Science 30 November 1984: Vol. 226. no. 4678, pp. 1097 - 1099 DOI: 10.1126/science.6093263

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Articles

Anti-apoptotic Molecule Bcl-2 Regulates the Differentiation, Activation, and Survival of Both Osteoblasts and Osteoclasts.

Y. Nagase, M. Iwasawa, T. Akiyama, Y. Kadono, M. Nakamura, Y. Oshima, T. Yasui, T. Matsumoto, J. Hirose, H. Nakamura, et al. (2009)
J. Biol. Chem. 284, 36659-36669
 |  Abstract »  |  Full Text »  |  PDF »

Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes.

G. A. Calin and C. M. Croce (2009)
Blood 114, 4761-4770
 |  Abstract »  |  Full Text »  |  PDF »

A single nucleotide polymorphism determines protein isoform production of the human c-FLIP protein.

N. Ueffing, K. K. Singh, A. Christians, C. Thorns, A. C. Feller, F. Nagl, F. Fend, S. Heikaus, A. Marx, R. B. Zotz, et al. (2009)
Blood 114, 572-579
 |  Abstract »  |  Full Text »  |  PDF »

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma.

M. Saito, U. Novak, E. Piovan, K. Basso, P. Sumazin, C. Schneider, M. Crespo, Q. Shen, G. Bhagat, A. Califano, et al. (2009)
PNAS 106, 11294-11299
 |  Abstract »  |  Full Text »  |  PDF »

Clinicopathological features of lymphoma/leukemia patients carrying both BCL2 and MYC translocations.

N. Tomita, M. Tokunaka, N. Nakamura, K. Takeuchi, J. Koike, S. Motomura, K. Miyamoto, A. Kikuchi, R. Hyo, Y. Yakushijin, et al. (2009)
Haematologica 94, 935-943
 |  Abstract »  |  Full Text »  |  PDF »

Bcl-2 family on guard at the ER.

E. Szegezdi, D. C. MacDonald, T. Ni Chonghaile, S. Gupta, and A. Samali (2009)
Am J Physiol Cell Physiol 296, C941-C953
 |  Abstract »  |  Full Text »  |  PDF »

Retinoid Chemoprevention Trials: Cyclin D1 in the Crosshairs.

S. J. Freemantle, Y. Guo, and E. Dmitrovsky (2009)
Cancer Prevention Research 2, 3-6
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Genome-wide profiling of follicular lymphoma by array comparative genomic hybridization reveals prognostically significant DNA copy number imbalances.

K.-J. J. Cheung, S. P. Shah, C. Steidl, N. Johnson, T. Relander, A. Telenius, B. Lai, K. P. Murphy, W. Lam, A. J. Al-Tourah, et al. (2009)
Blood 113, 137-148
 |  Abstract »  |  Full Text »  |  PDF »

G0 Function of BCL2 and BCL-xL Requires BAX, BAK, and p27 Phosphorylation by Mirk, Revealing a Novel Role of BAX and BAK in Quiescence Regulation.

Y. Janumyan, Q. Cui, L. Yan, C. G. Sansam, M. Valentin, and E. Yang (2008)
J. Biol. Chem. 283, 34108-34120
 |  Abstract »  |  Full Text »  |  PDF »

In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas.

K. D. Mason, C. J. Vandenberg, C. L. Scott, A. H. Wei, S. Cory, D. C. S. Huang, and A. W. Roberts (2008)
PNAS 105, 17961-17966
 |  Abstract »  |  Full Text »  |  PDF »

IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma.

K. R. Calvo, B. Dabir, A. Kovach, C. Devor, R. Bandle, A. Bond, J. H. Shih, and E. S. Jaffe (2008)
Blood 112, 3818-3826
 |  Abstract »  |  Full Text »  |  PDF »

Chromosomal translocations: revisited yet again.

J. D. Rowley (2008)
Blood 112, 2183-2189
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B lymphocytes: how they develop and function.

T. W. LeBien and T. F. Tedder (2008)
Blood 112, 1570-1580
 |  Abstract »  |  Full Text »  |  PDF »

MicroRNA-Cancer Connection: The Beginning of a New Tale.

