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Science 26 October 1984:
Vol. 226. no. 4673, pp. 451 - 453
DOI: 10.1126/science.6208608
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Articles

Science, Vol 226, Issue 4673, 451-453
Copyright © 1984 by American Association for the Advancement of Science

articles

HTLV-III in the semen and blood of a healthy homosexual man

DD Ho, RT Schooley, TR Rota, JC Kaplan, T Flynn, SZ Salahuddin, MA Gonda, and MS Hirsch

Human T-lymphotropic virus type III (HTLV-III) is the probable etiologic agent for the acquired immune deficiency syndrome (AIDS). HTLV-III was isolated from semen and blood of a healthy homosexual man whose serum contains antibodies to HTLV-III. The finding of virus in semen supports epidemiologic data that suggest that AIDS can be transmitted sexually. In addition, the demonstration of HTLV-III in the blood and semen of a healthy individual establishes an asymptomatic, virus-positive carrier state which may be important in the dissemination of HTLV-III and, consequently, AIDS.


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Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene.
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The Acquired Immunodeficiency Syndrome: An Update.
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