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Science 19 October 1984:
Vol. 226. no. 4672, pp. 275 - 281
DOI: 10.1126/science.6385251
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Articles

Science, Vol 226, Issue 4672, 275-281
Copyright © 1984 by American Association for the Advancement of Science

articles

High-performance liquid chromatography-mass spectrometry

ML Vestal

Techniques for on-line coupling of high-performance liquid chromatography with mass spectrometry are reviewed with particular emphasis on those suitable for application to nonvolatile samples. The present status of various techniques is summarized and the strengths and weaknesses of the various approaches are assessed. The potential for future application of recently developed techniques for combined liquid chromatography and mass spectrometry is discussed.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Drug Metab. Dispos. 36, 1977-1982
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Trends in analytical instrumentation.
F. McLafferty (1984)
Science 226, 251-253
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Trends in Analytical Scale Separations.
J. W. Jorgenson (1984)
Science 226, 254-261
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