G. A. Calin and C. M. Croce (2008)
Am. Assoc. Cancer Res. Educ. Book 2008, 667-675
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Bcl-x in Ph+ B-ALL increases cellular proliferation and does not inhibit leukemogenesis.

J. G. Harb, B. I. Chyla, and C. S. Huettner (2008)
Blood 111, 3760-3769
 |  Abstract »  |  Full Text »  |  PDF »

BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia.

V. Del Gaizo Moore, K. D. Schlis, S. E. Sallan, S. A. Armstrong, and A. Letai (2008)
Blood 111, 2300-2309
 |  Abstract »  |  Full Text »  |  PDF »

Bcl-2 Overexpression in Thyroid Carcinoma Cells Increases Sensitivity to Bcl-2 Homology 3 Domain Inhibition.

C. S. Mitsiades, P. Hayden, V. Kotoula, D. W. McMillin, C. McMullan, J. Negri, J. E. Delmore, V. Poulaki, and N. Mitsiades (2007)
J. Clin. Endocrinol. Metab. 92, 4845-4852
 |  Abstract »  |  Full Text »  |  PDF »

Bcl-2 over-expression promotes genomic instability by inhibiting apoptosis of cells exposed to hydrogen peroxide.

A. G. Cox and M. B. Hampton (2007)
Carcinogenesis 28, 2166-2171
 |  Abstract »  |  Full Text »  |  PDF »

Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs.

Y. Tambe, A. Yoshioka-Yamashita, K.-i. Mukaisho, S. Haraguchi, T. Chano, T. Isono, T. Kawai, Y. Suzuki, R. Kushima, T. Hattori, et al. (2007)
Carcinogenesis 28, 777-784
 |  Abstract »  |  Full Text »  |  PDF »

Surviving sepsis: bcl-2 overexpression modulates splenocyte transcriptional responses in vivo.

T. H. Wagner, A. M. Drewry, S. MacMillan, W. M. Dunne, K. C. Chang, I. E. Karl, R. S. Hotchkiss, and J. P. Cobb (2007)
Am J Physiol Regulatory Integrative Comp Physiol 292, R1751-R1759
 |  Abstract »  |  Full Text »  |  PDF »

Syk-dependent mTOR activation in follicular lymphoma cells.

L. Leseux, S. M. Hamdi, T. al Saati, F. Capilla, C. Recher, G. Laurent, and C. Bezombes (2006)
Blood 108, 4156-4162
 |  Abstract »  |  Full Text »  |  PDF »

Pax2/5/8 proteins promote cell survival in C. elegans.

D. Park, H. Jia, V. Rajakumar, and H. M. Chamberlin (2006)
Development 133, 4193-4202
 |  Abstract »  |  Full Text »  |  PDF »

MicroRNA-Cancer Connection: The Beginning of a New Tale..

G. A. Calin and C. M. Croce (2006)
Cancer Res. 66, 7390-7394
 |  Abstract »  |  Full Text »  |  PDF »

miR-15 and miR-16 induce apoptosis by targeting BCL2.

A. Cimmino, G. A. Calin, M. Fabbri, M. V. Iorio, M. Ferracin, M. Shimizu, S. E. Wojcik, R. I. Aqeilan, S. Zupo, M. Dono, et al. (2005)
PNAS 102, 13944-13949
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Pathogenesis of Follicular Lymphoma: A Cross Talk of Genetic and Immunologic Factors.

D. de Jong (2005)
J. Clin. Oncol. 23, 6358-6363
 |  Abstract »  |  Full Text »  |  PDF »

Polyploid Formation via Chromosome Duplication Induced by CTP:Phosphocholine Cytidylyltransferase Deficiency and Bcl-2 Overexpression: Identification of Two Novel Endogenous Factors.

Y.-J. Shen, C. J. DeLong, F. Terce, T. Kute, M. C. Willingham, M. J. Pettenati, and Z. Cui (2005)
J. Histochem. Cytochem. 53, 725-733
 |  Abstract »  |  Full Text »  |  PDF »

Markers of apoptosis in stage IB squamous cervical carcinoma.

