Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 19 October 1984:
Vol. 226. no. 4672, pp. 312 - 318
DOI: 10.1126/science.226.4672.312
Prev | Table of Contents | Next

Articles

Chemical Sensing in Process Analysis

T. Hirschfeld 1, J. B. Callis 2, and B. R. Kowalski 2

1 Staff scientist at Lawrence Livermore National Laboratory and affiliate professor of chemistry at the University of Washington., Member of the Center for Process Analytical Chemistry at the University of Washington, Seattle 98195.
2 Research professor and professor of chemistry, respectively, at the University of Washington., Member of the Center for Process Analytical Chemistry at the University of Washington, Seattle 98195.

Improvements in process control, which determine production efficiency and product quality, are critically dependent upon on-line process analysis. The technology of the required instrumentation will be substantially expanded by advances in sensing devices. In the future, the hardware will consist of sensor arrays and miniaturized instruments fabricated by microlithography and silicon micromachining. Chemometrics will be extensively used in software to provide error detection, selfcalibration, and correction as well as multivariate data analysis for the determination of anticipated and unanticipated species. A number of examples of monolithically fabricated sensors now exist and more will be forthcoming as the new paradigms and new tools are widely adopted. A trend toward not only on-line but even in-product sensors is becoming discernible.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Instrumentation in the Next Decade.
T. Hirschfeld (1985)
Science 230, 286-291
   Abstract »    PDF »
Trends in analytical instrumentation.
F. McLafferty (1984)
Science 226, 251-253
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)