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Science 11 January 1985: Vol. 227. no. 4683, pp. 134 - 140 DOI: 10.1126/science.3917574
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Articles
Science, Vol 227, Issue 4683, 134-140
Copyright © 1985 by American Association for the Advancement of Science
B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo
A Ephrussi,
GM Church,
S Tonegawa,
and
W Gilbert
The mouse heavy chain immunoglobulin gene contains a tissue-specific enhancer. The enhancer and flanking sequences were studied in vivo by carrying out dimethyl sulfate protection experiments on living cells, in combination with genomic sequencing. Relative to reactions on naked DNA, there are changes (protections and enhancements) in the reactivity of guanine residues to dimethyl sulfate within the enhancer sequence in myeloma, B, and early B cells, whereas virtually no alterations appear in cells of non-B lineage. Most of the affected residues are in four clusters, in sequences homologous to the octamer 5'CAGGTGGC 3' (C, cytosine; A, adenine; G. guanine; T, thymine). The alterations in the pattern of G reactivity are consistent with the tissue-specific binding of molecules to the mouse immunoglobulin heavy chain enhancer.
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| PDF »
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| Abstract »
| PDF »
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- T Jenuwein and R Grosschedl (1991)
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5, 932-943
| Abstract »
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- G P Pfeifer and A D Riggs (1991)
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| Abstract »
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| Abstract »
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4, 1404-1415
| Abstract »
| PDF »
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248, 480-483
| Abstract »
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- T J Brennan and E N Olson (1990)
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4, 582-595
| Abstract »
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4, 167-179
| Abstract »
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- P Henthorn, M Kiledjian, and T Kadesch (1990)
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247, 467-470
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- P. Mueller and B Wold (1989)
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246, 780-786
| Abstract »
| PDF »
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- G. Pfeifer, S. Steigerwald, P. Mueller, B Wold, and A. Riggs (1989)
Science
246, 810-813
| Abstract »
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- L Zhang and J D Gralla (1989)
Genes & Dev.
3, 1814-1822
| Abstract »
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- J. Mellentin, C Murre, T. Donlon, P. McCaw, S. Smith, A. Carroll, M. McDonald, D Baltimore, and M. Cleary (1989)
Science
246, 379-382
| Abstract »
| PDF »
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- J H LeBowitz, R G Clerc, M Brenowitz, and P A Sharp (1989)
Genes & Dev.
3, 1625-1638
| Abstract »
| PDF »
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- R H Scheuermann and U Chen (1989)
Genes & Dev.
3, 1255-1266
| Abstract »
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- M Briskin, M. Kuwabara, D. Sigman, and R Wall (1988)
Science
242, 1036-1037
| Abstract »
| PDF »
- I kappa B: a specific inhibitor of the NF-kappa B transcription factor.
- P. Baeuerle and D Baltimore (1988)
Science
242, 540-546
| Abstract »
| PDF »
- Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro..
- J H LeBowitz, T Kobayashi, L Staudt, D Baltimore, and P A Sharp (1988)
Genes & Dev.
2, 1227-1237
| Abstract »
| PDF »
- Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting..
- P R Mueller, S J Salser, and B Wold (1988)
Genes & Dev.
2, 412-427
| Abstract »
| PDF »
- Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor.
- C Nelson, V. Albert, H. Elsholtz, L. Lu, and M. Rosenfeld (1988)
Science
239, 1400-1405
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- Phorbol-ester-induced Activation of the NF-{kappa}B Transcription Factor Involves Dissociation of an Apparently Cytoplasmic NF-{kappa}B/Inhibitor Complex.
- P.A. Baeuerle, M. Lenardo, J.W. Pierce, and D. Baltimore (1988)
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53, 789-798
| Abstract »
| PDF »
- Telomeric DNA-protein interactions of Oxytricha macronuclear DNA..
- C M Price and T R Cech (1987)
Genes & Dev.
1, 783-793
| Abstract »
| PDF »
- In vitro binding of several cell-specific and ubiquitous nuclear proteins to the GT-I motif of the SV40 enhancer..
- J H Xiao, I Davidson, M Macchi, R Rosales, M Vigneron, A Staub, and P Chambon (1987)
Genes & Dev.
1, 794-807
| Abstract »
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- Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility.
- M Lenardo, J. Pierce, and D Baltimore (1987)
Science
236, 1573-1577
| Abstract »
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- Regulation of inducible and tissue-specific gene expression.
- T Maniatis, S Goodbourn, and J. Fischer (1987)
Science
236, 1237-1245
| Abstract »
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- U Pauli, S Chrysogelos, G Stein, J Stein, and H Nick (1987)
Science
236, 1308-1311
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- P F Johnson, W H Landschulz, B J Graves, and S L McKnight (1987)
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- T. Parslow, S. Jones, B Bond, and K. Yamamoto (1987)
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235, 1498-1501
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- Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters.
- H. Elsholtz, H. Mangalam, E Potter, V. Albert, S Supowit, R. Evans, and M. Rosenfeld (1986)
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- S. Scholnick, S. Bray, B. Morgan, C. McCormick, and J Hirsh (1986)
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- I Kovesdi, R Reichel, and Nevins JR (1986)
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- Repression of the immunoglobulin heavy chain enhancer by the adenovirus-2 E1A products.
- R Hen, E Borrelli, and P Chambon (1985)
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- Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements.
- T Edlund, M. Walker, P. Barr, and W. Rutter (1985)
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230, 912-916
| Abstract »
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- Plasticity of the differentiated state.
- H. Blau, G. Pavlath, E. Hardeman, C. Chiu, L Silberstein, S. Webster, S. Miller, and C Webster (1985)
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230, 758-766
| Abstract »
| PDF »
- Contribution of promoter to tissue-specific expression of the mouse immunoglobulin kappa gene.
- T. Gopal, T Shimada, A. Baur, and A. Nienhuis (1985)
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229, 1102-1104
| Abstract »
| PDF »
- Active T-cell receptor genes have intron deoxyribonuclease hypersensitive sites.
- E Bier, Y Hashimoto, M. Greene, and A. Maxam (1985)
Science
229, 528-534
| Abstract »
| PDF »
- PU.1-mediated Transcription Is Enhanced by HMG-I(Y)-dependent Structural Mechanisms.
- R. T. Lewis, A. Andreucci, and B. S. Nikolajczyk (2001)
J. Biol. Chem.
276, 9550-9557
| Abstract »
| Full Text »
| PDF »
- Transcriptional Activation by a Matrix Associating Region-binding Protein. CONTEXTUAL REQUIREMENTS FOR THE FUNCTION OF BRIGHT.
- M. H. Kaplan, R.-T. Zong, R. F. Herrscher, R. H. Scheuermann, and P. W. Tucker (2001)
J. Biol. Chem.
276, 21325-21330
| Abstract »
| Full Text »
| PDF »
- Promoter Regulatory Elements and DNase I-hypersensitive Sites Involved in Serglycin Proteoglycan Gene Expression in Human Erythroleukemia, CHRF 288-11, and HL-60 Cells.
- B. P. Schick, I. Petrushina, K. C. Brodbeck, and P. Castronuevo (2001)
J. Biol. Chem.
276, 24726-24735
| Abstract »
| Full Text »
| PDF »
|
|