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Science 19 October 1984:
Vol. 226. no. 4672, pp. 288 - 298
DOI: 10.1126/science.6385252
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Articles

Science, Vol 226, Issue 4672, 288-298
Copyright © 1984 by American Association for the Advancement of Science

articles

Nuclear magnetic resonance technology for medical studies

TF Budinger and PC Lauterbur

Nuclear magnetic resonance proton imaging provides anatomical definition of normal and abnormal tissues with a contrast and detection sensitivity superior to those of x-ray computed tomography in the human head and pelvis and parts of the cardiovascular and musculoskeletal systems. Recent improvements in technology should lead to advances in diagnostic imaging of the breast and regions of the abdomen. Selected-region nuclear magnetic resonance spectroscopy of protons, carbon-13, and phosphorus-31 has developed into a basic science tool for in vivo studies on man and a unique tool for clinical diagnoses of metabolic disorders. At present, nuclear magnetic resonance is considered safe if access to the magnet environment is controlled. Technological advances employing field strengths over 2 teslas will require biophysical studies of heating and static field effects.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
An In Vivo Study of Phosphorus and Glucose Metabolism in Alzheimer's Disease Using Magnetic Resonance Spectroscopy and PET.
D. G. M. Murphy, P. A. Bottomley, J. A. Salerno, C. DeCarli, M. J. Mentis, C. L. Grady, D. Teichberg, K. R. Giacometti, J. M. Rosenberg, C. J. Hardy, et al. (1993)
Arch Gen Psychiatry 50, 341-349
   Abstract »    PDF »
Functional magnetic resonance imaging in medicine and physiology.
C. Moonen, P. van Zijl, J. Frank, D Le Bihan, and E. Becker (1990)
Science 250, 53-61
   Abstract »    PDF »


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