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Science 17 May 1985:
Vol. 228. no. 4701, pp. 799 - 809
DOI: 10.1126/science.2860723
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Articles

Science, Vol 228, Issue 4701, 799-809
Copyright © 1985 by American Association for the Advancement of Science

articles

Positron emission tomography: human brain function and biochemistry

ME Phelps and JC Mazziotta

Positron emission tomography (PET) is an analytical imaging technique that provides a way of making in vivo measurements of the anatomical distribution and rates of specific biochemical reactions. This ability of PET to measure and image dynamic biochemistry builds a bridge between the basic and clinical neurosciences founded on the commonality of the types of measurements made. Clinical findings with PET in humans are suggesting hypotheses that can be tested rigorously in the basic science laboratory.


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