G Van de Putte, R Holm, A K Lie, M Baekelandt, and G B Kristensen (2005)
J. Clin. Pathol. 58, 590-594
 |  Abstract »  |  Full Text »  |  PDF »

Lymphoma associated chromosomal abnormalities can easily be detected by FISH on tissue imprints. An underused diagnostic alternative.

I Buno, P Nava, A Alvarez-Doval, F Alvarez-Rodriguez, J L Diez-Martin, and J Menarguez (2005)
J. Clin. Pathol. 58, 629-633
 |  Abstract »  |  Full Text »  |  PDF »

Targeting Apoptosis Pathways in Cancer Therapy.

I. M. Ghobrial, T. E. Witzig, and A. A. Adjei (2005)
CA Cancer J Clin 55, 178-194
 |  Abstract »  |  Full Text »  |  PDF »

EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX.

T. Grimm, S. Schneider, E. Naschberger, J. Huber, E. Guenzi, A. Kieser, P. Reitmeir, T. F. Schulz, C. A. Morris, and M. Sturzl (2005)
Blood 105, 3263-3269
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of apoptosis by bcl-2 overexpression in lymphoid cells of transgenic zebrafish.

D. M. Langenau, C. Jette, S. Berghmans, T. Palomero, J. P. Kanki, J. L. Kutok, and A. T. Look (2005)
Blood 105, 3278-3285
 |  Abstract »  |  Full Text »  |  PDF »

Novel chromosomal imbalances in mantle cell lymphoma detected by genome-wide array-based comparative genomic hybridization.

M. Schraders, R. Pfundt, H. M. P. Straatman, I. M. Janssen, A. G. van Kessel, E. F. P. M. Schoenmakers, J. H. J. M. van Krieken, and P. J. T. A. Groenen (2005)
Blood 105, 1686-1693
 |  Abstract »  |  Full Text »  |  PDF »

BCL2 protein expression parallels its mRNA level in normal and malignant B cells.

Y. Shen, J. Iqbal, J. Z. Huang, G. Zhou, and W. C. Chan (2004)
Blood 104, 2936-2939
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative Proteomic and Transcriptional Analysis of the Response to the p38 Mitogen-activated Protein Kinase Inhibitor SB203580 in Transformed Follicular Lymphoma Cells.

Z. Lin, D. K. Crockett, S. D. Jenson, M. S. Lim, and K. S. J. Elenitoba-Johnson (2004)
Mol. Cell. Proteomics 3, 820-833
 |  Abstract »  |  Full Text »  |  PDF »

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die.

P. G. Ekert, S. H. Read, J. Silke, V. S. Marsden, H. Kaufmann, C. J. Hawkins, R. Gerl, S. Kumar, and D. L. Vaux (2004)
J. Cell Biol. 165, 835-842
 |  Abstract »  |  Full Text »  |  PDF »

Alkylating DNA damage stimulates a regulated form of necrotic cell death.

W.-X. Zong, D. Ditsworth, D. E. Bauer, Z.-Q. Wang, and C. B. Thompson (2004)
Genes & Dev. 18, 1272-1282
 |  Abstract »  |  Full Text »  |  PDF »

Bim is a suppressor of Myc-induced mouse B cell leukemia.

A. Egle, A. W. Harris, P. Bouillet, and S. Cory (2004)
PNAS 101, 6164-6169
 |  Abstract »  |  Full Text »  |  PDF »

VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia.

A. Egle, A. W. Harris, M. L. Bath, L. O'Reilly, and S. Cory (2004)
Blood 103, 2276-2283
 |  Abstract »  |  Full Text »  |  PDF »

Hyperphosphorylation of a Mitochondrial Protein, Prohibitin, Is Induced by Calyculin A in a Rice Lesion-Mimic Mutant cdr1.

A. Takahashi, T. Kawasaki, H. L. Wong, U. Suharsono, H. Hirano, and K. Shimamoto (2003)
Plant Physiology 132, 1861-1869
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy.

K. S. J. Elenitoba-Johnson, S. D. Jenson, R. T. Abbott, R. A. Palais, S. D. Bohling, Z. Lin, S. Tripp, P. J. Shami, L. Y. Wang, R. W. Coupland, et al. (2003)
PNAS 100, 7259-7264
 |  Abstract »  |  Full Text »  |  PDF »

Par-4 Transcriptionally Regulates Bcl-2 through a WT1-binding Site on the bcl-2 Promoter.

