Science 25 January 1985: Vol. 227. no. 4685, pp. 375 - 381 DOI: 10.1126/science.2981433

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Articles

A Mitochondrial Target Sequence Polymorphism in Manganese Superoxide Dismutase Predicts Inferior Survival in Breast Cancer Patients Treated with Cyclophosphamide.

S. A. Glynn, B. J. Boersma, T. M. Howe, H. Edvardsen, S. B. Geisler, J. E. Goodman, L. A. Ridnour, P. E. Lonning, A.-L. Borresen-Dale, B. Naume, et al. (2009)
Clin. Cancer Res. 15, 4165-4173
 |  Abstract »  |  Full Text »  |  PDF »

Advances in Chemical Carcinogenesis: A Historical Review and Prospective.

L. A. Loeb and C. C. Harris (2008)
Cancer Res. 68, 6863-6872
 |  Full Text »  |  PDF »

Reactive Oxygen Species Regulate Hypoxia-Inducible Factor 1{alpha} Differentially in Cancer and Ischemia.

A. A. Qutub and A. S. Popel (2008)
Mol. Cell. Biol. 28, 5106-5119
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells.

J.-H. Park, D. Mangal, K. A. Tacka, A. M. Quinn, R. G. Harvey, I. A. Blair, and T. M. Penning (2008)
PNAS 105, 6846-6851
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of oxidant production in esophageal squamous cell and Barrett's cell lines.

L. A. Feagins, H. Y. Zhang, X. Zhang, K. Hormi-Carver, T. Thomas, L. S. Terada, S. J. Spechler, and R. F. Souza (2008)
Am J Physiol Gastrointest Liver Physiol 294, G411-G417
 |  Abstract »  |  Full Text »  |  PDF »

Lipid Peroxidation, Total Antioxidant Status, and Total Thiol Levels Predict Overall Survival in Patients With Oral Squamous Cell Carcinoma.

B. P. Patel, U. M. Rawal, T. K. Dave, R. M. Rawal, S. N. Shukla, P. M. Shah, and P. S. Patel (2007)
Integr Cancer Ther 6, 365-372
 |  Abstract »  |  PDF »

Cancer stem cell: target for anti-cancer therapy.

C. Tang, B. T. Ang, and S. Pervaiz (2007)
FASEB J 21, 3777-3785
 |  Abstract »  |  Full Text »  |  PDF »

Manganese Superoxide Dismutase Enhances the Invasive and Migratory Activity of Tumor Cells.

K. M. Connor, N. Hempel, K. K. Nelson, G. Dabiri, A. Gamarra, J. Belarmino, L. Van De Water, B. M. Mian, and J. A. Melendez (2007)
Cancer Res. 67, 10260-10267
 |  Abstract »  |  Full Text »  |  PDF »

Polychlorinated Biphenyls Modulated Tumorigenesis in Sprague Dawley Rats: Correlation with Mixed Function Oxidase Activities and Superoxide (O2* ) Formation Potentials and Implied Mode of Action.

J. F. Brown Jr, B. A. Mayes, J. B. Silkworth, and S. B. Hamilton (2007)
Toxicol. Sci. 98, 375-394
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Ionizing Radiation-induced Apoptosis by Mitochondrial NADP+-dependent Isocitrate Dehydrogenase.

J. H. Lee, S. Y. Kim, I. S. Kil, and J.-W. Park (2007)
J. Biol. Chem. 282, 13385-13394
 |  Abstract »  |  Full Text »  |  PDF »

Cyanidin-3-rutinoside, a Natural Polyphenol Antioxidant, Selectively Kills Leukemic Cells by Induction of Oxidative Stress.

R. Feng, H.-M. Ni, S. Y. Wang, I. L. Tourkova, M. R. Shurin, H. Harada, and X.-M. Yin (2007)
J. Biol. Chem. 282, 13468-13476
 |  Abstract »  |  Full Text »  |  PDF »

Interplay between Helicobacter pylori and host gene polymorphisms in inducing oxidative DNA damage in the gastric mucosa.

