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Science 12 April 1985:
Vol. 228. no. 4696, pp. 143 - 149
DOI: 10.1126/science.3975635
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Articles

Science, Vol 228, Issue 4696, 143-149
Copyright © 1985 by American Association for the Advancement of Science

articles

Neurobiological bases of rhythmic motor acts in vertebrates

S Grillner

The general principles governing the nervous control of innate motor acts in vertebrates are discussed. Particular consideration is given to the control of locomotion in both mammals and lower vertebrates. One in vitro model of the lamprey central nervous system has been developed. It can be maintained in vitro for several days and the motor pattern underlying locomotion can be elicited in isolated sections of the spinal cord. These findings now allow a detailed analysis of the underlying neural mechanisms. The hypothesis that different parts of the network controlling locomotion can be used in a variety of other motor acts, including learned ones, is reviewed.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)