S. K. Cheema, S. K. Mishra, V. M. Rangnekar, A. M. Tari, R. Kumar, and G. Lopez-Berestein (2003)
J. Biol. Chem. 278, 19995-20005
 |  Abstract »  |  Full Text »  |  PDF »

Cell cycle deregulation in B-cell lymphomas.

M. Sanchez-Beato, A. Sanchez-Aguilera, and M. A. Piris (2003)
Blood 101, 1220-1235
 |  Abstract »  |  Full Text »  |  PDF »

Chromosomal translocation t(11;18)(q21;q21) in gastrointestinal mucosa associated lymphoid tissue lymphoma.

S Nakamura, T Matsumoto, S Nakamura, Y Jo, K Fujisawa, H Suekane, T Yao, M Tsuneyoshi, and M Iida (2003)
J. Clin. Pathol. 56, 36-42
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Diagnostics.

R. M. Braziel, M. A. Shipp, A. L. Feldman, V. Espina, M. Winters, E. S. Jaffe, E. F. Petricoin III, and L. A. Liotta (2003)
Hematology 2003, 279-293
 |  Abstract »  |  Full Text »  |  PDF »

BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens.

G. Z. Rassidakis, L. J. Medeiros, T. P. Vassilakopoulos, S. Viviani, V. Bonfante, G. Nadali, M. Herling, M. K. Angelopoulou, R. Giardini, M. Chilosi, et al. (2002)
Blood 100, 3935-3941
 |  Abstract »  |  Full Text »  |  PDF »

Insights into the molecular pathogenesis of follicular lymphoma arising from analysis of geographic variation.

J. J. Biagi and J. F. Seymour (2002)
Blood 99, 4265-4275
 |  Abstract »  |  Full Text »  |  PDF »

p53AIP1 Regulates the Mitochondrial Apoptotic Pathway.

K. Matsuda, K. Yoshida, Y. Taya, K. Nakamura, Y. Nakamura, and H. Arakawa (2002)
Cancer Res. 62, 2883-2889
 |  Abstract »  |  Full Text »  |  PDF »

Fibroblast Growth Factor-2 Induces Translational Regulation of Bcl-XL and Bcl-2 via a MEK-dependent Pathway. CORRELATION WITH RESISTANCE TO ETOPOSIDE-INDUCED APOPTOSIS.

O. E. Pardo, A. Arcaro, G. Salerno, S. Raguz, J. Downward, and M. J. Seckl (2002)
J. Biol. Chem. 277, 12040-12046
 |  Abstract »  |  Full Text »  |  PDF »

Detection of BCL2 Rearrangements in Follicular Lymphoma.

J. C. Aster and J. A. Longtine (2002)
Am. J. Pathol. 160, 759-763
 |  Abstract »  |  Full Text »  |  PDF »

High Frequency of t(14;18)-Translocation Breakpoints Outside of Major Breakpoint and Minor Cluster Regions in Follicular Lymphomas : Improved Polymerase Chain Reaction Protocols for Their Detection.

A. Albinger-Hegyi, B. Hochreutener, M.-T. Abdou, I. Hegyi, M. T. Dours-Zimmermann, M. O. Kurrer, P. U. Heitz, and D. R. Zimmermann (2002)
Am. J. Pathol. 160, 823-832
 |  Abstract »  |  Full Text »  |  PDF »

Genetic synthetic lethality screen at the single gene level in cultured human cells.

A. H. Simons, N. Dafni, I. Dotan, Y. Oron, and D. Canaani (2001)
Nucleic Acids Res. 29, e100
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the 13q14 Tumor Suppressor Locus in CLL: Identification of ALT1, an Alternative Splice Variant of the LEU2 Gene.

F. Bullrich, H. Fujii, G. Calin, H. Mabuchi, M. Negrini, Y. Pekarsky, L. Rassenti, H. Alder, J. C. Reed, M. J. Keating, et al. (2001)
Cancer Res. 61, 6640-6648
 |  Abstract »  |  Full Text »  |  PDF »

Lack of correlation between numbers of circulating t(14;18)-positive cells and response to first-line treatment in follicular lymphoma.