A. Izzotti, S. De Flora, C. Cartiglia, B. M. Are, M. Longobardi, A. Camoirano, I. Mura, M. P. Dore, A. M. Scanu, P. C. Rocca, et al. (2007)
Carcinogenesis 28, 892-898
 |  Abstract »  |  Full Text »  |  PDF »

Comet Fluorescence in situ Hybridization Analysis for Oxidative Stress-Induced DNA Damage in Colon Cancer Relevant Genes.

M. Glei, A. Schaeferhenrich, U. Claussen, A. Kuechler, T. Liehr, A. Weise, B. Marian, W. Sendt, and B. L. Pool-Zobel (2007)
Toxicol. Sci. 96, 279-284
 |  Abstract »  |  Full Text »  |  PDF »

Disturbance of systemic antioxidant profile in nonsmall cell lung carcinoma.

J. C. Ho, M. Chan-Yeung, S. P. Ho, J. C. Mak, M. S. Ip, G. C. Ooi, M. P. Wong, K. W. Tsang, and W. K. Lam (2007)
Eur. Respir. J. 29, 273-278
 |  Abstract »  |  Full Text »  |  PDF »

DNA Damage by Benzo(a)pyrene in Human Cells Is Increased by Cigarette Smoke and Decreased by a Filter Containing Rosemary Extract, Which Lowers Free Radicals.

K. Alexandrov, M. Rojas, and C. Rolando (2006)
Cancer Res. 66, 11938-11945
 |  Abstract »  |  Full Text »  |  PDF »

Genetic and Cellular Toxicology of Dental Resin Monomers.

H. Schweikl, G. Spagnuolo, and G. Schmalz (2006)
Journal of Dental Research 85, 870-877
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative Stress Induces ADAM9 Protein Expression in Human Prostate Cancer Cells.

S.-Y. Sung, H. Kubo, K. Shigemura, R. S. Arnold, S. Logani, R. Wang, H. Konaka, M. Nakagawa, S. Mousses, M. Amin, et al. (2006)
Cancer Res. 66, 9519-9526
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of 2-Butoxyethanol-Induced Hemangiosarcomas.

S. M. Corthals, L. M. Kamendulis, and J. E. Klaunig (2006)
Toxicol. Sci. 92, 378-386
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Human Tyrosyl-DNA Phosphodiesterase by Aminoglycoside Antibiotics and Ribosome Inhibitors.

Z. Liao, L. Thibaut, A. Jobson, and Y. Pommier (2006)
Mol. Pharmacol. 70, 366-372
 |  Abstract »  |  Full Text »  |  PDF »

Cocoa Polyphenols Inhibit Phorbol Ester-Induced Superoxide Anion Formation in Cultured HL-60 Cells and Expression of Cyclooxygenase-2 and Activation of NF-{kappa}B and MAPKs in Mouse Skin In Vivo.

K. W. Lee, J. K. Kundu, S. O. Kim, K.-S. Chun, H. J. Lee, and Y.-J. Surh (2006)
J. Nutr. 136, 1150-1155
 |  Abstract »  |  Full Text »  |  PDF »

Reactive Oxygen Species-Mediated Mitochondria-to-Nucleus Signaling: A Key to Aging and Radical-Caused Diseases.

P. Storz (2006)
Sci. STKE 2006, re3
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic Manipulation of the Intracellular Redox State.

L. W. Oberley (2006)
Am. Assoc. Cancer Res. Educ. Book 2006, 255-258
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A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis.

M. E. Tome, D. B. F. Johnson, L. M. Rimsza, R. A. Roberts, T. M. Grogan, T. P. Miller, L. W. Oberley, and M. M. Briehl (2005)
Blood 106, 3594-3601
 |  Abstract »  |  Full Text »  |  PDF »

Temporal changes of multiple redox couples from proliferation to growth arrest in IEC-6 intestinal epithelial cells.

M. S. Attene-Ramos, K. Kitiphongspattana, K. Ishii-Schrade, and H. R. Gaskins (2005)
Am J Physiol Cell Physiol 289, C1220-C1228
 |  Abstract »  |  Full Text »  |  PDF »

Abnormalities in Nitric Oxide and Its Derivatives in Lung Cancer.

