardioacceleratory peptides (CAP's), both of which function in vivo as cardioregulatory neurohormones. Intracellular electrical stimulation of a single abdominal ganglion neuron evokes the release of CAP-like bioactivity. This stimulation-evoked bioactivity is destroyed by prior treatment with protease. The possibility that intracellular stimulation of a CAP-containing neuron synaptically activated additional spiking neurons is eliminated.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sequence and expression of the CAPA/CAP2b gene in the tobacco hawkmoth, Manduca sexta.
P. K. Loi and N. J. Tublitz (2004)
J. Exp. Biol. 207, 3681-3691
   Abstract »    Full Text »    PDF »
IDENTIFICATION, SEQUENCE AND EXPRESSION OF A CRUSTACEAN CARDIOACTIVE PEPTIDE (CCAP) GENE IN THE MOTH MANDUCA SEXTA.
P. K. LOI, S. A. EMMAL, Y. PARK, and N. J. TUBLITZ (2002)
J. Exp. Biol. 204, 2803-2816
   Abstract »    Full Text »    PDF »
Costorage and Corelease of Modulatory Peptide Cotransmitters with Partially Antagonistic Actions on the Accessory Radula Closer Muscle of Aplysia californica.
F. S. Vilim, D. A. Price, W. Lesser, I. Kupfermann, and K. R. Weiss (1996)
J. Neurosci. 16, 8092-8104
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)