C. M. P. W. Mandigers, J. P. P. Meijerink, E. J. B. M. Mensink, E. L. R. T. M. Tonnissen, K. M. Hebeda, M. J. J. T. Bogman, and J. M. M. Raemaekers (2001)
Blood 98, 940-944
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression of BCL-2 Family Proteins in ALK-Positive and ALK-Negative Anaplastic Large Cell Lymphoma of T/Null-Cell Lineage.

G. Z. Rassidakis, A. H. Sarris, M. Herling, R. J. Ford, F. Cabanillas, T. J. McDonnell, and L. J. Medeiros (2001)
Am. J. Pathol. 159, 527-535
 |  Abstract »  |  Full Text »

Apoptosis Induction by the Photosensitizer Verteporfin: Identification of Mitochondrial Adenine Nucleotide Translocator as a Critical Target.

A.-S. Belzacq, E. Jacotot, H. L. A. Vieira, D. Mistro, D. J. Granville, Z. Xie, J. C. Reed, G. Kroemer, and C. Brenner (2001)
Cancer Res. 61, 1260-1264
 |  Abstract »  |  Full Text »

Regulation of Bcl2 Phosphorylation and Potential Significance for Leukemic Cell Chemoresistance.

X. Deng, S. M. Kornblau, P. P. Ruvolo, and W. S. May Jr. (2000)
J Natl Cancer Inst Monographs 2000, 30-37
 |  Abstract »  |  Full Text »  |  PDF »

Cell Death Induction by CTL: Perforin/Granzyme B System Dominantly Acts for Cell Death Induction in Human Hepatocellular Carcinoma Cells.

M. Hayashida, H. Kawano, T. Nakano, K. Shiraki, and A. Suzuki (2000)
Experimental Biology and Medicine 225, 143-150
 |  Abstract »  |  Full Text »

Bcl-2 antiapoptotic protein mediates verotoxin II-induced cell death: possible association between Bcl-2 and tissue failure by E. coli O157:H7.

A. Suzuki, H. Doi, F. Matsuzawa, S.-i. Aikawa, K. Takiguchi, H. Kawano, M. Hayashida, and S. Ohno (2000)
Genes & Dev. 14, 1734-1740
 |  Abstract »  |  Full Text »

Herpesvirus papio encodes a functional homologue of the Epstein-Barr virus apoptosis suppressor, BHRF1.

C. A. Meseda, J. R. Arrand, and M. Mackett (2000)
J. Gen. Virol. 81, 1801-1805
 |  Abstract »  |  Full Text »

Incidence and Subtype Specificity of API2-MALT1 Fusion Translocations in Extranodal, Nodal, and Splenic Marginal Zone Lymphomas.

E. D. Remstein, C. D. James, and P. J. Kurtin (2000)
Am. J. Pathol. 156, 1183-1188
 |  Abstract »  |  Full Text »  |  PDF »

Apoptosis in cancer.

S. W. Lowe and A. W. Lin (2000)
Carcinogenesis 21, 485-495
 |  Abstract »  |  Full Text »  |  PDF »

Tetrocarcin A Inhibits Mitochondrial Functions of Bcl-2 and Suppresses Its Anti-apoptotic Activity.

T. Nakashima, M. Miura, and M. Hara (2000)
Cancer Res. 60, 1229-1235
 |  Abstract »  |  Full Text »

Simian Virus 40 Large T Antigen Binds a Novel Bcl-2 Homology Domain 3-containing Proapoptosis Protein in the Cytoplasm.

S.-C. Tsai, K. B. S. Pasumarthi, L. Pajak, M. Franklin, B. Patton, H. Wang, W. J. Henzel, J. T. Stults, and L. J. Field (2000)
J. Biol. Chem. 275, 3239-3246
 |  Abstract »  |  Full Text »  |  PDF »

Molecular and Clinical Features of Non-Burkitt’s, Diffuse Large-Cell Lymphoma of B-Cell Type Associated With the c-MYC/Immunoglobulin Heavy-Chain Fusion Gene.