F. A. Masri, S. A. A. Comhair, T. Koeck, W. Xu, A. Janocha, S. Ghosh, R. A. Dweik, J. Golish, M. Kinter, D. J. Stuehr, et al. (2005)
Am. J. Respir. Crit. Care Med. 172, 597-605
 |  Abstract »  |  Full Text »  |  PDF »

Evidence that iron overload plus croton oil induce skin tumours in mice.

H Rezazadeh, A R Nayebi, A Garjani, A Sheikhulislami, and H Babaei (2005)
Human and Experimental Toxicology 24, 409-413
 |  Abstract »  |  PDF »

Loss-of-Function of Nkx3.1 Promotes Increased Oxidative Damage in Prostate Carcinogenesis.

X. Ouyang, T. L. DeWeese, W. G. Nelson, and C. Abate-Shen (2005)
Cancer Res. 65, 6773-6779
 |  Abstract »  |  Full Text »  |  PDF »

Butyrate may enhance toxicological defence in primary, adenoma and tumor human colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics.

B. L. Pool-Zobel, V. Selvaraju, J. Sauer, T. Kautenburger, J. Kiefer, K. K. Richter, M. Soom, and S. Wolfl (2005)
Carcinogenesis 26, 1064-1076
 |  Abstract »  |  Full Text »  |  PDF »

Genomic instability in radial growth phase melanoma cell lines after ultraviolet irradiation.

M R Hussein, A K Haemel, O Sudilovsky, and G S Wood (2005)
J. Clin. Pathol. 58, 389-396
 |  Abstract »  |  Full Text »  |  PDF »

The emperor wears no clothes in the field of carcinogen risk assessment: ignored concepts in cancer risk assessment.

J. E. Trosko and B. L. Upham (2005)
Mutagenesis 20, 81-92
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Phospholipid-hydroperoxide Glutathione Peroxidase in Human Dermal Fibroblasts Abrogates UVA Irradiation-induced Expression of Interstitial Collagenase/Matrix Metalloproteinase-1 by Suppression of Phosphatidylcholine Hydroperoxide-mediated NF{kappa}B Activation and Interleukin-6 Release.

J. Wenk, J. Schuller, C. Hinrichs, T. Syrovets, N. Azoitei, M. Podda, M. Wlaschek, P. Brenneisen, L.-A. Schneider, A. Sabiwalsky, et al. (2004)
J. Biol. Chem. 279, 45634-45642
 |  Abstract »  |  Full Text »  |  PDF »

The adaptive imbalance to genotoxic stress: genome guardians rear their ugly heads.

L. J. Hofseth (2004)
Carcinogenesis 25, 1787-1793
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C{delta} Regulates Keratinocyte Death and Survival by Regulating Activity and Subcellular Localization of a p38{delta}-Extracellular Signal-Regulated Kinase 1/2 Complex.

T. Efimova, A.-M. Broome, and R. L. Eckert (2004)
Mol. Cell. Biol. 24, 8167-8183
 |  Abstract »  |  Full Text »  |  PDF »

In vivo Detection of Gastric Cancer in Rats by Electron Paramagnetic Resonance Imaging.

T. Mikuni, G. He, S. Petryakov, M. M. Fallouh, Y. Deng, R. Ishihara, P. Kuppusamy, M. Tatsuta, and J. L. Zweier (2004)
Cancer Res. 64, 6495-6502
 |  Abstract »  |  Full Text »  |  PDF »

The use of N-t-butyl hydroxylamine for radioprotection in cultured cells and mice.

J. H. Lee, I. S. Kim, and J.-W. Park (2004)
Carcinogenesis 25, 1435-1442
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of Oxidative Stress and Nitric Oxide Levels in Patients with Oral Cavity Cancer.

S. S. S. Beevi, A. M. H. Rasheed, and A. Geetha (2004)
Jpn. J. Clin. Oncol. 34, 379-385
 |  Abstract »  |  Full Text »  |  PDF »

Modification of Proteins by Isoketal-containing Oxidized Phospholipids.

C. J. Brame, O. Boutaud, S. S. Davies, T. Yang, J. A. Oates, D. Roden, and L. J. Roberts II (2004)
J. Biol. Chem. 279, 13447-13451
 |  Abstract »  |  Full Text »  |  PDF »

p53-Induced Up-Regulation of MnSOD and GPx but not Catalase Increases Oxidative Stress and Apoptosis.

