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Science 1 March 1985:
Vol. 227. no. 4690, pp. 1041 - 1044
DOI: 10.1126/science.2858126
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Articles

Science, Vol 227, Issue 4690, 1041-1044
Copyright © 1985 by American Association for the Advancement of Science

articles

Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome

CS Schmaljohn, SE Hasty, JM Dalrymple, JW LeDuc, HW Lee, CH von Bonsdorff, M Brummer-Korvenkontio, A Vaheri, TF Tsai, HL Regnery, and al. et

Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North America, viruses that are antigenically similar to HFRS agents were recently isolated from rodents in the United States. Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.


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