T. Akasaka, H. Akasaka, C. Ueda, N. Yonetani, Y. Maesako, A. Shimizu, H. Yamabe, S. Fukuhara, T. Uchiyama, and H. Ohno (2000)
J. Clin. Oncol. 18, 510
 |  Abstract »  |  Full Text »  |  PDF »

DNA-damage-induced Checkpoint Pathways in the Nematode Caenorhabditis elegans.

E.R. HOFMANN, S. MILSTEIN, and M.O. HENGARTNER (2000)
Cold Spring Harb Symp Quant Biol 65, 467-474
 |  Abstract »  |  PDF »

Editorial: Mcl-1--Just Another Antiapoptotic Bcl-2 Homolog?.

A. L. Johnson (1999)
Endocrinology 140, 5465-5468
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Clinicopathogenetic Significance of Chromosomal Abnormalities in Patients With Blastic Peripheral B-Cell Lymphoma.

B. Schlegelberger, T. Zwingers, L. Harder, H. Nowotny, R. Siebert, M. Vesely, H. Bartels, R. Sonnen, G. Hopfinger, A. Nader, et al. (1999)
Blood 94, 3114-3120
 |  Abstract »  |  Full Text »  |  PDF »

Tamoxifen-induced Apoptosis in Breast Cancer Cells Relates to Down-Regulation of bcl-2, but not bax and bcl-XL, without Alteration of p53 Protein Levels.

G.-J. Zhang, I. Kimijima, M. Onda, M. Kanno, H. Sato, T. Watanabe, A. Tsuchiya, R. Abe, and S. Takenoshita (1999)
Clin. Cancer Res. 5, 2971-2977
 |  Abstract »  |  Full Text »  |  PDF »

Life and Death in Otolaryngology: Mechanisms of Apoptosis and Its Role in the Pathology and Treatment of Disease.

S. P. Mostafapour, D. M. Hockenbery, and E. W Rubel (1999)
Arch Otolaryngol Head Neck Surg 125, 729-737
 |  Abstract »  |  Full Text »  |  PDF »

Impairment of the Proapoptotic Activity of Bax by Missense Mutations Found in Gastrointestinal Cancers.

J. Gil, H. Yamamoto, J. M. Zapata, J. C. Reed, and M. Perucho (1999)
Cancer Res. 59, 2034-2037
 |  Abstract »  |  Full Text »  |  PDF »

Expression of E2A-HLF Chimeric Protein Induced T-Cell Apoptosis, B-Cell Maturation Arrest, and Development of Acute Lymphoblastic Leukemia.

H. Honda, T. Inaba, T. Suzuki, H. Oda, Y. Ebihara, K. Tsuiji, T. Nakahata, T. Ishikawa, Y. Yazaki, and H. Hirai (1999)
Blood 93, 2780-2790
 |  Abstract »  |  Full Text »  |  PDF »

Correlation of Bcl-2 Rearrangement With Clinical Characteristics and Outcome in Indolent Follicular Lymphoma.

A. Lopez-Guillermo, F. Cabanillas, T. I. McDonnell, P. McLaughlin, T. Smith, W. Pugh, F. Hagemeister, M. A. Rodriguez, J. E. Romaguera, A. Younes, et al. (1999)
Blood 93, 3081-3087
 |  Abstract »  |  Full Text »  |  PDF »

Optimal Proliferation of a Hematopoietic Progenitor Cell Line Requires Either Costimulation With Stem Cell Factor or Increase of Receptor Expression That Can Be Replaced by Overexpression of Bcl-2.

H.-M. Huang, J.-C. Li, Y.-C. Hsieh, H.-F. Yang-Yen, and J. J.-Y. Yen (1999)
Blood 93, 2569-2577
 |  Abstract »  |  Full Text »  |  PDF »

Tumorigenic Conversion Resulting from Inhibition of Apoptosis in a Nontumorigenic HeLa-derived Hybrid Cell Line.

K. Oka, B. Qi, and M. Yutsudo (1999)
Cancer Res. 59, 1816-1819
 |  Abstract »  |  Full Text »  |  PDF »

Glucocorticoids inhibit serum depletion-induced apoptosis in T lymphocytes expressing Bcl-2.