S. P. Hussain, P. Amstad, P. He, A. Robles, S. Lupold, I. Kaneko, M. Ichimiya, S. Sengupta, L. Mechanic, S. Okamura, et al. (2004)
Cancer Res. 64, 2350-2356
 |  Abstract »  |  Full Text »  |  PDF »

Dietary Zinc Alters Early Inflammatory Responses during Cutaneous Wound Healing in Weanling CD-1 Mice.

Y. Lim, M. Levy, and T. M. Bray (2004)
J. Nutr. 134, 811-816
 |  Abstract »  |  Full Text »  |  PDF »

Resveratrol Inhibits Drug-Induced Apoptosis in Human Leukemia Cells by Creating an Intracellular Milieu Nonpermissive for Death Execution.

K. A. Ahmad, M.-V. Clement, I. M. Hanif, and S. Pervaiz (2004)
Cancer Res. 64, 1452-1459
 |  Abstract »  |  Full Text »  |  PDF »

Imexon-Induced Apoptosis in Multiple Myeloma Tumor Cells Is Caspase-8 Dependent.

A. M. Evens, S. Prachand, B. Shi, M. Paniaqua, L. I. Gordon, and R. B. Gartenhaus (2004)
Clin. Cancer Res. 10, 1481-1491
 |  Abstract »  |  Full Text »  |  PDF »

p53-Mediated Oxidative Stress and Apoptosis: S. PERWEZ HUSSAIN, PAUL AMSTAD, PEIJUN HE, ANA ROBLES, SHAWN LUPOLD, SAGAR SENGUPTA, MASATO ICHIMIYA, SHU OKAMURA, MATHEW MOAKE, KATHLEEN FORRESTER, AND CURTIS C. HARRIS, Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland 20892.

(2004)
Toxicol Pathol 32, 163-164
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Resveratrol: from grapevines to mammalian biology.

S. PERVAIZ (2003)
FASEB J 17, 1975-1985
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Effects of Hydrogen Peroxide upon Nicotinamide Nucleotide Metabolism in Escherichia coli: CHANGES IN ENZYME LEVELS AND NICOTINAMIDE NUCLEOTIDE POOLS AND STUDIES OF THE OXIDATION OF NAD(P)H BY Fe(III).

J. L. Brumaghim, Y. Li, E. Henle, and S. Linn (2003)
J. Biol. Chem. 278, 42495-42504
 |  Abstract »  |  Full Text »  |  PDF »

Protective Role of {alpha}-Phenyl-N-t-butylnitrone against Ionizing Radiation in U937 Cells and Mice.

J. H. Lee and J.-W. Park (2003)
Cancer Res. 63, 6885-6893
 |  Abstract »  |  Full Text »  |  PDF »

The usefulness of cytogenetic parameters, level of p53 protein and endogenous glutathione as intermediate end-points in raw betel-nut genotoxicity.

K Kumpawat and A Chatterjee (2003)
Human and Experimental Toxicology 22, 363-371
 |  Abstract »  |  PDF »

Nonproteic Antioxidant Status in Plasma of Subjects with Colon Cancer.

C. Di Giacomo, R. Acquaviva, R. Lanteri, F. Licata, A. Licata, and A. Vanella (2003)
Experimental Biology and Medicine 228, 525-528
 |  Abstract »  |  Full Text »  |  PDF »

Malgun (Clear) Cell Change in Helicobacter pylori Gastritis Reflects Epithelial Genomic Damage and Repair.

J. Jang, S. Lee, Y. Jung, K. Song, M. Fukumoto, V. E. Gould, and I. Lee (2003)
Am. J. Pathol. 162, 1203-1211
 |  Abstract »  |  Full Text »  |  PDF »

DNA Fingerprinting Abnormalities Can Distinguish Ulcerative Colitis Patients with Dysplasia and Cancer from Those Who Are Dysplasia/Cancer-Free.

R. Chen, P. S. Rabinovitch, D. A. Crispin, M. J. Emond, K. M. Koprowicz, M. P. Bronner, and T. A. Brentnall (2003)
Am. J. Pathol. 162, 665-672
 |  Abstract »  |  Full Text »  |  PDF »

Tomato Sauce Supplementation and Prostate Cancer: Lycopene Accumulation and Modulation of Biomarkers of Carcinogenesis.

P. Bowen, L. Chen, M. Stacewicz-Sapuntzakis, C. Duncan, R. Sharifi, L. Ghosh, H.-S. Kim, K. Christov-Tzelkov, and R. van Breemen (2002)
Experimental Biology and Medicine 227, 886-893
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative damage and cytogenetic analysis in leukocytes of Parkinson's disease patients.

L. Migliore, L. Petrozzi, C. Lucetti, G. Gambaccini, S. Bernardini, R. Scarpato, F. Trippi, R. Barale, G. Frenzilli, V. Rodilla, et al. (2002)
Neurology 58, 1809-1815
 |  Abstract »  |  Full Text »  |  PDF »

Diphenyleneiodonium Triggers the Efflux of Glutathione from Cultured Cells.

J. M. Pullar and M. B. Hampton (2002)
J. Biol. Chem. 277, 19402-19407
 |  Abstract »  |  Full Text »  |  PDF »

Correlation between antioxidant status, tumorigenicity and radiosensitivity in sister rat cell lines.

A. Bravard, A. Ageron-Blanc, S. Alvarez, P. Drane, Y. le Rhun, F. Paris, C. Luccioni, and E. May (2002)
Carcinogenesis 23, 705-711
 |  Abstract »  |  Full Text »  |  PDF »

H2O2 Induces a Transient Multi-phase Cell Cycle Arrest in Mouse Fibroblasts through Modulating Cyclin D and p21Cip1 Expression.

K. Barnouin, M. L. Dubuisson, E. S. Child, S. Fernandez de Mattos, J. Glassford, R. H. Medema, D. J. Mann, and E. W.-F. Lam (2002)
J. Biol. Chem. 277, 13761-13770
 |  Abstract »  |  Full Text »  |  PDF »

Association of the hOGG1 Ser326Cys Polymorphism with Lung Cancer Risk.

L. Le Marchand, T. Donlon, A. Lum-Jones, A. Seifried, and L. R. Wilkens (2002)
Cancer Epidemiol. Biomarkers Prev. 11, 409-412
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Glutathione Depletion on Antitumor Drug Toxicity (Apoptosis and Necrosis) in U-937 Human Promonocytic Cells. THE ROLE OF INTRACELLULAR OXIDATION.

A. Troyano, C. Fernandez, P. Sancho, E. de Blas, and P. Aller (2001)
J. Biol. Chem. 276, 47107-47115
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression of Manganese Superoxide Dismutase and Catalase in Lung Cancer.

J. C.-m. Ho, S. Zheng, S. A. A. Comhair, C. Farver, and S. C. Erzurum (2001)
Cancer Res. 61, 8578-8585
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates.

H. Rubin (2001)
Carcinogenesis 22, 1903-1930
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), suppress H-ras mutations and aneuploidy in a murine skin carcinogenesis model.

M. Hanausek, P. Ganesh, Z. Walaszek, C. J. Arntzen, T. J. Slaga, and J. U. Gutterman (2001)
PNAS 98, 11551-11556
 |  Abstract »  |  Full Text »  |  PDF »

Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappa B by inhibiting both its nuclear localization and ability to bind DNA.

V. Haridas, C. J. Arntzen, and J. U. Gutterman (2001)
PNAS 98, 11557-11562
 |  Abstract »  |  Full Text »  |  PDF »

Role of iron-dextran on 7,12-dimethylbenz(a) anthracene-initiated and croton oil-promoted cutaneous tumorigenesis in normal and pregnant mice.

H Rezazadeh, A R Nayebi, and M Athar (2001)
Human and Experimental Toxicology 20, 471-476
 |  Abstract »  |  PDF »

Potent inactivation of representative members of each PKC isozyme subfamily and PKD via S-thiolation by the tumor-promotion/progression antagonist glutathione but not by its precursor cysteine.

F. Chu, N. E. Ward, and C. A. O'Brian (2001)
Carcinogenesis 22, 1221-1229
 |  Abstract »  |  Full Text »  |  PDF »

Heterozygosity for the Mouse Apex Gene Results in Phenotypes Associated with Oxidative Stress.