S.-T. J. HUANG and J. A. CIDLOWSKI (1999)
FASEB J 13, 467-476
 |  Abstract »  |  Full Text »

Rapid Simultaneous Amplification and Detection of the MBR/JH Chromosomal Translocation by Fluorescence Melting Curve Analysis.

S. D. Bohling, T. C. King, C. T. Wittwer, and K. S. J. Elenitoba-Johnson (1999)
Am. J. Pathol. 154, 97-103
 |  Abstract »  |  Full Text »  |  PDF »

Trans-chromosomal recombination within the Ig heavy chain switch region in B lymphocytes.

M. Kingzette, H. Spieker-Polet, P.-C. Yam, S.-K. Zhai, and K. L. Knight (1998)
PNAS 95, 11840-11845
 |  Abstract »  |  Full Text »  |  PDF »

Immune Reconstitution and Immunotherapy After Autologous Hematopoietic Stem Cell Transplantation.

T. Guillaume, D. B. Rubinstein, and M. Symann (1998)
Blood 92, 1471-1490
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The Bcl-2 Protein Family: Arbiters of Cell Survival.

J. M. Adams and S. Cory (1998)
Science 281, 1322-1326
 |  Abstract »  |  Full Text »

Delta 9-Tetrahydrocannabinol Induces Apoptosis in Macrophages and Lymphocytes: Involvement of Bcl-2 and Caspase-1.

W. Zhu, H. Friedman, and T. W. Klein (1998)
J. Pharmacol. Exp. Ther. 286, 1103-1109
 |  Abstract »  |  Full Text »

Homozygous Deletions at Chromosome 9p21 Involving p16 and p15 Are Associated With Histologic Progression in Follicle Center Lymphoma.

K. S.J. Elenitoba-Johnson, R. D. Gascoyne, M. S. Lim, M. Chhanabai, E. S. Jaffe, and M. Raffeld (1998)
Blood 91, 4677-4685
 |  Abstract »  |  Full Text »  |  PDF »

Changing Patterns of Gene Expression Identify Multiple Steps During Regression of Rat Prostate in Vivo.

J. Gubbay, J. P. Doyle, M. Skinner, and N. Heintz (1998)
Endocrinology 139, 2935-2943
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Demonstration of Kaposi's Sarcoma-Associated Herpes Virus Cyclin D Homolog in Cutaneous Kaposi's Sarcoma by Colorimetric In Situ Hybridization Using a Catalyzed Signal Amplification System.

J. A. Reed, R. G. Nador, D. Spaulding, Y. Tani, E. Cesarman, and D. M. Knowles (1998)
Blood 91, 3825-3832
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The Clinical Significance of Molecular Response in Indolent Follicular Lymphomas.

A. Lopez-Guillermo, F. Cabanillas, P. McLaughlin, T. Smith, F. Hagemeister, M. A. Rodriguez, J. E. Romaguera, A. Younes, A. H. Sarris, H. A. Preti, et al. (1998)
Blood 91, 2955-2960
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Molecular Cloning of Translocation t(1;14)(q21;q32) Defines a Novel Gene (BCL9) at Chromosome 1q21.

T.G. Willis, I.R. Zalcberg, L.J.A. Coignet, I. Wlodarska, M. Stul, D.M. Jadayel, C. Bastard, J.G. Treleaven, D. Catovsky, M.L.M. Silva, et al. (1998)
Blood 91, 1873-1881
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BCL-2 Expression Correlates With Lower Proliferative Activity in the Intermediate- and High-Grade Non-Hodgkin's Lymphomas: An Eastern Cooperative Oncology Group and Southwest Oncology Group Cooperative Laboratory Study.

J. N. Winter, J. Andersen, J. C. Reed, S. Krajewski, D. Variakojis, K. D. Bauer, R. I. Fisher, L. I. Gordon, M. M. Oken, S. Jiang, et al. (1998)
Blood 91, 1391-1398
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Long-Lived B Cells Are Distinguished by Elevated Expression of A1.