L. B. Meira, S. Devaraj, G. E. Kisby, D. K. Burns, R. L. Daniel, R. E. Hammer, S. Grundy, I. Jialal, and E. C. Friedberg (2001)
Cancer Res. 61, 5552-5557
 |  Abstract »  |  Full Text »  |  PDF »

Interactions of Selenium Compounds with Other Antioxidants in DNA Damage and Apoptosis in Human Normal Keratinocytes.

C.-L. Shen, W. Song, and B. C. Pence (2001)
Cancer Epidemiol. Biomarkers Prev. 10, 385-390
 |  Abstract »  |  Full Text »

Case-Control Study of Ovarian Cancer and Polymorphisms in Genes Involved in Catecholestrogen Formation and Metabolism.

M. T. Goodman, K. McDuffie, L. N. Kolonel, K. Terada, T. A. Donlon, L. R. Wilkens, C. Guo, and L. Le Marchand (2001)
Cancer Epidemiol. Biomarkers Prev. 10, 209-216
 |  Abstract »  |  Full Text »

Catalase-overexpressing Thymocytes Are Resistant to Glucocorticoid-induced Apoptosis and Exhibit Increased Net Tumor Growth.

M. E. Tome, A. F. Baker, G. Powis, C. M. Payne, and M. M. Briehl (2001)
Cancer Res. 61, 2766-2773
 |  Abstract »  |  Full Text »

Ceramide: A Potential Mediator of Apoptosis in Human Retinal Pigment Epithelial Cells.

A. Barak, L. S. Morse, and T. Goldkorn (2001)
Invest. Ophthalmol. Vis. Sci. 42, 247-254
 |  Abstract »  |  Full Text »

Potentiation of epidermal growth factor-induced DNA synthesis in rat hepatocytes by phenobarbitone: possible involvement of oxidative stress and kinase activation.

N.J. Hodges, T.C. Orton, A.J. Strain, and J.K. Chipman (2000)
Carcinogenesis 21, 2041-2047
 |  Abstract »  |  Full Text »  |  PDF »

A Role for Protein Kinase C-{{delta}} in the Regulation of Ornithine Decarboxylase Expression by Oxidative Stress.

M. A. Otieno and T. W. Kensler (2000)
Cancer Res. 60, 4391-4396
 |  Abstract »  |  Full Text »

Urea protects from the proapoptotic effect of NaCl in renal medullary cells.

Z. Zhang, W. Tian, and D. M. Cohen (2000)
Am J Physiol Renal Physiol 279, F345-F352
 |  Abstract »  |  Full Text »  |  PDF »

Superoxide Dismutases in Gastric and Esophageal Cancer and the Prognostic Impact in Gastric Cancer.

A. Miranda, L. Janssen, C. B. Bosman, W. van Duijn, M. M. Oostendorp-van de Ruit, F. J. G. M. Kubben, G. Griffioen, C. B. H. W. Lamers, J. Han, J. M. van Krieken, et al. (2000)
Clin. Cancer Res. 6, 3183-3192
 |  Abstract »  |  Full Text »

Cannabinoids Protect Cells from Oxidative Cell Death: A Receptor-Independent Mechanism.

Y. Chen and J. Buck (2000)
J. Pharmacol. Exp. Ther. 293, 807-812
 |  Abstract »  |  Full Text »

Nuclear Localization of Catechol-O-Methyltransferase in Neoplastic and Nonneoplastic Mammary Epithelial Cells.

J. Weisz, G. Fritz-Wolz, S. Gestl, G. A. Clawson, C. R. Creveling, J. G. Liehr, and D. Dabbs (2000)
Am. J. Pathol. 156, 1841-1848
 |  Abstract »  |  Full Text »  |  PDF »

Oxidant Stress Stimulates Phosphorylation of eIF4E without an Effect on Global Protein Synthesis in Smooth Muscle Cells. LACK OF EVIDENCE FOR A ROLE OF H2O2 IN ANGIOTENSIN II-INDUCED HYPERTROPHY.

G. N. Rao (2000)
J. Biol. Chem. 275, 16993-16999
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondria of Saccharomyces cerevisiae Contain One-conserved Cysteine Type Peroxiredoxin with Thioredoxin Peroxidase Activity.

J. R. Pedrajas, A. Miranda-Vizuete, N. Javanmardy, J.-A. Gustafsson, and G. Spyrou (2000)
J. Biol. Chem. 275, 16296-16301
 |  Abstract »  |  Full Text »  |  PDF »

Endogenous Interleukin-18 Modulates Immune Escape of Murine Melanoma Cells by Regulating the Expression of Fas Ligand and Reactive Oxygen Intermediates.

D. Cho, H. Song, Y. M. Kim, D. Houh, D. Y. Hur, H. Park, D. Yoon, K. H. Pyun, W. J. Lee, M. Kurimoto, et al. (2000)
Cancer Res. 60, 2703-2709
 |  Abstract »  |  Full Text »

Cloning and Expression of the Bioluminescent Photoprotein Pholasin from the Bivalve Mollusc Pholas dactylus.

S. L. Dunstan, G. B. Sala-Newby, A. B. Fajardo, K. M. Taylor, and A. K. Campbell (2000)
J. Biol. Chem. 275, 9403-9409
 |  Abstract »  |  Full Text »  |  PDF »

Genotoxic Polycyclic Aromatic Hydrocarbon ortho-Quinones Generated by Aldo-Keto Reductases Induce CYP1A1 via Nuclear Translocation of the Aryl Hydrocarbon Receptor.

M. E. Burczynski and T. M. Penning (2000)
Cancer Res. 60, 908-915
 |  Abstract »  |  Full Text »

Intake of Flavonoids and Lung Cancer.

L. Le Marchand, S. P. Murphy, J. H. Hankin, L. R. Wilkens, and L. N. Kolonel (2000)
J Natl Cancer Inst 92, 154-160
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Activation of the Human Manganese Superoxide Dismutase Gene Mediated by Tetradecanoylphorbol Acetate.

H.-P. Kim, J.-H. Roe, P. B. Chock, and M. B. Yim (1999)
J. Biol. Chem. 274, 37455-37460
 |  Abstract »  |  Full Text »  |  PDF »

A Retrospective Study of Late Outcome in Patients with Peripheral Arterial Occlusive Disease: An Association Between Prosthetic Vascular Graft and Cancer Death?.

Y. Yoshitomi, S. Kojima, T. Umemoto, Y. Hosoi, M. Kuramochi, and Y. Yoshitomi (1999)
Angiology 50, 1007-1015
 |  Abstract »  |  PDF »

Role of Oxyradicals in Mutagenicity and DNA Damage Induced by Crocidolite Asbestos in Mammalian Cells.

A. Xu, L.-J. Wu, R. M. Santella, and T. K. Hei (1999)
Cancer Res. 59, 5922-5926
 |  Abstract »  |  Full Text »  |  PDF »

Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters.

S. Kumar and A. Holmgren (1999)
Carcinogenesis 20, 1761-1767
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Antioxidants on Androgen-Induced AP-1 and NF-{kappa}B DNA-Binding Activity in Prostate Carcinoma Cells.

M. O. Ripple, W. F. Henry, S. R. Schwarze, G. Wilding, and R. Weindruch (1999)
J Natl Cancer Inst 91, 1227-1232
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of DNA Strand Breaks, Oxidized Bases, and Glutathione S-Transferase P1 in Human Colon Cells from Biopsies.

B. L. Pool-Zobel, S. L. Abrahamse, A. R. Collins, W. Kark, R. Gugler, D. Oberreuther, E. G. Siegel, S. T.-v. Lishaut, and G. Rechkemmer (1999)
Cancer Epidemiol. Biomarkers Prev. 8, 609-614
 |  Abstract »  |  Full Text »

Oxidative Stress Triggers STAT3 Tyrosine Phosphorylation and Nuclear Translocation in Human Lymphocytes.

M. Carballo, M. Conde, R. El Bekay, J. Martin-Nieto, M. J. Camacho, J. Monteseirin, J. Conde, F. J. Bedoya, and F. Sobrino (1999)
J. Biol. Chem. 274, 17580-17586
 |  Abstract »  |  Full Text »  |  PDF »

Chemopreventive effect of 4'-demethyl epipodophyllotoxin on DMBA/TPA-induced mouse skin carcinogenesis.