M. M. Tomayko and M. P. Cancro (1998)
J. Immunol. 160, 107-111
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Unbalanced Expression of Bcl-2 Family Proteins in Follicular Lymphoma: Contribution of CD40 Signaling in Promoting Survival.

P. Ghia, V. A. Boussiotis, J. L. Schultze, A. A. Cardoso, D. M. Dorfman, J. G. Gribben, A. S. Freedman, and L. M. Nadler (1998)
Blood 91, 244-251
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BCL2 Overexpression Associated With Chromosomal Amplification in Diffuse Large B-Cell Lymphoma.

O. Monni, H. Joensuu, K. Franssila, J. Klefstrom, K. Alitalo, and S. Knuutila (1997)
Blood 90, 1168-1174
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The antisense bcl-2-IgH transcript is an optimal target for synthetic oligonucleotides.

S. Morelli, D. Delia, S. Capaccioli, A. Quattrone, N. Schiavone, A. Bevilacqua, S. Tomasini, and A. Nicolin (1997)
PNAS 94, 8150-8155
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The Ig Heavy Chain Gene Is Frequently Involved in Chromosomal Translocations in Multiple Myeloma and Plasma Cell Leukemia as Detected by In Situ Hybridization.

K. Nishida, A. Tamura, N. Nakazawa, Y. Ueda, T. Abe, F. Matsuda, K. Kashima, and M. Taniwaki (1997)
Blood 90, 526-534
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Prognostic Significance of Bcl-2 Protein Expression and Bcl-2 Gene Rearrangement in Diffuse Aggressive Non-Hodgkin's Lymphoma.

R. D. Gascoyne, S. A. Adomat, S. Krajewski, M. Krajewska, D. E. Horsman, A. W. Tolcher, S. E. O'Reilly, P. Hoskins, A. J. Coldman, J. C. Reed, et al. (1997)
Blood 90, 244-251
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Nonionic Detergents Induce Dimerization among Members of the Bcl-2 Family.

Y.-T. Hsu and R. J. Youle (1997)
J. Biol. Chem. 272, 13829-13834
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CD6 Ligation Modulates the Bcl-2/Bax Ratio and Protects Chronic Lymphocytic Leukemia B Cells From Apoptosis Induced by Anti-IgM.

L. M. Osorio, A. De Santiago, M. Aguilar-SantelisesHa, k. Mellstedt, and M. Jondal (1997)
Blood 89, 2833-2841
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Molecular Monitoring of Minimal Residual Disease in Follicular and Mantle Cell Non-Hodgkin's Lymphomas Treated With High-Dose Chemotherapy and Peripheral Blood Progenitor Cell Autografting.

P. Corradini, M. Astolfi, C. Cherasco, M. Ladetto, C. Voena, D. Caracciolo, A. Pileri, and C. Tarella (1997)
Blood 89, 724-491
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Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma.

P. L. Bergsagel, M. Chesi, E. Nardini, L. A. Brents, S. L. Kirby, and W. M. Kuehl (1996)
PNAS 93, 13931-13936
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Bcl-2 Expression in Neural Cells Blocks Activation of ICE/CED-3 Family Proteases during Apoptosis.

A. Srinivasan, L. M. Foster, M.-P. Testa, T. Ord, R. W. Keane, D. E. Bredesen, and C. Kayalar (1996)
J. Neurosci. 16, 5654-5660
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REVIEW {blacksquare} : Keeping Neurons Alive: The Molecular Control of Apoptosis (Part II.

D. E. Bredesen (1996)
Neuroscientist 2, 211-216
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Bcl-2 protein localizes to the chromosomes of mitotic nuclei and is correlated with the cell cycle in cultured epithelial cell lines.

Q. Lu, A. Hanby, M. Nasser Hajibagheri, S. Gschmeissner, P. Lu, J Taylor-Papadimitriou, S Krajewski, J. Reed, and N. Wright (1994)
J. Cell Sci. 107, 363-371
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Programmed cell death and the control of cell survival: lessons from the nervous system.

M. Raff, B. Barres, J. Burne, H. Coles, Y Ishizaki, and M. Jacobson (1993)
Science 262, 695-700
 |  Abstract »  |  PDF »

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