D. Dhawan, S. Balasubramanian, A. J. Amonkar, and N. Singh (1999)
Carcinogenesis 20, 997-1003
 |  Abstract »  |  Full Text »  |  PDF »

Chemoprevention by curcumin during the promotion stage of tumorigenesis of mammary gland in rats irradiated with {gamma}-rays.

H. Inano, M. Onoda, N. Inafuku, M. Kubota, Y. Kamada, T. Osawa, H. Kobayashi, and K. Wakabayashi (1999)
Carcinogenesis 20, 1011-1018
 |  Abstract »  |  Full Text »  |  PDF »

Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones.

O. Ullrich, T. Reinheckel, N. Sitte, R. Hass, T. Grune, and K. J. A. Davies (1999)
PNAS 96, 6223-6228
 |  Abstract »  |  Full Text »  |  PDF »

17ß-Estradiol Reduces Glycoxidative Damage in the Artery Wall.

B. A. Walsh, B. L. Busch, A. E. Mullick, K. M. Reiser, and J. C. Rutledge (1999)
Arterioscler. Thromb. Vasc. Biol. 19, 840-846
 |  Abstract »  |  Full Text »  |  PDF »

Tomatoes, Tomato-Based Products, Lycopene, and Cancer: Review of the Epidemiologic Literature.

E. Giovannucci (1999)
J Natl Cancer Inst 91, 317-331
 |  Abstract »  |  Full Text »  |  PDF »

Isoform-specific Induction of a Human Aldo-Keto Reductase by Polycyclic Aromatic Hydrocarbons (PAHs), Electrophiles, and Oxidative Stress: Implications for the Alternative Pathway of PAH Activation Catalyzed by Human Dihydrodiol Dehydrogenase.

M. E. Burczynski, H.-K. Lin, and T. M. Penning (1999)
Cancer Res. 59, 607-614
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Glutathione Levels and Oxidoresistance Mediated by Increased Glucose-6-phosphate Dehydrogenase Expression.

F. Salvemini, A. Franze, A. Iervolino, S. Filosa, S. Salzano, and M. V. Ursini (1999)
J. Biol. Chem. 274, 2750-2757
 |  Abstract »  |  Full Text »  |  PDF »

Is arcA3 a possible mediator in the signal transduction pathway during agonist cell cycle arrest by salicylic acid and UV irradiation?.

C Perennes, N Glab, B Guglieni, M. Doutriaux, T. Phan, S Planchais, and C Bergounioux (1999)
J. Cell Sci. 112, 1181-1190
 |  Abstract »  |  PDF »

Induction of microsatellite instability by oxidative DNA damage.

A. L. Jackson, R. Chen, and L. A. Loeb (1998)
PNAS 95, 12468-12473
 |  Abstract »  |  Full Text »  |  PDF »

The Iron Chelator L1 Potentiates Oxidative DNA Damage in Iron-Loaded Liver Cells.

L. Cragg, R. P. Hebbel, W. Miller, A. Solovey, S. Selby, and H. Enright (1998)
Blood 92, 632-638
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Ferritin Protects DNA From UV Damage in Corneal Epithelial Cells.

C. X. Cai, D. E. Birk, and T. F. Linsenmayer (1998)
Mol. Biol. Cell 9, 1037-1051
 |  Abstract »  |  Full Text »

Balance between Endogenous Superoxide Stress and Antioxidant Defenses.

A. S. Gort and J. A. Imlay (1998)
J. Bacteriol. 180, 1402-1410
 |  Abstract »  |  Full Text »

H2O2 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells.

T Goldkorn, N Balaban, M Shannon, V Chea, K Matsukuma, D Gilchrist, H Wang, and C Chan (1998)
J. Cell Sci. 111, 3209-3220
 |  Abstract »  |  PDF »

Superoxide accelerates DNA damage by elevating free-iron levels.

K. Keyer and J. A. Imlay (1996)
PNAS 93, 13635-13640
 |  Abstract »  |  Full Text »  |  PDF »

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